• Journal of Microbiology and Biotechnology
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• v.29 no.2
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• pp.230-234
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• 2019

Currently, the genetic modification of Aspergillus oryzae is mainly dependent on protoplast-mediated transformation (PMT). In this study, we established a dual selection marker system in an industrial A. oryzae 3.042 strain by using Agrobacterium tumefaciens-mediated transformation (ATMT). We first constructed a uridine/uracil auxotrophic A. oryzae 3.042 strain and a pyrithiamine (PT)-resistance binary vector. Then, we established the ATMT system by using uridine/uracil auxotrophy and PT-resistance genes as selection markers. Finally, a dual selection marker ATMT system was developed. This study demonstrates a useful dual selection marker transformation system for genetic manipulations of A. oryzae 3.042.

• Asian Journal of Innovation and Policy
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• v.1 no.1
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• pp.92-115
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• 2012

The problem Japanese universities face is exactly the same as that of German universities: no international recognition in world rankings of universities despite their high levels of postwar economic and technological developments. This was indeed one reason why world-class Japanese firms, such as Toyota and Sony, have avoided working closely with Japanese universities for R&D partnership and new technology commercialization. To resolve this problem, the Japanese government has continuously implemented aggressive policies of the internationalization, privatization, liberalization, and privatization of universities since the onset of the economic recession in 1989 in order to revitalize the Japanese economy through radical innovation projects between universities and firms. National projects of developing medical robots for Japan's ageing society are some of the ambitious examples that emphasize feed-forward learning in innovation. However, this paper argues that none of these programs of fostering university-firm alliances toward feed-forward learning has been successful in promoting the world ranking of Japanese universities, although they showed potentials of reinforcing their conventional strength of introducing $kaizen$ through feedback learning of tacit knowledge. It is therefore argued in this paper that Japanese universities and firms should focus on feedback learning as a way to motivate firm-university R&D alliances.

• IE interfaces
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• v.20 no.3
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• pp.363-375
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• 2007

Under the fast technology changes and budget constraints, the organizations related to national defense face increased demands to develop innovative strategy and methodology to maximize performance with drastically reduced cost. In this context, the management of innovation and change in the defense acquisition area is vital to the Ministry of National Defense, related organizations and industries. In this paper, we discuss three comprehensive innovation strategies and methodologies for the defense acquisition area preparing for next-generation warfare; EVMS (earned value management system), PBL (performance based logistics) and SBA (simulation based acquisition). These collaborating innovative efforts enable us to tackle defense challenges for government and industries with a flexible and optimistic approach that maximizes productivity and performance with minimum cost.

• World Technopolis Review
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• v.1 no.1
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• pp.27-41
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• 2012

The science and technology park movement has been developing for over 60 years. The first developments simply relied on the co-location of tenant companies and the park's host to encourage technology transfer. This is in contrast with their modern counter parts which offer a range of active links between tenant companies and host organisations as well as a raft of business development services to support technology commercialisation. Many of these sites have also become important centres in regional innovation plans. In these cases they are supported by a range of local, regional and national policies that are aimed at establishing a business, technology and social environment which support innovation. The paper examines both the business development programmes developed by science and technology parks to support technology commercialisation and the macro conditions that are now being developed to support innovation.

• Proceedings of the Technology Innovation Conference
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• 2003.02a
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• pp.155-172
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• 2003

Government Research Institutes(GRI), together with universities and private research labs, constitute the core of the Korea's national innovation system, The aim of this paper is to analyze the current system of GRIs and the National Research Councils(RC) in Korea, and suggest some policy recommendations conducive to achieving a world class competitive research system. To identify the problems and policy issues, we have conducted interviews (with executives staffs of RCs, GRIs and government ministries) and questionnaire surveys. For benchmarking purposes, we have visited 9 public research institutes in the USA, UK, Germany, and France. From the analysis of the problems revealed from the interviews and questionnaires, 6 policy variables are identified: three of them, which we call systemware variables, are governance structure, resources allocation system, and management control system; and the other three, which we call humanware variables, are visions and strategic goals, leadership, and research manpower, respectively. We have found that 1;he current GRI/RC systems are inefficient mainly due to the rigid and bureaucratic governance structure and inconsistent resource (i.e., government budgets) allocation systems. We reject the idea of replacing the current RC system with such radical alternatives as 're-governmentization'or 'privatization'. Instead we recommend that the government introduce a better system of governance and national budget allocations, which in turn would help induce a better management control systems, clear research visions and goals, strong leadership on the part of the RC chairman, and more creative and motivated researchers. These recommendations may provide opportunities and rooms for chairmen of RCs and presidents of GRIs to exercise more positive leadership in terms of fitting the visions and goal of GRIs to the national R&D strategy and creating a rational management control system as well as motivating researchers in GRIs to be more creative and productive.

• Journal of the Ergonomics Society of Korea
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• v.36 no.5
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• pp.395-409
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• 2017

Objective: The purpose of this study was to optimize the number and positions of foot pressure sensors using the reliability analysis of the center of pressure (COP) in smart shoes. Background: Foot pressure can be different according to foot region, and it is important which region of the foot pressure needs to be measured. Method: Thirty adults (age: $20.5{\pm}1.8years$, body weight: $71.4{\pm}6.5kg$, height: $1.76{\pm}0.04m$) participated in this study. The foot pressure data were collected using the insole of Pedar-X system (Novel GmbH, USA) with a sampling frequency of 100Hz during 1.3m/s speed walking on the treadmill (Instrumented treadmill, Bertec, USA). The intraclass correlation coefficients (ICC) were calculated between the COP positions using 4, 5, 6, 7, 8, and 99 sensors, while one-way repeated measure ANOVA was performed between the standard deviation (SD) of the COP positions. Results: The medio-lateral (M/L) COP position using 99 sensors was positively correlated with the M/L COP positions using 6, 7, and 8 sensors; however, it was not correlated with the M/L COP positions using 4 and 5 sensors during landing phase (1~4%) (p<.05). The antero-posterior (A/P) COP position using 99 sensors was positively correlated with the A/P COP positions using 4, 5, 6, 7, and 8 sensors (p<.05). The SD of the COP position using 99 sensors was smaller than the SD of the M/L COP positions using 4, 5, 6, 7, and 8 sensors (p<.05). Conclusion: Based on our findings, it is desirable to arrange at least 6 sensors in smart shoes. Application: The study of optimizing the number and positions of foot pressure sensors would contribute to developing more effective smart shoes using foot pressure technology.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.2 no.3
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• pp.103-122
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• 2007

Innovation clusters developed or evolved around a specific region IS the key element of national innovation system and determine national competitiveness. Recognizing the importance of innovation clusters, Korean government has made "Daedeok Special R&D Zone" in 2005. This paper examines the success factors of famous Cluster in advanced countries and China, and proposes the strategy for regional development in Daejeon through boosting Daedeok Innovation Cluster. Although 30.5% of government R&D investment is being concentrated in Daedeok along with 10% of the country's doctorate degree holders, it is lack of increasing revenue by linking corporate R&D with a creative and challenging entrepreneur spirit. The core of the innovation cluster is the integration and mutual networking of the main participants. This paper suggests strategies for developing as a world class innovation cluster, global networking and clustering, venture ecosystem formation, commercialization the knowledge by interacting with market. It also explains the necessity of regional integration for cluster to cluster linkages in the East Asia Region.

• Journal of Digital Policy
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• v.1 no.2
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• pp.41-45
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• 2022

In this study, we look at the current address of industrial complexes and the government's support policies for industrial complexes so far, examine the problems and improvements of industrial complexes in the era of great transformation, and then suggest how to innovate industrial complexes, and suggest the plans and tasks. want to report. To summarize the conclusion, in order to enhance the competitiveness and innovation of industrial complexes, which are the main axis of the national economy, a governance system in which the government, regional innovation organizations, and businesses cooperate must be established to transform industrial complexes suitable for the transition period and foster excellent industrial complexes. It is urgent to actively support the policy and budget input of each government department.

• Journal of Korea Technology Innovation Society
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• v.22 no.2
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• pp.207-219
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• 2019

The international trends in activities of government R&D performance measurement is evolving into evidence-based approach to support the verification of objective policy implementation. The European Commission has been implementing KETs (Key Enabling Technologies) policy that incubates nanotech based emerging technologies to support the fourth industrial revolution/revitalization of high-tech manufacturing, and resulting innovations are quantified by KETs Observatory project. The European Commission also built Innovation Radar system that monitors potentially innovative projects within FP7 and Horizon2020 by data analysis. The United States is also upgrading its Federal RePORTER system to quantitatively monitor federal R&D investments with outcomes (including nanotechnology). In the field of Korean nanotechnology, basic statistical data by analyzing NTIS (National Science & Technology Information Service) information is applied in policy field. Developing innovation measurement methodology beyond basic statistical analysis is an international policy issue, and a long-term R&D investment area of a government. The objective of this model study is to quantify the innovation potential of nano R&D investments conducted by Korea government, using input-output based efficiency measurement model and NTIS (National Science & Technology Information Service) that is comprehensive data portal for national R&D investments/outcomes including nanotechnology.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.13 no.1
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• pp.73-87
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• 2018

Creativity, entrepreneurship, and technological innovation orientation are key factors for technological innovation. The main driver of technological innovation in the enterprise is the executives of the firm. According to the Upper Echelons Theory of D.C. Hambrick(2007), the creativity of the managerial individual will be put into various aspects within the organization's innovation system. The organizational innovation system is positively influenced by the creativity of the executives, and is achieved by manifesting innovation orientation and technological innovation orientation with innovative performances. The purpose of this study is to investigate using Structural Equation Modeling(SEM), whether individual creativity of executives of 132 companies with research organizations among domestic semiconductor companies in Korea influences innovation performance of firms through entrepreneurship orientation and technology innovation orientation. We applied the personal creativity level measurement index, the entrepreneurial orientation measurement factor, and the technology innovation orientation measurement factor identified in the previous research literature. The results of the Structural Equation Modeling analysis show that the creativity of executives have a positive (+) relationship with the innovation performance of firms when they are only mediated by technological innovation orientation, and entrepreneurial orientation. On the other hand, the results of the SEM shows the direct effects between the creativity of executives and innovation performance are not statistically valid. As a result, the individual creativity of executives who lead the innovation of the firm, entrepreneurial orientation, and technological innovation orientation of the researcher organization are very important factors and an inseparable relationship for the successful innovation of the firms.