• Neonatal Medicine
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• 제28권1호
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• pp.36-40
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• 2021

Gastric volvulus in neonates is an extremely uncommon disorder, which is challenging to diagnose because of its non-specific clinical manifestations. Early diagnosis of gastric volvulus is important to avoid life-threatening complications, such as gastric ischemia, necrosis, and perforation. A definitive diagnosis could be made with radiological upper gastrointestinal series. In this report, we present two cases of neonate gastric volvulus, which were confirmed by radiological upper gastrointestinal series, and the patients underwent surgical treatment.

• 한국임상약학회지
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• 제23권2호
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• pp.167-174
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• 2013

Objective: The study evaluated the impact of pharmacist inventions with the implementation of pharmacistinvolved nutritional support service at neonate intensive care unit in a tertiary teaching hospital. Method: A retrospective and observational study was carried out. The total of 58 infants in neonate intensive care unit was enrolled between January 2011 and October 2012. The pharmacist-involved total parenteral nutritional program was initiated in June of 2012. During the program, pharmacist actively participated in the multidisciplinary round with performing the interventions from reviewing the amount of combined total parenteral nutrition and enteral fluid intakes, the amount of total calories, the glucose infusion rate, and the amounts of proteins per weight in kilogram. The outcome was compared with the results from the control group which reflected the prior period of the program initiation. Result: The number of days of regaining birth weight was significantly shorter (14.5 vs. 19 days, p=0.049) and the percentage of total calorie days with >90 kcal/kg/day was increased significantly (40 vs. 13%, p=0.008) in intervention group compared to the values in control group. In addition, the total mean daily caloric intakes ($84.78{\pm}13.8$ vs. $74.86{\pm}15.36$ kcal/kg/day, p=0.018) was significantly higher in intervention group than those results in control group. There were no significant differences in safety parameters between two groups related to nutritional services of necrotizing enterocolitis, intraventricular hemorrhage, proven sepsis, and also parenteral nutrition-induced hepatotoxicity. Conclusion: Pharmacist-involved total parenteral nutrition managed program was successfully implemented. The outcome showed the improved effectiveness of total parenteral nutrition with pharmacist interventions and no differences in adverse reactions. This could prove the positive effects of pharmacist involvement on nutritional therapy for neonate population.

• Clinical and Experimental Pediatrics
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• 제49권9호
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• pp.1005-1009
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• 2006

아가미틈새(branchial cleft) 낭종은 흔히 경부측면에 위치하나, 아가미틈새 낭종의 조직학적 소견을 보이는 낭종이 비전형적인 위치에서 발견되기도 한다. 갑상샘의 아가미틈새양(branchial cleft-like) 낭종은 이제까지 보고된 14례 중 7세 여아에서 발견된 1례를 제외하고는 모두 성인에서 발견되었다. 저자들은 좌측경부의 종물을 주소로 내원한 신생아에서 초음파 검사, 컴퓨터 단층촬영, 병리조직학 검사를 통하여 진단된 갑상샘의 아가미틈새양 낭종 1례를 경험하였기에 보고하는 바이다.

• Journal of Chest Surgery
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• 제47권4호
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• pp.398-401
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• 2014

Severe tricuspid regurgitation resulting from a flail leaflet is a rare cause of neonatal cyanosis. We report a neonate with profound cyanosis and severe tricuspid regurgitation caused by a rupture of the papillary muscle supporting the anterior leaflet, without other structural heart defects. Ductal patency could not be established. The repair of the tricuspid valve was performed after initial stabilization by using extracorporeal membrane oxygenation.

• Neonatal Medicine
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• 제25권3호
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• pp.126-130
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• 2018

Parkes Weber syndrome is a rare congenital vascular anomaly, related to the RAS p21 protein activator 1 (RASA1) gene. It is characterized by capillary cutaneous malformations, bony and soft tissue hyperplasia, and multiple arteriovenous fistulas throughout the affected upper or lower extremity. These arteriovenous fistulas can be associated with life-threatening complications such as bleeding, thrombosis, and high output heart failure. In this report, we present a neonate who had a disproportionately hypertrophied left upper limb with port-wine stain, dystrophy of the left humerus, and hypertrophy of the left clavicle on X-ray, and arteriovenous malformation and massive dilatation of the left subclavian artery on magnetic resonance angiography. Exome sequencing analysis revealed a novel heterozygous splicing mutation (c.1776+2T>A) in the RASA1 gene. To the best of our knowledge, this report is the first case of RASA1-related Parkes Weber syndrome in Korea.

• Journal of Korean Neurosurgical Society
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• 제44권2호
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• pp.98-100
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• 2008

We report a very rare case of a rapidly calcified chronic epidural hematoma (EDH) in a neonate. A 26-day-old female infant was referred to us from a regional hospital because of drowsy mentality and a seizure attack. She was delivered through caesarian section because normal spontaneous vaginal delivery was prolonged and failed. At birth, mild scalp swelling was found on the right frontal area. Scalp swelling was spontaneously resolved and she was discharged without any problems. On the 25th day after her birth, the baby presented with drowsiness and hypotonia following a generalized tonic-clonic seizure. Magnetic resonance imaging (MRI) and a computed tomography (CT) scan revealed a chronic EDH that had a thick layer of calcification. A small burr-hole trephination was performed and a single silastic drainage catheter was inserted. After the operation, a total of 12 ml of liquefied hematoma was drained, and the patient's mentality improved from drowsiness to alertness. The patient was asymptomatic when discharged.

• Neonatal Medicine
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• 제16권1호
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• pp.94-98
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• 2009

저자들은 태반에서 L. monocytogenes 균이 동정된 무증상 산모에서 출생한 $26^{+4}$주, 930g 초극소 저체중 출생아에서 리스테리아 조기 패혈증 및 폐렴이 발생하여 항생제 치료 후 호전된 1례를 경험하여 이를 문헌 고찰과 함께 보고하는 바이다.

• Clinical and Experimental Pediatrics
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• 제48권5호
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• pp.569-571
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• 2005

저자들은 수막구균성 뇌수막염으로 치료받던 환아에서 순조로운 치료 경과를 보이던 중 장관 폐쇄 증상이 발현되어 유미성 장간막 낭종으로 진단된 후 수술을 통해 치료된 신생아를 경험하였기에 그 임상 경과를 문헌고찰과 함께 보고하는 바이다.

• Clinical and Experimental Pediatrics
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• 제46권8호
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• pp.821-825
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• 2003

저자들은 생후 42일에 발열 및 감기 증상으로 내원한 환아에게서 발견된 선천성 말라리아를 클로로퀸을 사용하여 후유증 없이 치료할 수 있었다. 산모가 말라리아에 걸릴 경우 전신을 순환하는 말라리아 원충이 태반에 감염을 일으킬 수 있으나 대부분은 태아 순환을 통하지 않는 점으로 볼 때 본 예는 그 의의가 크다고 볼 수 있다. 최근 말라리아 환자 발생이 증가됨에 따라 임산부의 말라리아 뿐만 아니라 선천성 말라리아의 가능성도 있으므로 이에 대한 예방 및 치료에 대한 대책이 필요할 것으로 여겨진다.

• Clinical and Experimental Pediatrics
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• 제52권2호
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• pp.261-264
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• 2009

장 중복낭종은 드문 선천성 기형 질환으로 구강에서 항문까지 어느 곳에서나 발견할 수 있고 장관과 교통하기도 한다. 특히 맹장의 장 중복낭종은 더욱 드문 질환이다. 이들은 구토나 반복적인 복통과 위장관 출혈 및 변비 등의 증상으로 급성 장폐색을 발생시키며 생후 2년내 80%에서 발견된다. 저자들은 신생아에서 맹장의 장 중복낭종에 의해 발생한 장 폐색 1예를 경험하였기에 보고하고자 한다.