• 제목/요약/키워드: novel member

검색결과 203건 처리시간 0.044초

Molecular Cloning of a Defensin Homologue Gene of a Novel Family Member from the Firefly, Pyrocoelia rufa

  • Lee, Kwang-Sik;Park, Hye-Jin;Kim, Seong-Ryul;Lee, Sang-Mong;Sohn, Hung-Dae;Jin, Byung-Rae
    • International Journal of Industrial Entomology and Biomaterials
    • /
    • 제3권1호
    • /
    • pp.57-62
    • /
    • 2001
  • A cDNA encoding the defensin homologue of a novel family member was isolated from the cDNA library of the firefly,Pyrocoelia rufa. Sequence analysis of the cDNA encoding the defensin homologue of P. rufa resulted that the 165 bp cDHA has an open reading frame of 55 amino acid residues. The deduced amino acid sequences of the defensin homologue gene from P. rufa showed identity to known mammalian defensins. Also 6 cystein residues in the P. rufa defensin homologue gene were conserved in the same position as those of known mammalian defensins. The result suggested that P. rufa defensin homologue is a novel member of the insect defensin family. Southern blot analysis suggests that there may be a single copy number of the P.rufa defensin homologue gene and their fat body-specific expression pattern at the transcriptional level was confirmed by Northern blot analysis.

  • PDF

Novel Packet Switching for Green IP Networks

  • Jo, Seng-Kyoun;Kim, Young-Min;Lee, Hyun-Woo;Kangasharju, Jussi;Mulhauser, Max
    • ETRI Journal
    • /
    • 제39권2호
    • /
    • pp.275-283
    • /
    • 2017
  • A green technology for reducing energy consumption has become a critical factor in ICT industries. However, for the telecommunications sector in particular, most network elements are not usually optimized for power efficiency. Here, we propose a novel energy-efficient packet switching method for use in an IP network for reducing unnecessary energy consumption. As a green networking approach, we first classify the network nodes into either header or member nodes. The member nodes then put the routing-related module at layer 3 to sleep under the assumption that the layer in the OSI model can operate independently. The entire set of network nodes is then partitioned into clusters consisting of one header node and multiple member nodes. Then, only the header node in a cluster conducts IP routing and its member nodes conduct packet switching using a specially designed identifier, a tag. To investigate the impact of the proposed scheme, we conducted a number of simulations using well-known real network topologies and achieved a more energy- efficient performance than that achieved in previous studies.

트러스 구조물 사이즈 최적화를 위한 무응력 부재의 선택 (Zero-Stress Member Selection for Sizing Optimization of Truss Structures)

  • 이승혜;이종현;이기학;이재홍
    • 한국공간구조학회논문집
    • /
    • 제21권1호
    • /
    • pp.61-70
    • /
    • 2021
  • This paper describes a novel zero-stress member selecting method for sizing optimization of truss structures. When a sizing optimization method with static constraints is implemented, the member stresses are affected sensitively with changing the variables. However, because some truss members are unaffected by specific loading cases, zero-stress states are experienced by the elements. The zero-stress members could affect the computational cost and time of sizing optimization processes. Feature selection approaches can be then used to eliminate the zero-stress member from the whole variables prior to the process of optimization. Several numerical truss examples are tested using the proposed methods.

Novel Impulsive Driving Schemes for 120Hz LCD Panels

  • Nam, Hyoung-Sik;Oh, Jae-Ho;Shin, Byung-Hyuk;Oh, Kwan-Young;Berkeley, Brian H.;Kim, Nam-Deog;Kim, Sang-Soo
    • Journal of Information Display
    • /
    • 제9권1호
    • /
    • pp.1-5
    • /
    • 2008
  • Two new impulsive driving technologies for 120Hz liquid crystal display (LCD) panels are proposed to improve moving picture quality. One technology generates the dark frame using an adder and a shifter simply without using any look up tables (LUTs). It results in a cost effective impulsive scheme with motion picture quality comparable to that of high speed driving. The other is a backlight flashing method designed to avoid ghost images. The issue of ghost images caused by the slow response time of liquid crystal (LC) is solved by means of 120Hz overdriving and 120Hz backlight flashing. Using the perceived blur edge time (PBET) metric, measured moving picture response time (MPRT) values were 10.8ms and 4.4ms, respectively, while that of 120Hz high speed driving was 10.1ms.

A Novel Jamming Detection Technique for Wireless Sensor Networks

  • Vijayakumar, K.P.;Ganeshkumar, P.;Anandaraj, M.
    • KSII Transactions on Internet and Information Systems (TIIS)
    • /
    • 제9권10호
    • /
    • pp.4223-4249
    • /
    • 2015
  • A novel jamming detection technique to detect the presence of jamming in the downstream direction for cluster based wireless sensor networks is proposed in this paper. The proposed technique is deployed in base station and in cluster heads. The proposed technique is novel in two aspects: Firstly, whenever a cluster head receives a packet it verifies whether the source node is legitimate node or new node. Secondly if a source node is declared as new node in the first step, then this technique observes the behavior of the new node to find whether the new node is legitimate node or jammed node. In order to monitor the behavior of the existing node and new node, the second step uses two metrics namely packet delivery ratio (PDR) and received signal strength indicator (RSSI). The rationality of using PDR and RSSI is presented by performing statistical test. PDR and RSSI of every member in the cluster is measured and assessed by the cluster head. And finally the cluster head determines whether the members of the cluster are jammed or not. The CH can detect the presence of jamming in the cluster at member level. The base station can detect the presence of jamming in the wireless sensor network at CH level. The simulation result shows that the proposed technique performs extremely well and achieves jamming detection rate as high as 99.85%.

Innovative displacement-based beam-column element with shear deformation and imperfection

  • Tang, Yi-Qun;Ding, Yue-Yang;Liu, Yao-Peng;Chan, Siu-Lai;Du, Er-Feng
    • Steel and Composite Structures
    • /
    • 제42권1호
    • /
    • pp.75-90
    • /
    • 2022
  • The pointwise equilibrium polynomial (PEP) element considering local second-order effect has been widely used in direct analysis of many practical engineering structures. However, it was derived according to Euler-Bernoulli beam theory and therefore it cannot consider shear deformation, which may lead to inaccurate prediction for deep beams. In this paper, a novel beam-column element based on Timoshenko beam theory is proposed to overcome the drawback of PEP element. A fifth-order polynomial is adopted for the lateral deflection of the proposed element, while a quadric shear strain field based on equilibrium equation is assumed for transverse shear deformation. Further, an additional quadric function is adopted in this new element to account for member initial geometrical imperfection. In conjunction with a reliable and effective three-dimensional (3D) co-rotational technique, the proposed element can consider both member initial imperfection and transverse shear deformation for second-order direct analysis of frame structures. Some benchmark problems are provided to demonstrate the accuracy and high performance of the proposed element. The significant adverse influence on structural behaviors due to shear deformation and initial imperfection is also discussed.

Genome Sequence of Spinach Cryptic Virus 1, a New Member of the Genus Alphapartitivirus (Family Partitiviridae), Identified in Spinach

  • Park, Dongbin;Hahn, Yoonsoo
    • Journal of Microbiology and Biotechnology
    • /
    • 제27권4호
    • /
    • pp.834-837
    • /
    • 2017
  • A distinct double-stranded RNA (dsRNA) cryptic virus, named spinach cryptic virus 1 (SpCV1), was identified from spinach transcriptome datasets. The SpCV1 genome has two dsRNA genome segments. The larger dsRNA1 has an open reading frame for a conserved RNA-dependent RNA polymerase (RdRp). The smaller dsRNA2 encodes a putative coat protein (CP). The sequence identity of SpCV1 RdRp and CP to the closest cryptic virus is 81% and 60%, respectively. Phylogenetic analysis indicates that SpCV1 is a novel member of the genus Alphapartitivirus (family Partitiviridae).

Design optimization of reinforced concrete structures

  • Guerra, Andres;Kiousis, Panos D.
    • Computers and Concrete
    • /
    • 제3권5호
    • /
    • pp.313-334
    • /
    • 2006
  • A novel formulation aiming to achieve optimal design of reinforced concrete (RC) structures is presented here. Optimal sizing and reinforcing for beam and column members in multi-bay and multistory RC structures incorporates optimal stiffness correlation among all structural members and results in cost savings over typical-practice design solutions. A Nonlinear Programming algorithm searches for a minimum cost solution that satisfies ACI 2005 code requirements for axial and flexural loads. Material and labor costs for forming and placing concrete and steel are incorporated as a function of member size using RS Means 2005 cost data. Successful implementation demonstrates the abilities and performance of MATLAB's (The Mathworks, Inc.) Sequential Quadratic Programming algorithm for the design optimization of RC structures. A number of examples are presented that demonstrate the ability of this formulation to achieve optimal designs.

Inhibitory Potential of Bilobetin Against CYP2J2 Activities in Human Liver Microsomes

  • Wu, Zhexue;Jang, Su-Nyeong;Park, So-Young;Phuc, Nguyen Minh;Liu, Kwang-Hyeon
    • Mass Spectrometry Letters
    • /
    • 제11권4호
    • /
    • pp.113-117
    • /
    • 2020
  • Cytochrome P450 2J2 (CYP2J2) is a member of the cytochrome P450 superfamily, and is known to be arachidonic acid epoxygenase that mediates the formation of four bioactive regioisomers of epoxyeicosatrienoic acids (EETs). CYP2J2 is also involved in the metabolism of drugs such as albendazole, astemizole, danazol, ebastine, and terfenadine. CYP2J2 is highly expressed in the heart and cancer tissues. In this study, the inhibitory potential of ten natural products against CYP2J2 activity was evaluated using human liver microsomes and tandem mass spectrometry. Among them, bilobetin, which is a kind of biflavonoid, exhibits a strong inhibitory effect against the CYP2J2-mediated astemizole O-demethylation (IC50 = 0.73 μM) and terfenadine hydroxylation (IC50 = 0.89 μM). This result suggests that bilobetin can be used as strong CYP2J2 inhibitor in drug metabolism study.

The identification of novel regions for reproduction trait in Landrace and Large White pigs using a single step genome-wide association study

  • Suwannasing, Rattikan;Duangjinda, Monchai;Boonkum, Wuttigrai;Taharnklaew, Rutjawate;Tuangsithtanon, Komson
    • Asian-Australasian Journal of Animal Sciences
    • /
    • 제31권12호
    • /
    • pp.1852-1862
    • /
    • 2018
  • Objective: The purpose of this study was to investigate a single step genome-wide association study (ssGWAS) for identifying genomic regions affecting reproductive traits in Landrace and Large White pigs. Methods: The traits included the number of pigs weaned per sow per year (PWSY), the number of litters per sow per year (LSY), pigs weaned per litters (PWL), born alive per litters (BAL), non-productive day (NPD) and wean to conception interval per litters (W2CL). A total of 321 animals (140 Landrace and 181 Large White pigs) were genotyped with the Illumina Porcine SNP 60k BeadChip, containing 61,177 single nucleotide polymorphisms (SNPs), while multiple traits single-step genomic BLUP method was used to calculate variances of 5 SNP windows for 11,048 Landrace and 13,985 Large White data records. Results: The outcome of ssGWAS on the reproductive traits identified twenty-five and twenty-two SNPs associated with reproductive traits in Landrace and Large White, respectively. Three known genes were identified to be candidate genes in Landrace pigs including retinol binding protein 7, and ubiquitination factor E4B genes for PWL, BAL, W2CL, and PWSY and one gene, solute carrier organic anion transporter family member 6A1, for LSY and NPD. Meanwhile, five genes were identified to be candidate genes in Large White, two of which, aldehyde dehydrogenase 1 family member A3 and leucine rich repeat kinase 1, associated with all of six reproduction traits and three genes; retrotransposon Gag like 4, transient receptor potential cation channel subfamily C member 5, and LHFPL tetraspan subfamily member 1 for five traits except W2CL. Conclusion: The genomic regions identified in this study provided a start-up point for marker assisted selection and estimating genomic breeding values for improving reproductive traits in commercial pig populations.