• 제목/요약/키워드: new stimulation

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Starting Current Application for Magnetic Stimulation

  • Choi, Sun-Seob;Bo, Gak-Hwang;Kim, Whi-Young
    • Journal of Magnetics
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    • 제16권1호
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    • pp.51-57
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    • 2011
  • A power supply for magnetic-stimulation devices was designed via a control algorithm that involved a start current application based on a resonant converter. In this study, a new power supply for magnetic-stimulation devices was designed by controlling the pulse repetition frequency and pulse width. The power density could be controlled using the start-current-compensation and ZCS (zero-current switching) resonant converter. The results revealed a high-repetition-frequency, high-power magnetic-stimulation device. It was found that the stimulation coil current pulse width and that pulse repetition frequency could be controlled within the range of 200-450 ${\mu}S$ and 200-900 pps, respectively. The magnetic-stimulation device in this study consisted of a stimulation coil device and a power supply system. The maximum power of the stimulation coil from one discharge was 130 W, which was increased to 260 W using an additional reciprocating discharge. The output voltage was kept stable in a sinusoidal waveform regardless of the load fluctuations by forming voltage and current control using a deadbeat controller without increasing the current rating at the starting time. This paper describes this magnetic-stimulation device to which the start current was applied.

전기자극 조건에 따른 근육 세포에 미치는 영향과 반응 (Effect and Response of Skeletal Muscle Cells on Electrical Stimulation Condition)

  • 서형우;신현영;이현주;태기식;김민석
    • 대한의용생체공학회:의공학회지
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    • 제38권6호
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    • pp.308-312
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    • 2017
  • Skeletal muscle function plays a very important role in quality of life. However, skeletal muscle causes functional decline under aging or some diseases. Exercise and muscle training are good solutions to delay sarcopenia, but there are limitations to those who are uncomfortable in exercise. For this reason, alternative interventions for muscle sarcopenia are required, and many studies proved the increase of skeletal muscle mass by electrical stimulation. In conventional studies, however, mouse skeletal muscle cells have been mostly used in experiments to identify electrical stimulation conditions while human derived cells have not been frequently utilized in these studies. Stimulation used for rehabilitation has been uniformly treated without the consideration of aging. In addition, many studies have been used with conventional petri dish usually requiring many numbers of cells, which is not appropriate for rare. Moreover, they are not usually condition uniformity of electrical field. In this study, we have developed an electrical stimulation device which consumes a small amount of cells and can form a uniform electrical field. With the system, we analyzed the skeletal muscle differentiation and Myotube thickness depending on the electrical stimulation condition.

Transcranial direct current stimulation for spinal cord injury-associated neuropathic pain

  • Li, Caixia;Jirachaipitak, Sukunya;Wrigley, Paul;Xu, Hua;Euasobhon, Pramote
    • The Korean Journal of Pain
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    • 제34권2호
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    • pp.156-164
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    • 2021
  • Several types of pain occur following spinal cord injury (SCI); however, neuropathic pain (NP) is one of the most intractable. Invasive and non-invasive brain stimulation techniques have been studied in clinical trials to treat chronic NP following SCI. The evidence for invasive stimulation including motor cortex and deep brain stimulation via the use of implanted electrodes to reduce SCI-related NP remains limited, due to the small scale of existing studies. The lower risk of complications associated with non-invasive stimulation, including transcranial direct current stimulation (tDCS) and repetitive transcranial magnetic stimulation (rTMS), provide potentially attractive alternative central neuromodulation techniques. Compared to rTMS, tDCS is technically easier to apply, more affordable, available, and potentially feasible for home use. Accordingly, several new studies have investigated the efficacy of tDCS to treat NP after SCI. In this review, articles relating to the mechanisms, clinical efficacy and safety of tDCS on SCI-related NP were searched from inception to December 2019. Six clinical trials, including five randomized placebo-controlled trials and one prospective controlled trial, were included for evidence specific to the efficacy of tDCS for treating SCI-related NP. The mechanisms of action of tDCS are complex and not fully understood. Several factors including stimulation parameters and individual patient characteristics may affect the efficacy of tDCS intervention. Current evidence to support the efficacy of utilizing tDCS for relieving chronic NP after SCI remains limited. Further strong evidence is needed to confirm the efficacy of tDCS intervention for treating SCI-related NP.

전기자극이 치조골 치유과정에 미치는 영향 (EFFECT OF ELECTRICAL STIMULATION ON BONE FORMATION IN THE EXTRACTION SOCKET OF RAT)

  • 양승한;이만섭;박준봉;허익
    • Journal of Periodontal and Implant Science
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    • 제31권4호
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    • pp.669-687
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    • 2001
  • On the basis of the evidence that electrical stimulation could promote healing and regeneration of bone, this study was performed to investigate the effects of electrical stimulation on rat extraction socket, and to evaluate the potential of clinical application of electrical stimulation. Forty rats were used and divided into control groups(l0)and the experimental groups(30) in this study. The maxillary 1st molar were extracted in both groups. In experimental group, electrical stimulation was given at the current intensity of lmA(Test-1), l0mA(Test-2), 25mA(Test-3) each day. At 1,3,5,7 days after the tooth extraction, rats in both groups were serially sacrificed. And the specimens were prepared with Hematoxylin-Eosin stain for the light microscopic evaluation. The results of this study were as follows; 1. At 1 day after the extraction, the periodontal ligament was found in the extraction socket wall. The formation of blood clot with dense infiltration of inflammatory cells in control group and there were less inflammatory cells in test group. 2. At 3 day after the extraction, the cells and collagen of the periodontal ligament were so actively proliferated and synthesized that invaded into the connective tissue of the extraction sockets in the control group. There were the formation of new bone in the basal & lateral portion of socket wall in test -2 and -3. 3. At 5 days after the extraction, there were no formation of new bone in control group. But the more electrical stimulation was applied, the more formation of new bone in test group. 4. At 7 days after the extraction, the extraction sockets were almost filled with trabecular bone in each group. Bone maturarity was remarkable in test-3. 5. The electrical stimulation at l0mA and 25mA was more effective in the bone formation at 5 and 7 days after the extraction. From the above results, electrical stimulation could promote the extraction socket wound healing, and be utilized in the clinical application of the residual ridge expansion.

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윈도우 환경하에서 근전도의 실시간 Silent Period 측정 시스템 설계 (A Design of Real Time Measurement System for EMG Silent Period Under Window Base)

  • 강병길;김태훈;이영석;김덕영;김세동;김성환
    • 대한전기학회논문지:시스템및제어부문D
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    • 제52권10호
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    • pp.611-617
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    • 2003
  • A mechanical or electrical stimulation to the mandibular symphysis during a maximal voluntary clenching of the teeth always produces a jaw jerk followed by a silent period (transient stops) in the masseteric EMG (electromyogram). Generally, a mechanical stimulation is followed by a single silent period, and an electrical stimulation is followed by multiple silent periods. In this paper, we propose a new algorithm for determining the duration of the masseter silent period. The decision approach in essentially based upon a segmentation algorithm consisted of variance filter, median filter and gaussian filter. The new adaptive digital notch filter using R-CLMS(reverse constrained least mean-squared) algorithm is proposed for the elimination of powerline(60Hz) noise. At the same time, we design a real time measurement system for the EMG silent period under Window base.

체외 전기자극기가 심장에 미치는 영향의 분석 및 평가 (Analysis of an External Stimulator's Impact on the Heart)

  • 김문수;최성욱
    • 대한기계학회논문집B
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    • 제35권11호
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    • pp.1213-1217
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    • 2011
  • 의료용 자극기는 병원과 가정에서 환자의 통증 경감 및 재활 치료를 위해 사용되는 의료기기이다. 전기자극기의 자극 펄스가 심장에 유입되면 부정맥 및 심실세동 등의 심각한 부작용을 초래할 수 있다. 의료용 자극기에서 공급하는 자극 펄스의 전달 거리를 측정하고 심장이 전기 자극의 위험 범위 밖에 위치하도록 자극의 크기 및 자극 부위를 제한할 필요가 있다. 전기 자극기는 초당 60 회의 빈도로 0.001Joule 전기 펄스를 가하도록 설계되었다. 전기 자극기의 성능 및 인체에 미치는 영향을 측정하기 위해 생리 식염수를 이용한 생체 조직의 모델을 제작하였고, 이를 이용하여 거리에 따른 전기장의 감쇄 정도를 측정하였다. 본 연구에서 개발한 전기 자극기를 동물실험에 적용한 후 심장 주변에 전기자극을 가했을 때 심장에서 나타나는 위험요인을 관찰하고 직류전류가 흘렀을 때 심장에서 나타나는 현상과 비교하였다.

Distinguishing Online Opinion Leaders: The Mediating Effect of Consumer Innovativeness and Online Opinion Leadership for Values and New Product Adoption Behavior

  • Lee, Yukyung;Park, Minjung;Im, Subin
    • Asia Marketing Journal
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    • 제19권2호
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    • pp.1-24
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    • 2017
  • This article empirically examines the relationship between values, consumer innovativeness, online opinion leadership, and new product adoption behavior utilizing wearable technology as the overall unit of analysis. The authors analyze data collected from SNS users who possess one or more wearable devices using a structural equation modeling approach to examine the direct effects. Moreover, a bootstrapping approach is adopted to explore the indirect effects between the constructs. The results indicate that consumers who value stimulation and hedonism are more inclined to possess stronger consumer innovativeness. Consumer innovativeness also positively influences online opinion leadership, ultimately leading to the faster adoption of new products. The mediating effect of consumer innovativeness between the value stimulation and online opinion leadership is also confirmed. In addition, although consumer innovativeness has no direct effect on new product adoption behavior, it does have an indirect, mediating effect through online opinion leadership.

fMRI를 이용하여 수지굴신운동(手指屈伸運動)과 조해(照海)(KI6) 자침(刺鍼)에 의(依)한 대뇌운동피질(大腦運動皮質)의 활성변화(活性變化)에 관(關)한 비교(比較) 연구(硏究) (The New Finding on BOLD Response of Motor Acupoint KI6(照海) by fMRI)

  • 권철현;이준범;황민섭;윤종화
    • Journal of Acupuncture Research
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    • 제21권6호
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    • pp.177-186
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    • 2004
  • Introduction : Recent studies Suggested that there is a strong correlation between acupuncture stimulation and its related cortical activation. Anther study showed that either positive or negative BOLD effects could be observed depending on anatomical structure in acupuncture stimulation. In ttis study, we investigated a new acupoint $KI_6$ (照海), which was known as motor-related acupoint and obtained an evidence that the stimulation of $KI_6$ resulted in either negative or positive BOLD response to stimulation. Methods & Results : 1. Subjects and paradigms : Two separate stimulation paradigms were performed on five healthy (aged 22-23 yrs) in this study. First, the paradigm of acupuncture stimulation was that the acupuncture needle was inserted in acupoints $KI_6$, which is located in lateral side of the foot and then continuously twisted(補瀉를 除外한 捻轉法) for 70 seconds for 10 cycles of activation. During rest period (70 seconds), the needle was completed removed from acupoint. Total 60 cycles were performed and 10 images were obtained per cycle. Second, nonacupoint was randomly selected and the same paradigm was performed as acupoint stimulation. The stimulation protocol comprised 10 cycles of alternating. activation and rest (10 images per cycle). Total 60 cycles were performed and each cycle take about 1.5 sec for motor task. Subjects take an at least 15 minutes break before starting anther paradigm. 2. fMRI mapping : Multi-slice functional images were obtained on a 1.5T Magnetom Vision MRI scanner (Simens Medical, Erlangen, Germany) equipped with high performance whole-body gradients. The BOLD T2 * - weighted images were acquired with acho planar imaging sequence (TR = 1.2 sec, TE = 60 msec, and flip angle = $90_{\circ}$). The other sequence parameter are : FOV = 210 mm, matrix=$64{\times}128$ or $64{\times}64$, slice number=10 and slice thickness = 5 or 8 mm. the anatomic images were obtained with Spin-echo T1-weighted images. The resulting images were then anaiyzed with STIMULATE (CMRR, U. of Minnesota) to generate functional maps using a student T-test (p < 0.005) and cluster analysis. Both positive and negative response were evaluated. Conclusions : We have observed the activation of the motor cortex by stimulating motor-related acupoint ($KI_6$). Among five subjects, negative BOLD response was shown in four and positive response in one. All subjects showed positive response to conventional finger flexion-extension task. To understand the detailed mechanisms of correlation between acupuncture stimulation and BOLD fMRI changes and two typs of response, further study strongly required.

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The Output Characteristics of Transcranial Magnetic Stimulation with Voltage Variable Capacitor-Charging System

  • Kim, Whi-Young
    • Journal of information and communication convergence engineering
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    • 제8권2호
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    • pp.205-211
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    • 2010
  • In this study, a Magnetic stimulation Pulse Train control technique is introduced and applied to Flyback converter operating in discontinuous conduction mode. In contrast to the conventional pulse width modulation control scheme, the principal idea of a Magnetic stimulation Pulse Train is to achieve output voltage regulation using high and low power pulses. The proposed technique is applicable to any converter operating in discontinuous conduction. However, this work mainly focuses on Flyback topology. In this paper, the main mathematical concept of the new control algorithm is introduced and simulations as well as experimental results are presented.

일정 전기자극하의 근력 상승 - 전기 자극 파형의 펄스 진폭과 펄스폭에 대한 의존성 (Muscle force potentiation during constant electrical stimulation - Dependence on pulse-amplitude and pulse-duration of electrical stimulation)

  • 김지원;강민영;공세진;엄광문
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2006년도 제37회 하계학술대회 논문집 D
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    • pp.2155-2156
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    • 2006
  • The purpose of this work is to investigate the fundamental properties of the gradual muscle force potentiation for the prediction of muscle force and body movement from the stimulation input with musculo-skeletal model. We investigated the dependence of force potentiation on both the pulse-amplitude and the pulse-duration. The experimental result showed that the force increment ratio during electrical stimulation decreased with pulse-amplitude. The force increment ratio decreased with short pulse-duration and was maintained to be constant with pulse-duration longer than $500{\mu}s$. A new model of the muscle potentiation based on these results is desired in the future.

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