• 제목/요약/키워드: nephrectomy

검색결과 113건 처리시간 0.027초

개에서 편측성 난소낭종의 방사선학적 및 초음파학적 진단 2례 (Radiographic and Ultrasonographic Diagnosis of Unilateral Ovarian Cysts)

  • 이기창;최민철
    • 한국임상수의학회지
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    • 제19권3호
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    • pp.367-370
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    • 2002
  • A female, 14-year-old mixed dog weighing 4 kg and a female,8-year-old schnauzer dog weighing 6 kg showing vaginal discharges and vomiting for a few weeks were examined for the preoperative check of anterior cruciate ligament rupture and the recheck after the surgery of nephrectomy. There were no distinct abnormal signs except for the increased CBC at schnauzer dog on blood chemistry analysis. Radiographic and ultrasonographic findings were a large abdominal mass and a cyst-like hypoechogenic or anechogenic cavitary lesion on the ovary region. These findings were consistent with an ovarian cyst. Thereafter highly suspected ovarian cysts by diagnostic imaging were supported by high estrogen concentration on hormonal assay and the results of Pathologic examination as the unilateral ovarian cysts with secondary pyometra.

A renal oncocytoma in a Maltese dog with renal cysts

  • Kim, Jong-uk;Park, Jinsung;Kim, Gonhyung;Chang, Dongwoo;Ahn, Byeongwoo
    • 대한수의학회지
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    • 제59권1호
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    • pp.47-49
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    • 2019
  • A renal oncocytoma was diagnosed in an 8-year-old female Maltese dog with a history of renal cysts. Tumor cells were not detected until six months after observation of renal cysts. Nephrectomy was performed to treat the neoplasia. Tumor-like masses with numerous nodules were observed in the inner surface of cysts present in the caudal part of the left kidney. Histologically, the tumor consisted of cells with abundant eosinophilic cytoplasm. The diagnosis was based on histological features, periodic acid-Schiff reaction, and immunohistochemical cytokeratin staining. Based on a literature review, this is the first canine renal oncocytoma case reported in Korea.

저단백식이의 투여가 만성신부전증의 진행에 미치는 영향에 관한 실험적 연구 (Effects of Dietary Protein on the Progression of Early Chronic Renal Failure in Subtotally Nephrectomizid Rats)

  • 김교순;김기혁;김상윤;강용주;맹원재
    • Childhood Kidney Diseases
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    • 제3권1호
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    • pp.64-71
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    • 1999
  • 목 적 : 초기만성신부전증에서 저단백식이의 투여가 만성신부전의 진행속도 및 혈압조절에 어떠한 영향을 미치는 지를 알기 위함이다. 방 법 : 5/6 신절제술로 만성 신부전을 유발시킨 백서를 수술 제 7일부터 무작위로 enalapril을 투여하지 않은 군과 enalapril 투여군 (식수 1L 당 50 mg)으로 나누고 각군을 정상단백식이군 ($18.5\%$ 단백식이), 저단백식이군($6\%$단백식이)으로 나누어 비교하여 보았다. 신절제술후 4주, 12주, 16주에 단백뇨의 변화, 잔여 신장무게, 신 조직의 mesangial matrix expansion score 및 morphometric analysis로 분석한 사구체용적의 변화를 비교 분석하여 다음과 같은 결과를 얻었다. 결 과 : 1) 정상단백식이군 및 저단백식이군은 신절제술후 혈압이 올라가기 시작하여 지속적인 고혈압소견을 보였다 (정상단백식이군; 4주 $147{\pm}6$mmHg, 8주 $175{\pm}11$mmHg, 12주 $180{\pm}6$mmHg, 16주 $200{\pm}6$ mmHg: 저단백식이군; 4주 $140{\pm}8$mmHg, 8주 $162{\pm}5$mmHg, 12주 $171{\pm}6$mmHg, 16주 $184{\pm}11$mmHg). Enalapril 투여군은 식이의 단백량과 관계없이 신절제술후 8주부터 혈압이 조절되기 시작하였다. 2) 16주째 저단백식이군의 24시간 뇨단백은 $74{\pm}15$mg으로 정상단백식이군 ($101{\pm}15$mg)보다 의의있게 적었다. (P<0.05). Enalapril 투여군도 저단백식이의 경우 $42{\pm}12$mg 으로. 정상단백식이($67{\pm}15$mg) 보다 의의있게 적었다. (P<0.05). 3) 신절제술후 16주째 크레아티닌 청소율은 정상단백식이군 $1.40{\pm}0.13$ ml/min, 저단백식이군은 $1.57{\pm}0.11$ml/min, enalapril 정상단백식이군은 $1.10{\pm}0.17$ml/min, enalapril 저단백식이군은 $1.37{\pm}0.14$ml/min 이었다. (P=NS). 4) 저단백식이군의 잔여 신장무게의 증가는 정상단백시이군의 신장 무게의 증가에 비해 의의있게 낮았다. (저단백식이군; 4주 $1.33{\pm}0.04g$, 12주 $1.45{\pm}0.05g$, 16주 $1.44{\pm}0.16g$: 정상단백이군; 4주 $1.58{\pm}0.19g$, 12 주$1.79{\pm}0.15g$, 16주 $1.99{\pm}0.12g$, P<0.05). 16주에 관찰한 enalapril 투여군의 신장무게를 보면 저단백식이, 정상단백식이에 따른 차이는 없었다. 5) 12주, 16주째 저단백식이군의 mesangial matrix expansion score은 정상단백식이군보다 의의있게 감소되었다. (저단백식이군; 12주 $1.91{\pm}0.02$, 16주 $1.90{\pm}0.02$; 정상단백식이군 ; 12주 $2.29{\pm}0.09$, 16주 $2.55{\pm}0.16$, P<0.05). Enalapril 투여군의 mesangial matrix expansion score는 식이의 단백량에 따른 차이는 없었다. 6) 16주째 저단백식이군의 사구체용적은 정상단백식이군보다 의의있게 감소되었다 (16주, 저단백식이군; $1.17{\pm}0.19{\times}10^6{\mu}m^3$ ; 정상단백식이군; $1.98{\pm}0.16{\times}10^6{\mu}m^3$, P<0.05). Enalapril 투여군의 사구체용적은 저단백식이의 경우 정상식이 때 보다 의의있는 감소를 보였다 (16주, 저단백식이군; $1.19{\pm}0.17{\times}10^6{\mu}m^3$: 정상단백식이군; $1.81{\pm}0.22{\times}10^6{\mi}m^3$, P<0.05). 결 론 : 항고현압제를 쓰지 않은 군에서의 저단백식이의 효과는 매우 현저하였고 항고혈압제를 쓴 군에서는 저단백식이와 정상단백식이의 차이가 없었다. 따라서 저단백식이와 항고혈압제는 각각 신조직 손상의 진행을 확실히 지연시키나 두가지를 같이 병용하면 각각 지연시키는 것에 비하여는 additional effect가 미미하였다. 그러나 혈압 조절은 저단백식이로는 만족할만하지 못하고 항고혈압제에 의한 혈압조절이 도움이 되므로_ 만성신부전 환자에서 저단백식이와 항고혈압제의 병용요법이 필요한 것으로 사료된다.

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가정간호 서비스 질 평가를 위한 도구개발연구 (A basic research for evaluation of a Home Care Nursing Delivery System)

  • 김모임;조원정;김의숙;김성규;장순복;유호신
    • 가정간호학회지
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    • 제6권
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    • pp.33-45
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    • 1999
  • The purpose of this study was to develop a basic framework and criteria for evaluation of quality care provided to patients with the attributes of disease in the home care nursing field, and to provide measurement tools for home health care in the future. The study design was a developmental study for evaluation of hospital-based HCN(home care nursing) in Korea. The study process was as follows: a home care nursing study team of College of Nursing. Yonsei University reviewed the nursing records of 47 patients who were enrolled at Yonsei University Medical Center Home Care Center in March, 1995. Twenty-five patients were insured at that time, were selected from 47 patients receiving home care service for study feasibility with six disease groups; Caesarean Section (C/S), simple nephrectomy, Liver cirrhosis(LC), chronic obstructive pulmonary disease(COPD), Lung cancer or cerebrovascular accident(CVA). In this study, the following items were selected : First step : Preliminary study 1. Criteria and items were selected on the basis of related literature on each disease area. 2. Items were identified by home care nurses. 3. A physician in charge reviewed the criteria and content of selected items. 4. Items were revised through preliminary study offered to both HCN patients and discharged patients from the home care center. Second step : Pretest 1. To verify the content of the items, a pretest was conducted with 18 patients of which there were three patients in each of the six selected disease groups. Third step : Test of reliability and validity of tools 1. Using the collected data from 25 patients with either cis, Simple nephrectomy, LC, COPD, Lung cancer, or CVA. the final items were revised through a panel discussion among experts in medical care who were researchers, doctors, or nurses. 2. Reliability and validity of the completed tool were verified with both inpatients and HCN patients in each of field for researches. The study results are as follows: 1. Standard for discharge with HCN referral The referral standard for home care, which included criteria for discharge with HCN referral and criteria leaving the hospital were established. These were developed through content analysis from the results of an open-ended questionnaire to related doctors concerning characteristic for discharge with HCN referral for each of the disease groups. The final criteria was decided by discussion among the researchers. 2. Instrument for measurement of health statusPatient health status was measured pre and post home care by direct observation and interview with an open-ended questionnaire which consisted of 61 items based on Gorden's nursing diagnosis classification. These included seven items on health knowledge and health management, eight items on nutrition and metabolism, three items on elimination, five items on activity and exercise, seven items on perception and cognition, three items on sleep and rest, three items on self-perception, three items on role and interpersonal relations, five items on sexuality and reproduction, five items on coping and stress, four items on value and religion, three items on family. and three items on facilities and environment. 3. Instrument for measurement of self-care The instrument for self-care measurement was classified with scales according to the attributes of the disease. Each scale measured understanding level and practice level by a Yes or No scale. Understanding level was measured by interview but practice level was measured by both observation and interview. Items for self-care measurement included 14 for patients with a CVA, five for women who had a cis, ten for patients with lung cancer, 12 for patients with COPD, five for patients with a simple nephrectomy, and 11 for patients with LC. 4. Record for follow-up management This included (1) OPD visit sheet, (2) ER visit form, (3) complications problem form, (4) readmission sheet. and (5) visit note for others medical centers which included visit date, reason for visit, patient name, caregivers, sex, age, time and cost required for visit, and traffic expenses, that is, there were open-end items that investigated OPD visits, emergency room visits, the problem and solution of complications, readmissions and visits to other medical institution to measure health problems and expenditures during the follow up period. 5. Instrument to measure patients satisfaction The satisfaction measurement instrument by Reisseer(1975) was referred to for the development of a tool to measure patient home care satisfaction. The instrument was an open-ended questionnaire which consisted of 11 domains; treatment, nursing care, information, time consumption, accessibility, rapidity, treatment skill, service relevance, attitude, satisfaction factors, dissatisfaction factors, overall satisfaction about nursing care, and others. In conclusion, Five evaluation instruments were developed for home care nursing. These were (1)standard for discharge with HCN referral. (2)instrument for measurement of health status, (3)instrument for measurement of self-care. (4)record for follow-up management, and (5)instrument to measure patient satisfaction. Also, the five instruments can be used to evaluate the effectiveness of the service to assure quality. Further research is needed to increase the reliability and validity of instrument through a community-based HCN evaluation.

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만성신부전 백서에서 항고혈압제의 종류에 따른 신부전의 진행과 사구체의 형태학적 변화 (Effects of Antihypertensive Drugs on Renal Function and Glomerular Morphology in Chronic Renal Failure Rats)

  • 홍성진;김교순;김병길;박경화;김기혁
    • Childhood Kidney Diseases
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    • 제6권2호
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    • pp.169-177
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    • 2002
  • 목적 : 만성신부전은 신장에 병적 손상이 있어 지속적으로 신기능이 저하되어 말기신부전에 이르게 된다. 만성신부전의 진행을 지연시킬 수 있는 인자 중 혈압조절이 중요한 것으로 알려져 있다. 저자들은 부분 신절제를 이용하여 만성신부전을 유발시킨 후 항고혈압제로 enalapril과 nicardipine을 투여하여 만성신부전의 진행에 미치는 영향을 조사하였다. 대상 및 방법 : 백서에서 5/6 신절제술로 만성신부전을 유발시킨 후 무작위로 대조군, enalapril 투여군(E군), nicardipine 투여군(N군)으로 나누어 4주 간격으로 꼬리 동맥압을 측정하고 12주째 24시간 소변 단백량과 creatinine배설량, 혈청 creatinine을 측정한 후 희생시켜 신조직을 광학현미경과 전자현미경으로 관찰하여 사구체의 형태학적 소견을 조사하였다. 결과 : 1. 신절제 후 대조군은 지속적으로 혈압이 증가하였으나 E군과 N군에서는 정상 혈압이 유지되었다. 2. 12주째 E군에서 요단백량은 대조군과 N군에 비하여 유의하게 적었다. 3. 12주째 조사한 신장의 형태계측학적 검사에서 E군과 N군 모두에서 mesangium의 증식이 대조군에 비하여 유의하게 적었으나 사구체 용적은 E군에서만 대조군에 비하여 적었다. 4. 대조군, E군, N군간의 상피세표 족돌기의 형태학적 변화의 차이는 없었다. 결론 : 부분 신절제로 유발한 만성신부전 백서에서 enalapril, nicardipine 모두 고혈압을 예방하였으나 enalpril 투여군에서 단백뇨의 감소와 신병변 발생 예방 효과가 우수하였으며, 상피세포 족돌기의 변화에는 차이가 없었다.

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하대정맥과 우심방의 종양혈전을 동반한 신평활근육종 - 1예 보고 - (Renal Leiomyosarcoma with an Extension of the Tumor Thrombi into the IVC and the RA -One of case -)

  • 정기천;이철범;전순호;김상헌;김혁;정원상;김영학;강정호
    • Journal of Chest Surgery
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    • 제36권12호
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    • pp.970-974
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    • 2003
  • 하대정맥과 우심방의 종양혈전을 동반한 신세포암종은 지난 10년 동안 근치적 신절제술과 함께 체외순환을 이용한 종양혈전 제거술로 예후가 많이 증진되었다. 우리는 30세 여자에서 우신평활근육종과 종양혈전이 신정맥 상부의 하대정맥과 우심방까지 성장하고 혈액혈전으로 신정맥 하부의 하대정맥과 양측 장골정맥이 폐쇄된 1예를 진단하고 근치적 우신절개술 후 체외순환을 이용한 초저체온 순환 정지하에서 하대정맥과 우심방을 절개하여 종양혈전과 혈액 혈전 모두를 제거하였다. 수술 12개월 후 후복막강과 하대정맥의 국소적 재발로 우심방까지 성장한 종양을 다시 제거하였다. 환자는 두 번째 수술 11개월 후 폐 전이 및 간정맥에서 종양이 재발하여 우심방과 우심실까지 성장하여 사망하였다.

성인에서 발생한 중배엽성 신종의 폐전이 1예 (A Case of Lung Metastasis of Mesoblastic Nephroma in Adulthood)

  • 문진욱;김길동;신동환;한창훈;정재호;박무석;정상윤;이재혁;김영삼;김세규;김성규;장준
    • Tuberculosis and Respiratory Diseases
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    • 제55권4호
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    • pp.402-407
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    • 2003
  • 저자 등은 성인에서 드물며, 또한 국내에서 원격전이를 일으킨 예가 보고된 바 없는 중배엽성 신종이 35세 여자 환자에서 발생하여 신적출술 7년 후 폐전이로 하나의 큰 종괴를 형성한 증례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

Endothelium-dependent Contraction of Aorta in One-kidney, One-clip Goldblatt Hypertensive Rat

  • Jeon, Byeong-Hwa;Lee, Kug-Hee;Kim, Hoe-Suk;Kim, Se-Hoon;Chang, Seok-Jong
    • The Korean Journal of Physiology
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    • 제30권2호
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    • pp.269-278
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    • 1996
  • The mechanism of impaired endothelium-dependent relaxation in the aorta of one-kidney, one clip Goldblatt hypertensive (1K,1C-GBH) rats was investigated. 8 week-old Wistar-Kyoto (WKY) rats were made hypertensive by left renal artery stenosis with contralateral nephrectomy. Endothelium-dependent relaxation was significantly reduced in 1K,1C-GBH rats as compared with WKY rats. However, the relaxation by sodium nitroprusside in 1K,1C-GBH rats was not reduced as compared with WKY rats. The impairment of endothelium-dependent relaxation in 1K,1C-GBH rats was partially restored by the pretreatment of indomethacin or SQ29548. When the nitric oxide production was inhibited by L-nitroarginine methyl ester, acetylcholine (ACh) induced a endothelium-dependent contraction that was greater in 1K,1C-GBH rats than in WKY rats. Endothelium-dependent contraction by ACh was completely abolished by indomethacin or SQ29548. However, imidazole, tranylcypromine and superoxide dismutase did not affect the endothelium-dependent contraction in 1K,1C-GBH rats. These results suggest that impaired endothelium-dependent relaxation in the 1K,1C-GBH rats might be due to the simultaneous release of EDCF, and that prostaglandin B2 may be involved as a mediator of endothelium-dependent contraction.

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한국흑염소에서의 실험적 신증의 임상병리학적 연구 (Clinicopathological Studies on the Experimentally Induced Nephrosis of Korea Black Goats)

  • 최희인;성재기;남치주;이창우;이경갑
    • 한국임상수의학회지
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    • 제6권2호
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    • pp.261-268
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    • 1989
  • In order to study the effects of administration of neomycin on the kidney of Korean black goats, 4.5(group A), 9(group B) or 14(group C) mg/kg, body weight of neomycin was injected intramuscularly turice a day for 84 days. On day 31, unilateral nephreotomy was performed in one animal of each group. The results were as follows: Serum neomycin concentrations were 8.7, 13.8, and 20.2 ${\mu}$g/ml 12 hours after injection. Serum BUN and creatinine concentration in nephreotomized goats, regardless of dosage, rapidly increased and came to peak on 3 days after, and then began to decrease to normal range, gradually, In non-nephrectomized goats, regardless of dosage, there was no notable change. In nephreotomized goats, PSP Tl/2 was delayed to the utmost 1 day after nephrectomy, regard-less of dosage, and then began to decrease to normal range, gradually in non-nephrectomized goats, there was not notable change in PSP T$\frac{1}{2}$. The intact kidney was markedly enlarged compared with the kidney of non-nephrectomized goats, but there was no microscopic change. It is concluded that administration of neomycin up to 14mg/kg body weight twice a day for 84 days was not nephrotoxic to the Korean black goats.

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만성신부전(慢性腎不全)의 고혈압(高血壓)에서 Furosemide 정주(靜注)에 대(對)한 Renin 반응(反應) (Renin Response to Intravenous Furosemide in Hypertension of Chronic Renal Failure)

  • 최강원
    • 대한핵의학회지
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    • 제12권1호
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    • pp.9-16
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    • 1978
  • It has been suggested that plasma renin activity (PRA) and its response to volume depletion may be abnormal in that it shows little or exaggerated change in patients with chronic renal failure and hypertension. Intravenous furosemide stimulation test was performed in 46 control subjects and 51 patients with chronic renal failure and/or malignant hypertension in order to evaluate PRA response. In contrast to the consistent increase in PRA in control subjects (from $2.5{\pm}1.95\;to\;4.5{\pm}2.51ng/ml/hr$), no consistent increase was observed in patients with chronic renal failure, especially in those who showed favorable response to antihypertensive therapy (from $2.5{\pm}2.21\;to\;2.9{\pm}2.46ng/ml/hr$). But poor responder to antihypertensive treatment showed considerably higher PRA before and after furosemide stimulation (from $4.9{\pm}1.96\;to\;6.4{\pm}1.71ng/ml/hr$) than the responder group did. Moreover, this group seemed to retain the ability to increase PRA in response to intravenous furosemide stimulation. Thus it became apparent that responder group was unable to increase PRA normally in response to furosemide as well as volume depletion, while poor responder seemed to retain that ability. Thus intravenous furosemode may serve as a convenient way to differenfiate those who might be benefited by conservative antihypertensive measures from those who would require more drastic measures such as bilateral nephrectomy for their optimal blood pressure control.

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