• 아태비즈니스연구
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• 제15권2호
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• pp.223-236
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• 2024

Purpose - The purpose of the paper is to empirically investigate the asymmetric adjustment of loan and deposit interest rates among banks and non-bank depository institutions. Design/methodology/approach - We construct a VAR model using time series data comprising loan and deposit interest rates of banks and non-bank depository institutions, along with the call rate. Based on this model, we conduct impulse-response analysis and variance decomposition to investigate the dynamic relationship between the interest rates. Findings - In the case of banks and credit unions, the responses of deposit rates to the call rate are larger than the responses of loan rates, and we cannot find evidence of non-linear responses. In the case of savings banks, the responses of loan rates to the call rate are larger than the responses of deposit rates. The responses of loan rates to a positive call rate shock are statistically significant, while the responses of loan rates to a negative call rate shock are not statistically significant. Research implications or Originality - This study differs from previous research in that it examines the asymmetric response of loan and deposit rates of both banks and non-bank financial institutions to changes in the call rate. The implications for the impact of these findings on the financial system and income inequality are presented.

• Asian Pacific Journal of Cancer Prevention
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• 제16권14호
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• pp.5963-5966
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• 2015

Background: This analysis was conducted to evaluate the efficacy and safety of a combination of gemcitabine and nedaplatin in treating patients with non-small cell lung cancer. Methods: Clinical studies evaluating the efficacy and safety of a combination of gemcitabine and nedaplatin with attention to response and safety for patients with non-small cell lung cancer were identified using a predefined search strategy. Pooled response rates for gemcitabine and nedaplatin were calculated. Results: In gemcitabine and nedaplatin based regimens, 4 clinical studies including 112 patients with non-small cell lung cancer were considered eligible for inclusion. The pooled analysis suggested that the pooled reponse rate was 40.2% (45/112). Main side effects included grade 3-4 neutropenia, thrombocytopenia, and anemia. Grade 3-4 nonhematological toxicity included nausea and vomiting, diarrhea, and hepatic dysfunction. There were no treatment-related deaths. Conclusion: This evidence based analysis suggests that the combination of gemcitabine and nedaplatin is associated with good response rate and accepted toxicity for treating patients with non-small cell lung cancer.

• 정신신체의학
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• 제31권1호
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• pp.19-24
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• 2023

Objectives : Biofeedback is a useful non-pharmacological treatment for panic disorder (PD), but no studies have identified physiological markers related to the treatment response. This study investigated predictors of the treatment response for biofeedback in patients with PD. Methods : A retrospective study based on the electronic medical records of 372 adult patients with PD was performed. Patients received biofeedback treatment at least once, and physiological markers including heart rate, heart rate variability, respiratory rate, skin conductance, skin temperature, and electromyography were collected before the treatment began. The patients were classified as responders or non-responders based on the change in Clinical Global Impression-Severity (CGI-S) score. Results : The response rate to biofeedback treatment was 30.4%. Multivariable logistic regression analysis revealed that a higher CGI-S score at baseline and fewer benzodiazepine prescriptions were associated with a better response to biofeedback treatment. According to subgroup analyses, the baseline CGI-S score, dose of benzodiazepines, and skin conductance are candidate predictors of the response to biofeedback treatment in men, while only baseline disease severity was associated with the treatment response in women. Conclusions : The present results suggest that skin conductance may be target marker and predictor for biofeedback in male patients with PD.

• 응용통계연구
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• 제33권4호
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• pp.409-420
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• 2020

사업체조사에서는 흔히 수정절사법이 사용되며 이 방법을 사용함으로써 표본의 수를 줄이면서도 추정의 정확성을 향상 시킬 수 있다. 그러나 전수층의 무응답률은 크게 높아지고 있으며 예비표본을 이용한 표본대체가 불가능하기 때문에 전수층에서 발생한 무응답은 추정의 정확성을 크게 떨어뜨리고 있다. 특히 무응답이 관심변수에 영향을 받는 경우에는 편향이 발생할 가능성이 매우 높기 때문에 이를 적절히 처리하는 것은 매우 중요하다. 본 연구에서는 전수층에서 발생한 무응답을 적절히 처리하는 방법의 하나로 편향보정 추정법을 제안하였다. 특히 Chung과 Shin(2020)에서 제안한 편향보정 추정량을 전수층 편향보정에 적용하였으며 전수층이라는 특수한 경우에 맞는 새로운 추정 방법을 제안하였다. 또한 모의실험을 통해 제안된 방법의 우수성을 살펴보았으며 실제 자료 분석을 실시하여 본 논문에서 제안한 방법의 우수성을 확인하였다.

• 응용통계연구
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• 제33권1호
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• pp.11-23
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• 2020

표본조사는 비용과 시간을 절약하면서도 주어진 정확성을 만족하는 통계를 얻을 수 있다. 그러나 최근에는 다수의 무응답 발생으로 인해 조사의 정확성이 크게 떨어지고 있다. 무응답은 다양한 이유로 발생하고 있으나 무응답이 관심변수와 함수 관계가 있는 경우에는 이 정보를 이용하여 무응답을 적절히 처리해야 추정의 정확성이 유지될 수 있다. 최근 Chung과 Shin (2017, 2019), Min과 Shin (2018)은 응답률이 관심변수의 지수 또는 선형함수이고 초모집단모형의 오차가 정규분포를 따를 때 무응답으로 인해 발생한 편향을 제거함으로써 추정의 정확성이 향상되는 것을 확인하였다. 이에 본 연구에서는 사업체조사에서 초모집단모형의 오차가 감마분포 또는 로그-정규분포를 따르는 경우에서의 무응답 편향보정 추정량을 제안하였다. 또한 모의실험을 통하여 제안된 추정량의 우수성을 확인하였다.

• 대한의생명과학회지
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• 제23권3호
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• pp.215-222
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• 2017

Obesity has been directly associated with the development of hypertension and cardiovascular disease. The purpose of this study was to investigate the blood pressure response during graded exercise test in obese adults. 189 subjects (age: $47.96{\pm}10.23$) were assigned to two groups: non-obese group (N=105, BMI: $22.05{\pm}1.57$, waist circumference: $76.90{\pm}6.17$) and obese group (N=84, BMI: $26.96{\pm}2.51$, waist circumference: $88.29{\pm}6.41$). The subjects underwent health screening and exercise treadmill test from January 2012 to December 2014. Graded exercise test was performed according to the Bruce protocol. Exercise duration (P=0.046) and METs (P=0.015) were significantly lower in obese group than non-obese group. There was no difference in the rate of change in blood pressure response between obese group and non-obese group during exercise, and the recovery rate of systolic blood pressure was delayed in the obese group compared to non-obese group in the first recovery period (P=0.020). The significant factors of increasing rate of change in maximum systolic blood pressure was waist (P=0.046) and hip circumference (P=0.008). In conclusion, these results demonstrate that, for hypertension prevention in obese adults, waist and hip circumference levels should be managed within normal range.

• 응용통계연구
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• 제32권4호
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• pp.631-642
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• 2019

다수의 항목무응답이 발생한 표본조사에서는 추정의 정확성이 떨어진다. 이를 해결하기 위한 많은 방법이 개발되었으나 응답률이 관심변수에 의해 영향을 받는 경우임에도 이를 고려하지 않고 랜덤으로 무응답이 발생한다는 가정 하에서 사용하는 무응답 처리 방법을 사용하게 되면 편향이 발생하는 것으로 알려져 있다. Chung과 Shin (2017)과 Min과 Shin (2018)은 응답률이 관심변수의 함수인 경우에서 발생된 편향을 적절히 처리하여 추정의 정확성을 향상시키는 방법을 제안하였다. 본 연구에서는 응답률 함수가 선형(linear)이면서 초모집단 모형의 오차가 정규분포를 따르는 경우를 살펴보았으며 층별 모집단 수가 편향 보정에 영향을 주는지도 살펴보았다. 모의실험을 통하여 제안된 추정량의 성능을 살펴보았으며 실제 자료 분석을 통해 이를 확인하였다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권11호
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• pp.4797-4800
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• 2015

Background: This analysis was conducted to evaluate the efficacy and safety of crizotinib based regimens in treating Chinese patients with EML4-ALK positive non-small-cell lung cancer. Materials and Methods: Clinical studies evaluating the efficacy and safety of crizotinib based regimens on response and safety for Chinese patients with EML4-ALK positive non-small-cell lung cancer were identified by using a predefined search strategy. Pooled response rate (RR) of treatment were calculated. Results: In crizotinib based regimens, 3 clinical studies which including 128 Chinese patients with EML4-ALK positive non-small-cell lung cancer and treated with crizotinib based regimen were considered eligible for inclusion. Pooled analysis suggested that, in all patients, the pooled RR was 59.3% (76/128) in crizotinib based regimens. ALT/AST mild visual disturbances, nausea, and vomiting were the main side effects. No treatment related death occurred in these crizotinib based treatments. Conclusions: This pooled analysis suggests that crizotinib based regimens are associated with good response rate and accepted toxicities in treating Chinese patients with EML4-ALK positive non-small-cell lung cancer.

• 응용통계연구
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• 제34권6호
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• pp.923-936
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• 2021

표본조사에서는 다수의 무응답이 발생하며 이를 적절히 처리하는 다양한 방법이 개발되었다. 특히 무응답이 관심변수에 영향을 받고 이로 인해 발생한 편향은 추정의 정확성을 크게 떨어뜨리며 무응답 처리를 어렵게 한다. 최근 Chung과 Shin (2017, 2020)은 알려진 모수적 초모집단 모형과 응답률 모형을 이용하여 추정의 정확성을 향상한 추정량을 제안하였다. 본 연구에서는 초모집단 모형의 형태를 일반화하여 비모수적 함수 형태를 설정한 후 이를 기반으로 얻어진 편향을 적절히 처리한 편향 보정 평균추정량을 제안하였다. 모의실험을 통해 본 연구에서 제안한 방법의 우수성을 확인하였다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권13호
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• pp.5521-5524
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• 2015

Purpose: This analysis was conducted to evaluate the efficacy and safety of icotinib based regimens in treating patients with non-small cell lung cancer (NSCLC). Methods: Clinical studies evaluating the efficacy and safety of icotinib-based regimens with regard to response and safety for patients with NSCLC were identified using a predefined search strategy. Pooled response rates of treatment were calculated. Results: With icotinib-based regimens, 7 clinical studies which including 5,985 Chinese patients with NSCLC were considered eligible for inclusion. The pooled analysis suggested that, in all patients, the positive reponse rate was 30.1% (1,803/5,985) with icotinib-based regimens. Mild skin itching, rashes and diarrhea were the main side effects. No grade III or IV renal or liver toxicity was observed. No treatment-related death occurred in patients treated with icotinib-based regimens. Conclusions: This evidence based analysis suggests that icotinib based regimens are associated with mild response rate and acceptable toxicity for treating Chinese patients with NSCLC.