• Journal of Microbiology and Biotechnology
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• 제25권3호
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• pp.343-352
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• 2015

H9 is an ethanol extract prepared from nine traditional/medicinal herbs. This study was focused on the anticancer effect of H9 in non-small-cell lung cancer cells. The effects of H9 on cell viability, apoptosis, mitochondrial membrane potential (MMP; ${\Delta}\psi_{m}$), and apoptosisrelated protein expression were investigated in A549 human lung cancer cells. In this study, H9-induced apoptosis was confirmed by propidium iodide staining, expression levels of mRNA were determined by reverse transcriptase polymerase chain reaction, protein expression levels were checked by western blot analysis, and MMP (${\Delta}\psi_{m}$) was measured by JC-1 staining. Our results indicated that H9 decreased the viability of A549 cells and induced cell morphological changes in a dose-dependent manner. H9 also altered expression levels of molecules involved in the intrinsic signaling pathway. H9 inhibited Bcl-xL expression, whereas Bax expression was enhanced and cytochrome C was released. Furthermore, H9 treatment led to the activation of caspase-3/caspase-9 and proteolytic cleavage of poly(ADP-ribose) polymerase; the MMP was collapsed by H9. However, the expression levels of extrinsic pathway molecules such as Fas/FasL, TRAIL/TRAIL-R, DR5, and Fas-associated death receptor were downregulated by H9. These results indicated that H9 inhibited proliferation and induced apoptosis by activating intrinsic pathways but not extrinsic pathways in human lung cancer cells. Our results suggest that H9 can be used as an alternative remedy for human non-small-cell lung cancer.

• Nutrition Research and Practice
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• 제10권3호
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• pp.359-363
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• 2016

BACKGROUND/OBJECTIVES: This study aimed to examine the association of Japanese schoolchildren's involvement in at-home meal preparation with food intake and cooking skill. SUBJECTS/METHODS: We included 1,207 fifth-grade children aged 10-11 years and one parent of each child. A cross-sectional survey was used to collect data on involvement in at-home meal preparation. Correspondence analysis was used to classify involvement in at-home meal preparation into three groups: food-related activities (cooking only or with other activities such as shopping, table-setting, clean up, and dishwashing), non-food-related activities (table-setting and/or clean up), and no (helping) activities. Food intake was assessed using a food frequency questionnaire. Logistic regression models were used to examine involvement in at-home meal preparation associations. RESULTS: The sample consisted of 1,207 fifth-grade children. Vegetable intake was lower in the no (helping) activities group than the food-related activities group (95% CI; boys: 1.2, 5.1, girls: 2.0, 8.9). Fewer children in the non-food-related activities group reported they were able to make a portion of their meals compared with the food-related activities group (95% CI; boys: 1.6, 3.5; girls: 1.5, 3.2). CONCLUSIONS: Children in the food-related activities group showed more favorable food intake and cooking skills than children in the no (helping) activities or non-food-related activities group.

• 한국융합학회논문지
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• 제8권9호
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• pp.9-16
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• 2017

본 연구는 비 침습 방식으로 인체 혈당변화를 감지하여 준 마이크로파 대역의 발진 주파수 변화로 나타내는 발진기 센서를 제안하였다. 마이크로스트립 선로의 접지 면에 형성된 유도성 슬롯(inductive slot)과 생체조직 사이에 전자기적 결합을 통해 공진기로 구현되었으며, 능동회로를 연결하여 발진기를 구현하였다. 생체 조직을 가상한 팬텀 박스를 이용하였고, 3단계(0, 400, 800 mg/dL)의 혈당 농도 수준을 변화시켰을 때 공진기의 공진주파수가 상향 이동하는 것을 시뮬레이션 하였다. 시제품을 제작하여 인체 대신 돼지의 생체를 이용하여 실험한 결과, 1,100 MHz 부근에서 400 mg/dL의 혈당 농도변화 대비 약 14 MHz의 발진 주파수 천이가 관찰되어 혈당 센서에 적용할 수 있음을 확인하였다.

• 한국수산과학회지
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• 제54권1호
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• pp.16-22
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• 2021

This study investigated the reduction in human norovirus (HNV) GII. 4 count in pacific oyster Crassostrea gigas using electron beam irradiation. Infectious HNV GII. 4 was detected using RT-qPCR (real time reverse transcription-quantitative polymerase chain reaction) with PMA (propidium monoazide)/sarkosyl. At electron beam doses 1, 5, 7, and 10 kGy, the count of HNV GII. 4 was 2.74, 2.37, 2.06, and 1.55 log copies/μL (control, 3.01 log copy/μL), respectively, confirming that as the irradiation dose increased, norovirus count reduced significantly (P<0.05). After PMA/sarkosyl treatment, the counts further reduced at the same irradiation dose, and 10 kGy showed significant differences between the non-treated and PMA/sarkosyl-treated samples (P<0.05). The Ed (decimal reduction dose of electron beam) value based on the first-order kinetic model was 7.33 kGy (R2=0.98). No significant difference was observed in the pH values of the control (6.2) and electron beam-irradiated samples at all doses (6.1). For sensory evaluation, the non-treated sample scored the highest in all categories (5.25-6.17), while the samples treated with 10 kGy showed the lowest score (4.67-5.33), although without statistical significance (P>0.05). Overall, our results suggest that 7 kGy electron beam is sufficient for the non-thermal sterilization of oysters without causing significant changes in quality.

• 한국한의학연구원논문집
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• 제1권1호
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• pp.273-287
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• 1995

Moire topography, a simple technique for three-dimensional quantitation, was used to provide interference fringe photographs of the human back with sufficient accuracy to be used for detecting patient with asymmetry due to scoliosis, the disease of cervix and lumbar, muscle dysfunction. Contour lines are a suitable and widely accepted method of describing a three-dimensional surface. In the moire technique, contour lines of an object are produced as interference fringes while the object is illuminated by a spotlight through a special grating. The fringe pattern is produced by the interference of the grating and its shadow on the object. A photograph of a moire pattern on the human back will permit an assessment of the overall body shape and the symmetry of the back. This study uses shadow moire topography. Moire topography provides a non-invasive technique for quantifying the shape of the human body. In the use of moire topography for the Oriental Medicine Diagnosis, the strength of moire lies in the ablility to detect change due to deformity of human body.

• 한국멀티미디어학회논문지
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• 제15권4호
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• pp.501-507
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• 2012

Human body motion is a non-verbal part for interaction or movement that can be used to involves real world and virtual world. In this paper, we explain a study on natural user interface (NUI) in human hand motion recognition using RGB color information and depth information by Kinect camera from Microsoft Corporation. To achieve the goal, hand tracking and gesture recognition have no major dependencies of the work environment, lighting or users' skin color, libraries of particular use for natural interaction and Kinect device, which serves to provide RGB images of the environment and the depth map of the scene were used. An improved Camshift tracking algorithm is used to tracking hand motion, the experimental results show out it has better performance than Camshift algorithm, and it has higher stability and accuracy as well.

• Journal of Nutrition and Health
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• 제27권8호
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• pp.864-871
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• 1994

The productivity and 13 influencing variables in 14 conventional hospital foodservice systems the total direct and non-direct labor hours required to produce and serve the total number of patient meals plus the number of cafeteria meals. Human resource variable significantly influencing the productivity level was the labor cost. As this index decreased, the meals served per human hour worked increased. System resource variables correlating significantly with productivity were the length of cycle menu, the ratio of staff meals, and modified patient meal ratio. As the length of cycle menu and the ratio of modified patient meal decreased, more meals were produced per human hour. However, as staff meal ratio increased, the meals served per human hour worked increased. The stepwise regression analysis suggests that around 53% of the variance in productivity is explained by labor cost.

• 로봇학회논문지
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• 제4권4호
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• pp.281-288
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• 2009

Nowadays, many robots have evolved to imitate human social skills such that sociable interaction with humans is possible. Socially interactive robots require abilities different from that of conventional robots. For instance, human-robot interactions are accompanied by emotion similar to human-human interactions. Robot emotional expression is thus very important for humans. This is particularly true for facial expressions, which play an important role in communication amongst other non-verbal forms. In this paper, we introduce a method of creating lifelike facial expressions in robots using variation of affect values which consist of the robot's emotions based on emotional boundaries. The proposed method was examined by experiments of two facial robot simulators.

• 한국멀티미디어학회논문지
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• 제7권12호
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• pp.1692-1699
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• 2004

Many researchers have developed various techniques for detection of human faces in ordinary still images. Face detection is the first imperative step of human face recognition systems. The two main problems of human face detection are how to cutoff the running time and how to reduce the number of false positives. In this paper, we present frontal and near-frontal face detection algorithm in still gray images using a thick edge image and neural network. We have devised a new filter that gets the thick edge image. Our overall scheme for face detection consists of two main phases. In the first phase we describe how to create the thick edge image using the filter and search for face candidates using a whole face detector. It is very helpful in removing plenty of windows with non-faces. The second phase verifies for detecting human faces using component-based eye detectors and the whole face detector. The experimental results show that our algorithm can reduce the running time and the number of false positives.

• 대한안전경영과학회지
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• 제12권1호
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• pp.137-148
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• 2010

Aimed at fostering global human resource and utilizing it, this study presents a more systematic approach for encouraging overseas employment of the young generation. This study suggests a method for the objective evaluation of the overseas employment program through to used the M. Porter's 5-Forces and business administrative technologies. The result of this research will allow us to suggest a well-organized and more systematic frame of the international exchange programs, in which various new policies can be found. Since the overseas employment program is a non-standard, yet important, national policy plan, the future direction of the program was suggested based on the data of the previously-promoted programs.