• 대한예방의학회:학술대회논문집
• /
• 대한예방의학회 2002년도 제54차 추계 학술대회 연제집
• /
• pp.429-430
• /
• 2002

• 대한예방의학회:학술대회논문집
• /
• 대한예방의학회 2002년도 제54차 추계 학술대회 연제집
• /
• pp.354-355
• /
• 2002

• 한국환경보건학회지
• /
• 제35권6호
• /
• pp.538-541
• /
• 2009

Humans have a long history of asbestos use. There are reports from the Roman era, of asbestos victims among the slaves who worked in asbestos mines. The fact that asbestos can induce lung cancer and mesothelioma was verified epidemiologically in the 1960s. Asbestos related diseases are predominantly occupational in nature but can be caused by environmental exposure. Environmental mesothelioma is mainly associated with tremolite asbestos and this information comes from many countries including Turkey, Greece, Corsica, New Caledonia and Cyprus. In 1993, the first case of mesothelioma in Korea was reported in an asbestos textile worker. Recently, some asbestos disease victims who lived near an asbestos factory have their cases before the courts. A series of recent asbestos-related events in Korea, for example, the shocking revelation of asbestos containing talc in baby powders have caused the general public to become aware of the health risks of asbestos exposure. Asbestos related diseases are characterized by a long latency period, especially, mesothelioma which has no threshold of safety. Hence the best strategy for preventing asbestos related diseases is to decrease asbestos exposure levels to as low as possible.

• 한국환경보건학회지
• /
• 제33권1호
• /
• pp.30-35
• /
• 2007

Waste policies with waste metering system and recycling in 1995 have contributed to the reduction of solid waste generation. Now rural areas as well as urban areas produce less amount of solid wastes in terms of per capita. However most policies in relation to waste issue have been concentrated in urban areas. Large portion of agricultural waste in rural region are being illegally treated such as open incineration or burned out on the road. In this study, we assessed the atmospheric air quality and health risk by illegal open incineration in rural region. In case of benzene level, worst concentration during illegal open incineration was 0.23 ppm and cancer risk by exposure was estimated to $2.29{\times}10^{-3}$.

• 월간산업보건
• /
• 통권63호
• /
• pp.27-32
• /
• 1993

직업과 질병간의 관련성이 역학적인 방법에 의하여 밝혀진 대표적인 예로 직업성 암을 들수 있다. 실제로 이러한 노력에 의하여 현재에 이르러는 작업장에서 사용되는 몇가지 물질들이 발암성물질로 분류(Recogniz Human Carcinogen)되어 있다. 이 글은 Monson이 저술한 'Occupational Epidemiology'중에서 'Occupation and cancer'의 첫 부분과, 암발생과의 관련성이 확립된 직업성 폭로물질들을 열거한 표를 번역한 것이다. 내용중에서도 언급하고 있듯이 화학군(group of chemicals)이 제시된 경우에는 그 군에 속한 모든 화학물질들이 발암원성 물질이라는 것은 아니고, 작업공정이 열거된 예에서도 그 공정에서 어떠한 물질이 과연 발암성인지를 밝혀내기에 충분한 정보가 아직 없다. 그러나 직업과 암에 관한 역학적 연구의 역사적인 배경, 현 상태 등을 파악하는데에 좋은 자료일 것으로 생각되어 게재하고자 한다. - 저자 주 -

• Asian Pacific Journal of Cancer Prevention
• /
• 제16권7호
• /
• pp.2745-2749
• /
• 2015

Objective: To study the PLCE1 gene rs2274223 polymorphism with regard to esophageal cancer and its interaction with diet, lifestyle, psychological and environmental factors in Southwest Shandong province. Materials and Methods: A case series study (case-case) was conducted. Questionnaire data were collected and 3 ml-5ml venous blood was drawn for DNA extraction among the qualified research subjects. PLCE1 gene polymorphism was detected after PCR amplification of DNA. SPSS 13.0 software was used for statistical analysis of the data. Results: The three genotypes A/A, A/G and G/G PLCE1 gene rs2274223 was 31, 16 and 4 cases, accounting for 60.8%, 31.4%, 0.08% respectively. The difference of three genotypes (AA/GA/GG) proportion between negative and positive family history of patients was statistically significant, ${\chi}^2=6.213$, p=0.045. There was no statistically significant relationship between PLCE1 gene rs2274223 polymorphism and smoking, drinking, ${\chi}^2=0.119$, p=0.998, and ${\chi}^2=1.727$, p=0.786. There was no linkage of the three rs2274223 PLCE1 gene genotypes (AA/GA/GG) proportion with eating fried, pickled, hot, mildew, overnight, smoked, excitant food, eat speed, salt taste or not (p>0.05). or with living environment pollution and nine risk factors of occupational exposure (p>0.05). There was no statistically significant difference in TS scores between different genotype of rs2274223 PLCE1 gene. Conclusions: The PLCE1 rs2274223 polymorphism has a relationship with family history of esophageal cancer, but does not have any significant association with age, gender, smoking, alcohol drinking, food hygiene, eating habits, living around the environment and occupation in cases.

• Tuberculosis and Respiratory Diseases
• /
• 제62권1호
• /
• pp.27-32
• /
• 2007

연구배경: 폐암환자를 대상으로 의무기록에서 흡연 습관의 정확성을 평가하고, 이에 영향을 미치는 요인들을 분석하고자 한다. 연구방법: 폐암을 진단받고 입원한 225예 환자를 대상으로 흡연 습관에 대한 일대일 면접 설문조사와 의무기록 사이의 일치도를 평가하였다. 의무기록의 흡연정보 누락과 두 자료원의 불일치에 기여하는 요인을 평가하기 위하여 다변량 로지스틱 회귀분석을 시행하였다. 결 과: 흡연 습관은 전반적으로 증등도의 일치도 (${\kappa}=0.60$)를 보였으며, 과거 흡연의 일치도(${\kappa}=0.49$)가 가장 낮았다. 의무기록의 흡연정보 누락률은 18.2%였으며, 세포형에 따라 유의한 차이를 보여, 편평상피세포암에 비하여 선암 환자에서의 누락률이 3배 높았다. 두 자료원 사이의 불일치는 65세 미만에 비해 65세 이상에서 3배 많았다. 결 론: 의무기록의 흡연 정보는 중등도의 정확성을 가진다. 임상 시험에서 흡연 습관에 대한 자료원으로 의무기록 정보를 이용하는데 세심한 주의가 필요하다고 판단한다.

• 한국산업보건학회지
• /
• 제16권4호
• /
• pp.413-427
• /
• 2006

It is necessary to study and develop guidelines for providing comfort and health indoor air quality for office workers since air-tight envelope system of current office building may cause poor indoor air quality. The purpose of this study is to propose guideline for volatile organic compounds in office base on the field study, human health risk assessment and cost-benefit analysis. The field study was conducted to survey the concentrations of volatile organic compounds in indoor air of 69 offices from June to September, 2005 in Seoul and Gyeonggi-do. The rate of excess to guideline of volatile organic compounds in indoor air of new apartment on the Ministry of Environment in Korea(MOE) was surveyed 37.6% for benzene, 6.8% for toluene, and 1.5% for ethylbenzene. As the result of human health risk assessment, mean cancer risk did not exceed 10-6 which is guideline of US.EPA. Also, total hazard index did not exceed 1 which is guideline of US.EPA. Through the cost-benefit analysis of angle on the social-economics to verify the necessary to establish the standards of volatile organic compounds for improvement and development of indoor air quality in office, the present value of benefit was higher than the present value of cost. With the above considerations in mind, it is suggested that the field study for indoor air quality in offices should be expanded and human health risk assessment and cost-benefit analysis be performed th offer scientific data for decision-making of policy for improvement and management of indoor air quality in office.

• 한국직업건강간호학회지
• /
• 제27권1호
• /
• pp.25-35
• /
• 2018

Purpose: The purpose of this study was to figure out emotional labor, healthy lifestyle, needs for health services of flight attendants and the relationships among needs for health services according to various characteristics of flight attendants. Methods: The participants of this study were 140 flight attendants who work on major and low cost airlines. Data were collected through a questionnaire from 2017 .Jan.~2017. Feb. Data were subsequently analyzed using the SPSS 21 Program. Results: The score of emotional labor was 3.76 surface acting was 3.75 and deep acting was 3.77. The average of healthy lifestyle was 2.41, and the highest was 3.13 of personal relationship and the lowest was 1.91 of eating habits. There is a positive correlation between emotional labor-deep acting and healthy lifestyle. Flight attendants demand health services for physical exercise, stress and emotional labor management, healthy eating habits, emergency treatment, prevention of fatigue, cancer screening, sexual harassment prevention, sex education and etc. Conclusion: These results show that flight attendants need to various interventions for improving healthy lifestyle and reducing emotional labor. It is necessary to develop customized health promotion program suited to their job and general characteristics.

• Journal of the Korean Data and Information Science Society
• /
• 제26권1호
• /
• pp.101-109
• /
• 2015

행정구역상 읍/면/동 단위의 소지역 (small area)별로 질병위험의 차이에 대한 분석을 위해, 2005년 기준 서울 행정동을 기준으로 2005년부터 2008년까지 질병, 사고, 암 사망자료에 대한 표준화 사망률 (SMR; standardized mortality rate)을 고려하였다. 소지역 단위로 질병사망률을 직접 추정하는 것은 소지역 내 표본수가 작아, 개발 소지역 단위에서의 직접 계산된 SMR은 그 추정치의 정도 (precision) 확보가 어려운 문제점이 발생한다. 따라서, 본 연구에서는 각 소지역간 효과 추정을 위해 공간적 상관성 (spatial correlation)을 가지는 다단계 일반화 선형모형 (HGLM; hierarchical generalized linear models)을 고려하였다. 이를 통해, 서울지역 동별 주요 사망원인에 따른 공변량의 효과 및 추정된 SMR을 근거로 질병지도 결과를 제시하였다.