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Acute Temporary Visual Loss after General Anesthesia in a Cat (전신 마취 후 발생한 고양이의 일시적인 급성 시력상실 1례)

  • Son, Won-Gyun;Jung, Bo-Young;Kwon, Tae-Eog;Seo, Kang-Moon;Lee, In-Hyung
    • Journal of Veterinary Clinics
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    • v.26 no.5
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    • pp.480-482
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    • 2009
  • A 2-year-old, castrated male, Scottish fold cat was referred to Veterinary Medical Teaching Hospital of Seoul National University (VMTH-SNU) for evaluation of acute bilateral blindness after general anesthesia. For dental prophylaxis in local animal hospital, general anesthesia had been induced with intravenous acepromazine and ketamine, and maintained with isoflurane after intubation. At VMTH-SNU on next day, complete blood count, electrolytes and serum chemistry values were within normal ranges. On neurologic examination, visual placing and postural reactions like as hopping, hemiwalking and wheelborrowing were reduced on right hindlimb. On ophthalmic examination, menace responses were absent on both eyes and pupillary light reflex (PLR) reduced on right eye, but other reflex and fundus were normal. Prednisolone (2 mg/kg sid for 3 days) was administrated orally and tapered. Visual placing was possible on 2nd day, and postural reactions were recovered on 4th day after dental prophylaxis. Based on the process and recovery, this case was considered as postoperative visual loss (POVL) after general anesthesia.

Effects of Muscle Mass and Fiber Number of Longissimus dorsi Muscle on Post-mortem Metabolic Rate and Pork Quality

  • Ryu, Youn-Chul;Choi, Young-Min;Kim, Byoung-Chul
    • Food Science and Biotechnology
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    • v.14 no.5
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    • pp.667-671
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    • 2005
  • The aim of this study is to investigate the effects of the muscle mass and fiber number on post-mortem metabolic rates and pork quality. Carcass traits, muscle fiber characteristics, and type of fiber composition were evaluated using a sample of 200 cross-bred pigs. The muscle mass was divided into two groups according to carcass weight and loin-eye area measurements (heavy or light). In addition, the muscle histological characteristics were divided into two groups according to the muscle fiber density and total number of muscle fibers (high or low). All the carcass traits were significantly different in the muscle mass groups. Increasing weight significantly affected the cross-sectional area (CSA) of all fibers. The low group, which had a low muscle fiber number indicating a larger CSA of fibers, and especially the heavy-low group had the highest CSA levels of fibers. The fiber number percentage and the area percentage were significantly different in the groups categorized by fiber number. The heavy-high group indicated a normal rate of pH decline and the R-value. In addition, pigs with a heavy muscle mass and high muscle fiber number indicated normal drip loss, lightness, and protein denaturation. The present results suggest that increasing the total muscle fiber number has a beneficial effect on increasing the muscle mass without deteriorating the meat quality.

Physiology of sleep (수면의 생리)

  • Chae, Kyu Young
    • Clinical and Experimental Pediatrics
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    • v.50 no.8
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    • pp.711-717
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    • 2007
  • Sleep is a vital, highly organized process regulated by complex systems of neuronal networks and neurotransmitters. Normal sleep comprises non-rapid eye movement (NREM) and REM periods that alternate through the night. Sleep usually begins in NREM and progresses through deeper NREM stages (2, 3, and 4 stages), but newborns enter REM sleep (active sleep) first before NREM (quiet sleep). A period of NREM and REM sleep cycle is approximately 90 minutes, but newborn have a shorter sleep cycle (50 minutes). As children mature, sleep changes as an adult pattern: shorter sleep duration, longer sleep cycles and less daytime sleep. REM sleep is approximately 50% of total sleep in newborn and dramatically decreases over the first 2 years into adulthood (20% to 25%). An initial predominant of slow wave sleep (stage 3 and 4) that peaks in early childhood, drops off abruptly after adolescence by 40% from preteen years, and then declines over the life span. The hypothalamus is recognized as a key area of brain involved in regulation of sleep and wakefulness. The basic function of sleep largely remains elusive, but it is clear that sleep plays an important role in the regulation of CNS and body physiologic processes. Understanding of the architecture of sleep and basic mechanisms that regulate sleep and wake cycle are essential to evaluate normal or abnormal development of sleep pattern changes with age. Reduction or disruption of sleep can have a significant impact on daytime functioning and development, including learning, growth, behavior, and emotional regulation.

Computational electroencephalography analysis for characterizing brain networks

  • Sunwoo, Jun-Sang;Cha, Kwang Su;Jung, Ki-Young
    • Annals of Clinical Neurophysiology
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    • v.22 no.2
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    • pp.82-91
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    • 2020
  • Electroencephalography (EEG) produces time-series data of neural oscillations in the brain, and is one of the most commonly used methods for investigating both normal brain functions and brain disorders. Quantitative EEG analysis enables identification of frequencies and brain activity that are activated or impaired. With studies on the structural and functional networks of the brain, the concept of the brain as a complex network has been fundamental to understand normal brain functions and the pathophysiology of various neurological disorders. Functional connectivity is a measure of neural synchrony in the brain network that refers to the statistical interdependency between neural oscillations over time. In this review, we first discuss the basic methods of EEG analysis, including preprocessing, spectral analysis, and functional-connectivity and graph-theory measures. We then review previous EEG studies of brain network characterization in several neurological disorders, including epilepsy, Alzheimer's disease, dementia with Lewy bodies, and idiopathic rapid eye movement sleep behavior disorder. Identifying the EEG-based network characteristics might improve the understanding of disease processes and aid the development of novel therapeutic approaches for various neurological disorders.

Face Pose Estimation using Stereo Image (스테레오 영상을 이용한 얼굴 포즈 추정)

  • So, In-Mi;Kang, Sun-Kyung;Kim, Young-Un;Lee, Chi-Geun;Jung, Sung-Tae
    • Journal of the Korea Society of Computer and Information
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    • v.11 no.3
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    • pp.151-159
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    • 2006
  • In this paper. we Present an estimation method of a face pose by using two camera images. First, it finds corresponding facial feature points of eyebrow, eye and lip from two images After that, it computes three dimensional location of the facial feature points by using the triangulation method of stereo vision techniques. Next. it makes a triangle by using the extracted facial feature points and computes the surface normal vector of the triangle. The surface normal of the triangle represents the direction of the face. We applied the computed face pose to display a 3D face model. The experimental results show that the proposed method extracts correct face pose.

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Evaluation of the Lens Absorbed Dose of MVCT and kV-CBCT Use for IMRT to the Nasopharyngeal Cancer Patient (비인두암 환자에 대한 세기조절 방사선치료 시 이용되는 MVCT와 kV-CBCT의 수정체 흡수선량 평가)

  • Choi, Jae Won;Kim, Cheol Chong;Park, Su Yeon;Song, Ki Weon
    • The Journal of Korean Society for Radiation Therapy
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    • v.25 no.2
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    • pp.131-136
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    • 2013
  • Purpose: Quantitative comparative evaluation of the difference in eye lens absorbed dose when measured by MVCT and kV-CBCT, though such a dose was not included in the original IMRT treatment plan for the nasopharyngeal cancer patient. Materials and Methods: We used CT (Lightspeed Ultra 16, General Electric, USA) against an Anderson rando phantom (Alderson Research Laboratories Inc, USA) and established the plan for tomotherapy treatment (Tomotherapy, Inc, USA) and linear accelerator treatment (Pinnacle 8.0, Philips Medicle System) for the achieved CT images on the same condition with the nasopharyngeal cancer patient treatment plan. Then, align the ther-moluminescence dosimeter (TLD100 Harshaw, USA) with the eye lens, shot the lens with Tomotherapy MVCT under 3 conditions (Fine, Normal, and Coarse), and shot both lenses with kV-CBCT under 2 conditions (Low Dose Head and Standard Dose Head) 3 times each. Results: When we analyzed the eye lens absorbed dose according to MVCT and kV-CBCT images by using both Tomotherapy and Pinacle 8.0, we achieved the following result; According to Tomotherapy MVCT, RT 0.8257 cGy in the Coarse mode, LT 0.8137 cGy, RT 1.089 cGy and LT 1.188 cGy in the Normal mode, and RT 2.154 cGy and LT 2.082 cGy in the Fine mode. According to Pinacle 8.0 kV-CBCT, RT 0.2875 cGy and LT 0.1676 cGy in the Standard Dose mode and RT 0.1648 cGy and LT 0.1212 cGy in the Low-Dose mode. In short, the MVCT result was significantly different from that of kV-CBCT, up to 20 times. Conclusion: We think kV-CBCT is more effective for reducing the amount of radiation which a patient is receiving during intensity modulated radiation treatment for other purposes than treatment than MVCT, when we consider the absorbed dose only from the viewpoint of image-guided radiation therapy. Besides, we understood the amount of radiation is too sensitive to the shooting condition, even when we use the same equipment.

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Simple and Rapid Detection of Potato leafroll virus by Reverse Transcription Loop-mediated Isothermal Amplification

  • Ju, Ho-Jong
    • The Plant Pathology Journal
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    • v.27 no.4
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    • pp.385-389
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    • 2011
  • A new reverse transcription loop-mediated isothermal amplification (RT-LAMP) method for the Potato leafroll virus (PLRV) was developed and compared with conventional reverse transcription polymerase chain reaction (RT-PCR) to address its advantages over RTPCR. RT-LAMP primers were designed from the open reading frame 3 (ORF3) sequence of PLRV. The RT-LAMP reactions were conducted without or with a set of loop primers. By real-time monitoring using Turbimeter, the RT-LAMP (with loop primers) detects PLRV in less than 30 min, compared to 120 min of RT-PCR. By adding fluorescent reagent during the reaction, final products of the RT-LAMP were fluorescently visualized under UV light or could be differentiated by naked-eye inspection under normal light. The RT-LAMP was extremely sensitive, about 2000-fold more sensitive than RT-PCR. This study presents great potential of the RT-LAMP for diagnosis and PLRV epidemiology because RT-LAMP method is speedy, sensitive, inexpensive, and convenient.

Frontal Sinus Mucocele with Massive Skull Destruction

  • Choi, Hwan-Young;Lee, Hyung-Jin;Yang, Ji-Ho;Lee, Il-Woo
    • Journal of Korean Neurosurgical Society
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    • v.40 no.4
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    • pp.285-288
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    • 2006
  • A 63-year-old female complained of left frontal headache and swelling for several months. Physical examination revealed left supraorbital soft, nontender, nonpulsatile mass without bruit. The left eye was displaced downward with respect to the normal right globe. Based on the clinical and radiological findings, the patient was diagnosed as a mucocele arising from the left frontal sinus. The patient underwent a transcranial approach through coronal incision. In this patient, large portions of the anterior and posterior frontal sinus walls were destroyed in association with epidural spread, so we performed cranialization of the frontal sinus and removed the mucosal wall with the aid of a microscope. With a brief review we present a patient with mucocele of the frontal sinus extending into the intracranial and intraorbital region, which was successfully treated by a transcranial approach.

Four Cases of Stroke Patients with Defective Vision Treated with Venesection on Palpebral Conjunctiva (眼瞼結膜 刺絡療法(棘鍼療法)을 시술한 中風 환자의 眼昏 치험 4例)

  • Ock, Min-keun;Lim, Woong-kyoung;Yoon, Hyoung-seon;Sun, Young-jae;Moon, Jang-hyuk;Kim, Chang-hwan
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.17 no.3
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    • pp.107-113
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    • 2004
  • Objective: This study was performed to evaluate the effects of venesection on palpebral conjunctiva, on the stoke patients complaint of defective vision. Methods: We studied four selected stroke patients with defective vision which start with stroke. Venesection was performed with syringe needleonce or several times on upper or lower palpebral conjunctiva. After every venesection we washed the eye(s) with normal saline. We evaluated the effects by VAS. Results & conclusion: Venesection on palpebral conjunctiva was efficacious against defective vision occured on the stoke patients. But more clinical & scienific trials are expected to follow this study.

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Multiple congenital ocular defects in a Bedlington terrier dog (Bedlington terrier의 다발성 안기형 1례)

  • Yoo, Sukjong;Ji, Dongbeom;Kim, Hwiyool;Seo, Kangmoon;Jeong, Manbok
    • Korean Journal of Veterinary Research
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    • v.53 no.2
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    • pp.133-136
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    • 2013
  • To report multiple congenital ocular defects in a Bedlington terrier dog aged 2.5 months with blindness. Routine ophthalmic examinations were performed for the clinical signs. Menace responses and cotton ball test were absent in both eyes (OU), but pupillary light reflexes were normal in OU. Slit lamp biomicroscopy reveled corneal dystrophy, posterior subcapsular cataract, microphthalmia in OU and lenticular coloboma in the right eye. In indirect ophthalmoscopy and ultrasonography, retinal detachment and posterior lenticonus were shown in OU. It is the first report of lenticular coloboma and posterior lenticonus in a Bedlington terrier dog.