• Title/Summary/Keyword: non-thermal DBD plasma

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Preferential Killing of Human Lung Cancer Cell Lines with Mitochondrial Dysfunction by Non-Thermal Dbd Plasma

  • Panngom, Kamonporn;Baik, Ku Youn;Nam, Min-Kyung;Rhim, Hyang-Shuk;Choi, Eun Ha
    • Proceedings of the Korean Vacuum Society Conference
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    • 2013.02a
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    • pp.199-199
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    • 2013
  • The distinctive cellular and mitochondrial dysfunctions of a human epithelial lung cancer cell line (H460) from a human lung fibroblastic normal cell line (MRC5) have been studied by dielectric barrier discharge (DBD) plasma treatment. The DBD plasma device have generated large amount of H2O2 and NOx in culture media which is dependent on plasma exposure time. It is found that the cell number of lung cancer cell H460 has been reduced more than the lung normal cell MRC5 as being increased exposure and incubation time. Also these both cell lines have showed mitochondria fragmentation under 5 minutes' plasma exposure, which is a clue of apoptosis. It is noted in this study that AnnexinV staining has showed not only early apoptosis, but also late apoptosis in lung cancer cell H460. Mitochondria enzyme activity and ATP generation have been also much reduced in lung cancer cell H460. Their mitochondrial membrane potential (${\Delta}{\psi}m$) has been found to be reduced in magnitude and shifted to the induced-potential level of cccp, while MRC5 mitochondrial membrane potential has been shifted slightly to that. These distinctively selective responses of lung cancer cell H460 from lung normal cell MRC5 gives us possibility of applying plasma to cancer therapy.

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Decomposition of Acetonitrile by Planar Type Dielectric Barrier Discharge Reactor (평판형 유전체 장벽 방전 반응기에서 Acetonitrile의 분해 특성)

  • 송영훈;김관태;류삼곤;이해완
    • Journal of the Korea Institute of Military Science and Technology
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    • v.5 no.3
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    • pp.105-112
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    • 2002
  • A combined process of non-thermal plasma and catalytic techniques has been investigated to treat toxic gas compounds in air. The treated gas in the present study is $CH_3$CN that has been known to be a simulant of toxic chemical agent. A planar type dielectric barrier discharge(DBD) reactor has been used to generate non-thermal plasma that produces various chemically active species, O, N, OH, $O_3$, ion, electrons, etc. Several different types of adsorbents and catalysts, which are MS 5A, MS 13X, Pt/alumina, are packed into the plasma reactor, and have been tested to save power consumption and to treat by-products. Various aspects of the present techniques, which are decomposition efficiencies along with the power consumption, by-product analysis, reaction pathways modified by the adsorbents and catalysts, have been discussed in the present study.

Characteristics of $CH_4$ Decomposition by Plasma (플라즈마 이용 메탄 분해 특성)

  • Kim, Kwan-Tae;Lee, Dae-Hoon;Cha, Min-Suk;Ryu, Jeong-In;Song, Young-Hoon
    • Journal of the Korean Society of Combustion
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    • v.10 no.4
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    • pp.24-32
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    • 2005
  • Various types of plasma source applied in $CH_4$ decomposition process are compared. DBD by pulse and AC power, spark by pulse and AC power, rotating arc and hollow cathode plasma are chosen to be compared. The results show that $CH_4$ conversion per given unit power is relatively high in hollow cathode plasma and rotating arc that induces rather high temperature condition and that is why both thermal dehydration and plasma induced decomposition contribute for the overall process. In case of DBD wherein high temperature electron and low temperature gas molecule coexist, the process shows low conversion rate, for in rather low temperature condition the contribution of thermal dehydration is lowered. Selectivity of $C_2H_6$ and $C_2H_2$ is shown to be a good parameter of the relative contribution of plasma chemistry in the overall process. From the results we concluded that required condition of plasma source for a cost effective and high yield $CH_4$ decomposition is to have characteristics of both thermal plasma and non thermal plasma in which temperature is high above a certain threshold state for thermal dehydration and electron induced collision is maximized in the same breath.

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Antifungal Activity of Non-thermal Dielectric Barrier Discharge Plasma Against Clinical Isolates of Dermatophytes

  • Ali, Anser;Hong, Young June;Lee, SeungHyun;Choi, Eun Ha;Park, Bong Joo
    • Proceedings of the Korean Vacuum Society Conference
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    • 2014.02a
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    • pp.260-260
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    • 2014
  • Dermatophytes can invade in keratinized tissues and cause dermatophytosis [1] that rank among the most widespread and common infectious diseases world-wide. Although several systemically and topically administered drugs with activities against these fungi are available, still complete eradication of some of these infections, is difficult and relapses and remissions are often observed [2,3]. In addition, some people are allergic to many of the available drugs which add complications even more. Therefore, the search for novel, selective and more effective therapy is always required and it may help the clinicians to choose the correct treatment for their patients. Non-thermal plasmas primarily generate reactive species and recently have emerged as an efficient tool for medical applications including sterilization. In this study, we evaluated the ability of non-thermal dielectric barrier discharge (DBD) plasma for the inactivation of clinical isolates of Trichophyton genera, Trichophyton mentagrophytes (T. mentagrophytes) and Trichophyton rubrum (T. rubrum), which cause infections of nails and skin and, are two of the most frequently isolated dermatophytes [4]. Our results showed that DBD plasma has considerable time dependent inactivation potential on both T. mentagrophytes and T. rubrum in-vitro. Furthermore, the mechanisms for plasma based T. mentagrophytes and T. rubrum inactivation and planning for in-vivo future studies will be discussed.

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Removal of Styrene Using Different Types of Non-Thermal Plasma Reactors (저온플라즈마 반응기의 형태에 따른 스타이렌 분해 특성에 관한 연구)

  • Park, Jeong-Uk;Choi, Kum-Chan;Kim, Hyun-Ha;Ogata, Atsushi;Futamura, Shigeru
    • Journal of Korean Society of Environmental Engineers
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    • v.27 no.2
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    • pp.215-223
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    • 2005
  • Non-thermal plasma decomposition of gas-phase styrene was investigated in this study using three different types of plasma reactors; dielectric-barrier discharge (DBD) reactor, surface discharge (SD) reactor and plasma-driven catalyst (PDC) reactor packed with 2.0 wt% $Ag/TiO_2$ catalysts. The main parameters used for the comparative assessment of the plasma reactors include the decomposition efficiency, carbon balance, byproduct distribution, COx ($CO+CO_2$) selectivity and COx yield. The SD and the DBD reactors showed better conversion efficiency of styrene than that of the PDC reactor due to their larger capability in ozone formation. On the other hand, the PDC reactor showed better carbon balance, the yield and the selectivity of COx. The required specific input energies to achieve 100% carbon balance from the decomposition of 100 ppmv styrene using the plasma alone reactors and the PDC reactor were 420 J/L and 110 J/L, respectively. The major decomposition products in gas-phase were CO, $CO_2$ and HCOOH regardless of the types of plasma reactors. In the case of SD and DBD reactors, the $CO_2$ selectivity ranged in $39.5{\sim}60%$. The $CO_2$ selectivity in the PDC reactor was in range of $68.5{\sim}75.5%$.

Interaction between a Flame and a Non-thermal Plasma (화염과 저온플라즈마의 상호작용에 관한 연구)

  • Cha, Min-Suk;Lee, Sang-Min;Kim, Kwan-Tae;Chung, Suk-Ho
    • 한국연소학회:학술대회논문집
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    • 2002.06a
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    • pp.179-184
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    • 2002
  • Interaction between flames and non-thermal plasmas of DBD type has been experimentally investigated. Vigorous streamers were observed under flame conditions because of the increase of reduced field (electrical) at high temperature as well as the seeding of free electrons and ions generated inside the flame. Flame lengths were significantly shortened as the applied voltage increased on account of intense mixing by ionic winds and soot-induced flows. Flame luminosities severely decreased under plasma conditions, which means the reduction of soot, since the residence time was reduced because of the flame shortening. Temperature and major species concentrations measured by FTIR were not changed despite the plasma generation. which shows overall chemistries were not affected by non-thermal plasmas.

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Oxidation of Elemental Mercury using Dielectric Barrier Discharge Process (유전체 장벽 방전을 이용한 원소수은의 산화특성)

  • Byun, Youngchul;Ko, Kyung Bo;Cho, Moo Hyun;NamKung, Won;Shin, Dong Nam;Koh, Dong Jun;Kim, Kyoung Tae
    • Korean Chemical Engineering Research
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    • v.45 no.2
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    • pp.183-189
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    • 2007
  • We have investigated the oxidation of gas phase elemental mercury using dielectric barrier discharge (DBD). In the DBD process, active species such as $O_3$, OH, O and $HO_2$ are generated by collisions between electrons and gas molecules. Search active species convert elemental mercury into mercury oxide which is deposited into the wall of DBD reactor because of its low vapor pressure. The oxidation efficiency of elemental mercury has been decreased from 60 to 30% by increasing the initial concentration of the elemental mercury from 72 to $655{\mu}g/Nm^3$. The gas retention time at the DBD reactor has showed the little effect on the oxidation efficiency. The more oxygen concentration has induced the more oxidation of elemental mercury, whereas there has been no appreciable oxidation within pure $N_2$ discharge. It has indicated that oxygen atom and ozone, generated in air condition determine the oxidation of elemental mercury.

Comparative Studies on Soot Oxidation by Nitrogen Dioxide and Ozone

  • Purushothama, C.;Chen, Xin-Hong;Li, Ming-Wei;Chae, Jae-Ou;Sim, Ju-Hyen
    • 한국연소학회:학술대회논문집
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    • 2006.10a
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    • pp.117-121
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    • 2006
  • Non-thermal plasma technology has many applications in various areas. One of the applications is regenerating diesel particulate filter (DPF). DPF is a widely applied device to control the particulate emission of diesel engines. But it needs periodic removal of clogged soot for the smooth running of engine. Conventional high-temperature removal processes easily leads to the breakage of DPF. Herein, low-temperature plasma formed in a dielectric barrier discharge (DBD) reactor was used to form active oxidants such as ozone and nitrogen dioxide. Experimentally, the effects of discharge power and frequency on the performance of DBD reactor were studied. Two oxidants, $O_3$ and $NO_2$, were synthesized and used for incinerating soot in the used DPF. Performances of the two oxidants on the reduction of soot were compared, and it was found that $NO_2$ is more effective than $O_3$ for getting rid of soot

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Non-thermal plasma technology for abatement of pollutant emission from marine diesel engine

  • Panomsuwan, Gasidit;Rujiravanit, Ratana;Ueno, Tomonaga;Saito, Nagahiro
    • Journal of Advanced Marine Engineering and Technology
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    • v.40 no.10
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    • pp.929-934
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    • 2016
  • Plasma technology has long been regarded as a key essential tool in many industrial and technological sectors. However, the advancement of plasma technology in marine applications has not been fully realized yet. Herein, we present a short overview on the recent trends in utilization of plasma technology for air-pollution treatment in marine diesel exhaust. Four non-thermal plasma system, including electron beam dry scrubber (EBDS), dielectric barrier discharge (DBD), electron beam-microwave (EB-MW) plasma hybrid system, and plasma-catalytic hybrid system, are described with emphasis on their efficiency in removals of $NO_x$ and $SO_x$ gases. Non-thermal plasma has the great potential to be an efficient and environmentally compatible technique in simultaneous removals of $NO_x$ and $SO_x$ gases from the exhaust of marine diesel engine in the future.

A Study on the Dielectric Barrier Discharges Plasmas of Flat Atmospheric Pressure Using an AC Pulse Voltage (교류 펄스 전압을 이용한 평판형 대기압 유전격벽방전 플라즈마의 특성 분석)

  • Lee, Jong-Bong;Ha, Chang-Seung;Kim, Dong-Hyun;Lee, Ho-Jun;Lee, Hae-June
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.61 no.5
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    • pp.717-720
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    • 2012
  • Various types of dielectric-barrier-discharge (DBD) devices have been developed for diverse applications for the last decade. In this study, a flat non-thermal DBD micro plasma source under atmospheric pressure has been developed. The flat-panel type plasma is generated by bipolar pulse voltages, and driving gas is air. In this study, the plasma source was investigated with intensified charge coupled device (ICCD) images and Optical Emission Spectroscopy (OES). The micro discharges are generated on the crossed electrodes. For theoretical analysis, 2-dimensional fluid simulation was performed. The plasma source can be driven in air, and thus the operation cost is low and the range of application is wide.