• Journal of the Korean Home Economics Association
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• v.25 no.1
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• pp.83-92
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• 1987

Information on the planning of the housing unit for three generation family is required for developing nuclear families and increasing elderly person. This study deal with the life style, it's characteristics and housing needs of the elderly who lived with other two generations. Specifically, this study attempted to find the basic information of the detailed planning and the establishment of criteria of the housing unit for three generation family. The results of this study were as follows. 1. Planning of the housng unit for three generation family, it had to be taken over residency areas for elderly especially for keeping privacy each other. 2. It was necessary the criteria of housing standards for eldery based on their housing characteristics. 3. Considering the psychological characterstics and life style of the elderly, it should be suggest that they could live easily with their next generation in the samecommunity. Also, the public policy should take over the housing unit for three generation family.

• Research in Community and Public Health Nursing
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• v.12 no.2
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• pp.406-416
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• 2001

This study is performed to confirm the influencing factors of family health protection behaviors using the variables included in Pender's Family Promotion Model. 1. The subjects are 110 families in preschooler family developmental stage, respondents are children's mother or father. These families are almost all nuclear types(95%), function of families is healthy as much as 8.0 the mean FAPGAR score. The prevalence rate of family members' illness was 14.7% these last 3 months, and 21.1 % of families responded suffered from injury for last 2 years. 2. The practice rate of injury prevention behavior is below a half in supervision and modifying of their home and residential environments, especially controlling through collaborative community power. The more familiar function score is the better practicing rates of injury prevention behaviors. 3. The injury prevention behaviors correlate to family size, health status of family member, and children's congenital defects with statistical significance. Families' economic condition correlates also significantly to family health status, cognition of benefits of injury prevention, cognition of the importance of community collecting power. And the recognition of the benefits of injury prevention correlates the adaptive health concept, family norms about injury prevention, economic status. 4. Considering family health promotion model. the general influencing factor is only affected to family protective behavior, and other paths don't affect to family's behaviors. In simple regression, the family protective behavior model explains 27.8%(P=0.05), significant factors are family function status, family size, chronic illness of family members', mother's education level. father's age. 5. To define of familiar preventive behavior as a unit is very important, but it has the limitation to solve the difficulties of family studies going with the operationalized difficulties of health promotion concept.

• Journal of the Korean Home Economics Association
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• v.49 no.5
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• pp.97-115
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• 2011

The focus of this study was on the self-differentiation level of families with an elderly member suffering from dementia. Based on 340 questionnaires collected in Seoul and Gyeonggi, the study intended to explain the adaptation issues of those families. The variables of interest, which might be related to the self-differentiation, were chronic anxiety(i.e. stress), the family function, psychosomatic symptoms and the family's adaptation to care-giving. As a result of analyzing the effects of the variables potentially related to the self-differentiation level of care-giving families, the findings from this study were as follow. With decreasing self-differentiation level of the family caring for an elderly member suffering from dementia, the levels of stress and psychosomatic symptoms were significantly increased, but the family function and the adaptation to care-giving tended to decrease. Conversely, with increasing self-differentiation, the levels of stress and psychosomatic symptoms were significantly decreased, while the family function and adaptation to care-giving were promoted.

• Molecules and Cells
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• v.44 no.5
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• pp.342-355
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• 2021

The microphthalmia-associated transcription factor family (MiT family) proteins are evolutionarily conserved transcription factors that perform many essential biological functions. In mammals, the MiT family consists of MITF (microphthalmia-associated transcription factor or melanocyte-inducing transcription factor), TFEB (transcription factor EB), TFE3 (transcription factor E3), and TFEC (transcription factor EC). These transcriptional factors belong to the basic helix-loop-helix-leucine zipper (bHLH-LZ) transcription factor family and bind the E-box DNA motifs in the promoter regions of target genes to enhance transcription. The best studied functions of MiT proteins include lysosome biogenesis and autophagy induction. In addition, they modulate cellular metabolism, mitochondria dynamics, and various stress responses. The control of nuclear localization via phosphorylation and dephosphorylation serves as the primary regulatory mechanism for MiT family proteins, and several kinases and phosphatases have been identified to directly determine the transcriptional activities of MiT proteins. In different immune cell types, each MiT family member is shown to play distinct or redundant roles and we expect that there is far more to learn about their functions and regulatory mechanisms in host defense and inflammatory responses.

• Journal of the Korean Home Economics Association
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• v.18 no.1
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• pp.97-109
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• 1980

In Korea, the collapse of traditional Patriarchal family system has caused the weakening the patriarchal authority which represents the decrease of traditional attitude of respect for old age, influenced by the strong tendency of Materialism in ethics. The urgent problem is how to solve the conflicts of the alienation almost every old people has felt from the society and family which they belong to and how to harmonize the respect for old age who used to have had in the past. From 21st to 30th of July 1979, I explored the small village in Cheju Island with eight students which I selected on purpose that village had preserved the traditionalism. I collected the interview data form a sample of 221 persons of the village in Cheju Island. I studied this small village in Cheju Island for the intention of suggesting the ideal model of regional society which both traditional and non-formal, although the phenomena of nuclear family system and materialism and industrialism are overwhelming in ur present society. Generally people in Cheju Island are economically poor and major occupation is farming, since the industrialization proceeds very slowly and there still strongly remains the traditionalism. Alienation and dissatisfaction of old people from their family and society in Cheju island are less common in comparison to the main land. Old people in Cheju Island usually value the importance of labour. Divison of labour has been well observed in farming, and men and women in Cheju island are equally regarded in comparison to the main land. Old people are independent economically and spiritually from their offsprings and they organize the nuclear family system firmly. Also the old generation is ready to compromise with the new generation and they defy the authoritariansim.

• Journal of Families and Better Life
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• v.11 no.1
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• pp.176-190
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• 1993

This study intended to analyze the size and composition of social network and to identify their related variables in urban nuclear families. Data were collected through the questionnaires by wives living in Seoul area. The methods of statistical analysis used in the study were the frequency mean percentile and one-way ANOVA. The findings were as follows; 1) The size of social network in urban nuclear families was 10.0 in average and 2-33 in range. 2) The composition of social network were 45.5% in relatives 20.6% in neighbors. 21.8% in friends. 4,7% in coworkers, 4.1% religious group members 2.1% in associational members. and 1.4% in formal supporters. 3) The birth order of husbands was related to the size of social network. The composition of social network was influenced by SES family life cycle husband's birth order housing type residence duration age education employment religion and familism.

• Tuberculosis and Respiratory Diseases
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• v.46 no.2
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• pp.185-194
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• 1999

Background: NF-$\kappa$B is a characteristic transcriptional factor whose functional activity is determined by post-translational modification of protein and subsequent change of subcellular localization. The involvement of the NF-$\kappa$B family of the transcription factors in the control of such vital cellular functions as immune response, acute phase reaction, replication of certain viruses and development and differentiation of cells has been clearly documented in many previous studies. Several recent observations have suggested that the NF-$\kappa$B might also be involved in the carcinogenesis of some hematological and solid tumors. Investigating the possibility that members of the NF-$\kappa$B family participate in the molecular control of malignant cell transformation could provide invaluable information on both molecular pathogenesis and cancer-related gene therapy. Method: To determine the expression patterns and functional roles of NF-$\kappa$B family transcription factors in human lung cancer cell lines NCI-H792, NCI-H709, NCI-H226 and NCI-H157 were analysed by western blot, using their respective antibodies. The nuclear and the cytoplasmic fraction of protein extract of these cell lines were subsequently obtained and NF-$\kappa$B expression in each fraction was again determined by western blot analysis. The type of NF-$\kappa$B complex present in the cells was determined by immunoprecipitation. To detect the binding ability of cell-line nuclear extracts to the KB consensus oligonucleotide, electrophoretic mobility shift assay(EMSA) was performed. Results: In the cultured human lung cancer cell lines tested, transcription factors of the NF-$\kappa$B family, namely the p50 and p65 subunit were expressed and localized in the nuclear fraction of the cellular extract by western blot analysis and immunocytochemistry. Immunoprecipitation assay showed that in the cell, the p50 and p65 subunits made NF-$\kappa$B complex. Finally it was shown by Electrophoretic Mobility Shift Assay(EMSA) that nuclear extracts of lung cancer cell lines are able to bind to NF-$\kappa$B consensus DNA sequences. Conclusion: These data suggest that in human lung cancer cell lines the NF-$\kappa$B p50/p65 complex might be activated. and strengthen the hypothesis that NF-$\kappa$B family transcription factors might be involved in the carcinogenesis of human lung cancer.

• The Journal of the Korea Contents Association
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• v.22 no.5
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• pp.553-564
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• 2022

The purpose of this study is to examine the family reproduced by fishing village episode 1. (삼시세끼, three meals a day), which attempted a new type of entertainment termed an experiential real entertainment documentary, was produced in a total of nine episodes from October 2014 to March 2015. This study analyzed fishing village episode 1, which was aired in 2015 and obtained the highest ratings, using narrative analysis. The development of was consistently structured in the order of 'wake up - free time - breakfast - lunch - dinner - rest - sleep'. The character construction of the characters was created through the arrangement of a main space and a main role for each of the characters. Also, the characters were in relationships through which they became the background of each other. Therefore, in the family reproduced by , a mother without a father and a father without a mother are impossible. Despite that all the cast members were male, the subtitles constantly gave them the roles of 'housewife/wife/mother', 'father/husband/dad', and 'son', while actively blocking the image of a homosexual family. The family created as such was a family with children, a family with both mother and father, a heterosexual family, and a nuclear family. As a result, reproduced the typical modern family, normal family, and standard family.

• 대한핵의학회:학술대회논문집
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• 2000.05a
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• pp.71.1-71.1
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• 2000

• Lingua Humanitatis
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• v.1 no.2
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• pp.161-178
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• 2001

This study investigates how Korean traditional family consciousness interacts with Korean industrialization in the 1970s. In Our Children, Lee Sun depicts a family's struggle within the turmoil brought about by rapid industrialization to escape from the ranks of the working class. It is well known that one of the consequences of industrialization was the breakup of the larger family structure into nuclear families, but Lee Sun presents Korea's industrialization in the 1970s in the light of the traditional Korean family culture before the breakup. In other words, he gives us a portrayal of Gemeinschaft in Gesellschaft in his description of the extended family's struggle to overcome the day-to-day pressures of modernization and urbanization. The novel presents three generations of a traditional extended family. The eldest son is portrayed as a knife, strong and sharp. His wife has a temporary job that she hopes to give up once they own a house, which symbolizes the family's escape from the working class. The relationship among the family members reveals the core aspects of the ideology governing traditional extended families: the husband is the despotic monarch of the household, solely responsible for the family's economy; the husband is the sky and the wife the earth; and children (the more the better) are expected to lead to stability, welfare, and prosperity. One curious aspect of this family relationship as portrayed by Lee Sun is the expectation that being the eldest son, who already is or will become the patriarch of the family, is the fastest way of reaching middle-class status. And, despite a slight reversal, the novel has a happy ending wherein the family's expectations are fulfilled without much suffering. This aspect should be considered in light of the revolutionary romantic idealism of the novels of the 1930s. The lack of suffering and the easy happy ending may be attributed to the fact that Korea's industrialization came about rapidly and radically, and therefore it is likely that Lee Sun was not able fully to appreciate the full costs of industrialization. This limitation calls for a deeper investigation into the social structure and class consciousness of the 1970s, and also a study of the intertextual relationship of Our Children with other novels of the time.