• 제목/요약/키워드: name of the department

검색결과 1,359건 처리시간 0.03초

Immunohistochemical Changes of Apoptotic Control Genes by Chronic Inhibition of Nitric Oxide in Rats

  • Bae, Hyung-Joon
    • 대한의생명과학회지
    • /
    • 제18권4호
    • /
    • pp.420-427
    • /
    • 2012
  • Sprague-Dawley (SD) rats were orally administered with NG-nitro-L-arginine methyl ester (L-NAME), which inhibits or blocks the production of nitric oxide from L-arginine in vascular endothelial cells and vessel tissue. We examined the effects of nitric oxide on some physiological changes such as blood pressure and heart rate, and confirms the apoptosis induced by the suppressed nitric oxide activity in the kidney. This study was performed to investigate correlation between the activities of nitric oxide and apoptosis by immunohistochemical changes of apoptotic control proteins with regulated chronic inhibition of nitric oxide. In the kidney from L-NAME-treated group, immunohistochemical reaction to the antigens of apoptosis inhibiting proteins such as bcl-2 and bcl-xL, exhibited a time-dependent reduction. The expression of apoptosis-inhibiting proteins such as bax and p53 increased expression in proportion to the duration of treatment. The most sensitive apoptosis regulating proteins to L-NAME were p53 in stimulation and bcl-2 in inhibition, respectively.

A Central Pressor Response to Endogenous Nitric Oxide Synthesis Inhibition in Anesthetized Rats

  • Moon, Sung-Ho;Yang, Min-Joon;Oh, Seung-Ho;Kim, Mi-Won;Yoo, Kwang-Jay;Lee, Jong-Eun;Jun, Jae-Yeoul;Yeum, Cheol-Ho;Yoon, Pyung-Jin
    • The Korean Journal of Physiology
    • /
    • 제28권2호
    • /
    • pp.197-202
    • /
    • 1994
  • The present study was aimed to determine if endogenous L-arginine-nitric oxide (NO) pathway has central, rather than peripheral, mechanisms in blood pressure regulation. Arterial blood pressure and heart rate responses to acute inhibition of the t-arginine-NO pathway were examined in rats anesthetized with thiopental (50 mg/kg, IP). An intracerebroventricular (ICV) cannula was placed in the left lateral ventricle. The right femoral artery was cannulated to measure arterial blood pressure and the vein to serve as an infusion route. $N^G-nitro-L-arginine$ methyl ester (L-NAME) was infused either intracerebroventricularly or intravenously. ICV infusion $(1.25\;{\mu}L/min)$ of L-NAME $(20\;or\;100\;{\mu}g/kg)$ per minute for 60 min) increased the mean arterial pressure and heart rate. Plasma renin concentrations(PRC) were significantly lower in L-NAME-infused group than in the control. L-Arginine $(60\;{\mu}g/min,\;ICV)$ prevented the pressor response to ICV L-NAME. The pressor response was not affected by simultaneous intravenous infusion of saralasin, but was abolished by hexamethonium treatment. Intravenous infusion $(40\;{\mu}L/min,\;10{\sim}100\;{\mu}g/kg\;per\;minute\;for\;60\;min)$ also increased blood pressure, while it decreased heart rate. These results indicate that endogenous L-arginine-NO pathway has separate central and peripheral mechanisms in regulating the cardiovascular function. The central effect may not be mediated via activation of renin-angiotensin system, but via, at least in part, activation of the sympathetic outflow.

  • PDF

국가도메인 네임 등록 수에 영향을 미치는 요인에 관한 국제 비교 (International Benchmarking on Factors Affecting the Number of Country Domain Name)

  • 김소라;전효정;김태성
    • 한국통신학회논문지
    • /
    • 제40권12호
    • /
    • pp.2434-2442
    • /
    • 2015
  • 사물인터넷(IoT) 시대가 도래하면서 각 개체를 식별하는 것이 중요해지고 있다. 도메인 네임, IP주소, OID 등의 인터넷주소자원이 식별자로서의 역할을 하게 될 것으로 기대되며, 그 수요 또한 증가할 것으로 예상되고 있다. 이에 따라 인터넷주소자원을 확보하는 것이 중요해지고 있으며, 인터넷주소자원 시장이 발달함에 따라 현재 시점에서 인터넷주소자원이 산업으로 발전할 가능성이 있는지 가늠해볼 필요가 있다. 이를 위해 본 연구에서는 국가 도메인 네임에 대하여 OECD 가입국 중 18개 국가를 대상으로 국가도메인 네임 등록 수에 영향을 미치는 요인을 선정하고 회귀분석을 실시한다.

사용자 수술명과 수술분류 code (ICD-9-CM) 일치율 향상에 관한 연구 (수술실 OCS program 사용 활성화를 통하여) (Study of matching user operation name and operation classification code (ICD-9-CM) (Through OCS program use facilitation at operating room))

  • 최향하;김미영;김도진;유지원;장정화;박수정;박재성
    • 한국의료질향상학회지
    • /
    • 제12권1호
    • /
    • pp.104-112
    • /
    • 2006
  • Background : The necessity of unify and standardize codes used at hospital has been emphasized since OCS (Order Communicating System) was adopted. Therefore, the purpose of this study were to standardize operation code by continuous training of the ICD-9-CM code that is used as standard code in OCS program at operating room. Method : In 400 operation data, operation code entered in OCS program at operating room was compared to operation name recorded in medical record. In addition, a matching rate between input data of operation code by medical record department and computing input data of operation code in 3,710 cases was compared for each department. User operation name and operation code were matched and major diagnosis by operation department and operation name were also matched. Results : User operation name was reflected in operation classification code in detail, and operation code entered on user was registered. Input rate and matching rate of operation code were gradually improved after improvement activity. In particular, a matching rate was high at ophthalmology where operation name is segmented. Plastic surgery and orthopedics with a lot of emergency operation and comprehensive operation name show low input rates. Conclusions : As the medical field makes progress in computerlization, awareness of information exchange and sharing becomes higher. Among codes to classified medical institution, codes related to surgical operation are all different by user of hospital and department. Computerlization and standardization is essential. And when efforts of standardization continue in alliance with individual hospital and institution, initiative of preparing medical policy data at a national level will be accelerated.

  • PDF

참고문헌 영문화 작업에 있어 영어번역의 전략 (Strategy for English Translations of Journal Reference)

  • 송호섭
    • Journal of Acupuncture Research
    • /
    • 제28권3호
    • /
    • pp.121-129
    • /
    • 2011
  • Objectives : This study was to propose how to translate journal references into english for enhancing citation index of the journals published in the Korean Oriental Medical Society. Methods : Journal reference is mainly composed of author name, title or book name, journal name such as Index Medicus or publisher name, etc. In order to find the appropriate equivalents to the above major constituents, head words extracted from all the references of Journal of Korean Oriental Medical Society published in 2002 to 2009. A plan for English translation of the journal reference was formulated and the glossary was prepared. Plan for English translation of the journal reference : 1. Author: Author name was represented as capitalized last name and two initials of first name and listed up to six. If there are more, the first three or six authors were listed with 'et al'. 2. Terminology of traditional Korean medicine: Standard korean traditional medical terminology was one of the current representative dictionary with as much as 6040 headwords, which was needed to be translated into English in order to provide substantial equivalents available for English translation of journal reference. Therefor 4361 english equivalents were to be newly adopted except for 1679 overlapped with them in WHO-IST. Source oriented translation and target oriented translation were allowed to be appropriately selected depending on the condition. In addition, principle of English translation of acupoint,medicinal Herbs, Herbal formula and classical works were proposed. 3. Basically the names of journals should be set in italics and abbreviated according to the List of journals indexed for medline (formerly Index Medicus) published by the National Library of Medicine. however, abbreviation of korean oriental medical journals were not yet established. Thus establishment of tentative korean index medicus should be considered. Conclusions : For the enhancement of journal citation index of korean traditional medical journals, it was suggested that english translation of journal reference should be one of the alternatives enhancing citation rate.

토착지명, 지리적 실체, 그리고 인식의 문제 -동해/일본해 표기 사례- (Endonym, Geographical Feature and Perception: The Case of the Name East Sea/Sea of Japan)

  • 주성재
    • 대한지리학회지
    • /
    • 제44권5호
    • /
    • pp.661-674
    • /
    • 2009
  • 최근 유엔지명전문가회의에서는 두 개 이상의 국가에 걸치거나 국경을 초월하여 존재하는 지리적 실체가 갖는 이름이 어떤 지위를 가질 것인가에 대하여 활발한 토론이 진행되었다. 두 개의 상반된 견해가 제시되었는데, 하나는 어떤 실체가 위치한 곳에서 사용되는 언어로 표기된 지명은 그 경계 내에서만 토착지명이라는 관점이며, 다른 하나는 어떤 언어로 표기된 지명은 전체에 대하여 토착지명이라는 관점이다. 전자는 지리적 실체가 나뉠 수 있음을 전제로 한다는 점에서 부분적 관점, 후자는 지리적 실체를 나뉘지 않는 전체로 인식한다는 점에서 전체적 관점이라고 부를 수 있다. 부분적 관점에서는 적어도 한국의 영해에서는 '동해'라고 불러야 한다는 점, 전체적 관점에서는 바다 전체에 대해 '동해'는 토착지명이 된다는 점 등에서 볼 때, 어떤 관점에서도 '동해'지명은 존중되어야 한다. 이 논문은 지리적 실체를 나눌 수 있고 각 부분은 다른 형태의 지명을 가질 수 있다는 부분적 관점을 지지한다. 지리적 실체의 분리에 대해서는 지역 주민들이 자신의 것으로 인식하는 바다의 경계를 사용해야 한다. 영어로 표기된 East Sea는 토착지명 '동해'의 번역된 형태로 분류하는 방안이 제안된다.

중국 동북 3성의 이식지명에 관한 연구 I - 연변 조선족 자치주를 사례로 - (A Study on the Place Name of Migration in Three Northeast Provinces of China I : Case of the Yanbian Korean Autonomous Prefecture)

  • 김남신;김석주
    • 한국지역지리학회지
    • /
    • 제20권2호
    • /
    • pp.153-162
    • /
    • 2014
  • 본 연구는 연변조선족자치주 조선족 마을 지명을 분석하여 한반도에서 유래된 이식지명의 분포와 유형을 파악하고자 하였다. 연구결과 연변조선족자치주에 분포하는 2,015개 마을 중, 조선족 거주지역은 945개 마을로 분석되었 다. 조선족 거주지 지명을 분석한 결과 한반도에서 유래된 이식지명은 51개로 파악되었다. 중국의 시대적 변천에 따라 한반도 기원의 이식지명은 현재까지, 34개 지명이 소실되었고, 유지된 지명은 16개, 그리고 소실 후 다시 복원된 지명은 1개로 나타났다. 이식지명은 명명 방법에 따라 소지역 직접이식, 대지역 직접이식, 병합이식으로 나눌 수 있었다. 소지역 직접이식은 전북 정읍, 무주와 같이 기원지와 도착지 지명이 같은 경우, 대지역 직접이식은 강원도 사람들이 마을을 이루어 명명한 강원촌, 그리고 병합이식은 함경도 길주와 석성면 지명이 결합되어 길성촌으로 명명된 경우가 예가 된다. 본 연구결과는 민족의 이주과정 및 정체성 연구를 위한 기초 정보를 제공해 줄 수 있을 것으로 기대된다.

  • PDF

지명 데이터베이스 구축을 통한 웹지도화 방안 (An Web-based Mapping by Constructing Database of Geographical Names)

  • 김남신
    • 한국지역지리학회지
    • /
    • 제16권4호
    • /
    • pp.428-439
    • /
    • 2010
  • 지명은 인간의 지역인식을 반영하기 때문에 지명지도는 지역이해를 위한 정보를 제공해 줄 수 있다. 본 연구는 지명데이터베이스 구축을 통한 웹기반 지도를 제작하고자 하였다. 주요 연구내용은 웹사이트 상에서 지명분류 방법, 데이터베이스 구축 방법 그리고 지명지도화 방법에 관한 연구를 수행하였다. 지명은 분류기준에 따라 자연지리, 문화역사지리, 경제지리, 기타의 4개 영역으로 나누었으며, 다시 18 가지 세부영역으로 분류하였다. 지명은 지형도상의 지명과 지역에만 알려진 소지명을 수집하여 입력할 수 있도록 하였다. 데이터베이스 항목은 주소, 좌표, 지명(한자, 한글), 지명분류, 설명, 사진 자료로 구성하였다. 지명지도는 지역의 지리정보와 함께 표현될 수 있게 하였다. 연구결과는 지명의 지리적 분포는 물론 지역해석을 위한 정보를 제공해 줄 수 있을 것으로 기대된다.

  • PDF

Significance of "Pre-Study Post-Designation" Strategy in Natural Monument Designation System: With Special Reference to Geologic Heritage

  • Kong, Dal-Yong;Lee, Seong-Joo
    • 한국지구과학회지
    • /
    • 제35권5호
    • /
    • pp.324-332
    • /
    • 2014
  • Many problems in naming natural monuments have been repeatedly argued by many researchers, and four different types of naming problems were identified: 1) name of unknown nationality (natural monument no. 82 and 108), 2) morphological name rather than scientific name (natural monument no. 180, 295, and 409), 3) name of fable character (local cultural property of Changnyeonggun), and 4) scientifically wrong name (natural monument no. 413). Among them, two cases (case 3 and 4) using wrong names are found in natural monument of geologic heritages, which should be ascribable to a hasty designation without an accurate and thorough scientific research. In order to solve these problems and to establish an ideal policy in designating natural monument, National Research Institute of Cultural Heritage has been carrying out a research project of "Pre-study and Post-designation (PSPD)", especially targeting the rod-shaped stromatolite. It is likely that this new strategy of PSPD is a unique and the first step to solve many problems in designating and naming geologic heritages as natural monuments. As a consequence, we strongly suggest that PSPD system must be applied to natural monument designation as an institutional arrangement.