• 대한전기학회:학술대회논문집
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• 대한전기학회 1999년도 하계학술대회 논문집 B
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• pp.963-965
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• 1999

A linear chromosome combined with a grid-based representation of the network and a new crossover operator allow the evolution of the architecture and the weights simultaneously. In our approach there is no need for a separate weight optimization procedure and networks with more than one type of activation function can be evolved. In this paper one evolutionary' strategy of a given dual neural controller was introduced and the simulation results were described in detail through applications to a stabilization control of an Inverted Pendulum System.

• Journal of Ginseng Research
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• 제44권3호
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• pp.373-385
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• 2020

Inflammation is an immune response that protects against pathogens and cellular stress. The hallmark of inflammatory responses is inflammasome activation in response to various stimuli. This subsequently activates downstream effectors, that is, inflammatory caspases such as caspase-1, 4, 5, 11, and 12. Extensive efforts have been made on developing effective and safe anti-inflammatory therapeutics, and ginseng has long been traditionally used as efficacious and safe herbal medicine in treating various inflammatory and inflammation-mediated diseases. Many studies have successfully shown that ginseng plays an anti-inflammatory role by inhibiting inflammasomes and inflammasome-activated inflammatory caspases. This review discusses the regulatory roles of ginseng on inflammatory caspases in inflammatory responses and also suggests new research areas on the anti-inflammatory function of ginseng, which provides a novel insight into the development of ginseng as an effective and safe anti-inflammatory herbal medicine.

• 한국문헌정보학회지
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• 제37권4호
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• pp.270-293
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• 2003

이 연구는 1989년에 설립된 이후 현재까지 본연의 소임을 다하지 못하고 있는 우리나라의 도서관정책위원회의 변천과정과 활동을 분석하여 문제점을 추출한 한 후, 우리 행정조직 상의 여러 위원회의 운영 행태와 미국ㆍ영국의 도서관정책위원회 분석결과에서 얻은 시사점을 참고하여, 이 위원회가 명실상부한 기능을 수행할 수 있기 위한 활성화 방안을 제시하였다.

• Carbon letters
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• 제5권2호
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• pp.51-54
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• 2004

Isotropic pitch-based carbon fiber was isothermally activated in $CO_2$ atmosphere. Structural parameters of the isotropic carbon fibers and activated carbon fibers (ACFs) were evaluated by X-ray diffraction (XRD). The $d_{002}$ and La of the carbon fibers were measured to be 4.04 ${\AA}$ and 23.6 ${\AA}$ and those of ACFs were 4.29 ${\AA}$ and 22.7 ${\AA}$, respectively, representing less ordered through activation process. The pores in the ACFs were characterized by BET, and they showed super-high specific surface area of maximum value 3,495 $m^2/g$ from average pore size of 8.3 ${\AA}$ at 59% burn-off. It was recognized that 8-9 ${\AA}$ was optimum range of pore size for efficient creation of high specific surface area. The average size of the pores formed at higher temperature ($1100^{\circ}C$) was larger than that of the pores formed at lower temperature ($900^{\circ}C$).

• 콘크리트학회논문집
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• 제13권3호
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• pp.237-243
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• 2001

본 논문에서는 플라이애시 콘크리트의 재령에 따른 변화를 예측하기 위한 모델식을 제시하고 그 모델식의 유효성을 검토하였다. 기존에 행해졌던 실험결과를 모델식을 이용하여 회귀분석한 후에 그 결과를 플라이애시 대체량과 물-시멘트비에 따라 분석하였다. 해석결과에 의하면 예측 모델식은 실험결과를 일정오차내에서 잘 모델링하였다. 그러나 물-시멘트비가 매우 작은 경우에는 플라이애시 대체량이 증가하면 실험값과 예측값의 오차가 조금 증가하는 경향을 나타내었다. 플라이애시 대체량이 증가할수록 한계상대압축강도의 크기가 증가하였고 초기 겉보기 활성에너지도 한계상대압축강도와 같이 플라이애시 대체량이 증가할수록 증가하였다. 0.40이하의 물-시멘트비에서는 한계상대압축강도와 겉보기 활성에너지의 크기가 일정하고 물-시멘트비가 0.40을 초과하면 물-시멘트비의 증가에 따라 한계상대압축강도와 겉보기 활성에너지가 조금씩 증가하였다.

• Communications for Statistical Applications and Methods
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• 제30권5호
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• pp.501-516
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• 2023

Knowledge distillation (KD) refers to extracting knowledge from a large and complex model (teacher) and transferring it to a relatively small model (student). This can be done by training the teacher model to obtain the activation function values of the hidden or the output layers and then retraining the student model using the same training data with the obtained values. Recently, relational KD (RKD) has been proposed to extract knowledge about relative differences in training data. This method improved the performance of the student model compared to conventional KDs. In this paper, we propose a new method for RKD by introducing a new loss function for RKD. The proposed loss function is defined using the area difference between the teacher model and the student model in a specific hidden layer, and it is shown that the model can be successfully compressed, and the generalization performance of the model can be improved. We demonstrate that the accuracy of the model applying the method proposed in the study of model compression of audio data is up to 1.8% higher than that of the existing method. For the study of model generalization, we demonstrate that the model has up to 0.5% better performance in accuracy when introducing the RKD method to self-KD using image data.

• The Korean Journal of Pain
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• 제22권1호
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• pp.1-15
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• 2009

Neuropathic pain is often refractory to intervention because of the complex etiology and an incomplete understanding of the mechanisms behind this type of pain. Glial cells, specifically microglia and astrocytes, are powerful modulators of pain and new targets of drug development for neuropathic pain. Glial activation could be the driving force behind chronic pain, maintaining the noxious signal transmission even after the original injury has healed. Glia express chemokine, purinergic, toll-like, glutaminergic and other receptors that enable them to respond to neural signals, and they can modulate neuronal synaptic function and neuronal excitability. Nerve injury upregulates multiple receptors in spinal microglia and astrocytes. Microglia influence neuronal communication by producing inflammatory products at the synapse, as do astrocytes because they completely encapsulate synapses and are in close contact with neuronal somas through gap junctions. Glia are the main source of inflammatory mediators in the central nervous system. New therapeutic strategies for neuropathic pain are emerging such as targeting the glial cells, novel pharmacologic approaches and gene therapy. Drugs targeting microglia and astrocytes, cytokine production, and neural structures including dorsal root ganglion are now under study, as is gene therapy. Isoform-specific inhibition will minimize the side effects produced by blocking all glia with a general inhibitor. Enhancing the anti-inflammatory cytokines could prove more beneficial than administering proinflammatory cytokine antagonists that block glial activation systemically. Research on therapeutic gene transfer to the central nervous system is underway, although obstacles prevent immediate clinical application.

• 한국신재생에너지학회:학술대회논문집
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• 한국신재생에너지학회 2011년도 춘계학술대회 초록집
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• pp.94.2-94.2
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• 2011

In this work, multi-functional groups, i.e., nitrogen and oxygen, contained microporous carbons (MF-MCs) were prepared by the one step carbonization of the poly(vinylidene chloride-co-acrylonitrile-co-methyl methacryalte) (PVDC-AN-MMA) without activation. The electrochemical performance of MF-MCs was investigated as a function of carbonization temperature. It was found that MF-MCs had a high specific surface area over $800m^2/g$ without additional activation, resulting from the micropore's formation by the release of chlorine groups. In addition, although functional groups decreased, specific surface area was increased with increasing carbonization temperature, leading to the enhanced electrochemical performance. The pore size of the carbon distributed mainly in small micropore of 1.5 to 2 nm, which was idal for aqueous electrolyte. Indeed, the unique microstructure features, i.e. high specific surface area and optimized pore size provided high energy storage capability of MF-MCs. These results indicated that the microporous features of MF-MCs lead to feasible electron transfer during charge/discharge duration and the presence of nitrogen and oxygen groups on the MF-MCs electrode led to a pseudocapacitive reaction.

• International Journal of Control, Automation, and Systems
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• 제6권3호
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• pp.453-459
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• 2008

The neural network is currently being used throughout numerous control system fields. However, it is not easy to obtain an input-output pattern when the neural network is used for the system of a single feedback controller and it is difficult to obtain satisfactory performance with when the load changes rapidly or disturbance is applied. To resolve these problems, this paper proposes a new mode to implement a neural network controller by installing a real object for control and an algorithm for this, which can replace the existing method of implementing a neural network controller by utilizing activation function at the output node. The real plant object for controlling of this mode implements a simple neural network controller replacing the activation function and provides the error back propagation path to calculate the error at the output node. As the controller is designed using a simple structure neural network, the input-output pattern problem is solved naturally and real-time learning becomes possible through the general error back propagation algorithm. The new algorithm applied neural network controller gives excellent performance for initial and tracking response and shows a robust performance for rapid load change and disturbance, in which the permissible error surpasses the range border. The effect of the proposed control algorithm was verified in a test that controlled the speed of a motor equipped with a high speed computing capable DSP on which the proposed algorithm was loaded.

• BMB Reports
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• 제34권2호
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• pp.95-101
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• 2001

Tissue transglutaminase (TGII, $G{\alpha}h$) belongs to a family of enzymes which catalyze post-translational modification of proteins by forming isopeptides via $Ca^{2+}$-dependent reaction. Although TGII-mediated formation of isopeptides has been implicated to play a role in a variety of cellular processes, the physiological function of TGII remains unclear. In addition to this Tease activity, TGII is a guanosine triphosphatase (GTPase) which binds and hydrolyzes GTP It is now well recognized that the GTPase action of TGII regulates a receptor-mediated transmembrane signaling, functioning as a signal transducer of the receptor. This TGII function signifies that TGII is a new class of GTP-binding regulatory protein (G-protein) that differs from "Classical" heterotrimeric G-proteins. Regulation of enzyme is an important biological process for maintaining cell integrity. This review summarizes the recent development in regulation of TGII that may help for the better understanding of this unique enzyme. Since activation and inactivation of GTPase of TGII are similar to the heterotrimeric G-proteins, the regulation of heterotrimeric G-protein in the transmembrane signaling is also discussed.