• Genomics & Informatics
• /
• v.2 no.2
• /
• pp.92-98
• /
• 2004

A cDNA microarray experiment is one of the most useful high-throughput experiments in medical informatics for monitoring gene expression levels. Statistical analysis with a cDNA microarray medical data requires a normalization procedure to reduce the systematic errors that are impossible to control by the experimental conditions. Despite the variety of normalization methods, this. paper suggests a more general and synthetic normalization algorithm with a control gene set based on previous studies of normalization. Iterative normalization method was used to select and include a new control gene set among the whole genes iteratively at every step of the normalization calculation initiated with the housekeeping genes. The objective of this iterative normalization was to maintain the pattern of the original data and to keep the gene expression levels stable. Spatial plots, M&A (ratio and average values of the intensity) plots and box plots showed a convergence to zero of the mean across all genes graphically after applying our iterative normalization. The practicability of the algorithm was demonstrated by applying our method to the data for the human photo aging study.

• Journal of Multimedia Information System
• /
• v.2 no.3
• /
• pp.275-280
• /
• 2015

Recently brainwaves are utilized diversely in the field of medicine, entertainment, education and so on. In the case of medicine, brainwaves are analyzed to estimate patients' diseases. However, the applications for entertainments usually utilize brainwaves as control signal without figuring out the characters of the brainwaves. Given that users' brainwaves are different each other, a normalization method is essential. The traditional brainwave normalization approaches utilize normal distribution. However, those approaches assume that brainwaves are collected enough to conduct normal distribution. When the few amounts of brainwaves are measured, the accuracy of the control signal based on the measured brainwaves becomes low. In this paper, we propose a normalization framework of BCI-based facial interfaces for novel volume controllers, which can normalizes the few amounts of brainwaves and then generates the control signals of BCI-based facial interfaces. In the experiments, two subjects were involved to validate the proposed framework and then the normalization processes were introduced.

• 제어로봇시스템학회:학술대회논문집
• /
• 2005.06a
• /
• pp.2385-2388
• /
• 2005

In this paper, we propose the estimation method for the image affine information for computer vision. The first estimation method is given based on the XYS image normalization and the second estimation method is based on the image normalization by Pei and Lin. The XYS normalization method turns out to have better performance than the method by Pei and Lin. In addition, we show that rotation and aspect ratio information can be obtained using the central moments of both the original image and the sensed image. Finally, we propose the modified version of the normalization method so that we may control the size of the image.

• Physical Therapy Korea
• /
• v.14 no.3
• /
• pp.32-40
• /
• 2007

Although many children with cerebral palsy have problems with their eye movements available data on its intervention is minimal. The purpose of the study was to determine the effectiveness of the postural movement normalization and eye movement program on the oculomotor ability of children with cerebral palsy. Twenty-four children with cerebral palsy (12 male and 12 female), aged between 10 and 12, were invited to partake in this study. The subjects were randomly allocated to two groups: an experimental group received the postural movement normalization and eye movement program and a control group which received conventional therapy without the eye movement program. Each subject received intervention three times a week for twelve weeks. The final measurement was the ocular motor computerized test before and after treatment sessions through an independent assessor. Differences between the experimental group and control group were determined by assessing changes in oculomotor ability using analysis of covariance (ANCOVA). The changes of visual fixation (p<.01), saccadic eye movement (p<.01) and pursuit eye movement (p<.01) were significantly higher in the experimental group than in the control group. These results show that the postural movement normalization and eye movement program may be helpful to treat children with cerebral palsy who lose normal physical and eye movement.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
• /
• v.36 no.6
• /
• pp.515-523
• /
• 2018

In order to obtain consistent change detection result for multi-temporal satellite images, preprocessing must be performed. In particular, the preprocessing related to the spectral values can be performed by the radiometric normalization, and relative radiometric normalization is generally utilized. However, most relative radiometric normalization methods assume a linear relationship between the two images, and nonlinear spectral characteristics such as phenological differences are not considered. Therefore, this study proposes a relative radiometric normalization which assumes nonlinear relationships that can perform compositive normalization of radiometric and phenological characteristics. The proposed method selects the subject and reference images, and then extracts the radiometric control set samples through the no-change method. In addition, spectral indexes as well as pixel values are extracted in order to consider sufficient information, and modeling of nonlinear relationships is performed through multilayer perceptron. Finally, the proposed method is compared with the conventional relative radiometric normalization methods, which shows that the proposed method is visually and quantitatively superior.

• The Journal of the Acoustical Society of Korea
• /
• v.35 no.4
• /
• pp.280-287
• /
• 2016

In this paper, we propose a normalization algorithm that can be applied to adaptive filters for multi-channel active noise control. The FxLMS (Filtered-x Least Mean Square) algorithm for the single-channel active noise control can be normalized in the same way as the NLMS (Normalized Least Mean Square) algorithm, whereas in case of the multi-channel active noise control, the single-channel normalization for the FxLMS algorithm cannot be extended to the normalization for the multi-channel FxLMS algorithm straightforwardly. First, we adopt a generalized normalization algorithm for the multi-channel FxLMS algorithm based on the principle of minimal disturbance and then, proposed a normalized algorithm considering only diagonal elements to avoid computation for matrix inversion. We carried out performance comparisons of the proposed algorithm with other algorithms without normalization. It is shown that the proposed algorithm presents better convergence characteristics under non-stationary environments.

• 제어로봇시스템학회:학술대회논문집
• /
• 2003.10a
• /
• pp.1140-1145
• /
• 2003

Image normalization is one of the important areas in pattern recognition. Also, log-polar images are useful in the sense that their image data size is reduced dramatically comparing with conventional images and it is possible to develop faster pattern recognition algorithms. Especially, the log-polar image is very similar with the structure of human eyes. However, there are almost no researches on pattern recognition using the log-polar images while a number of researches on visual tracking have been executed. We propose an image normalization technique of log-polar images using momentums applicable for affine-invariant pattern recognition. We handle basic distortions of an image including translation, rotation, scaling, and skew of a log-polar image. The algorithm is experimented in a PC-based real-time vision system successfully.

• The Korean Journal of Nuclear Medicine Technology
• /
• v.27 no.1
• /
• pp.47-54
• /
• 2023

Purpose PET-CT imaging require an appropriate quality assurance system to achieve high efficiency and reliability. Quality control is essential for improving the quality of care and patient safety. Currently, there are performance evaluation methods of UN2-1994 and UN2-2001 proposed by NEMA and IEC for PET-CT image evaluation. In this study, we compare phantom images with the same experiments before and after PET-CT 3D normalization and well counter correction and evaluate the usefulness of quality control. Materials and methods Discovery 690 (General Electric Healthcare, USA) PET-CT equiptment was used to perform 3D normalization and well counter correction as recommended by GE Healthcare. Based on the recovery coefficients for the six spheres of the NEMA IEC Body Phantom recommended by the EARL. 20kBq/㎖ of ¹⁸F was injected into the sphere of the phantom and 2kBq/㎖ of ¹⁸F was injected into the body of phantom. PET-CT scan was performed with a radioacitivity ratio of 10:1. Images were reconstructed by appliying TOF+PSF+TOF, OSEM+PSF, OSEM and Gaussian filter 4.0, 4.5, 5.0, 5.5, 6.0, 6,5 mm with matrix size 128×128, slice thickness 3.75 mm, iteration 2, subset 16 conditions. The PET image was attenuation corrected using the CT images and analyzed using software program AW 4.7 (General Electric Healthcare, USA). The ROI was set to fit 6 spheres in the CT image, RC (Recovery Coefficient) was measured after fusion of PET and CT. Statistical analysis was performed wilcoxon signed rank test using R. Results Overall, after the quality control items were performed, the recovery coefficient of the phantom image increased and measured. Recovery coefficient according to the image reconstruction increased in the order TOF+PSF, TOF, OSEM+PSF, before and after quality control, RCmax increased by OSEM 0.13, OSEM+PSF 0.16, TOF 0.16, TOF+PSF 0.15 and RCmean increased by OSEM 0.09, OSEM+PSF 0.09, TOF 0.106, TOF+PSF 0.10. Both groups showed a statistically significant difference in Wilcoxon signed rank test results (P value<0.001). Conclusion PET-CT system require quality assurance to achieve high efficiency and reliability. Standardized intervals and procedures should be followed for quality control. We hope that this study will be a good opportunity to think about the importance of quality control in PET-CT

• Proceedings of the KIPE Conference
• /
• 2002.07a
• /
• pp.300-303
• /
• 2002

With increase of servo motor In industrial and home application, a number of papers related to PMSM control have been researched. Among them, sensorless control schemes are especially concerned in the view point of its cost reduction. In the conventional approach, a rotor position is generally estimated by the integration of estimated rotor speed. In this method, because of their tight relationship between the amplitude of back-emf and rotor position. it is somewhat difficult to find two parameters at the same time. To solve this problem, a novel sensorless control scheme is proposed. It utilizes a back-emf normalization, so it does not requires the variables related with the amplitude of back-emf. The validity of the proposed control scheme was verified through experimental results.

• Proceedings of the KIPE Conference
• /
• 2005.07a
• /
• pp.251-253
• /
• 2005

This paper presents a study on a current control of a PM synchronous motor which is fed by two-level voltage source inverter in the high modulation index area. In order to increase dynamic response and extend speed limit caused by voltage limit, overmodulation method is generally used. The current control in overmodulation have voltage limit. So larger voltage command than voltage limit should be diminished. In this paper, the problem conventional normalization method is analyzed and New normalization method in overmodulation region is proposed.