• 한국콘텐츠학회논문지
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• 제22권6호
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• pp.354-368
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• 2022

본 연구의 목적은 방과 후 음악활동에 참여한 초등학생과 참여하지 않은 학생들의 정서지능, 학교적응, 자아 탄력성, 긍정적 대인관계, 우울의 수준과 관계에 있어 유의한 차이가 나타나는지 검증하는데 그 목적이 있다. 수도권 및 경남지역 초등학교 4, 5, 6학년 학생 중 방과 후 음악활동에 참여하는 학생 379명과 참여하지 않은 학생 368명 총 747명이 본 연구에 참여하였다. 연구분석을 위해 t-test와 다중집단분석을 실시하였으며 분석된 결과는 다음과 같다. 첫째, 방과 후 음악활동에 참여한 집단이 참여하지 않은 집단에 비해 정서지능, 자아탄력성, 긍정적 대인관계, 학교적응의 수준은 높고 우울 수준은 낮은 것으로 나타났다. 둘째, 다중집단분석을 실시한 결과 참여 집단이 비참여 집단에 비해 [정서지능→자아탄력성], [정서지능→긍정적 대인관계], [정서지능→우울], [정서지능→학교적응], [자아탄력성→학교적응]의 경로에 있어 더 강하게 영향을 미치고 있는 것으로 나타났다. 셋째, 매개효과를 분석한 결과 방과 후 음악활동에 참여한 집단에서는 정서지능과 학교적응 간의 관계에서 자아탄력성, 긍정적 대인관계, 우울이 모두 매개효과가 있는 것으로 나타난 반면, 방과 후 음악활동에 참여하지 않은 집단에서는 정서지능과 학교적응 간의 관계에서 자아탄력성과 우울 변인만이 유의한 매개효과가 있는 것으로 나타났다.

• International Journal of Quality Innovation
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• 제8권3호
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• pp.1-10
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• 2007

A sample of Italian manufacturing companies was selected in order to verify the abilities and effects (relationships) of the management factors human resources, leadership and strategic planning on company performance. The Partial Least Squares (PLS) estimation method was used for analyzing the data collected, where the relationships between the management factors and performance were formalized by a Structural Equation Model (SEM). The analysis of the survey data showed unexpected result regarding the non significant direct relationship between Leadership and Performance. The effect of Leadership is obtained by an indirect relationship through Human Resources. The combination of Leadership and Human Resources has hence been identified as the management factors which have the highest impact on the performance of Italian industrial companies. Another interesting and unexpected result was that there was no significant impact of Strategic Planning on Performance. It seems that the leaders of Italian industrial companies have not understood that good strategic planning is a necessary condition for achieving excellence. So another improvement area is in fact Strategic Planning. This area should have the highest priority of any top management team and the focus should include how to establish a strong relationship between strategic planning and performance. No correlation between strategic planning and performance is a strong indication that something is wrong. It is not enough that Leadership is doing Strategic Planning-Leadership is also about studying and follow up on results in order to assure impacts on performance. This link seems to be missing in Italian industrial companies.

• Nuclear Engineering and Technology
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• 제41권5호
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• pp.747-752
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• 2009

A vulnerability assessment is essential for the efficient operation of a physical protection system (PPS). Previous assessment codes have used a simple model called an adversary sequence diagram. In this study, the use of a two-dimensional (2D) map of a facility as a model for a PPS is suggested as an alternative approach. The analysis of a 2D model, however, consumes a lot of time. Accordingly, a generalized heuristic algorithm has been applied to address this issue. The proposed assessment method was implemented to a computer code; Systematic Analysis of physical Protection Effectiveness (SAPE). This code was applied to a variety of facilities and evaluated for feasibility by applying it to various facilities. To help upgrade a PPS, a sensitivity analysis of all protection elements along a chosen path is proposed. SAPE will help to accurately and intuitively assess a PPS.

• Asian Pacific Journal of Cancer Prevention
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• 제16권16호
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• pp.7255-7260
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• 2015

Background: Recent reports have shown that DLC-1 is widely expressed in normal tissues and is down-regulated in a wide range of human tumors, suggesting it may act as a tumor suppressor gene. We conducted a meta-analysis to determine the correlation between DLC-1 expression and clinicopathological characteristics in cancers. Materials and Methods: A detailed literature search was made for relevant publications from PubMed, EMBASE, Cochrane library databases, Web of Science, CNKI. The methodological quality of the studies was also evaluated. Analyses of pooled data were performed and odds ratios (ORs) were calculated and summarized. Results: Final analysis was performed of 1,815 cancer patients from 19 eligible studies. We observed that DLC- 1 expression was significantly lower in cancers than in normal tissues. DLC-1 expression was not found to be associated with tumor differentiation status. However, DLC-1 expression was obviously lower in advance stage than in early-stage cancers and was more down-regulated in metastatic than non-metastatic cancers. Conclusions: The results of our meta-analysis suggested that DLC-1 expression is significantly lower in cancers than in normal tissues. Aberrant DLC-1 expression may play an important role in cancer genesis and metastasis.

• IMMUNE NETWORK
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• 제9권1호
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• pp.4-7
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• 2009

Although the success of trastuzumab and rituximab for treatment of breast cancer and non-Hodgkins lymphoma, respectively, suggests that monoclonal antibodies(mAbs) will become important therapeutic agents against a wider range of cancers, useful therapeutic Abs are not yet available for the majority of the human cancers because of our lack of knowledge of which antigens (Ags) are likely to become useful targets. We established a procedure for comprehensive identification of such Ags through the extensive isolation of human mAbs that may be therapeutic. Using the phage-display Ab library we isolated a large number of human mAbs that bind to the surface of tumor cells. They were individually screened by immunostaining, and clones that preferentially and strongly stained the malignant cells were chosen. The Ags recognized by those clones were isolated by immunoprecipitation and identified by mass spectrometry(MS). We isolated 2,114 mAbs with unique sequences and identified 25 distinct Ags highly expressed on several carcinomas. Of those 2,114 mAbs 434 bound to specifically to one of the 25 Ags. I am going to discuss how we could select proper target Ags for therapeutic Abs and candidate clones are therapeutic agents.

• 환경영향평가
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• 제19권3호
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• pp.259-270
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• 2010

We conducted human risk assessment for exposure to inhalation of chemical substances emitted from the storage tanks of petroleum refineries. To assess human risk, this study calculated chemical emissions from the external floating roofs on storage tank at petroleum refineries, as well as concentrations thereof in the ambient air using the K-SCREEN model, and then determined risk in accordance with the Reference Concentration (RfC) values and Inhalation Unit Risk criteria developed by the US Environmental Protection Agency. The results indicated that non-carcinogenic chemicals have a hazard quotient of less than 1, meaning they have an insignificant effect on human health for residential areas near the storage tanks. Among the known carcinogens, the hazard risk for benzene slightly exceeded $10^{-6}$, indicating the need for corrective reduction measures. The methodology for health impact assessment devised herein provides findings useful in decision making for policy makers and the general public with respect to construction of industrial complexes. However, the methodology proposed herein does have limitations, including discrepancy in results induced by use of U.S. data (due to the lack of usable domestic data). More systematic studies from related researchers will be needed to address these issues and produce more reliable outcomes.

• 한국생활과학회지
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• 제16권1호
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• pp.111-121
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• 2007

The purpose of this study was to examine university students' clothing and cosmetics purchasing behaviors according to gender and major. For the study, 337 university students living in Chonbuk area participated in this survey research. The data were analyzed utilizing SPSS statistics package. Exploratory factor analysis, reliability test, and t-test were used. Five factors in each clothing and cosmetics purchasing orientation were generated from the factor analysis. According to gender and major, clothing and cosmetics purchasing behavior were significantly different. Female students showed more impulsive, rational, and economical purchasing orientations than male students did. On the contrary, male students showed more independent and convenient purchasing orientations. The students with fashion design major showed higher tendency in impulsive and rational clothing purchasing orientations than non-fashion design major students. Finally, clothing and cosmetics purchasing behaviors were significantly different by gender and major in terms of information usage and expenditure for clothing and cosmetics.

• 한국콘텐츠학회논문지
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• 제4권4호
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• pp.171-178
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• 2004

라디오 주파수 마이크로파는 시료에서 포도당 농도를 측정하기 위해 사용될 수 있다. 본 논문에서는 포도당을 포함하는 증류수, 샐라인, 인체 씨럼, 인체 혈액 용액에 대해서 상대 유전율을 측정함으로써 포도당 농도 측정의 예비 실험 결과를 보고한다. 근육과 같은 인체 조직의 포도당 농도 측정에서 마이크로파 방법은 NIR방법보다 투과 깊이가 약 100배 더 컸으며, 이것은 인체의 포도당을 비침습적인 검출에 더 유용한 장점이 된다. 실험에서 인체 혈액 용액에서 포도당 농도를 검출하기 위한 측정 감도는 5.8GHz부근에서 약 57mg/dl를 보였다.

• 약학회지
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• 제44권6호
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• pp.595-600
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• 2000

Transdermal delivery of ketorolac tromethamine, a potent non-narcotic analgesic, through human cadaver skin was investigated in vitro. A mixture of ethanol/water (40/60) containing 0, 1, 3, 5, and 8 (w/v)% L-menthol were used as a vehicle and penetration enhancer respectively. The permeation of ketorolac through human cadaver skin from saturated drug solution was evaluated at $37^{\circ}C$ with modified Franz diffusion cell. The in vitro skin flux and lag time were $1.23\;{\pm}\;0.11\;{\mu}g/cm^2{\cdot}hr$ and $5.56\;{\pm}\;0.34\;hr$, respectively. The cumulative amount of penetrated ketorolac containing L-menthol in ethanol/water (40/60) binary system was increased by the following order; 3%, 5%, 8%, 1%, 0%, and the lag time was decresed by the following order; 3%, 5%, 8%, 0%, 1%. The results suggested that a potential use of 3% L-methol is an effective penetration enhancer of ketorolac tromethamine through the human cadaver skin.

• Asian Pacific Journal of Cancer Prevention
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• 제16권18호
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• pp.8187-8190
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• 2016

Human papillomaviruses (HPVs) are small, non-enveloped, double-stranded DNA viruses that infect epithelial tissues. Specific genotypes of human papillomavirus are the single most common etiological agents of cervical intraepithelial lesions and cervical cancer. Cervical cancer usually arises at squamous metaplastic epithelium of transformation zone (TZ) of the cervix featuring infection with one or more oncogenic or high-risk HPV (HR-HPV) types. A hospital-based study in a rural set up was carried out to understand the association of HR-HPV with squamous intraepithelial lesions (SILs) and cervical cancer. In the present study, HR-HPV was detected in 65.7% of low-grade squamous intraepithelial lesions (LSILs), 84.6% of high-grade squamous intraepithelial lesions (HSILs) and 94% of cervical cancer as compared to 10.7% of controls. The association of HPV infection with SIL and cervical cancer was analyzed with Chi square test (p<0.001). The significant association found confirmed that detection of HR-HPV is a suitable candidate for early identification of cervical precancerous lesions and in the prevention of cervical cancer in India.