• Title/Summary/Keyword: noninvasive glucose sensor

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Development of an Portable Urine Glucose Monitoring System (휴대용 뇨당 측정 시스템의 개발)

  • 박호동;이경중;윤형로
    • Journal of Biomedical Engineering Research
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    • v.23 no.5
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    • pp.397-403
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    • 2002
  • Urine glucose monitoring system is a self-monitoring system that display the glucose level by non-invasive measurement method. In this paper, We developed a noninvasive urine glucose monitoring system that improved defects of urine glucose measurement with a colorimeter method and invasive blood glucose measurement method. This system consist of bio-chemical sensor for urine glucose measurements, signal detecting part, digital and signal analysis part, display part and power supplying part. The developed bio-chemical sensor for the measurement of urine glucose has good reproducibility, convenience of handing and can be mass-produced with cheap price. To evaluate the performance of the developed system, We performed the evaluation of confidence about the detection of glucose level by a comparison between a standard instrument in measuring glucose level and the developed system using standard glucose solutions mixed with urine. Standard error was 2.85282 from the evaluation of confidence based on regression analysis. Also, In analysis of S.D(standard deviation) and C.V(coefficient of validation) that are important parameters to evaluate system using bio-chemical sensor, S.D was 10% which falls under clinically valid value, 15%, and C.V was under 5%. Consequently from the above results, compared to blood glucose measurement, the system performance is satisfactory.

Noninvasive Method to Distinguish between Glucose and Sodium Chloride Solution Using Complementary Split-Ring Resonator (Complementary Split Ring Resonator(CSRR)를 이용한 포도당과 염화나트륨 수용액의 비침습적 구별)

  • Jang, Chorom;Park, Jin-Kwan;Yun, Gi-Ho;Yook, Jong-Gwan
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.29 no.4
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    • pp.247-255
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    • 2018
  • In this work, glucose solution and sodium chloride solution were distinguished noninvasively using a microwave complementary split-ring resonator (CSRR). Based on the electrical properties of the two solutions measured using a open-ended coaxial probe, a CSRR was designed and fabricated for operation at a specific frequency that facilitates differentiating the two solutions. Furthermore, a polydimethylsiloxane mold was fabricated to concentrate the solution at a region where the electric field of the resonator was strongest, and a laminating film was used to prevent contact between the solution and resonator. Experiments were performed by dropping $50{\mu}L$ of the solution in steps of 100 mg/dL up to a maximum human blood glucose level of 400 mg/dL. Our experiments confirmed that the transmission coefficients ($S_{21}$) of glucose solution and sodium chloride solution exhibit variations of -0.06 dB and 0.14 dB, respectively, per 100 mg/dL concentration change at the resonance frequency. Thus, the opposite trends in the variation of $S_{21}$ with change in the concentration of the two solutions can be used to distinguish between them.