• BMB Reports
• /
• v.45 no.2
• /
• pp.71-78
• /
• 2012

Bdellovibrio bacteriovorus is a predatory bacterium which attacks and consumes other bacterial strains, including the well known pathogens E. coli O157 : H7, Salmonella typhimurium and Helicobacter pylori. This remarkable activity has been the focus of research for nearly five decades, with exciting practical applications to medical, agriculture and farming practices recently being published. This article reviews many of the exciting steps research into this bacterium, and similar bacteria, has taken, focusing primarily on their use as both an antibiotic to remove harmful and pathogenic bacteria and as a probiotic to help curb and control the bacterial populations within the intestinal tract. Owing to the unique and dual nature of this bacterium, this review proposes the use of "amphibiotic" to describe these bacteria and their activities.

• International Journal of Computer Science & Network Security
• /
• v.24 no.6
• /
• pp.17-22
• /
• 2024

Software cost and schedule estimation is usually based on the estimated size of the software. Advanced estimation techniques also make use of the diverse factors viz, nature of the project, staff skills available, time constraints, performance constraints, technology required and so on. Usually, estimation is based on an estimation model prepared with the help of experienced project managers. Estimation of software cost is predominantly a crucial activity as it incurs huge economic and strategic investment. However accurate estimation still remains a challenge as the algorithmic models used for Software Project planning and Estimation doesn't address the true dynamic nature of Software Development. This paper presents an efficient approach using the contemporary Constructive Cost Model (COCOMO) augmented with the desirable feature of fuzzy logic to address the uncertainty and flexibility associated with the cost drivers (Effort Multiplier Factor). The approach has been validated and interpreted by project experts and shows convincing results as compared to simple algorithmic models.

• Proceedings of the Korean Society for Technology of Plasticity Conference
• /
• 2004.10a
• /
• pp.44-47
• /
• 2004

Although bulk metallic glasses have many outstanding aspects in their chemical, mechanical or functional properties, some critical problems still hinder their wide application. The most important one is the brittle nature of them, which is the serious problem to structural application. So, to use viscous flow is now the only competent way to form bulk metallic glass. In this study, we investigated the basic nature of viscous flow of Zr-base bulk metallic glass, vitrelloy 1, in terms of process variables. The results were used to design the thermo-mechanical process composed of heating, holding, pressing, and cooling, which have unique influence on the glass transition and crystallization behavior. We adopted small load scale and dies with nano/micro patterns on them. The results were evaluated using several analytical methods.

• Journal of The Korean Association For Science Education
• /
• v.17 no.4
• /
• pp.359-371
• /
• 1997

The purpose of this investigation was to examine and compare pre-service and in-service secondary tearchers' beliefs about STS, particulary beliefs about the nature of science and technology and their interaction within society. For this study, a belief was defined as something that people believe and accept as true. Instrument used in this investigation was empirically developed multiple-choice instrument entitled the Tearchers' Belief about Science - Technology - Society(TBA-STS) by Peter A. Rubba and William L. Harkness. The result of survey showed that large percentages of the preservice and in-service secondary science teachers in the two samples held misconception about the nature of science and technology and their interactions within society. And there was no apparent difference between the samples on their beliefs about STS interactions.

• Journal of the Korean Chemical Society
• /
• v.68 no.2
• /
• pp.107-116
• /
• 2024

The purpose of this study is to analyze changes in pre-service chemistry teachers' cognition of the nature of model in the evaluation and modification process of model using technology. Changes in cognition of the nature of model were analyzed focusing on the 'Abstraction' and 'Simplification' of the 'Representational aspect', 'Interpretation', 'Reasoning', 'Explanation' and 'Quantification' of the 'Explanatory aspect' that were deemed insufficient for pre-chemistry teachers in previous study. For this purpose, 19 third-year pre-service chemistry teachers at a teacher's college in Chungcheongbuk-do were asked to evaluate the model related to Boyle's law developed using technology, revise the model based on the evaluation results, and make a final evaluation. As a result of the study, it was confirmed that pre-service chemistry teachers' cognition of 'Simplification' of the 'Representational aspect' and 'Interpretation', 'Explanation', and 'Quantification' of the 'Explanatory aspect' changed positively through the evaluation and modification process of the model. Therefore, it was found that the evaluation and modification process of the model plays a key role in changing the cognition of the nature of model. However, there was little change in cognition of 'Abstraction' of the 'Representational aspect' and 'Reasoning' of the 'Explanatory aspect'. The cognition of these factors can be seen as more difficult to change than the cognition of other factors. To solve this problem, more sophisticated educational design for pre-service chemistry teachers is needed.

• Journal of the Society of Cosmetic Scientists of Korea
• /
• v.33 no.3
• /
• pp.165-173
• /
• 2007

In the previous study, we reported the antioxidative and cellular protective effects of Jeju native plant extracts. In this study, we investigated the anti-oxidative, anti-wrinkle and whitening effects of new 37 plant extracts collected from self-growing plants in Jeju island. Their anti-oxidant activities were measured by the 1,1-diphenyl-2-picrylhydrazyl(DPPH) radical scavenging assay and reactive oxygen species(ROS) scavenging assay in $Fe^{3+}-EDTA/H_2O_2$ system. The cytoprotective properties of 37 plant extracts were assessed in the rose-bengal sensitized photohemolysis of human erythrocytes. The inhibitory effect of 37 plant extracts on tyrosinase were investigated to assess their whitening efficacy. Finally, their anti-elastase activities were measured to predict the anti-wrinkle efficacy in the human skin. The results showed that the extracts of Myrica rubra stem bark and Securinega suffruticosa have the free radical scavenging activity($FSC_{50}:\;5,\;8{\mu}g/mL$, respectively), and the extracts of Quercus acutissima leaf and Securinega suffruticosa stem bark have the prominent ROS scavenging activity($OSC_{50}:\;0.009{\mu}g/mL$). Photohemolysis of erythrocytes in the presence of rose-bengal as a sensitizer was inhibited by the extracts of Securinega suffruticosa stem bark and Salix koreensis stem(${\tau}_{50}$, 895 min, 640 min at 50 ${\mu}g/mL$, respectively. Myrica rubra stem bark extract(77.8% at 200 ${\mu}g/mL$) and Salix koreensis stem extract(76.2% at 200 ${\mu}g/mL$) also have the inhibitory effect on tyrosinase and elastase activities, respectively. These results indicated that the stem park of Myrica rubra, Securinega suffruticosa, and Camellia japonica, the stem of Salix koreensis, and the leaf of Quercus aqutissima and Camellia japonica could have e benefitial effects when they are added as ingredients in cosmetics.

• Journal of the Korean Applied Science and Technology
• /
• v.26 no.2
• /
• pp.117-123
• /
• 2009

Caprylic/Capric triglyceride-in-water emulsions stabilized by Nikkol HCO-60 and HCO-10 were prepared using emulsion inversion point method at different HLB values. Emulsions with various droplet sizes were formed, and emulsion inversion point was detected by electrical conductivity. The change in emulsion droplet sizes and long term stability were monitored using laser scattering method and visual method. The droplet sizes and stability of emulsions were affected by HLB of surfactant. At emulsion inversion point, the water volume fraction increased as the HLB of surfactants decreased. According to our analysis, this resulted from a tendency of forming the W/O (water-in-oil) emulsion as the HLB of surfactants was decreased. The emulsion inversion point was clearly detected by the microscope and the electric conductivity meter. Nanometer-sized emulsion was obtained at the optimum HLB by using emulsion inversion point method. The main pattern of instability of emulsions in HLB 12 and 13 systems was Ostwald ripening. However, The patterns of instability of emulsions below 11 of HLB systems were Ostwald ripening and coalescence. All emulsions produced with surfactants in the range of HLB 8-13, creaming caused by density difference between water phase and oil phase.

• Journal of the Korean Applied Science and Technology
• /
• v.26 no.3
• /
• pp.269-278
• /
• 2009

In this study, the anti oxidative effects, inhibitory effects on elastase, and components of Securinega suffruticosa extracts were investigated. The free radical (1,1-diphenyl-2-picrylhydrazyl, DPPH) scavenging activities ($FSC_{50}$) and reactive oxygen species ROS) scavenging activities ($OSC_{50}$) of extract/fractions from Securinega suffruticosa were measured. The aglycone fraction ($9.04\;{\pm}\;0.51\;{\mu}g/mL$) and 50 % ethanol extract ($1.05\;{\pm}\;0.41\;{\mu}g/mL$) showed the most effective scavenging activities. The protective effects on the rose-bengal sensitized photohemolysis of human erythrocytes were investigated. The aglycone fraction exhibited the most prominent cellular protective effect (${\tau}_{50},\;102.77\;{\pm}\;5.37$ min at $10{\mu}g/mL$). The inhibitory effect of ethyl acetate fraction on tyrosinase were of examined ($210.0\;{\pm}\;1.02\;{\mu}g/mL$). The inhibitory effect of aglycone fraction on elastase were also investigated ($17.6\;{\pm}\;1.26\;{\mu}g/mL$). These results indicate that extract/fractions of Securinega suffruticosa can function as antioxidants in biological systems, particularly skin exposed to UV radiation by scavenging $^1O_2$ and other ROS, and protect cellular membranes against ROS. Securinega suffruticosa extract could be used as a new cosmeceutical ingredient for whitening and anti-wrinkle products.

• MALSORI
• /
• no.spc1
• /
• pp.24-32
• /
• 2002

• Journal of the Korean Society of Environmental Restoration Technology
• /
• v.9 no.4
• /
• pp.36-51
• /
• 2006

Although the demand and necessity for the facilities of nature environmental conservation and its utilization have been increased recently, the local governments has been experiencing difficulties to launch the facilities since there are no confirmed principles or guidelines for the direction of the facility and distinctions from the ordinary parks. In this regard, the aim of this paper is to provide the overall framework for establishing the facility by equipping checklists from planning to operational stage. The stages are disengaged into 5 steps of siting feasibility, planning, preliminary environmental assessment and environmental impact assessment, design, construction, and operation. This paper also include the recommendations to vitalize the existing facilities, of which expansion of educational program development; utilization of various manpower; provision of appropriate settings; strengthened monitoring; and increased public relations. Furthermore, it is suggested to consider the strengthened local characteristics, reviewing management plan at the stage of applying a new facility establishment to the concerned authority, fostering experts, and expansion of the facilities through restoration of environmentally damaged areas for a new facility.