• Parasites, Hosts and Diseases
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• v.57 no.5
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• pp.505-511
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• 2019

Acanthamoeba keratitis (AK) is a rare sight-threatening corneal infection, often reporting from contact lens wearers. An asymptomatic human immunodeficiency virus (HIV)-infected Thai male without history of contact lens use complained foreign body sensation at his left eye during motorbike riding. He had neither specific keratitis symptoms nor common drugs responding, which contributed to delayed diagnosis. By corneal re-scraping, Acanthamoeba-like cysts were detected by calcofluor white staining and agar culture. The etiological agent obtained from the culture was molecularly confirmed by Acanthamoeba spp.-specific PCR, followed by DNA sequencing. The results from BLAST and phylogenetic analysis based on the DNA sequences, revealed that the pathogen was Acanthamoeba T4, the major genotype most frequently reported from clinical isolates. The infection was successfully treated with polyhexamethylene biguanide resulting in corneal scar. This appears the first reported AK case from a non-contact lens wearer with HIV infection in Thailand. Although AK is sporadic in developing countries, a role of free-living Acanthamoeba as an opportunistic pathogen should not be neglected. The report would increase awareness of AK, especially in the case presenting unspecific keratitis symptoms without clinical response to empirical antimicrobial therapy.

• Journal of Korean Ophthalmic Optics Society
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• v.17 no.4
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• pp.403-410
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• 2012

Purpose: The purposes of this study are to investigate accommodative response among emmetropes, spectacle wearer and contact lens wearer, and correlation between refractive error and accommodative respons for each group. Methods: The 72 subjects(144 eyes) who do not have any ocular diseases were participate in this study. Subjects were categorized into emmetropes, spectacle wearer and contact lens wearer by refractive error using closed-field auto-refractometer. We measured dominant eye, naked/habitual visual acuity and refractive error of monocular/binocular vision of refractive error for far/near distance with open-field auto-refractometer and calculated accommodative lag. Results: There were no significant difference of accommodative lag between right and left eye dominant and non-dominant eye, monocular and binocular vision, and spectacle lens wearer and contact lens wearer, However the accommodative lag of binocular vision was severe than monocular vision at near. The lag of myopia was larger than emmetropes, and male was larger than female. Significant correlation was found between refractive error and accommodative lag in total subjects and the same result was found in emmetropes and contact lens wearer. However there were no significant correlation in the spectacle wearer. Conclusions: There were significant difference between emmetrops and myopes in terms of accommodative lag, however accommodative lag of spectacle wearer was not different with contact lens wearer in myopes. There were also significant correlation between refractive error and accommodative lag in emmetropes and contact lens wearer, but the accommodative lag of spectacle wearer was not significantly correlated with refractive error.

• Journal of Korean Ophthalmic Optics Society
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• v.3 no.1
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• pp.249-258
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• 1998

This study was researched the state and problem of the soft contact Lens wear by the history and inverted microscopy. The results was as follows; 1. The first use of contact lens wear was the 15 years and the last use was the 26 years. The first age of most contact lens wear was the 19 years. 2. In the almost contact lens wearers, the first visual test was the optical shop. 3. At present, almost soft contact lens purchase the optical shop 4. At present, most contact lens wearer like a soft type. 5. At present, most soft contact lens were a domestic production, and some subjects were foreign country production, but some subjects were unknown. 6. After contact lens wear, most subjects don't known the corrected visual acuity, especially, almost people don't known the binocular visual acuity. 7. At present, on soft contact lens color, the teens like the non-color contact lens, twenties like the color contact lens, but thirties was not known. 8. On the advantage of soft contact lens knowledge, most teens and twenties were only one, thirties was unknown. 9. On the disadvantage of soft contact lens knowledge, most teens and thirties were only one, twenties were two. 10. On the side effect of soft contact lens wearer, teens was one, and twenties and thirties don't known. 11. On the main symptoms of soft contact lens wearer, total kinds were seven, On these kinds, most subjects were not symptoms, the next order was unknown on the symptom. But, On the symptoms, the main symptoms was the pain and dry eye. 12. At present, the research on the surface morphology of soft contact lens by inverted microscope, the lens repture, lens folding, foreign body immersion and etc were present. Above the study, most contact lens was soft lens, and the purchase was the optical shop, on the other hand, the knowledge of soft contact lens and visual acuity was few. As a results, On the practical problems of soft contact lens wear, the optician have to the soft contact lens treatment and aftercare by law and educational supporting.

• Journal of Korean Ophthalmic Optics Society
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• v.19 no.1
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• pp.31-42
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• 2014

Purpose: The present study was conducted to investigate the effect of the physical properties of RGP lens induced by lens polishing on the actual wearer's subjective comfort, the tear film break-up time and the blinking rate as a follow-up study that revealed the relationship between the lens physical properties during lens manufacturing and lens wearer's factors. Methods: RGP lenses made from the three different polishing conditions (25, 50 and 100 seconds) were applied on 28 eyes of 17 subjects, aged 20 to 29 years, without any known disease and surgical history in the eyes. While the subjects were asked to wear the RGP lenses longer than a week, the questionnaire for the comfortability was administered everyday. Subjective and objective tear break-up time and blinking rate of the wearers were further measured. Results: The wearer's subjective comfortability showed some difference in the type of discomfort and satisfaction score according to the polishing status when wearing RGP lenses made from different polishing conditions longer than a week, and a bigger difference in satisfaction score induced by polishing condition was especially shown in experienced RGP lens wearer rather than un-experienced wearer. In the case of RGP lens wearer compared with the ones without the wearing experience, as the wearing time increased subjective and objective tear break-up time were increased and the blinking rate was decreased. However, subjective and objective tear break-up time were tended to decrease with even longer wearing time when wearing the RGP lens made from the polishment for 100 seconds. Conclusions: These results confirmed that the optimization of physical properties of the lens may not give the same effect on the wearer's subjective and objective symptoms and other factors when actual wearing. From the results, it can suggest that the success rate of RGP lens wear may be changed by physiological factors such as the stabilization of wearer's tear film, comfortability and lens wearing experience when wearing RGP lens based on 'The manufacturing standard for soft contact lens/hard contact lens' provided by Korea Food and Drug Administration.

• Journal of Korean Ophthalmic Optics Society
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• v.20 no.4
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• pp.445-454
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• 2015

Purpose: The present study was aimed to investigate the effect of tear volume on a change of axial rotation according to wearing time of toric soft contact lens and gaze directions. Method: Toric soft contact lenses with double thin zone design applied on 62 eyes. Then, changes in non invasive tear film break-up time and the rotational direction/amount of lens when changing gaze direction were respectively measured after 15 minutes and 6 hours of lens wear. Results: Lens rotation to temporal direction was more found when changing gaze direction after lens wear. However, its rotation was varied according to wearing time and the subjects' tear volume. Furthermore, the frequency of lens rotation to temporal direction was higher in dry eyes compared with normal eyes at nearly all gaze directions after 15 minutes and 6 hour of lens wear. The rotational amount of lens was generally greater in dry eyes after 15 minutes of lens wear. However, its difference between normal eyes and dry eyes was not great after 6 hours of lens wear. Conclusion: The present study revealed that axial rotation of toric soft contact lens was varied according to the wearer's tear volume and lens rotational patterns at the initial, and extending periods of lens wear were different. The change in rotational pattern of toric soft contact lens from these results means the possibility of visual change after extending lens wear, and the identification of its correlation with tear volume suggests the necessity of considering factors for choosing appropriate toric soft contact lens.

• Journal of Korean Ophthalmic Optics Society
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• v.7 no.2
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• pp.101-105
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• 2002

Spontaneous blinking as a function of visual activity and environmental condition with 60 healthy Korean young people(M=30, F=30) was estimated. Spontaneous blink rate of male and female was $19.2{\pm}2.0/min$ and $18.7{\pm}2.0/min$, respectively. There was no significant difference of blink rate in both contact lens wearer and non-wearer of female and also by various visual activity between female and male. Spontaneous blink rate was changed in response to changes in levels of visual activity and environmental condition such as windiness, rut not changed by light. In the more intense fixation spontaneous blink rate was lesser, but in the stronger windiness, the rate was higher than that in normal.

• Journal of Korean Ophthalmic Optics Society
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• v.12 no.4
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• pp.127-131
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• 2007

This study was designed to demonstrate the ability of Texas Eye Research and Technology Center Dry Eye Questionaire (TERTC-DEQ) to examine the distribution of self-reported dry eye symptoms and their diurnal intensity in university students and compare it with McMonnies & Ho DEQ. Two dry eye questionnaires were administered to 46 contact lens wearers and 47 nonwearers. Contact lens wearers scored higher on the TERTC-DEQ (52.2%) than McMonnies & Ho DEQ (6.5%). Non-contact lens wearers also scored higher on the TERTC-DEQ (19.1%) than McMonnies & Ho DEQ (2.1%). Ocular symptoms worsened with progression of time of day in both groups of subjects. This study suggests that TERTC-DEQ provides a first-choice diagnosis tool to obtain a comprehensive assessment of patient's symptoms, especially in comparison with McMonnies & Ho DEQ. The TERTC-DEQ is an efficient screening survey and may be use in dry eye diagnosis of contact lens-related dry eye.