• 제목/요약/키워드: non-destruction

검색결과 232건 처리시간 0.021초

전두동을 침습한 안와부 피부모양기형낭의 치험례 (A Clinical Experience of Direct Extension to Frontal Sinus of Orbital Dermoid Cyst)

  • 이상순;이형철
    • Archives of Plastic Surgery
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    • 제33권2호
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    • pp.252-254
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    • 2006
  • The dermoid cyst is the one of common space occupying orbital lesion. This lesion is regarded as a non-invasive tumor, but infrequently causes destruction of adjacent bony structure and displacement of adjacent tissue. We experienced a characteristic ovoid orbital dermoid cyst that occupied in the frontal sinus and causes displacement of the eyeball with well-defined lining. This 55-year-old male presented a mass in left orbit, which rapidly increased in size for past 12 months, and patient could not open left eyelid. We removed this tumor totally then reconstructed the orbital roof and frontal sinus with an iliac bone graft and polyethylene sheet(Medpor Newnan, USA). This patient was followed up for 12 months and patient obtained satisfactory result without any complication suck as recurrence or infection.

레이더법을 이용한 터널 배면 공동 영향특성 실험 (An Experimental Study for Void Lengths and Locations under Concrete Tunnel Lining using Radar Method)

  • 박석균;김대훈
    • 한국콘크리트학회:학술대회논문집
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    • 한국콘크리트학회 2005년도 봄학술 발표회 논문집(I)
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    • pp.363-366
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    • 2005
  • The radar method based non-destruction inspection stands in the spotlight of concrete tunnel lining due to the advantages of less restrictions of applicability, simpleness and quickness. However, in the case of utilizing at constructions, the decomposition ability is decreased because the effect of damping and dispersion is potent and the utilization of high frequency is difficult. In particular, it is very difficult to investigate the size and thickness of tunnel using the low frequency radar with low decomposition ability In this work, to resolve the above problems, the effect of arrangement between adjacent tunnels is investigated utilizing the low frequency radar and results are reported

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전자레인지용 LLC 공진형 인버터의 기동 제어 (Start-up Control of LLC Resonant Inverter for Microwave Oven Application)

  • 강계룡;김흥근;차헌녕
    • 전력전자학회논문지
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    • 제22권5호
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    • pp.463-468
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    • 2017
  • One of the most critical part for magnetron driving in microwave oven is start-up control. For this, switching frequency of resonant inverter should be carefully controlled in order to supply sufficient power to the filament of the magnetron and to prevent rectifier diode from destruction caused by the excessive voltage across them. This paper proposes a novel start-up control strategy for LLC resonant inverter for microwave oven considering the non-oscillation mode time and the magnetron voltage during the start-up process. The validity of the proposed method is verified through the experiment with 1,200W microwave oven using LLC resonant inverter.

Epigenetic Regulation of Chondrocyte Catabolism and Anabolism in Osteoarthritis

  • Kim, Hyeonkyeong;Kang, Donghyun;Cho, Yongsik;Kim, Jin-Hong
    • Molecules and Cells
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    • 제38권8호
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    • pp.677-684
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    • 2015
  • Osteoarthritis (OA) is one of the most prevalent forms of joint disorder, associated with a tremendous socioeconomic burden worldwide. Various non-genetic and lifestyle-related factors such as aging and obesity have been recognized as major risk factors for OA, underscoring the potential role for epigenetic regulation in the pathogenesis of the disease. OA-associated epigenetic aberrations have been noted at the level of DNA methylation and histone modification in chondrocytes. These epigenetic regulations are implicated in driving an imbalance between the expression of catabolic and anabolic factors, leading eventually to osteoarthritic cartilage destruction. Cellular senescence and metabolic abnormalities driven by OA-associated risk factors appear to accompany epigenetic drifts in chondrocytes. Notably, molecular events associated with metabolic disorders influence epigenetic regulation in chondrocytes, supporting the notion that OA is a metabolic disease. Here, we review accumulating evidence supporting a role for epigenetics in the regulation of cartilage homeostasis and OA pathogenesis.

Destruction of 2-Chloriphenol from Wastewater and Investigation of By-products by Ozonation

  • 정오진
    • Bulletin of the Korean Chemical Society
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    • 제22권8호
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    • pp.850-856
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    • 2001
  • This study investigates the ozonation kinetics of 2-chlorophenol in wastewater under acidic condition. Intermediates and by-products generated during the process were rigorously identified and quantified. The major by-products are four carboxylic acids: tartaric acid, oxalic acid, maleic acid, and hydroxymalonic acid. The generation of these organic acids is in agreement with theoretical predictions. But hydroxylated compounds are more favorable to produce than their corresponding non-hydroxylated ones. Based on the information concerning the generation of organic acids and other aromatic intermediates, the complete reaction pathways toward mineralization can be proposed and mathematically modeled. The fitted second-order rate constants are in the same order of magnitude with the results from other studies. Using these oxidation pathways and the corresponding kinetic model, by-products generated in ozonation process can be predicted. This can help in optimizing the design and operation of any subsequent treatment processes.

A new design method for site-joints of the tower crane mast by non-linear FEM analysis

  • Ushio, Yoshitaka;Saruwatari, Tomoharu;Nagano, Yasuyuki
    • Advances in Computational Design
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    • 제4권4호
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    • pp.343-365
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    • 2019
  • Among the themes related to earthquake countermeasures at construction sites, those for tower cranes are particularly important. An accident involving the collapse of a crane during the construction of a skyscraper has serious consequences, such as human injury or death, enormous repair costs, and significant delays in construction. One of the causes of deadly tower crane collapses is the destruction of the site joints of the tower crane mast. This paper proposes a new design method by static elastoplastic finite element analysis using a supercomputer for the design of the end plate-type tensile bolted joints, which are generally applied to the site joints of a tower crane mast. This new design method not only enables highly accurate and reliable joint design but also allows for a design that considers construction conditions, such as the introduction of a pre-tension axial force on the bolts. By applying this new design method, the earthquake resistance of tower cranes will undoubtedly be improved.

An accurate diagnosis of odontogenic cutaneous sinus tract by different computed tomography unit setting

  • Sodnom-Ish, Buyanbileg;Eo, Mi Young;Kim, Soung Min
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • 제47권1호
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    • pp.51-56
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    • 2021
  • Due to their rarity and the lack of associated dental symptoms, odontogenic cutaneous sinus tracts (OCSTs) are often misdiagnosed and confused with cutaneous lesions or non-odontogenic infections. It has been estimated that 50% of individuals affected by OCSTs are subjected to inappropriate treatments before the correct diagnosis is established. We describe the diagnosis and treatment of two cases of OCSTs. By using a computed tomography (CT) with soft tissue window setting, the extent of cortical bone destruction and the path of the sinus tract in the soft tissue was easily identified. Thus, we recommend the use of imaging techniques such as CT, which can confirm the odontogenic origin and the exact location of the OCST.

SOLUTIONS OF A CLASS OF COUPLED SYSTEMS OF FUZZY DELAY DIFFERENTIAL EQUATIONS

  • Wu, Yu-ting;Lan, Heng-you;Zhang, Fan
    • Nonlinear Functional Analysis and Applications
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    • 제26권3호
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    • pp.513-530
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    • 2021
  • The purpose of this paper is to introduce and study a class of coupled systems of fuzzy delay differential equations involving fuzzy initial values and fuzzy source functions of triangular type. We assume that these initial values and source functions are triangular fuzzy functions and define solutions of the coupled systems as a triangular fuzzy function matrix consisting of real functional matrices. The method of triangular fuzzy function, fractional steps and fuzzy terms separation are used to solve the problems. Furthermore, we prove existence and uniqueness of solution for the considered systems, and then a solution algorithm is proposed. Finally, we present an example to illustrate our main results and give some work that can be done later.

방수층에 전달되는 진동 요구응답스펙트럼을 재해석 한 성능평가 시험장치 개발에 관한 연구 (A study on the development of a performance evaluation test apparatus for reinterpreting the vibration demand response spectrum for waterproof layers)

  • 김수연;이승진;오상근
    • 한국건축시공학회:학술대회논문집
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    • 한국건축시공학회 2021년도 가을 학술논문 발표대회
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    • pp.208-209
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    • 2021
  • In 2017, 100 aftershocks with a magnitude of 2.0~3.0 and 615 minor earthquakes in Pohang in Korea caused the collapse and destruction of aggregate, tile, glass, and other structural components of multi-family houses constructed as finishing materials for buildings, causing damage to vehicles and casualties. Based on this factor, seismic design standards were established for non-structural elements of buildings that were applied only to past structures. Therefore, this study reinterpreted various vibration response spectra transmitted to waterproof layers as well as the definition and concept of the waterproof layer demand response spectrum derived by developing various vibration response test evaluation devices through a new testing apparatus.

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Ultrasound Targeted Microbubble Destruction for Novel Dual Targeting of HSP72 and HSC70 in Prostate Cancer

  • Wang, Hang-Hui;Song, Yi-Xin;Bai, Min;Jin, Li-Fang;Gu, Ji-Ying;Su, Yi-Jin;Liu, Long;Jia, Chao;Du, Lian-Fang
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권3호
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    • pp.1285-1290
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    • 2014
  • The aim was to determine whether ultrasound targeted microbubble destruction (UTMD) promotes dual targeting of HSP72 and HSC70 for therapy of castration-resistant prostate cancer (CRPC), to improve the specific and efficient delivery of siRNA, to induce tumor cell specific apoptosis, and to find new therapeutic targets specific of CRPC.VCaP cells were transfected with siRNA oligonucleotides. HSP70, HSP90 and cleaved caspase-3 expression were determined by real-time quantitative polymerase chain reaction and Western blotting. Apoptosis and transfection efficiency were assessed by flow cytometry. Cell viability assays were used to evaluate safety. We found HSP72, HSC70 and HSP90 expression to be absent or weak in normal prostate epithelial cells (RWPE-1), but uniformly strong in prostate cancerous cells (VCaP). UTMD combined with dual targeting of HSP72 and HSC70 siRNA improve the efficiency of transfection, cell uptake of siRNA, downregulation of HSP70 and HSP90 expression in VCaP cells at the mRNA and protein level, and induction of extensive tumor-specific apoptosis. Cell counting kit-8 assays showed decreased cellular viability in the HSP72/HSC70-siRNA silenced group. These results suggest that the combination of UTMD with dual targeting HSP70 therapy for PCa may be most efficacious, providng a novel, reliable, non-invasive, safe targeted approach to improve the specific and efficient delivery of siRNA, and achieve maximal effects.