• Title/Summary/Keyword: neurophysiology

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The Relation of Restless Legs Syndrome with Diseases of Peripheral Nerves (말초신경질환과 하지불안증후군의 연관성에 관하여)

  • Hong, Yoon-Ho
    • Annals of Clinical Neurophysiology
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    • v.10 no.2
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    • pp.101-103
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    • 2008
  • Many neurologists, particularly whose subspecialty is in peripheral neurology, may agree that patients with peripheral neuropathy often complain of the "restless legs" symptoms. These symptoms seem to share the typical features of the so-called "restless legs syndrome (RLS)", i.e., unpleasant sensations in the leg/feet, worsening in the evening or at night, and the partial relief of the positive sensory symptoms by the movements such as walking, shaking or rubbing. In fact, a higher incidence of RLS was reported among the neuropathic patients, and peripheral neuropathy was found to be more prevalent in patients with RLS than in general population. Moreover, RLS share many risk factors with peripheral neuropathy such as diabetes, uremia, amyloidosis and cryoglobulinemia, which suggests that peripheral neuropathy may play a pathophysiologic role in the development of RLS.

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Throtoxic Periodic Paralysis without Hypokalemia (저칼륨증 없이 나타난 갑상샘중독주기마비 1예)

  • Kim, Hyeyun;Kim, Sung-Min;Park, Jong-Ho;Cho, Joong-Yang
    • Annals of Clinical Neurophysiology
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    • v.10 no.2
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    • pp.119-122
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    • 2008
  • Thyrotoxic periodic paralysis (PP) is the most common acquired form of PP in Asian populations, and its cardinal and biochemical abnormality is hypokalemia. We describe a 39-year-old man who had acute bilateral limb motor weakness and paresthesia, and showed normokalemia during attack. Thyroid studies showed subclinical thyrotoxic Goiter. Control of the hyperthyroidism nearly eliminated his PP. Regardless of normokalemia, our patient might be a case of hypokalemic PP because of improvement from anti-thyroid medication.

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A Case of Mills' Syndrome (Mills증후군 1예)

  • Kim, Do-Eui;Lee, Kyung-Bok;Roh, Hakjae;Ahn, Moo-Young
    • Annals of Clinical Neurophysiology
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    • v.10 no.2
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    • pp.116-118
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    • 2008
  • Mills' syndrome is rare clinical syndrome described in 1900 by Mills, namely ascending (or less often, descending) progressive hemiplegia. Mills' syndrome could be considered as a variant of primary lateral sclerosis (PLS) or amyotrophic lateral sclerosis (ALS), but is still controversial. According to clinical course, imaging and electrophysiological findings, our case is more compatible with Mills' syndrome rather than PLS or ALS. To our knowledge, this is the first report of Mills' syndrome in Korea.

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Colchicine-induced Acute Myopathy in a Renal Recipient (신이식 환자에서 Colchicine에 의해 유발된 급성 근육병증 1예)

  • Kim, Jin-Soo;Shin, Chae-Won;Yang, Huijun;Kim, Jun Soon;Hong, Yoon-Ho
    • Annals of Clinical Neurophysiology
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    • v.10 no.2
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    • pp.112-115
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    • 2008
  • Colchicine is a drug used for the treatment of acute gouty arthritis or various autoimmune diseases. Gastrointestinal adverse effects such as abdominal pain and vomiting are the common side effects of the drug, but rarely myopathy has been reported to occur particularly in renal recipients who were treated concomitantly with immunosuppressants. Herein, we report a case who presented with acute myopathy after treated with colchicine for acute gouty arthritis.

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