• 대한가정학회지
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• 제25권1호
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• pp.83-92
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• 1987

Information on the planning of the housing unit for three generation family is required for developing nuclear families and increasing elderly person. This study deal with the life style, it's characteristics and housing needs of the elderly who lived with other two generations. Specifically, this study attempted to find the basic information of the detailed planning and the establishment of criteria of the housing unit for three generation family. The results of this study were as follows. 1. Planning of the housng unit for three generation family, it had to be taken over residency areas for elderly especially for keeping privacy each other. 2. It was necessary the criteria of housing standards for eldery based on their housing characteristics. 3. Considering the psychological characterstics and life style of the elderly, it should be suggest that they could live easily with their next generation in the samecommunity. Also, the public policy should take over the housing unit for three generation family.

• 지역사회간호학회지
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• 제12권2호
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• pp.406-416
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• 2001

This study is performed to confirm the influencing factors of family health protection behaviors using the variables included in Pender's Family Promotion Model. 1. The subjects are 110 families in preschooler family developmental stage, respondents are children's mother or father. These families are almost all nuclear types(95%), function of families is healthy as much as 8.0 the mean FAPGAR score. The prevalence rate of family members' illness was 14.7% these last 3 months, and 21.1 % of families responded suffered from injury for last 2 years. 2. The practice rate of injury prevention behavior is below a half in supervision and modifying of their home and residential environments, especially controlling through collaborative community power. The more familiar function score is the better practicing rates of injury prevention behaviors. 3. The injury prevention behaviors correlate to family size, health status of family member, and children's congenital defects with statistical significance. Families' economic condition correlates also significantly to family health status, cognition of benefits of injury prevention, cognition of the importance of community collecting power. And the recognition of the benefits of injury prevention correlates the adaptive health concept, family norms about injury prevention, economic status. 4. Considering family health promotion model. the general influencing factor is only affected to family protective behavior, and other paths don't affect to family's behaviors. In simple regression, the family protective behavior model explains 27.8%(P=0.05), significant factors are family function status, family size, chronic illness of family members', mother's education level. father's age. 5. To define of familiar preventive behavior as a unit is very important, but it has the limitation to solve the difficulties of family studies going with the operationalized difficulties of health promotion concept.

• 대한가정학회지
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• 제49권5호
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• pp.97-115
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• 2011

The focus of this study was on the self-differentiation level of families with an elderly member suffering from dementia. Based on 340 questionnaires collected in Seoul and Gyeonggi, the study intended to explain the adaptation issues of those families. The variables of interest, which might be related to the self-differentiation, were chronic anxiety(i.e. stress), the family function, psychosomatic symptoms and the family's adaptation to care-giving. As a result of analyzing the effects of the variables potentially related to the self-differentiation level of care-giving families, the findings from this study were as follow. With decreasing self-differentiation level of the family caring for an elderly member suffering from dementia, the levels of stress and psychosomatic symptoms were significantly increased, but the family function and the adaptation to care-giving tended to decrease. Conversely, with increasing self-differentiation, the levels of stress and psychosomatic symptoms were significantly decreased, while the family function and adaptation to care-giving were promoted.

• Molecules and Cells
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• 제44권5호
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• pp.342-355
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• 2021

The microphthalmia-associated transcription factor family (MiT family) proteins are evolutionarily conserved transcription factors that perform many essential biological functions. In mammals, the MiT family consists of MITF (microphthalmia-associated transcription factor or melanocyte-inducing transcription factor), TFEB (transcription factor EB), TFE3 (transcription factor E3), and TFEC (transcription factor EC). These transcriptional factors belong to the basic helix-loop-helix-leucine zipper (bHLH-LZ) transcription factor family and bind the E-box DNA motifs in the promoter regions of target genes to enhance transcription. The best studied functions of MiT proteins include lysosome biogenesis and autophagy induction. In addition, they modulate cellular metabolism, mitochondria dynamics, and various stress responses. The control of nuclear localization via phosphorylation and dephosphorylation serves as the primary regulatory mechanism for MiT family proteins, and several kinases and phosphatases have been identified to directly determine the transcriptional activities of MiT proteins. In different immune cell types, each MiT family member is shown to play distinct or redundant roles and we expect that there is far more to learn about their functions and regulatory mechanisms in host defense and inflammatory responses.

• 대한가정학회지
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• 제18권1호
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• pp.97-109
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• 1980

In Korea, the collapse of traditional Patriarchal family system has caused the weakening the patriarchal authority which represents the decrease of traditional attitude of respect for old age, influenced by the strong tendency of Materialism in ethics. The urgent problem is how to solve the conflicts of the alienation almost every old people has felt from the society and family which they belong to and how to harmonize the respect for old age who used to have had in the past. From 21st to 30th of July 1979, I explored the small village in Cheju Island with eight students which I selected on purpose that village had preserved the traditionalism. I collected the interview data form a sample of 221 persons of the village in Cheju Island. I studied this small village in Cheju Island for the intention of suggesting the ideal model of regional society which both traditional and non-formal, although the phenomena of nuclear family system and materialism and industrialism are overwhelming in ur present society. Generally people in Cheju Island are economically poor and major occupation is farming, since the industrialization proceeds very slowly and there still strongly remains the traditionalism. Alienation and dissatisfaction of old people from their family and society in Cheju island are less common in comparison to the main land. Old people in Cheju Island usually value the importance of labour. Divison of labour has been well observed in farming, and men and women in Cheju island are equally regarded in comparison to the main land. Old people are independent economically and spiritually from their offsprings and they organize the nuclear family system firmly. Also the old generation is ready to compromise with the new generation and they defy the authoritariansim.

• 가정과삶의질연구
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• 제11권1호
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• pp.176-190
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• 1993

This study intended to analyze the size and composition of social network and to identify their related variables in urban nuclear families. Data were collected through the questionnaires by wives living in Seoul area. The methods of statistical analysis used in the study were the frequency mean percentile and one-way ANOVA. The findings were as follows; 1) The size of social network in urban nuclear families was 10.0 in average and 2-33 in range. 2) The composition of social network were 45.5% in relatives 20.6% in neighbors. 21.8% in friends. 4,7% in coworkers, 4.1% religious group members 2.1% in associational members. and 1.4% in formal supporters. 3) The birth order of husbands was related to the size of social network. The composition of social network was influenced by SES family life cycle husband's birth order housing type residence duration age education employment religion and familism.

• Tuberculosis and Respiratory Diseases
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• 제46권2호
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• pp.185-194
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• 1999

연구배경: NF-$\kappa$B는 단백질이 생성된 후의 변형(post-translational modification)과 세포내에서의 위치 변화(subcellular localization)에 따라 그 작용이 결정되는 특성을 가진 전사 인자로서 최초에는 면역반응에 있어 중요한 역할을 하는 사실이 알려졌으나 그후 이러한 작용이외에도 급성기 염증 반응, 바이러스의 증식, 세포의 발생과 분화에 있어 중요한 작용을 한다는 사실이 알려지게 되었다. 최근의 연구들에서 NF-$\kappa$B 전사 인자가 정상 세포로부터 암세포로의 형질전환에 있어서도 어떤 기능을 할 것이라는 사실들이 알려지게 되었다. NF-$\kappa$B가 암세포로의 형질 전환, 나아가 암세포의 생성에 어떤 역할을 제공한다면 이러한 사실은 나아가 향후의 암치료에 있어서도 유용한 지식이 될 수 있다. NF-$\kappa$B 전사 인자가 인체 암세포에 있어서 세포의 형질 변환에 연관될 수 있다는 사실은 몇몇 암종에서 알려져 있으나 폐암에서의 NF-$\kappa$B 전사 인자의 종양 생성기능에 있어서는 아직 연구된 바가 없다. 방 법: 본 연구에서는 배양된 인체 폐암세포주에 있어서 NF-$\kappa$B family 전사 인자들의 발현정도를 western blot를 이용하여 관찰하고 과발현된 NF-$\kappa$B 전사 인자의 세포내 위치가 세포핵인지 세포질내에 존재하는 것인지를 각각의 단백질 분획에서 western blot를 시행하여 관찰하였고 또한 immunocy-tochemistry를 시행하여 그 발현 양상을 확인하였다. 존재하는 NF-$\kappa$B 전사 인자가 어떠한 복합체의 형태인지를 알아보기 위하여 세포주의 단백 추출물에서 NF-$\kappa$B family 전사 인자에 대한 항체를 사용하여 immunoprecipitation을 시행하였다. 세포주 단백추출물의 $\kappa$B consensus oligonucleotide에의 결합여부를 보기위하여 electrophoretic mobility shift assay를 시행하였다. 결 과: 배양된 인체 폐암세포주에서는 NF-$\kappa$B family의 p50 subunit, p65 subunit가 발현되어 있었고 p50 subunit의 발현은 세포핵내에 국한하여 위치하고 있음을 western blot와 immunocytochemistry를 통하여 관찰할 수 있었다 immunoprecipitation assay는 세포내에서 p50 subunit가 p65 subunit와 복합체를 이루는 상태로 존재하고 있음을 보여주었다. 폐암세포주의 세포핵 추출물은 NF-$\kappa$B consensus oligonucleotide와 결합할 수 있음을 electrophoretic mobility shift assay를 통하여 확인할 수 있었다. 결 론: 인체 폐암세포주에서 NF-$\kappa$B family 전사 인자의 발현이 활성화되어 있으며 NF-$\kappa$B family 전사 영자가 인체 폐암 형성에 있어 어떤 역할을 할 가능성을 시사한다.

• 한국콘텐츠학회논문지
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• 제22권5호
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• pp.553-564
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• 2022

이 연구의 목적은 <삼시세끼> 어촌편 1이 재현한 가족을 살펴보는 것으로, 이야기 전개구성과 등장인물의 관계 특성을 서사분석을 활용해 분석하였다. <삼시세끼>는 '기상-자유시간-아침-점심-저녁-휴식-취침'의 비교적 단순한 전개구성을 보였다. 각 등장인물에게는 주된 공간과 역할을 배치함으로써 '차줌마', '바깥양반', '호주니'의 캐릭터를 완성해갔다. 출연진이 모두 남성임에도 이들에게는 아내/주부/엄마, 남편/가장/아빠, 아들의 가족지위가 부여되었고, 매우 고정된 감정과 획일적 행동의 가족실천이 탄탄한 관계구조 속에서 반복되었다. 동시에 유자녀 가족, 양부모 가족, 이성애가족, 핵가족이라는 전형적 근대가족, 정상가족, 표준가족을 연출하였다. 즉 <삼시세끼>는 스위트 홈의 표상을 적극 차용해 정상가족 이데올로기를 강화시켰다.

• 대한핵의학회:학술대회논문집
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• 대한핵의학회 2000년도 2nd Korea-China Congress of Nuclear Medicine and 39th Annual Spring Meeting if the Korea SOciety Nuclear Medicine
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• pp.71.1-71.1
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• 2000

• 인문언어
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• 제1권2호
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• pp.161-178
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• 2001

This study investigates how Korean traditional family consciousness interacts with Korean industrialization in the 1970s. In Our Children, Lee Sun depicts a family's struggle within the turmoil brought about by rapid industrialization to escape from the ranks of the working class. It is well known that one of the consequences of industrialization was the breakup of the larger family structure into nuclear families, but Lee Sun presents Korea's industrialization in the 1970s in the light of the traditional Korean family culture before the breakup. In other words, he gives us a portrayal of Gemeinschaft in Gesellschaft in his description of the extended family's struggle to overcome the day-to-day pressures of modernization and urbanization. The novel presents three generations of a traditional extended family. The eldest son is portrayed as a knife, strong and sharp. His wife has a temporary job that she hopes to give up once they own a house, which symbolizes the family's escape from the working class. The relationship among the family members reveals the core aspects of the ideology governing traditional extended families: the husband is the despotic monarch of the household, solely responsible for the family's economy; the husband is the sky and the wife the earth; and children (the more the better) are expected to lead to stability, welfare, and prosperity. One curious aspect of this family relationship as portrayed by Lee Sun is the expectation that being the eldest son, who already is or will become the patriarch of the family, is the fastest way of reaching middle-class status. And, despite a slight reversal, the novel has a happy ending wherein the family's expectations are fulfilled without much suffering. This aspect should be considered in light of the revolutionary romantic idealism of the novels of the 1930s. The lack of suffering and the easy happy ending may be attributed to the fact that Korea's industrialization came about rapidly and radically, and therefore it is likely that Lee Sun was not able fully to appreciate the full costs of industrialization. This limitation calls for a deeper investigation into the social structure and class consciousness of the 1970s, and also a study of the intertextual relationship of Our Children with other novels of the time.