• IMMUNE NETWORK
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• v.3 no.1
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• pp.8-15
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• 2003

Background: CD30 is a member of TNF receptor family and expressed on lymphocytes and other hematopoietic cells following activation as well as Hodgkin and Reed-Sternberg cells in Hodgkin's lymphoma. In this study, CD30-mediated regulation of cell adhesion molecule expression on normal activated mouse T cells was investigated. Methods: Mouse T cells were activated with anti-CD3 antibody for induction of CD30, which was cross-linked by immobilized anti-CD30 antibody. Results: High level of CD30 expression on T cells was observed on day 5, but only little on day 3 even under culture condition resulting in an identical T cell proliferation, indicating that CD30 expression requires a prolonged stimulation up to 5 days. Cross-linking of CD30 alone altered neither proliferation nor apoptosis of normal activated T cells. Instead, CD30 appeared to promote cell adherence to culture substrate, and considerably upregulated ICAM-1 and, to a lesser extent, ICAM-2 expression on activated T cells, whereas CD2 and CD18 (LFA-1) expression was not affected. None of cytokines known as main regulators of ICAM-1 expression on tissue cells (IL 4, $IFN{\gamma}$ and $IFN{\alpha}$) enhanced ICAM-1 expression in the absence of CD30 signals. On the other hand, addition of $NF-{\kappa}B$ inhibitor, PDTC (0.1 mM) completely abrogated the CD30-mediated upregulation of ICAM-1 expression, but not CD2 and ICAM-2 expression. Conclusion: This results support that CD30 upregulates ICAM-1 expression of T cell and such regulation is not mediated by higher cytokine production but $NF-{\kappa}B$ activation. Therefore, CD30 may play important roles in T-T or T-B cell interaction through regulation of ICAM-1, and -2 expression.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.20 no.1
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• pp.77-96
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• 2017

This study was carried out to clarify the climatic factors of the freezing injury for the judgement on the adaptation areas of evergreen broad-leaved trees. We surveyed and analyzed the climatic factors of the freezing injury to Machilus thunbergii Siebold & Zucc. on the streets with the analyzation of planting grounds, soil conditions and the surrounding buildings. This study showed that only the minimum air temperature factor out of the other climate elements, which were the annual precipitation; the average annual temperature; the average monthly temperature of january; the average monthly minimum temperature of January; the average temperature of the coldest month; the warmth index and the coldness index, was matched up with the previous theories and reports on the freezing damages on the evergreen broad leaved trees and Machilus thunbergii Siebold & Zucc. The freezing injury of Machilus thunbergii Siebold & Zucc was occurred when the mean minimum temperature of the coldest month(TMC) in winter season fell down below $-4.1^{\circ}C$ and the temperature fell down below $-9.2^{\circ}C$. The freezing damage on Machilus thunbergii Siebold & Zucc surrounded by high buildings were less than those surrounded by low buildings or at non buildings.

• Korean Institute of Interior Design Journal
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• no.38
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• pp.3-13
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• 2003

Now that 15 years have passed since its introduction to 4 year college in Korea and we have 51 majors in the field of Intoner design established at 47 universities as of 2003, we are in the position to seek the improvement of its educational qualify. With a view to provide data for the setup of proper educational purpose, it has classified their divisions(departments) according to their major names and belonged colleges of the universities and considered their geographical distributions, groupings of curriculum, their framing and features of a standard curriculum. 1)Divisions of the universities where the major of interior design belongs are divided into three categories of design division (design 8t arts, arts), home economics division (home economics, natural science) and architectural division. For the development of the major, universities to which circumstances permit are recommended to establish an independent college of interior design following the . cases in the US. 2) Geographical preponderance of interior design major on Seoul and Gyeongsang Province is desired to be improved. 3) Curriculum of interior design, which is classified into introduction, history of interior design, theory of interior design, design of interior space, digital technology, design elements of inner space, technology of interior design, behavior of environmental psychology, design management and other subjects, was made into a table by divisions. To sum up, curriculum of interior design concentrates on basic design theory throughout all divisions. In connection with the selection of division by high school-graduates or their parents, design division is recommended for those who desire to major in design elements and design management, home economics division for those who desire to major in space design and behavior of environmental psychology and architectural division for those who desire to major in Interior space design, interior design technology and regulations. 4) This research can contribute to the settlement of desirable curriculum for the interior design education, thus upgrading the education level of the major in Korea.

• Journal of the Korean Crystal Growth and Crystal Technology
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• v.23 no.5
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• pp.235-240
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• 2013

Pure-carbon materials such as graphite, graphene, carbon nanotubes, and diamond have very high thermal conductivities. The reported thermal conductivity of graphene is in the range 3000~5000W/m-K at room temperature. Here, we developed graphene/cu foam hybrid type heat spreader to obtain higher thermal conductivity than Cu foam. Hybrid materials were characterized using optical microscopy (OM), scanning electron microscopy (SEM) and thermal conductivity measurement system; LFA (Laser Flash Analysis @ LFA 447, NETZSCH). We suggest that excellent thermal properties of graphene/cu foam hybrid structures are beneficial for all proposed electrical applications and can lead to a thermal management application.

• Journal of the Korean Society of Clothing and Textiles
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• v.10 no.3
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• pp.37-48
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• 1986

The purpose of this study was to analyze 'the natural groupings' of subjects in order to classify highly similar somatotype for clothing construction. The sample for the study was drawn randomly out of senior high school boys in Seoul urban area. The sample size was 425 boys between age 16 and 18. Cluster analysis was more concerned with finding the hierarchical structure of subjects by three dimensional distance of stature. bust girth and sleeve length. The groups forming a partition can be subdivided into 5 and 6 sets by the hierarchical tree of the given subjects. Ward's Minimum Variance Method was applied after extraction of distance matrix by the Standardized Euclidean Distance. All of the above data was analyzed by the computer installed at Korea Advanced Institute of Science and Technology. The major findings, take for instance, of 16 age group can be summarized as follows. The results of cluster analysis of this study: 1. Cluster 1 (32 persons means $18.29\%$ of the total) is characterized with smaller bust girth than that of cluster 5, but stature and sleeve length of the cluster 1 are the largest group. 2. Cluster 2 (18 Persons means $10.29\%$ of the total) is characterized with the group of the smallest stature and sleeve length, but bust girth larger than that of cluster 3. 3. Cluster 3(35persons means $20\%$ of the total) is classified with the smallest group of all the stature, bust girth and sleeve length. 4. Cluster 4(60 persons means $34.29\%$ of the total) is grouped with the same value of sleeve length with the mean value of 16 age group, but the stature and bust girth is smaller than the mean value of this age group. 5. Cluster 5(30 persons means $17.14\%$ of the total) is characterized with smaller stature than that of cluster 1, and with larger bust girth than that of cluster 1, but with the same value of the sleeve length with the mean value of the 16 age group.

• Ocean and Polar Research
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• v.28 no.3
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• pp.339-352
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• 2006

Seasonal and tidal variations of density stratification in the Saemangeum waters are investigated based on synoptic CTD observations between July 2003 and September 2005. CTD data used in this study are those obtained after closing the dike No. 4 and before closing the two final gaps, the Sinsi and the Garyeok, on the Saemangeum tidal harrier. A total of 19 field campaigns comprehend a wide temporal spectrum, that is, few seasons, spring and neap tides, and high and low waters. In addition, ADCPs were anchored and CTDs were cast at three stations for 25 h in July 2005. Water columns are vertically homogeneous in autumn and winter. The vertical homogeneity persists in spring but with an occasional weak stratification in i:he northern part of the Gogunsan Islands. Increased reshwater runoff tends to stabilize the water columns and strong density stratification is established in summer. The mean potential energy anomaly (PEA) in summer used as a stratification parameter is the largest $(27.7\;J\;m^{-3})$ in the northern part of the Gogunsan Islands where the Geum River discharge dominates, the smallest $(16.9\;J\;m^{-3})$ is in the inner area of the barrier, in between the two $(21.6\;J\;m^{-3})$ in the southern part of the Gogunsan Islands. Whereas the stratification is generally strengthened in summer, strong winds or large tidal currents over the shallow depths frequently destratify the water column near the mouth of river runoff inside the tidal barrier. Periodic stratification, the development of stratification on the ebb and its breakdown on the flood, occurs in the mid-area inside the barrier induced by the tidal straining, which can also be found in the results of 25 h observation.

• Korean Journal of Veterinary Research
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• v.39 no.1
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• pp.111-117
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• 1999

A nation wide sero-epidemiological survey of porcine reproductive and respiratory syndrome(PRRS) was carried out to analyze the current status of the PRRS virus infections in the field using the indirect immunofluorescent antibody assay(IFA) with the field isolate PL96-1. Since the first report of the antibody detection to PRRSV in 1993, the prevalence of seropositive pigs has increased dramatically and the data indicate that over 21% of the pigs and around 60% of the farms showed seropositives to the PRRS virus. A slightly higher positive rate was recognized in breeders than fattenings and it might be due to the higher age at the time of testings. No significant regional differences were detected in the sero-epidemiological survey. Higher sero-positive rate in growers indicates that PRRSV infection in the field was common after weaning(around 40 days). However, the number of seropositive pigs were declined in fattening pigs. Sows showed around 26% of sero-positive rate that there is a higher chance of continuous virus circulation in the infected farms. Low rate of sero-positivity in boars(9.8%) implies that there is high demand in proper control measures to prevent virus spreading through breeding procedures such as natural or artificial insemination. Therefore it was concluded that PRRSV infection in domestic swine herds is endemic and the positive rate and economic loses will be increased by spontaneous infections in naive farms.

• Journal of The Korean Society of Agricultural Engineers
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• v.62 no.5
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• pp.15-26
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• 2020

There are fifteen non-point pollution management areas in Korea and three of them (Doam lake, Daegi district and Golji-cheon) are located in the upstream of the Namhan river watershed. Many efforts to reduce non-point sources (NPS) pollution have been conducted, however, water quality pollution in the watershed is still serious. To solve these problems, it is a priority to grasp water quality using statistical techniques. In this study, a trend analysis was conducted to evaluate the effect of NPS management in the watershed. The long-term trends from 1996 to 2018 of water quality properties were analyzed using data collected from the water environment information system. Seventeen monitoring stations were selected along the main stream in Namhan river basin. Monthly water quality properties (BOD, COD, TN, TP, TN/TP ratio, Conductivity, SS and Chlorophyll-a) were collected and analyzed by Mann-Kendall test and LOWESS. The results showed that the Conductivity tended to increase in all regions and was the highest level in Jijangcheon. Organic pollution such as BOD and COD tended to increase in the Jungseon area. SS did not show a large tendency, but it showed high concentration in the Doam watershed. In all regions, 40% of water quality properties showed a tendency to 'UP', 15% of water quality properties tended to 'DOWN', and 46% indicated no tendency. In order to determine the cause of this, additional research and measures for improvement are necessary. This study will be used for the establishment of water quality policy in the future.

• Membrane and Water Treatment
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• v.11 no.5
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• pp.323-331
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• 2020

With the increasing demand on reverse osmosis (RO) membranes for water purification worldwide, the number of disposed membrane elements is expected to increase accordingly. Thus, recycling and reuse of end-of-life RO membranes should be a global environmental action. In this work, we aim to reuse the spent RO membrane for nanofiltration (NF) and ultrafiltration (UF) process by subjecting the spent membrane to solvent and oxidizing solution treatment, respectively. Our results showed that solvent-treated RO membrane could perform as good as commercial NF membrane by achieving similar separation efficiencies, but with reduced water permeability due to membrane surface fouling. By degrading the polyamide layer of RO membrane, the transformed membrane could achieve high water permeability (85.6 L/㎡.h.bar) and excellent rejection against macromolecules (at least 87.4%), suggesting its reuse potential as UF membrane. More importantly, our findings showed that in-situ transformation on the spent RO membrane using solvent and oxidizing solution could be safely conducted as the properties of the entire spiral wound element did not show significant changes upon prolonged exposure of these two solutions. Our findings are important to open up new possibilities for the discarded RO membranes for reuse in NF and UF process, prolonging the lifespan of spent membranes and promoting the sustainability of the membrane process.

• Toxicological Research
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• v.33 no.4
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• pp.305-313
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• 2017

Accumulating epidemiological evidence indicates that exposure to fine air pollution particles (APPs) is associated with a variety of adverse health effects. However, the exact physiochemical properties and biological toxicities of fine APPs are still not well characterized. We collected four types of fine particle (FP) (diesel exhaust particles [DEPs], natural organic combustion [NOC] ash, synthetic organic combustion [SOC] ash, and yellow sand dust [YSD]) and investigated their physicochemical properties and in vitro biological toxicity. DEPs were almost entirely composed of ultrafine particles (UFPs), while the NOC, SOC, and YSD particles were a mixture of UFPs and FPs. The main elements in the DEPs, NOC ash, SOC ash, and YSD were black carbon, silicon, black carbon, and silicon, respectively. DEPs exhibited dose-dependent mutagenicity even at a low dose in Salmonella typhimurium TA 98 and 100 strains in an Ames test for genotoxicity. However, NOC, SOC, and YSD particles did not show any mutagenicity at high doses. The neutral red uptake assay to test cell viability revealed that DEPs showed dose-dependent potent cytotoxicity even at a low concentration. The toxicity of DEPs was relatively higher than that of NOC, SOC, and YSD particles. Therefore, these results indicate that among the four FPs, DEPs showed the highest in vitro biological toxicity. Additional comprehensive research studies such as chemical analysis and in vivo acute and chronic inhalation toxicity tests are necessary to determine and clarify the effects of this air contaminant on human health.