• 인간식물환경학회지
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• 제22권1호
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• pp.99-107
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• 2019

The purpose of this study was to find out the effects of five senses activities in forests on the reduction or mitigation of daily stress using various forest healing factors such as water, sunlight, topography, phytoncide, landscape, sound, fragrance, etc. The subjects of this study were 40 young children aged 5 in an early childhood education institution located in Cheongju. The children were divided into two groups: 20 in the experimental group and 20 in the control group. The experimental group participated in the program of five senses activities in the forest in total of 12 sessions (1-2 sessions a week), with each session lasting 60 minutes from May 8 to June 16, 2017. The control group, who did not participate in the five senses activities in the forest, participated in the Nuri Curriculum operated by the educational institution. Before and after the program, tests to measure daily stress in three different situations (encountering blame-aggression situation, experiencing anxiety-frustration, and losing self-respect) were conducted on young children and the data were analyzed using SPSS 21.0. As a result, daily stress of the young children decreased in all three situations with statistical significance. Through the five senses activities in the forest, young children could feel the nature by observing and exploring it in the forest, so which reduced their daily stress compared to the activities carried out in the classroom.

• Asian Pacific Journal of Cancer Prevention
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• 제15권13호
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• pp.5337-5341
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• 2014

Background: The standard therapy for stage I rectum cancer is surgical resection. Currently, there is no strong evidence to suggest that any type of adjuvant therapy is beneficial. The risks of local relapse and distant metastasis are higher in rectal tumors. Therefore, while there is no clearly defined absolute indication for adjuvant therapy in lymph node negative colon cancers, rectum tumors that are T3N0 and higher require adjuvant treatment. Due to the more aggressive nature of rectal cancers, we explored the clinical and pathologic factors that could predict the risk of relapse in Stage I (T1-T2) disease and whether there was any progression-free survival benefit to adjuvant therapy. Materials and Methods: This multicenter study was carried out by the Anatolian Society of Medical Oncology. A total of 178 patients with rectal cancers who underwent curative surgery between January 1994 and August 2012 in 13 centers were included in the study. Patient demographics, including survival data and tumor characteristics were obtained from medical charts. Results: The median age was 58 years (range 26-85 years). Most tumors were well or moderately differentiated. For adjuvant treatment, 13 patients (7.3%) received radiotherapy alone, 12 patients (6.7%) received chemotherapy alone and 15 patients (8.4%) were given chemoradiotherapy. Median follow up was 29 months (3-225 months). Some 42 patients (23.6%) had relapse during follow up; 30 with local recurrence (71.4%) whereas 12 (28.6%) were distant metastases. Among the patients, 5-year DFS was 64% and OS was 82%. Mucinous histology and receiving adjuvant therapy were found to have statistically insignificant correlations with relapse and survival. Conclusions: In our retrospective analysis, approximately one quarter of patients exhibited either local or systemic relapse. The rates of relapse were slightly higher in the patients who had no adjuvant therapy. There may thus be a role for adjuvant therapy in high-risk stage I rectal tumors.

• 융합정보논문지
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• 제10권1호
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• pp.219-234
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• 2020

한국은 고령화에 따라 지역사회를 중심으로 보건의료 전문직 여성이 지속해서 증가할 것으로 예상된다. 이에 본 연구는 지역사회 보건의료 전문직 여성의 직무 스트레스로 인한 고통 체험 현상의 본질을 파악하여 구조화하고, 이를 통해 보건의료 전문직 여성의 직무 수행을 지지하는 기초자료를 제공하고자 한다. Parse의 인간되어감 질적 연구의 수행을 위해 지역사회에 종사하는 보건의료 전문직 여성 9명을 선정하였다. 연구자는 너와 나의 관계 형성 이후 진솔한 대화를 통해 참여자의 고통 체험 현상을 녹음하였다. 참여자의 구술은 추출-종합, 발견적 해석 과정을 통해 인간되어감 이론의 구조로 전환하고, 개념적 해석을 통해 체험의 구조를 구체화하였다. 그 결과 보건의료 전문직 여성 참여자는 열악한 근무 여건으로 직무 스트레스를 경험하고, 직장과 가정의 역할 갈등으로 고통 받지만 변화에 대한 기대감으로 능력 및 소통 강화를 통해 현실을 극복하려 노력하는 과정이다. 본 연구의 결과로 볼 때 보건 의료 전문직 여성의 근무 여건 개선을 통해 이들이 안정적으로 근무할 수 있는 국가 차원의 복지 정책이 시행되어야 한다.

• Journal of Korean Neurosurgical Society
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• 제29권7호
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• pp.910-917
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• 2000

Introduction : The management of chordomas and chondrosarcomas in the skull base is difficult due to the critical location, locally aggressive nature, and high recurrence rate. The authors present the effectiveness of surgical removal and radiation therapy on survival and tumor recurrence. Material and Methods : Thirty cranial base chordomas and chondrosarcomas from 23 patients(14 patients with chordomas and 9 patients with chondrosarcomas) were operated in our institution between 1985 and 1998. There were 15 men and 8 women, with a mean age of 40.7 years. The largest diameter of tumors ranged from 15 to 70mm (mean 41.5). The extent of surgical removal was subtotal or total in a half(15 operations). In nineteen operations, tumors were removed by conventional approaches and skull base approaches were applied in 11 operations. Postoperative radiation therapy was performed in 16(70%) patients. The mean duration of follow up is 50 months(1- 156 months). Results : The 3- and 5-year survival rates(YSR) of overall patient are 75% and 67%, respectively. The analysis showed that 1) skull base approach to chordomas and chondrosarcomas showed a tendency to remove more portion of the tumors(p＝0.058) but leave more frequent incidence of new deficits(p＝0.047) : 2) larger tumor diameter af-fected the extent of removal(p＝0.028) : 3) the extent of removal seemed to be the determining factor for overall survival and recurrence-free survival(the 5-YSR and RFSR of subtotal or total removal group are 92% and 80% vs. 40% of partial removal or biopsy group) : 4) conventional radiation therapy improved patient survival(5-YSR of patients who received RT is 76% whereas 5-YSR of those who didn't receive RT is 43%) but failed to prolong long-term recurrence-free survival. Conclusion : The extent of removal and postoperative radiation therapy are determining factors of patients' survival in skull base chordomas and chondrosarcomas. However, none of these factors significantly influenced the survival in multivariate analysis. Aggressive surgical removal of more than subtotal resection combined with postoperative radiation therapy seems to be the choice of therapy in the management of these tumors.

• 대한골관절종양학회지
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• 제12권1호
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• pp.78-82
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• 2006

Kimura씨 병은 정확한 병인이 알려지지 않은 매우 드문 만성 염증성 질환으로 알려져 왔다. 주로 단독 또는 다발성으로 피하층에 결절 형태로 발생하며 대부분 양성인 경과를 취한다. 주로 경부에 주변 림파선 증식을 동반하여 발생한다. 조직학적으로 림프양 조직이 증식되어 있고, 호산구가 많은 염증 세포의 침윤과 모세 세정맥이 풍부한 병리 소견을 보인다. 치료방법으로는 스테로이드 치료, 방사선 치료 및 수술적 치료 등이 있다. 저자들은 상지에 발생한 2예의 Kimura씨 병을 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

• 대한한의학원전학회지
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• 제21권3호
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• pp.103-117
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• 2008

At first, we explained concepts of Oseong(五聲) in "Akhakgwebeom(樂學軌範)" and then compared them with O-eum(五音) in "Hwangjenaegyeong(黃帝內經)". In that progress we can have recognized the commonness and differences between two texts, and became familiar with ideas of sounds in minds of ancients. That ideas are concerned with true nature of human and cosmos. Based on that ideas, we could return to stasis of mutual understanding with each other, it means a condition of harmony. For that purpose we must understand detail meanings of O-eum(五音) and Oseong(五聲), and this analysis lead clinical music therapy to do an important thing as methodology of treating human body and minds. The ideas of O-eum(五音) in "Akhakgwebeom(樂學軌範)" are not exactly corresponded to vocalization of Hunminjeongeum(訓民正音) that is Korean characters, and Oseong(五聲) in "Hwangjenaegyeong(黃帝內經)". But this dissonancy is a problem of methodology, on the contrary, there are many common concepts and possibilities of application to practical uses between them.

• 대한골관절종양학회지
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• 제7권1호
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• pp.36-40
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• 2001

기무라씨병은 종괴를 형성하는 원인 불명의 흔치 않는 만성 염증성 질환으로서 동양인에서 자주 이환되며 특히 젊은 남자에서 호발된다. 호발 장소는 주로 두경부이며, 일차적으로 피하 조직과 진피에 발생된다. 비교적 양호한 경과를 보이며, 그 치료 방법으로는 수술적 절제술, 스테로이드 투여법 및 방사선 조사 등이 있다. 저자들은 우측 상완부에 발생한 무통성의 비교적 유동성이 있는 연부 조직 종양 1례에 대한 변연부 절제술을 시행하여 병리조직학적으로 기무라씨병으로 확진하였으며, 수술 후 15개월 추시 상 재발 소견은 없었다.

• The Journal of Korean Physical Therapy
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• 제27권1호
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• pp.30-37
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• 2015

Purpose: The purpose of this study was to develop a computer access assessment tool for persons with physical disabilities and to evaluate reliability and validity. Methods: We developed a computerized Computer access Assessment Program (CAP) through many kinds of literature review and tools analysis for evaluation of computer access, task analysis of fundamental input devices operation and expert review. The CAP data were obtained from 105 normal university students and 16 students with physical disabilities. The test items of CAP are composed of four timed mouse tasks, four timed keyboard tasks, and a timed scanning task. Thus, the software measures user performance in skills needed for computer interaction, such as keyboard and pointer use, navigating through menus, and scanning. To determine the validity of these measurements, we compared data on CAP reports to a Compass report. Compass software allows an evaluator for assessment of an individual's computer input skills. Results: Results of this study showed that the CAP had high internal consistency, reliability of test-retest, concurrent validity, and convergent validity. Conclusion: Therefore, the CAP is appropriate for evaluation and determination of computer access skill of persons with physical disabilities. It is possible to get clear quantitative data on performance when providing computer access services if you can use the CAP data. Using this quantitative evidence, insights can be gained into the specific nature of any difficulties experienced by persons with physical disabilities and find wise solutions.

• Journal of mucopolysaccharidosis and rare diseases
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• 제4권1호
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• pp.21-25
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• 2018

Fabry disease is a hereditary lysosomal storage disorder caused by the reduction or absence of lysosomal enzyme alpha-galactosidase A and the accumulation of glycosphingolipids, such as globotriaosylceramide (Gb3), in various organs, including the heart. The prevention of cardiac involvement in Fabry disease can only be achieved by enzyme replacement therapy (ERT), and the method of assessing the efficacy of ERT should be confirmed. Changes in the electrocardiogram, such as the shortening of PQ interval, prolongation of QTc and repolarization abnormalities as well as left ventricular hypertrophy in voltage criteria, can be used to identify Fabry disease patients; however, the usefulness of electrocardiograms for evaluating the efficacy of ERT is limited. The assessment of left ventricular hypertrophy using echocardiography has been established to evaluate the efficacy of ERT during long-term period. A new technique involving speckled tracking method might be useful for detecting early cardiac dysfunction and identifying the effect of ERT for a relatively short period. The estimation of left ventricular hypertrophy using cardiac magnetic resonance (CMR) is also useful for assessing the efficacy of ERT. Identifying late gadolinium enhancement in CMR may affect the effectiveness of ERT, and the new technique of T1 mapping might be useful for monitoring the accumulation of Gb3 during ERT. Histopathology in cardiac biopsy specimens is another potentially useful method for identifying the accumulation of GB3; however, the use of histopathology to evaluate of the efficacy of ERT is limited because of the invasive nature of an endomyocardial biopsy.

• 턱관절균형의학회지
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• 제4권1호
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• pp.21-26
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• 2014

본 증례에서는 원인 불명의 만성 재발성 악관절 탈구 및 개구 장애에 대해 CBA, TBA를 비롯한 FCST의 구조적 치료를 통해서도 유의한 치료변화가 나타남을 관찰하였다.