• 대한한방내과학회지
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• 제10권1호
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• pp.53-64
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• 1989

In an attempt to investigate the current of clinical researches on spleen yang or vital energy deficiency syndrome, the results were as follows. 1. It is possible to occure spleen deficiency syndrome which come from genetic factor. 2. The absorption disturbance in spleen deficiency syndrome can be likely caused by gastrointestinal mucosa injury, disorder of vagus nerve funtion and impairment of excretion of exocrine gland in pancreas. 3. Owing to the failure of tansporting and converting funtion of spleen, minerals, hematogenic substance and nutritional substance are scanty and then imbalanced metabolism state which heat production is decreasing is appeared. 4. By the failure of vital energy and blood growth, decreasement of $O_2$ transportation ability of RBC, disoder of blood coagulation, immune system disturbance which humoral immunity is enhanced and cellular immunity is decreased, are noted. 5. While there is not still an attemt to study the spleen deficiency sydrome in muscle disease or disease of four extremities, but it is likely suggested that spleen-stomach supplyment thereapy is very excellent effect on muscle disease and disease of four extremities.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제22권4호
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• pp.407-412
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• 2019

Excessive weight gain in children diagnosed with celiac disease (CD) is becoming more common. We describe 2 siblings (9-year and 6 months-old female and 6-year and 9 months-old male) with obesity showing attenuated gastrointestinal and atypical symptoms in which CD was diagnosed in the absence of a known family history of CD. After children's diagnosis, CD in their parents was also investigated. It was detected in their father affected by overweight. The presentation of patients with CD has changed. While patients with overweight and obesity commonly have symptoms such as abdominal pain, reflux, headache, and constipation due to lifestyle factors, CD should also be considered in patients with or without a family history of CD. Careful nutritional status assessment and follow-up monitoring after the diagnosis of CD are mandatory, especially in subjects who are already overweight at the presentation of this disease.

• Journal of Nutrition and Health
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• 제51권3호
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• pp.215-227
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• 2018

본 연구는 심혈관질환으로 심장수술을 받은 환자 15명 대상에게서 12주 동안 한식으로 식이조절 교육을 통해 한식 섭취가 증가하고 이를 통해 CVD 위험인자 및 약물 투여량의 변화, 영양소 섭취량에 미치는 영향과 관련성에 대한 분석 결과는 다음과 같았다. 1. 대상자의 평균 연령은 $60.7{\pm}2.5$세로 최근 3년 이내에 심혈관질환 수술을 받고 지속적으로 심혈관질환 약물을 복용하고 있는 환자였다. 2. 대상자의 한식 식이조절 교육 순응도 점수는 교육 전 $35.8{\pm}0.9$점에서 교육 후 $43.0{\pm}1.2$점으로 유의적으로 증가하였는데 (p < 0.001), 이는 한식 섭취를 적극적으로 실천하였음을 시사한다. 3. 대상자의 비만지표인 체중 및 체질량지수는 교육 후, 감소 경향을 보였으며 허리둘레 (p = 0.002) 및 허리 엉덩이둘레비인 WHR (p < 0.001)는 유의적으로 감소하였다. 4. 대상자들의 혈당조절 지표인 HbA1c는 교육 전 $7.3{\pm}1.0%$에서 교육 후 $7.0{\pm}1.1%$로 유의적으로 감소하였다 (p < 0.05). 5. 대상자들의 항고혈압제약물의 투여량 변화는 교육 전 2.1개에서 교육 후 1.7개로 줄었음에도 불구하고 혈압은 정상범위에서 안정적으로 유지되었음을 확인하였다. 항당뇨병 약제 복용량은 유의적인 변화는 보이지 않았으나, 안정된 상태로 적절한 혈당을 유지함과 동시에 혈당 조절 지표인 당화혈색소가 감소함을 확인하였는데 이는 혈당조절이 개선되고 있는 것으로 나타났다. 6. 한식 식사유형인 음식군별 섭취량의 변화는 교육 전에 비해 교육동안에 전곡류로 지은 밥 중심의 식사량이 유의적으로 증가하였고 (p = 0.018), 채소류인 나물류 (p = 0.007), 김치 (p < 0.001) 및 전통 콩발효 양념 (p < 0.001) 등의 섭취가 유의적으로 증가하였다. 7. 대상자들의 영양소 섭취는 일일 에너지 섭취량은 변화가 없었으나 교육 전보다 교육 동안에 동물성급원식품에서 유래한 동물성 단백질과 지질 및 콜레스테롤의 섭취량은 유의적으로 감소 (p < 0.05)한 반면 나트륨 (p = 0.019), 칼륨 (p = 0.028), 식이섬유 (p < 0.050), 비타민 A (p = 0.028), 비타민 C (p = 0.010) 및 엽산 (p < 0.001)의 섭취는 유의적으로 증가하였다. 이상의 결과를 종합해 보면, 적극적인 한식 섭취를 권장하고 장려하는 식이조절교육 중재는 심혈관질환 수술을 받은 환자에게서 영양소 섭취와 심혈관계 위험인자인 비만지표, 혈당조절 지표에 대하여 긍정적인 영향을 주었다. 본 연구의 한계로는 교육에 참여한 대상자가 15명으로 다소 적었으며 단기 교육에 의한 전후 비교 평가에 의한 것으로 그 결과를 일반화하기에는 제한점이 있다. 따라서 향후 연구 장기간의 교육과 대조군이 있는 비교 연구가 필요할 것으로 사료된다.

• 동아시아식생활학회지
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• 제6권2호
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• pp.273-276
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• 1996

The Traditional Food mean the plants which bear nutritional function and of which purpose is keeping health. However, when it is used for protection or cure of disease, we can call them medicinal substances. Therefore medicine and eating are ultimately same. Because of this point of a dietetic material medical foodstuff, if we obey Mother Nature and make a balanced diet, everyone will be able to enjoy a long life with keeping health.

• Advances in Traditional Medicine
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• 제2권1호
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• pp.17-27
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• 2002

Obesity is a serious medical disorder because it can cause a myriad of health problems, such as heart disease, hypertension, and adult-onset diabetes. While conventional medical treatment for obesity has limitations, there is enormous public enthusiasm for complementary and alternative treatments of obesity. This article reviews currently commonly used complementary and alternative therapies for obesity, such as medicinal herbs, nutritional supplements and acupuncture. Beneficial effects and possible adverse effects associated with these treatment are discussed.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제12권sup1호
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• pp.12-26
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• 2009

Parenteral nutrition (PN) is effective and relatively safe method providing nutrients to patients with a nonfunctioning or insufficiently functioning gastrointestinal tract via peripheral or central vein. In last several decades, useful steps have been taken in the understanding of nutritional needs, physiological changes and complications of intravenously fed patients. PN includes amino acids, glucose, lipids, electrolytes, vitamins, iron, minerals and trace elements, and must be based on individual circumstances such as patient's age, health status and disease. The purpose of this review is to introduce overall components and recent updates of parenteral nutrition.

• 한국수의병리학회:학술대회논문집
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• 한국수의병리학회 2003년도 추계학술대회초록집
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• pp.35-38
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• 2003

The parathyroid gland is probably the simplest endocrine organ in the body. The only cells of clinical significance are the parathyroid or chief cells. The primary signal that these cells listen to is calcium. Primary hyperparathyroidism is due to a parathyroid adenoma. The most common cause of hypercalcemia in veterinary medicine is hypercalcemia of malignancy associated with variety of neoplasms. Secondary hyperparathyroidism is due to a disease process, most commonly associated with renal and nutritional hyperparathyroidism. Primary and secondary hyperparathyroidism are markedly different in their clinical, laboratory, and pathogenic mechanism.

• Journal of Plant Biotechnology
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• 제37권1호
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• pp.67-71
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• 2010

Output traits centered on improved plant-based products will find their way to consumers in such ways as nutritionally enhanced foods, therapeutic proteins for disease treatment and vaccines, bio-industrial products, modified oil quality and biofuels. Significant progress in biotechnology has occurred over the last several decades. The importance of output traits development and production using biotechnology will impact not only agribusiness, but also pharmaceutical and food industries. The objective of this paper is to review briefly the current status of output traits development in crop plants using nutrients and pharmaceuticals as examples.

• 대한지역사회영양학회지
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• 제12권4호
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• pp.396-404
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• 2007

Increased oxidative stress contributes to the progression of atherosclerosis. We measured serum antioxidant mineral concentrations, capacities of serum antioxidant enzymes and fasting lipid profile in 97 male patients with coronary artery disease (CAD) and 21 male controls. Nutrient intake was assessed by the semi-quantitative food frequency method. CAD patients were divided into single-vessel disease (SVD, n=66) and multi-vessel disease (MVD, n = 31) groups on the coronary angiography. The ratio of serum LDL- to HDL-cholesterol elevated with an increasing number of diseased vessels compared to the control (control < SVD < MVD, p < 0.05). Patients with SVD and MVD had higher levels of serum lipoprotein (a) than the control (p < 0.05). The mean intake of carbohydrate, protein and cholesterol was higher in MVD patients and the intakes of vitamins C and E were lower in MVD and SVD patients than in the control (p < 0.05). Serum copper (Cu) and zinc (Zn) levels were higher in MVD and SVD patients than in the control (Cu: control $75.8{\pm}5.07$, SVD $99.2{\pm}2.90$, MVD $100.1{\pm}2.32{\mu}g/dL$, p<0.01; Zn: $76.8{\pm}5.36$, $119.0{\pm}5.95$, $129.1{\pm}2.70{\mu}g/dL$, p < 0.01). And the ratio of Zn to Cu was higher in SVD and MVD patients than in the control (control $0.78{\pm}0.06$, SVD $0.88{\pm}0.05$, MVD $0.99{\pm}0.04$, P < 0.05). The activity of glutathione peroxidase (GSH-Px) was lower in MVD than in SVD and the control (control $35.13{\pm}1.34$, SVD $35.30{\pm}1.01$, MVD $31.00{\pm}1.04 U/mg$ protein, p < 0.05). The ratio of the activities of superoxide dismutase (SOD) to GSH-Px was higher in MVD than in control and SVD (p < 0.05). In groups with CAD, serum Cu and Zn concentrations and their ratio were changed compared to the control. GSH-Px activity was decreased and the ratio of SOD to GSH-Px was increased in the patients with MVD. The balances between the activities of SOD and GSH-Px should also be considered a risk factor in CAD patients.

• 대한지역사회영양학회지
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• 제3권1호
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• pp.76-93
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• 1998

Three hundred sixty-two(male 131, female 231) elderly aged over 65 in Chungb- uk area were interviewed to determine the disease states and drug usage patterns. The prebalence of disease was 78% and women reported more chronic diseases(83%) than men(71%). Elderly who live with spouse and have an occupation have a lower rate of disease. Average number of diseases of the elderly was $1.8\pm{1.1}$, and women$(2.1\pm{1.3)}$ have significantly higher average number of diseases than that of men$(1.4\pm{0.7)}$. Also the elderly in urban areas$(2.1\pm{1.4)}$ have significantly higher number of diseases than that of the elderly in rural areas$(1.6\pm{0.9)}$. Arthritis, hypertension, cardiovascular and gastric diseases were the most frequently listed chronic diseases in order for both men and women. Anemia and fracture of bone were relatively higher in women than in men. Particularly, the arthritis of the urban elderly have a rate of 1.5 times higher than that of the rural elderly. Fifty-two percent of the elderly were currently using drugs ; among drug users 71.2% used prescription drugs and 20.5% used nonprescription drugs. The average number taken per person was 2.1$\pm$1.4 and there was no sex or age difference. However, the elderly in rural areas $(2.7\pm{1.7)}$ consumed a significantly higher number of drugs than those in urban areas$(1.7\pm{0.7)}$. The average number of prescripti- on drugs taken was 2.0$\pm$1.4 while the average of nonprescription drugs taken was $(1.3\pm{0.6)}$. Analgesics and antihypertensive drugs were most commonly used. Vitamin and analgesics were the most frequently used self-prescribed drugs. It was noted that potential adverse drug interaction by concominant drug consumption for arthritis and antihypensive drug, abuse of digestants and antiacid without treatment of the underlying disease, and misuse of quick-acting bowel medications were problematic for the elderly. In addition drugs used for the elderly have some adverse effect on the digestive system. The types and composition of drugs used by the elderly were identified and presented. Medication compliance was poor and 13.5% reported adverse reactions such as edema, heartburn, nausea, and difficulty with eating. Seventeen percent of the elderly obtained drugs arranged by those other than medical staff. Also, even among those elderly who obtained drugs prescribed by a doctor, 69.1% of subjects had not receive instruction about potential adverse reactions. These results suggest that nutritional problems related to drug usage might exist and so dietitians, either individually or as members of health teams, need to have a better understanding of drug-nutrient interaction and closer supervision, and drug information/education service should therefore be provided to prevent or minimize adverse drug reaction in elderly users of medication.