• 재활치료과학
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• 제8권2호
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• pp.43-53
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• 2019

목적 : 본 연구의 목적은 Upper extremity performance test for elderly (TEMPA)의 한국 노인 표준치를 제시하고, 수집된 자료를 바탕으로 한국 노인의 연령별, 성별 손 기능의 특성과 근력의 차이를 알아보는 것이다. 연구방법 : 연구에 참여한 대상자는 60세 이상의 손 기능에 장애가 없는 노인 103명이었다. 손 기능의 특성을 알아보기 위하여 모든 대상자에게 TEMPA 평가를 시행하였고, Jarmar dynamometer, pinch gauge를 사용하여 손과 손가락 근력을 평가하였다. 결과 : 나이가 증가함에 따라 수행 속도와 소 근육의 움직임의 질이 유의미하게 감소하였다. 남성 노인의 수행 속도와 소 근육 움직임의 질이 여성 노인보다 더 높게 유지 되었다. 노인의 손과 손가락의 근력 또한 연령이 증가함에 따라 유의미하게 감소하였다. 결론 : 작업치료사는 노인의 손 기능과 근력 감소에 대한 관심을 가지고 그 기능 수준을 유지하기 위한 중재를 제공하는 것이 필요할 것이다. 본 연구를 통해 TEMPA의 한국 노인 표준치가 확립되었다. 이 자료가 임상적 평가 및 근거 기반의 연구에 있어 유용하게 쓰이기를 기대한다.

• Asian-Australasian Journal of Animal Sciences
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• 제32권8호
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• pp.1145-1152
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• 2019

Objective: Mulberry (Morus alba L.) is a cultivated shrub grown widely in the sub-tropical and tropical areas. It has been shown that mulberry leaf contains high levels of protein while having polyphenols as phytonutrients. Therefore, it is important to conduct an experiment to assess potential toxic level from mulberry on behavior, blood hematological and coagulation parameter using Sprague-Dawley (SD) rats. Methods: Both male and female SD rats were given an intragastric administration of respective treatments of mulberry leaf intakes (control, low and high levels). Parameters of feed intake, hematological and coagulation of blood parameters, as well as liveweight changes were taken during the 7 d of adaptation, 28 d of treatment exposure, and 14 d of recovery periods, respectively. All treatment data were statistically analyzed using analysis of variance of SPSS17.0 for Windows Statistical Software following the Randomized complete block design with sex as a block. Results: Most of the parameters of the physical symptoms of the SD rats, were not significantly different (p>0.05) when compared with that of the control group. Those which remain unchanged in each dose group were, body weight (BW) gain, feed intake, the hematology and coagulation indexes. Although, there were a few individual indicators that were abnormal, but the overall physiological appearance of the rats were normal. Conclusion: Results under this experiment revealed that most hematological and coagulation parameters of the SD rats in both male and female were normal, although the weight gain of female rats in high-dose group was significantly reduced than those of the male rats. Under this study, the use of mulberry leaf up to 2 g/kg BW did not result in abnormal phenomenon in the SD rats. These findings would offer useful information for further in vivo feeding trials in animals to extensively use of mulberry leaf to improve animal production, particularly in P.R. China.

• Asian-Australasian Journal of Animal Sciences
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• 제32권5호
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• pp.711-720
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• 2019

Objective: This study was conducted to assess the effect of potassium humate and enzymes (Xylanase+Amylase+Protease) inclusion in diets on carcass characteristics, meat quality and fatty acid profiles of broilers fed canola-based diets. Methods: Two hundred and twenty broilers randomly allotted to 5 dietary treatments: the control (commercial broiler diet); CM (17.5% canola meal inclusion); CMEnz (17.5% CM inclusion+0.3 g/kg Axtra XAP); CMPh (17.5% CM inclusion+1.5% Potassium Humate, PH); and CMEnzPh (17.5% CM inclusion+1.5% PH+0.3 g/kg Axtra XAP) were slaughtered at day 42 for assessment of carcass and meat quality parameters. Results: Diet had no effect on carcass traits apart from breast muscle weight and breast muscle index. The highest breast muscle weight was observed in broilers fed CMEnz ($487.6{\pm}17.5g$) followed by those fed the control diet ($474.37{\pm}17.5g$). Diet also had no significant dietary effect on pH, temperature, drip loss and shear force values of the breast muscle. However, diet significantly affected meat colour and water-holding capacity. Broilers in the control and CMPh groups ($52.94{\pm}0.67$ and $52.91{\pm}0.67$) had the highest (p<0.05) values for lightness ($L^*$), whilst those fed CMEnzPh had the lowest value ($47.94{\pm}0.67$). In contrast, CM group had the lowest (p<0.05) value for redness ($a^*$) with CMEnzPh group having the highest values. The proportion of polyunsaturated fatty acids (PUFAs), n-6 and n-3 fatty acids and the PUFA/saturated fatty acid ratio were increased in CM-based diets containing enzymes and humic acid. Conclusion: It can, therefore, be concluded that CM can be included in broiler diets in the presence of enzymes and humic acid with positive effects on meat quality and important fatty acids that are beneficial to the health of consumers.

• 정보교육학회논문지
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• 제23권2호
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• pp.131-139
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• 2019

2019년부터 소프트웨어 교육은 모든 초등학생들이 배워야 하는 필수과목이 되었다. 하지만 아직 어떤 식으로 수업을 진행해야 할지에 대해서는 많은 교사들이 낯설어하고 있다. 이에 이 논문에서는 소프트웨어 교육의 핵심이 되는 컴퓨팅 사고력 중 데이터 수집, 분석, 표현 수업에 도움이 되고자 각각의 의미, 세부역량과 성취기준을 제시하고 예시수업을 통해 적용 가능성을 제시하였다. 논문의 전체 과정을 요약하면 다음과 같다. 첫째, 기존의 연구들에서 데이터 관련 역량의 의미, 세부역량 및 성취기준에 관한 연구들을 정리하고 이것을 바탕으로 하여 예비조사를 진행하였다. 예비조사에서는 FGI와 폐쇄형 질문을 동시에 진행하였으며 이를 통하여 전문가들의 검토의견을 반영한 본 조사의 설문 문항을 작성하였다. 둘째, 위의 결과로 만들어진 설문문항을 컴퓨터교육 전공 박사, 박사과정, 소프트웨어교육 담당 교사 및 소프트웨어교육 종사자를 대상으로 하여 타당도, 안정도, 신뢰도를 검증받았다. 셋째, 그 결과 개발된 세부역량과 성취기준 중 '수집방법 선택-문제 상황에 따라 수집 방법을 선택할 수 있다', '데이터의 의미 탐색-분석된 데이터들이 어떤 의미를 갖는지 안다.', '다양한 표현방법 활용-다양한 표현 도구를 사용한다.'를 수업목표로 하여 다섯 차시의 수업을 개발하여 적용하였으며 이 때 교육, 수업, 평가의 일체화를 위해 백워드 2.0 설계모형을 활용하였다. 그 결과 최종적으로 데이터 수집, 분석, 표현의 세부역량과 성취기준을 제시하였다. 이는 초등학교에서 데이터 관련 수업을 계획함에 있어 어떠한 방향으로 수업을 하면 좋을 지에 대한 구체적이고 명확한 기준을 세울 때 도움이 될 수 있을 것이다.

• Journal of Gynecologic Oncology
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• 제29권6호
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• pp.83.1-83.10
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• 2018

Objective: We aimed to propose a set of quality indicators (QIs) based on the clinical guidelines for cervical cancer treatment published by The Japan Society of Gynecologic Oncology, and to assess adherence to standard-of-care as an index of the quality of care for cervical cancer in Japan. Methods: A panel of clinical experts devised the QIs using a modified Delphi method. Adherence to each QI was evaluated using data from a hospital-based cancer registry of patients diagnosed in 2013, and linked with insurance claims data, between October 1, 2012, and December 31, 2014. All patients who received first-line treatment at the participating facility were included. The QI scores were communicated to participating hospitals, and additional data about the reasons for non-adherence were collected. Results: In total, 297 hospitals participated, and the care provided to 15,163 cervical cancer patients was examined using 10 measurable QIs. The adherence rate ranged from 50.0% for 'cystoscope or proctoscope for stage IVA' to 98.8% for 'chemotherapy using platinum for stage IVB'. Despite the variation in care, hospitals reported clinically valid reasons for more than half of the non-adherent cases. Clinically valid reasons accounted for 75%, 90.9%, 73.4%, 44.5%, and 88.1% of presented non-adherent cases respectively. Conclusion: Our study revealed variations in pattern of care as well as an adherence to standards-of-care across Japan. Further assessment of the causes of variation and non-adherence can help identify areas where improvements are needed in patient care.

• International Journal of Computer Science & Network Security
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• 제21권5호
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• pp.73-83
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• 2021

The information space, the main components of which are information resources, means of information interaction, and information infrastructure, is a sphere of modern social life in which information communications play a leading role. The objective process is the gradual but stable entry of the national information space into the European and world information sphere, in the context of which there is a legitimate question of its protection as one of the components of the national security of Ukraine. However, the implementation of this issue in practice immediately faces the need to respect the rights and fundamental freedoms guaranteed by international regulations and the Constitution of Ukraine, especially in the field of cybersecurity. The peculiarity of the modern economy is related to its informational nature, which affects the sharp increase in cyber incidents in the field of information security, which is widespread and threatening and affects a wide range of private, corporate, and public interests. The problem of forming an effective information security system is exacerbated by the spread of cybercrime as a leading threat to information security both in Ukraine and around the world. The purpose of this study is to analyze the state of cybersecurity and on this basis to identify new areas of the fight against cybercrime in Ukraine. Methods: the study is based on an extensive regulatory framework, which primarily consists of regulatory acts of Ukraine. The main methods were inductions and deductions, generalizations, statistical, comparative, and system-structural analysis, grouping, descriptive statistics, interstate comparisons, and graphical methods. Results. It is noted that a very important component of Ukraine's national security is the concept of "information terrorism", which includes cyberterrorism and media terrorism that will require its introduction into the law. An assessment of the state of cybersecurity in Ukraine is given. Based on the trend analysis, further growth of cybercrimes was predicted, and ABC analysis showed the existence of problems in the field of security of payment systems. Insufficient accounting of cybercrime and the absence in the current legislation of all relevant components of cybersecurity does not allow the definition of a holistic system of counteraction. Therefore, the proposed new legal norms in the field of information security take into account modern research in the field of promising areas of information technology development and the latest algorithms for creating media content.

• 재활치료과학
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• 제10권2호
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• pp.7-22
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• 2021

목적 : 본 연구의 목적은 뇌졸중 환자의 인지기능 회복에 대한 경두개 직류자극(tDCS)의 효과를 살펴본 연구를 분석하기 위함이다. 연구방법 : 2009년부터 2019년까지 국내외 학술지에 게재된 논문들을 NDSL, RISS, PubMed, CINAHL을 통해 검색하였다. 선정기준과 배제기준을 통해 총 11개의 실험연구 논문이 선정되었다. 이를 질적평가를 시행하고, 이 중 7편의 논문에서 9개의 결과값에 대해 메타분석을 실시하였다. 결과 : 메타 분석을 실시한 결과 효과크기는 attention 0.725, memory 0.796으로 모두 '보통 효과크기'를 보였다. 두 영역 모두 통계적으로 유의한 변화가 있던 것으로 분석되었다(p<0.05) 결론 : 본 연구 결과를 통하여 인지기능이 제한된 뇌졸중 환자에게 tDCS는 효과가 있음을 알 수 있었다. 또한, tDCS 적용법이 연구 간 서로 상이함을 알게 되었으며 이에 따라 정형화된 tDCS 프로토콜과 전문가 양성이 필요할 것으로 보인다.

• 재활치료과학
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• 제10권2호
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• pp.37-51
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• 2021

목적 : 본 연구는 주로 침흘림을 보이는 뇌성마비 아동에게 비침습적인 치료적 중재와 침흘림 측정방법의 경향 분석 등에 대한 국외 문헌들을 중심으로 종합적으로 분석하고자 하였다. 연구방법 : 본 연구는 최근 15년 간(2005-2019) 국외 논문을 검색하여 총 265편의 논문이 검색되었다. 1차 제목 및 초록을 중심으로 44편의 논문이 선정되었고, 2차 원문 검색을 통해 10편의 논문이 최종적으로 선정되었다. 결과 : 선정된 논문의 PEDro Scale은 평균 6점으로 높은 편이었다. 전반적인 동향을 분석한 결과 연구대상자는 뇌성마비가 주를 이루었고, 행동수정에 비해 구강감각운동의 치료적 중재가 최근에 활발하게 연구되고 있었다. 행동수정과 구강감각운동 중재방법은 대상자의 나이, 인지수준, 대상자 수, 연구설계, 치료시간과 기간에서 차이가 있음을 확인하였다. 침흘림 측정방법은 빈도와 심각성을 동시에 확인하는 연구가 주를 이루는 것으로 나타났다. 결론 : 본 연구에서는 침흘림을 보이는 뇌성마비 아동에게 실시한 비침습적인 중재 중 대표적인 행동수정과 구강감각운동 중재에 대해서 분석하였고, 이러한 자료를 통해 행동수정과 구강감각운동치료를 통한 침흘림 프로그램 계획 시 적절한 치료적 중재방법을 선택하는데 도움이 될 수 있는 정보제공 및 근거를 마련하였다.

• Animal Bioscience
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• 제34권1호
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• pp.26-35
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• 2021

Objective: This study was conducted to assess the level of pregnancy-associated glycoprotein (PAG) in whole and skim milk samples, and its suitability for early pregnancy diagnosis in goats. Methods: A two-step sandwich enzyme-linked immunosorbent assay (ELISA) system for estimation of milk PAG was developed and validated, which employed caprine-PAG specific polyclonal antisera. Whole and skim milk samples (n = 210 each) from fifteen multiparous goats were collected on alternate days from d 10 to d 30, and thereafter weekly till d 51 post-mating. PAG levels in milk samples were estimated by ELISA and the pregnancies were confirmed at d40 post-mating by transrectal ultrasonography (TRUS). Results: The level of PAG in whole and skim milk samples of both pregnant and nonpregnant goats remained below the threshold values until d 24 after mating. Thereafter, PAG concentration in whole and skim milk increased steadily in pregnant goats, whereas it continued below the threshold in non-pregnant does. The PAG profiles in whole and skim milk of pregnant goats were almost similar and exhibited strong positive relationship (r = 0.891; p<0.001). Day 26 post-mating was identified as the first time-point for significantly (p<0.05) higher milk PAG concentration in pregnant goats than to non-pregnant goats. When compared to TRUS examination for pregnancy diagnosis, the accuracy and specificity of PAG ELISA using whole and skim milk samples were 94.5% and 95.4%; and 95.3% and 100%, respectively. The high values of area-under-curve (0.904 [whole milk] and 0.922 [skim milk]), demonstrate outstanding discrimination ability of the milk assays. Among the sampling dates chosen, d 37 post-mating was identified as the best suitable time point for collection of milk samples to detect pregnancy in goats. Conclusion: The PAG concentration in whole and skim milk of goats collected between days 26 and 51 post-breeding can be used for the accurate prediction of pregnancy and may be useful for assisting management decisions in goat flocks.

• 대한후두음성언어의학회지
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• 제31권2호
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• pp.71-77
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• 2020

Background and Objectives OperaVOXTM (Oxford Wave Research Ltd.) is a portable voice analysis software package designed for use with iOS devices. As a relatively cheap, portable and easily accessible form of acoustic analysis, OperaVOXTM may be more clinically useful than laboratory-based software in many situations. The aim of this study was to evaluate the agreement between OperaVOXTM and Multi-Dimensional Voice Program (MDVP; Computerized Speech Lab) to assess voice quality before and after laryngeal microsurgery in patient with vocal polyp. Materials and Method Twenty patients who had undergone laryngeal microsurgery for vocal polyp were enrolled in this study. Preoperative and postoperative voices were assessed by acoustic analysis using MDVP and OperaVOXTM. A five-seconds recording of vowel /a/ was used to measure fundamental frequency (F0), jitter, shimmer and noise-to-harmonic ratio (NHR). Results Several acoustic parameters of MDVP and OperaVOXTM related to short-term variability showed significant improvement. While pre-operative value of F0, jitter, shimmer, NHR was 155.75 Hz (male: 125.37 Hz, female: 183.37 Hz), 2.20%, 6.28%, 0.16, post-operative values of these parameter was 164.34 Hz (male: 129.42 Hz, female: 199.26 Hz), 2.15%, 5.18%, 0.14 Hz in MDVP. While pre-operative value of F0, jitter, shimmer, NHR was 168.26 Hz (male: 135.16 Hz, female: 201.37 Hz), 2.27%, 6.95%, 0.26, post-operative values of these parameters was 162.72 Hz (male: 128.267 Hz, female: 197.18 Hz), 1.71%, 5.36%, 0.20 in OperaVOXTM. There was high intersoftware agreement for F0, jitter, shimmer with intraclass correlation coefficient. Conclusion Our results showed that the short-term variability of acoustic parameters in both MDVP and OperaVOXTM were useful for the objective assessment of voice quality in patients who received laryngeal microsurgery. OperaVOXTM is comparable to MDVP and has high intersoftware reliability with MDVP in measuring the F0, jitter, and shimmer