• Title/Summary/Keyword: new stimulation

Search Result 377, Processing Time 0.03 seconds

Precision Speed Control of PMSM for Stimulation of the Vestibular System Using Rotatory Chair (전정기관 자극용 회전자극기를 위한 PMSM의 정밀 속도제어)

  • 이태호
    • Proceedings of the KIPE Conference
    • /
    • 2000.07a
    • /
    • pp.628-631
    • /
    • 2000
  • A new control method for precision robust speed control of a PMSM(Permanent Magnet Synchronous Motor) using load torque observer is presented. With this system we can obtain more reliable eye moving singal(nystagmus) Until now rotating chair system which is called 2D-optokinetic stimulator is used to make dizzincess. However an inclined rotating chair system witch is 3D-optokinetic stimulator is needed to obtain the precise dizziness data. This 3D-optokinetic sitimulator include unbalanced load aused by unbalanced center of mass. For this case new compensation method is considered to obtain robust speed control using load torque observer. To reduce the effect of this disturbance we can use dead-beat observer which has high gain. The application of the load torque observer is published in [1] for position control. A problem of using speed information such as amplifying effect of noise is reduce by moving average process. The experimental results are depicted in this paper to show the effect of this proposed algorithm.

  • PDF

Impacts of Innovative EU Companies on Smaller Emerging Markets under an Open Economy

  • Seo, Dae-Sung
    • Journal of Distribution Science
    • /
    • v.12 no.10
    • /
    • pp.37-45
    • /
    • 2014
  • Purpose - This study aims to analyze the relationship between trends in innovative EU industries and market distribution in smaller emerging markets under an open economy. Research design, data, and methodology - Although innovation was well-distributed, due to socio-economic factors following European integration, CEE had not achieved sustainable economic growth. However, this paper analyzes the differences among changes in CEE innovation for smaller emerging markets dominated since 2000. Market distribution has facilitated new markets for innovative industries, according to EU surveys and economic indicators. Results - The dominance of the local industrial market distribution has deterred innovation investment the survey shows that innovation investment has been shrinking, despite the EU's open innovation policy for CEE employment and R&D. For the CEE case, there were expectation gaps and uncertainty about whether to use the new distribution dominance or TNCs' innovation in smaller emerging countries without local industrial innovation. Conclusions - Innovation generates market growth and distribution power however, small growth requires stimulation, and creativity and innovative edge need further focus in local public and corporate strategy.

Involvement of lncRNA-HOTTIP in the Repair of Ultraviolet Light-Induced DNA Damage in Spermatogenic Cells

  • Liang, Meng;Hu, Ke
    • Molecules and Cells
    • /
    • v.42 no.11
    • /
    • pp.794-803
    • /
    • 2019
  • Ultraviolet light (UV)-induced cellular response has been studied by numerous investigators for many years. Long noncoding RNAs (lncRNAs) are emerging as new regulators of diverse cellular process; however, little is known about the role of lncRNAs in the cellular response to UV treatment. Here, we demonstrate that levels of lncRNA-HOTTIP significantly increases after UV stimulation and regulates the UV-mediated cellular response to UV through the coordinate activation of its neighboring gene Hoxa13 in GC-1 cells (spermatogonia germ cell line). UV-induced, G2/M-phase arrest and early apoptosis can be regulated by lncRNA-HOTTIP and Hoxa13. Furthermore, lncRNA-HOTTIP can up-regulate ${\gamma}-H_2AX$ and p53 expression via Hoxa13 in UV-irradiated GC-1 cells. In addition, p53 has the ability to regulate the expression of both lncRNA-HOTTIP and Hoxa13 in vitro and in vivo. Our results provide new data regarding the role lncRNAs play in the UV response in spermatogenic cells.

"Milling Recovery of Rice at Local Milling Plants" (임도정공정 미곡 도정실태)

  • 김용환;서상용;김성태;나우정;민영봉
    • Journal of Biosystems Engineering
    • /
    • v.4 no.2
    • /
    • pp.1-8
    • /
    • 1979
  • This study was carried out to investigated the actual state of rice milling at local milling plants and to find out sources for elevating their milling recoveries in both quantity and quality. At 36 local milling plants located in Gyeongnam and Jeonnam , milling recoveries and head rice recoveries were measured with respect to their different milling systems and rice varieties. Then, the same samples of rice were milled by experimental milling equipments at laboratory, and the two experimental results were compared in order to determine the amount of milling recovery possibly to be increased. The results of this study are as follows ; 1. Milling recoveries of rice at local milling plants were proved to have no relationship with milling systems, and were 68.1% per ent and 72.6percent on an average with new variety and native variety, respectively. 2. The milling recoveries above stated can be elevated 4.5 percent and 2.9percent with new variety and native variety, respectively, by developing and extending technologies of manufacturing and handling rice milling machinery. 3. The head rice recovery of new variety at local milling plants has insignificant differences among milling systems, and was 54.8 percent on the average. With native variety, the recovery by friction type rice polisher was 0.9percent higher than that of friction-abrasive type polisher, and was 64.9 percent on the average. 4. The head rice recoveries of new variety and native can be elevated 5.1percent and 3.9percent, respectively, by the same stimulation above mentioned.

  • PDF

Acupuncture Analgesia : A Sensory Stimulus Induced Analgesia Observed by functional Magnetic Resonance Imaging (침의 진통효과: 체성감각신경자극으로 유도된 진통작용에 대한 기능성자기공명영상장치를 이용한 연구)

  • Cho, Zang-hee;Hwang, Seon-chool;Son, Young-don;Kang, Chang-ki;Wong, Edward K.;Bai, Sun-joon;Lee, Un-jung;Sung, Kang-kyung;Park, Tae-seok;Kim, Young-bo;Min, Hoon-ki;Oleson, Terry
    • Journal of Acupuncture Research
    • /
    • v.21 no.2
    • /
    • pp.57-71
    • /
    • 2004
  • Objective : Physiological evidence regarding acupuncture's effect in human patients is not yet well established, despite considerable evidence for its therapeutic efficacy. Besides target or disease specificity of acupuncture, acupuncture analgesia (AA) appears to be another large subclass that poses many questions, such as whether there is point specificity with respect to which acupoint is most effective for a particular condition. Methods : We observed brain activation with functional magnetic resonance imaging (fMRI) using a set of stimuli that consist of pain, pain following Meridian acupuncture, and pain following Sham acupuncture. Results : Among the new observations, the most interesting fact is that data sets of both Meridian acupuncture and Sham acupuncture show decreased activation of the same brain areas related to the pain processing signals. Present functional MRI study demonstrate two important biological observations that could elucidate AA mechanism in human participants: the effects of acupuncture occur through mediation of the higher brain areas. Sham acupuncture stimulation appears to be almost as effective as traditional Meridian acupoint stimulation, suggesting that acupuncture is not entirely point specific. Decreased activation in the limbic paleo cortical areas appears to be the probable neurological manifestation of AA and strongly implies that acupuncture stimulation inhibits the transmission of ascending pain signals to the higher cortical areas by the previously known descending pain inhibitory circuit. Conclusion : We, therefore, a hypothesized that this pain inhibitory circuit is initiated and mediated via the broad sense Hypothalamus Pituitary Adrenal (BS HPA) axis in conjunction to the "sensory stimulation."

  • PDF

Effectiveness of Transcranial Direct Current Stimulation(tDCS) on Upper Extremity Function in Stroke Patients : A Systematic Review and Meta-Analysis (뇌졸중 환자의 상지기능에 대한 경두개 직류자극술 효과 : 체계적 고찰 및 메타분석)

  • Won, Kyung-A;Yang, Min Ah;Park, Hae Yean;Park, Ji-Hyuk
    • Therapeutic Science for Rehabilitation
    • /
    • v.9 no.1
    • /
    • pp.7-23
    • /
    • 2020
  • Objective : The purpose of this article was to analyze the effects of tDCS on the recovery of upper limb function in stroke patients. Methods : We searched for papers published in journals between 2009 to 2018, using NDSL and RISS. A total 14 experimental research papers were selected for analysis. The quality of the 14 articles was evaluated using the PEDro scale and 12 articles were analyzed through the Comprehensive Meta Analysis 3.0 program. Results : All of the 14 articles that were systematically reviewed in this study were published in foreign journals. The effect sizes for upper extremity(U/Ex) strength and U/Ex motion were 0.19(small size effect) and 0.49(medium size effect) respectively. Furthermore, the effect sizes of anode mode and cathode mode were 0.71(large size effect) and 0.41(medium size effect), respectively. The effect size of U/Ex motion and the anode mode were statistically significant(p<0.05). Conclusion : We identified that tDCS can be a useful rehabilitation technique for stroke patients with limited upper body function. These findings are expected to help with suggestions for basic data on new rehabilitation techniques for stroke patients and the planning of effective interventions.

Development of stimulator for peripheral disturbance therapy using A variable Micro-electromagnetic (미약 전자기장을 이용한 말초장애 치료시스템 개발)

  • Kim, Soo-Byung;Lee, Seung-Wook;Shim, Ta-Kyu;Lee, Na-Ra;Lee, Yong-Heum
    • Journal of the Korea Institute of Information and Communication Engineering
    • /
    • v.14 no.5
    • /
    • pp.1209-1216
    • /
    • 2010
  • It has increased that peripheral disturbance(blood flow, nerve, Raynaud's phenomenon) and finger rheumatoid arthritis which is caused by the diabetic complications. To improve these pain issues, we proposed new method for the Finger Disease Therapy(FDT). In this paper, we manufactured solenoid cylindrical coil which was only for the FDT using a variable micro-electromagnetic. Also, we designed the Finger Disease Therapy System(FDTS) which could select three stimulation modes(N_pulse, S_pulse, N/S_pulse) and frequency(0.25hz, 0.5hz, 1hz). We used a Teslameter to measure magnetic flux inner solenoid, and measured magnetic flux as distance(0 ~ 3cm) inner solenoid with stimulation modes and frequency. In the results, magnetic flux was the highest in center of solenoid(0cm) for all stimulation modes. Also, the highest magnetic flux was measured as N_pulse(294.3mT), S_pulse(293.8mT) in 1Hz and N/S_pulse (275.4mT) in 0.25Hz, respectively. Therefore, we developed the FDTS using various pattern and intensity for finger diseases therapy, and checked therapy clinic application possibility of the FDTS as measuring magnetic flux inner solenoid.

Stimulation of bone formation by direct electrical current in an orthopedically expanded suture in the rat (백서의 악정형적으로 확장된 봉합부에서 직류 전류 자극의 골형성 촉진에 관한 연구)

  • Uysal, Tancan;Amasyali, Mihri;Olmez, Huseyin;Karslioglu, Yildirim;Gunhan, Omer
    • The korean journal of orthodontics
    • /
    • v.40 no.2
    • /
    • pp.106-114
    • /
    • 2010
  • Objective: The aim of this experimental study was to evaluate the effects of direct electrical current stimulation (DECS) on bone regeneration in response to an expansion of the inter-premaxillary suture in the rat. Methods: Sixteen 50 - 60 days old Wistar male rats were separated into two equal groups (control and experimental). Both groups were subjected to expansion, and 30-gram of force was applied to the maxillary incisors with helical-spring. In the experimental group, two metallic-screws were placed at lateral parts of the maxillary segments. Electrodes were connected to the screws. The device was activated with current adjustment to measure $10{\mu}A$ continuously and the current was monitored daily during the expansion and early-retention phase. Bone regeneration in the sutural area was histomorphometrically evaluated including new-bone area (${\mu}m^2$), bone perimeter (${\mu}m$), feret's diameter (${\mu}m$) and newly formed bone (%) parameters. Kruskal-Wallis rank and Mann-Whitney U tests were used for statistical evaluation at p < 0.05 level. Results: Statistical analysis showed significant differences between groups for all investigated histomorphometric parameters. New bone area (p = 0.002), bone perimeter (p = 0.004), feret's diameter (p = 0.002) and newly formed bone percentage (p = 0.002) measurements were significantly higher in the experimental group than the control group. Bone histomorphometric measurements revealed that bone architecture in the DECS group was improved. Conclusions: The application of DECS to an orthopedically expanded inter-premaxillary suture area during the early retention phase stimulated the formation of new bone.

An extension of new laser pulse atom-probe construction and time-of-flight mass spectrum of $H_2$ and He gas (A new laser pulse atom-probe 제작 및 $H_2$ 가스와 He 가스의 time-of-flight mass spectrum)

  • 송순달;홍남관
    • Journal of the Korean Crystal Growth and Crystal Technology
    • /
    • v.7 no.3
    • /
    • pp.465-472
    • /
    • 1997
  • An extension of new test methods for surfaces with an apparatus based on photon-induced desorption and ionisation in the electric field, is constructed and tested, It also investigates how to show the efficiency of the arrangement adsorbates $H_2$ and He on W(110). The field emitter temperature was 80 K. The wavelength of light used was 193 nm with field strengths between 10 and 50 V/nm. Many ion fragments($CO^+, He^+, H_2^^+, H_2O^+, W^{3+}\; and\; W^{2+}$) were produced by an electronic stimulation of the adsorbate with the help of a photon energy of 6.4 eV at He and $H_2$/W(110). A transient recorder enables the registration of the entire mass spectrum.

  • PDF

Analysis of Respiratory Gas by Training on Healthcare Indoor Bicycle (헬스케어용 실내 자전거 운동에 의한 호흡가스 분석)

  • Hong, Chul-Un;Kang, Hyung-Sub;Kim, Gi-Beum
    • Journal of Biomedical Engineering Research
    • /
    • v.30 no.2
    • /
    • pp.147-152
    • /
    • 2009
  • This study was conducted to observe the change of limbs stroke and respiration gas parameters in our new bicycle fitness system. We hypothesized that the variable force of left and right limbs might be effective for sensing stimulation in modified new unequal pedal bicycle system. It has been developed, which can provide visual information and different length of pedal with left and right limbs. Experimental results showed different activities between the left and right limbs where the activity of the left limb increased than that of right limb. Especially, the soleous muscle activity increased both in control and experimental groups by this training method. But oxygen and carbon dioxide partial pressures in respiratory gas increased during training method. These results suggest that acidosis of blood was led by this process. Consequently, this bicycle training is concluded that aerobic training could affect different limb activities. Finally, we expect that our new bicycle system will be effective for healthcare with proper balance between the left and right limbs.