• Title/Summary/Keyword: neoline

Search Result 3, Processing Time 0.022 seconds

Diterpene Alkaloids from Kyong-Po Buja (Processed Aconitium carmichaeli) (경포부자의 다이테르펜 알칼로이드 성분)

  • Choi, Sang-Zin;Kwon, Hak-Cheol;Min, Yong-Deak;Lee, Sung-Ok;Kim, Kyung-Ran;Choi, Sang-Un;Son, Kun-Ho;Kang, Sam-Sik;Lee, Kang-Ro
    • Korean Journal of Pharmacognosy
    • /
    • v.33 no.3 s.130
    • /
    • pp.187-190
    • /
    • 2002
  • Three diterpene alkaloids, songorine (1), neoline (2), N-deethylneoline (3), were isolated from Kyong-Po Buja (Processed Aconitium carmichaeli, Ranunculaceae) which was used as Chinese traditional medicine with analgesic, anti-inflammatory and cardiotonic activity. Their structures were established by chemical and spectroscopic methods.

Two new acylated neoline derivatives from Aconiti Tuber

  • Shim, Sang-Hee;Kim, Ju-Sun;Kang, Sam-Sik
    • Proceedings of the PSK Conference
    • /
    • 2002.10a
    • /
    • pp.388.1-388.1
    • /
    • 2002
  • Aconiti Tuber (Aconitum spp. tuber, Ranunculaceae) which contains bioactive but toxic alkaloids has been used as analgesic. cardiotonic, diuretic. and stimulant. We have previously reported two new C-19 norditerpenoid alkaloids and five known norditerpenoid alkaloids. Further study has now led to the isolation of two new norditerpenoid alkaloids. 14-O-anisoylneoline and 14-O-veratroylneoline. (omitted)

  • PDF

Alkaloidal Constituents from Aconitum jaluense

  • Shim, Sang-Hee;Kim, Ju-Sun;Kang, Sam-Sik;Son, Kun-Ho;Bae, Ki-Hwan
    • Archives of Pharmacal Research
    • /
    • v.26 no.9
    • /
    • pp.709-715
    • /
    • 2003
  • Aconitum jaluense Komar. (Ranunculaceae) is one of the Aconitum plants growing in Korean peninsula. An investigation of the alkaloidal constituents of this species led to the isolation of seven $C_{19}$-norditerpenoid and a $C_{20}$-diterpenoid alkaloid. Three of them have been identified as neoline, mesaconitine, and hypaconitine, which were isolated from this plant collected from Mt. Bultasan in the north part. The other five alkaloids were determined as lipomesaconitine, lipohypaconitine, 15$\alpha$-hydroxyneoline, hokbusine A, and napelline, which have not been found in this plant. Structures of those alkaloids were determined on the basis of their spectral data. It is of interest to note that a comparison of the present work and the previous report showed some differences in the alkaloidal contents.