• Nuclear Engineering and Technology
• /
• v.52 no.12
• /
• pp.2887-2900
• /
• 2020

Cladding failure in a fuel rod during operation in a BWR is analyzed using a FALCON code-based model. Comparative calculation with a neighbouring, intact rod is presented, as well. A considerable 'hot spot' effect in cladding temperature is predicted with the SLICE-DO model due to a thermal barrier caused by the localized crud deposition. Particularly significant overheating is expected to occur on the affected side of the cladding of the failed rod, in agreement with signs of significant localized crud deposition as revealed by Post Irradiation Examination. Different possibilities (criteria) are checked, and Pellet-Cladding Mechanical Interaction (PCMI) is shown to be one of the plausible potential threats. It is shown that PCMI could lead to discernible concentrated inelastic deformation in the overheated part of the cladding. None of the specific mechanisms considered can be experimentally or analytically identified as an only cause of the rod failure. However, according to the current calculation, a possibility of cladding failure by PCMI cannot be excluded if the crud thickness exceeded 300 ㎛.

• Korean Journal of Radiology
• /
• v.21 no.10
• /
• pp.1126-1137
• /
• 2020

Imaging plays a key role in the management of brain tumors, including the diagnosis, prognosis, and treatment response assessment. Radiomics and deep learning approaches, along with various advanced physiologic imaging parameters, hold great potential for aiding radiological assessments in neuro-oncology. The ongoing development of new technology needs to be validated in clinical trials and incorporated into the clinical workflow. However, none of the potential neuro-oncological applications for radiomics and deep learning has yet been realized in clinical practice. In this review, we summarize the current applications of radiomics and deep learning in neuro-oncology and discuss challenges in relation to evidence-based medicine and reporting guidelines, as well as potential applications in clinical workflows and routine clinical practice.

• Structural Engineering and Mechanics
• /
• v.90 no.3
• /
• pp.301-311
• /
• 2024

Different methods have been proposed in the literature for splicing the reinforcing bars in the construction of concrete structures, which are alternatively used depending on design requirements. The most common approach is the lap splicing which is known as a cost-effective method although, its main disadvantages including congestion of bars at the lap zone and consequently, material wastage has motivated utilization of the other techniques such as mechanical splices (couplers). To better evaluate the performance of the couplers, 6 reinforced concrete (RC) beams whose difference is only the type and location of splices have been experimentally studied in this paper. Based on the results, the mechanical connection of the bars did not markedly affect the load-carrying capacity of the specimens. Moreover, it was observed that after applying the loads and failure of the specimens, none of the bars ruptured at the splice location and all couplers remained undamaged.

• Journal of Microbiology and Biotechnology
• /
• v.29 no.3
• /
• pp.454-464
• /
• 2019

Salmonellosis is a highly contagious bacterial disease that threatens both human and poultry health. Tests that can detect Salmonella in the field are urgently required to facilitate disease control and for epidemiological investigations. Here, we combined loop-mediated isothermal amplification (LAMP) with a chromatographic lateral flow dipstick (LFD) to rapidly and accurately detect Salmonella. LAMP primers were designed to target the Salmonella invA gene. LAMP conditions were optimized by adjusting the ratio of inner to outer primers, $MgSO_4$ concentration, dNTP mix concentration, amplification temperature, and amplification time. We evaluated the specificity of our novel LAMP-LFD method using six Salmonella species and six related non-Salmonella strains. All six of the Salmonella strains, but none of the non-Salmonella strains, were amplified. LAMP-LFD was sensitive enough to detect concentrations of Salmonella enterica subsp. enterica serovar Pullorum genomic DNA as low as $89fg/{\mu}l$, which is 1,000 times more sensitive than conventional PCR. When artificially contaminated feed samples were analyzed, LAMP-LFD was also more sensitive than PCR. Finally, LAMP-LFD gave no false positives across 350 chicken anal swabs. Therefore, our novel LAMP-LFD assay was highly sensitive, specific, convenient, and fast, making it a valuable tool for the early diagnosis and monitoring of Salmonella infection in chickens.

• Journal of Ginseng Research
• /
• v.35 no.1
• /
• pp.39-44
• /
• 2011

We studied the acute oral toxicity of black ginseng (BG) produced by heat process in rats. Single acute BG extract doses of 0, 5, 10, and 15 g/kg dissolved in saline were administered by oral gavage and the animals were kept under observation for 14 days. The single administration of BG extract up to 15 g/kg did not produce mortality, behavioral change or abnormal clinical signs in the rats. These results indicated that the oral $LD_{50}$ of the BG extract in the rats is higher than 15 g/kg. Compared to the control group, no treatment-related biologically significant effects of BG extract were noted in the measurements of the body weight or food intake. At the end of the period, the biochemical parameters and hematological parameters were analyzed in the plasma and blood. A histopathological examination of the liver and kidney was also conducted. Only the blood nitrogen urea and potassium levels in the biochemical indices showed significant differences at 10 and 15 g/kg doses of BG extract compared to the control group. These changes were not considered to be due to the toxicity. None of the other clinical chemistry parameters were affected. Therefore, these results indicate that the BG by heat processing is virtually nontoxic.

• The Plant Pathology Journal
• /
• v.20 no.3
• /
• pp.184-191
• /
• 2004

Methanol extracts of fresh materials of 57 plants were screened for in vivo antifungal activity against Magna-porthe grisea, Corticium sasaki, Botrytis cinerea, Phyto-phthora infestans, Puccinia recondita, and Blumeria graminis f. sp. hordei. Among them, seven plant extracts showed disease-control efficacy of more than 90％ against at least one of six plant diseases. None of the plant extracts was highly active against tomato gray mold. The methanol extracts of Chloranthus japonicus (roots) (CjR) and Paulownia coreana (stems) (PcS) displayed the highest antifungal activity; the CjR extract controlled the development of rice blast, rice sheath blight, and wheat leaf rust more than 90％, and tomato gray mold and tomato late blight more than 80％. The PcS extract displayed control values of more than 90 ％ against rice blast, wheat leaf rust, and barley powdery mildew and more than 80％ against tomato gray mold. The extract of PcS also had a curative activity against rice sheath blight and that of CjR had a little curative activity against rice blast. On the other hand, the extract of Rumex acetocella roots reduced specifically the development of barley powdery mildew. Further studies on the characterization of antifungal substances in antifungal plant extracts are underway and their disease-control efficacy should be examined under greenhouse and field conditions.

• Food Science of Animal Resources
• /
• v.43 no.3
• /
• pp.471-490
• /
• 2023

In this study, the duck eggs were salted with none or 2.5% and 5.0% (v/v) of liquid smoke (LS), respectively. As a control, samples salted without LS were used. The 2-thiobarbituric acid (TBA) values, 1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging ability, and reducing power of the three groups were tested at 0, 7, 14, and 21 and 28 days to determine the effects of LS on the antioxidant activity of treated eggs. In addition, gas chromatography-mass spectrometry (GC-MS) and electronic nose (E-Nose) were used to analyze the volatile flavor components of fresh duck eggs, LS, control, and salted duck eggs enriched with 2.5% (v/v) LS after 28 days of salting. The TBA value considerably increased with an increase in salting period, and the treated egg's TBA value significantly associated with LS concentration. The TBA value decreased as the LS concentration increased. The amount of LS present was highly associated with their capacity to scavenge DPPH radicals. The reducing power of the samples was substantially correlated with the LS concentration, and the reducing power increased with increasing LS concentration. The GC-MS data revealed that phenols and ketones were the predominant chemicals present in the LS, and they were also found in the eggs added to the LS even though they were absent in the fresh eggs and control. The flavor of the control group and treated eggs with LS differed significantly, according to the principal component analysis and radar map of the E-nose. The texture study results revealed that the LS significantly impacted the hardness, cohesiveness, and chewiness of eggs.

• The Journal of Korea Robotics Society
• /
• v.3 no.4
• /
• pp.345-350
• /
• 2008

This study aims to propose the concept design of oil spill protection robot which can rapidly intervene to control the oil spillage situation at the sea. Taking into account the fact that a huge amount of oil is transported trans-continentally by oil tanker, none of industrialized countries are completely safe from the marine oil spill which results in social, economical and ecological damages to their communities. The employment of double hull-oil tanker, pipe line transporting can be most safe way. Yet complete prevention of oil spill is probably not realistic. Accordingly the alternative solution to control marine oil spill and minimize the damages caused by the incident using intelligent robot technology based on swarm control method is proposed. The main features of oil spill protection(OSP) robot is explained via following three perspectives. Firstly, from functional point of view, OSP robot system safely and efficiently replaces oil boom installation manually conducted by human workers with intelligent robot technology based on swarm control theory. For second, its modular architecture brings efficient storage of main components including oil boom and facilitates maintenance. For the last, its geometric form and shape enables whole system to be installed to helicopter, boat or oil tanker itself with ease and to rapidly deploy the units to the oil spill area.

• Structural Engineering and Mechanics
• /
• v.58 no.3
• /
• pp.475-514
• /
• 2016

Various models have been proposed by several researchers for predicting the exterior RC beam-column joint shear strength. Most of these models were calibrated and verified with some limited experimental database. From the models it has been identified that the joint shear strength majorly depends on ten governing parameters. In the present paper, detailed investigation of twelve analytical models for predicting shear strength of exterior beam-column joint has been carried out. The study shows the effect of each governing parameter on joint shear strength predicted by various models. It has been observed that the consensus on effect of few of the governing parameters amongst the considered analytical models has not been attained. Moreover, the predicted joint strength by different models varies significantly. Further, the prediction of joint shear strength by these analytical models has also been compared with a set of 200 experimental results from the literature. It has been observed that none of the twelve models are capable of predicting joint shear strength with sufficient accuracy for the complete range of experimental results. The research community has to reconsider the effect of each parameters based on larger set of test results and new improved analytical models should be proposed.

• Food Science and Biotechnology
• /
• v.16 no.3
• /
• pp.404-408
• /
• 2007

In this study, we investigated the effects by age of long-tenn supplementation of Epimedium koreanum Nakai (EKN)-containing water on the in vivo antioxidant capacities of rats. All rats were reared in a conventional system, and none of the rats showed any signs of aversion to the EKN solution. Neither the mean nor maximum life spans of the rats were extended by long-tenn administration of the solution. The EKN extract caused decreases in the levels of serum thiobarbituric acid reactive substances in the rats. The activities of superoxide dismutase, catalase, and glutathione (GSH) peroxidase within the liver cytosol decreased with age in both the control and EKN-supplemented groups. GSH peroxidase activity, however, was higher at old age in the EKN-supplemented group. The activities of GSH reductase and GSH-S-transferase, and the levels of free-sulfhydryl (SH) and total-SH group gradually decreased with age in both groups. However, there was some tendency for higher levels in the EKN supplemented group at a corresponding age. These results indicate that long-tenn supplementation of EKN water extracts alone does not exhibit discernible adverse effects in rats, and has some enhancing effects on the antioxidant capacities of the blood and liver, but it does not have life-prolonging effects.