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Quantitative Structure Determinations of Glycine/Cu(100) and Cu(110)

  • Kang, J.H.
    • Journal of the Korean Magnetics Society
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    • v.16 no.1
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    • pp.79-83
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    • 2006
  • The first quantitative structure determination has been obtained for Cu(100)/glycine $(NH_2CH_3COOH)$. The molecule is adsorbed on the surface via two functional groups: the nitrogen of the amino group and one or both two oxygen atoms of the carboxylate group are bonded in near atop site. The Cu-N is tilted $5^{\circ}\pm4^{\circ}C$, away from the surface normal whilst the Cu-O is tilted by $9^{\circ}\pm2^{\circ}C$. The chemical bonding lengths are determined with $2.05\pm0.02\;{\AA}$ for both Cu-N and Cu-O. This bonding geometry is similar to that of glycine on Cu(110). A reanalysis of O Is from the Cu(110)$(2\times3)$pg-glycine show two oxygen atoms are inequivalent, with one being offset $0.29\;{\AA}$ more than the other.

Impact Assessment of Liquid Manure Application on Soil and Shallow Groundwater in Poplar Experimental Site (액비 시비에 따른 포플러시험포 토양수 및 천층지하수 수질 영향 평가)

  • Hong, Eun-Mi;Choi, Jin-Yong;Nam, Won-Ho;Lee, Sang-Hyun;Yoo, Seung-Hwan
    • Journal of The Korean Society of Agricultural Engineers
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    • v.57 no.1
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    • pp.25-35
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    • 2015
  • As livestock manure treatment is becoming a problem, manure application in forest plantation is recommended as an alternative. In this study, to investigate the impact due to liquid manure application in forest plantation, soil, soil water and shallow groundwater quality had been monitored in poplar experimental site where the liquid manure (LM) was applied. Water samples were collected weekly during growing season (April to October) from 2008 to 2011. From the monitoring results, phosphorus concentration in the soil and soil water had no significant difference between LM and control plots. $NO_3$-N concentration of soil water in LM, however, showed higher concentration (13.6 mg/l at 40 cm, 35.1 mg/l at 80 cm) than control plot (1.5 mg/l at 40 cm, 0.5 mg/l at 80 cm). In case of shallow groundwater quality, pH, heavy metal, etc. were satisfied to the national agricultural water quality standard of groundwater and there were no significant difference between upstream and downstream. The $NO_3$-N concentration of shallow groundwater was also not exceeded the national drinking water standard. However, $NO_3$-N concentration in soil water and downstream of shallow groundwater had increased in 2011 when non-composted LM was applied mostly in non-growing season of tree (September). From the results, it is important to control nitrogen source, application time and decomposed or not when LM is applied. In addition, to investigate nitrate source, further long-term monitoring and modelling could be necessary.

Soil Characteristics by the Site Types around Nari Basin in Ulleung Island (울릉도 나리분지의 입지유형별 토양특성)

  • Chung, Jae-Min;Moon, Hyun-Shik
    • Journal of agriculture & life science
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    • v.44 no.6
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    • pp.45-50
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    • 2010
  • Soil characteristics by site types (slope, topography and stand) were analyzed to provide the basic information for sustainable management of Nari basin in Ulleung Island. The content of total N of Nari basin was lowest at the north slope, this site had also significantly low soil pH and content of available P. The result of soil pH and content of total N analysis by topography, ranged from 5.13 of summit to 5.59 of plain and from 0.63% of plain to 0.87% of hill, respectively. Soil pH, content of total N and available P by stand were significantly different, which showed that stand types are more significant in explaining the soil properties. Available P content by slope, topography and stand ranged from 2.79 to 8.46 ppm, 3.99 to 8.46 ppm and 5.03 to 11.59 ppm, respectively. It was concluded that forest soil around Nari basin has relatively low available P content compared to other forest soil.

Amplification based on shear wave velocity for seismic zonation: comparison of empirical relations and site response results for shallow engineering bedrock sites

  • Anbazhagan, P.;Aditya, Parihar;Rashmi, H.N.
    • Geomechanics and Engineering
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    • v.3 no.3
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    • pp.189-206
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    • 2011
  • Amplification based on empirical relations is widely used for seismic microzonation of urban centers. Amplifications are used to represent the site effects of a particular soil column. Many empirical correlations are available to estimate the amplification of seismic waves. These correlations are based on the ratio of shear wave velocity of foundation/rock to soil velocity or 30 m equivalent shear wave velocity ($Vs^{30}$) and are developed considering deep soil data. The aim of this work is to examine the applicability of available amplification relations in the literature for shallow engineering bedrock sites by carrying out site response studies. Shear wave velocity of thirteen sites having shallow engineering bedrock have been selected for the study. In these locations, the depth of engineering bedrock (> 760 ${\pm}$ 60 m/s) is matched with the drilled bore hole. Shear wave velocity (SWV) has been measured using Multichannel Analysis of Surface Wave survey. These sites are classified according to the National Earthquake Hazards Reduction Program (NEHRP) classification system. Amplifications for an earthquake are arrived for these sites using empirical relations and measured SWV data. Site response analysis has been carried out in SHAKE using SWV and using synthetic and real earthquake data. Amplification from site response analysis and empirical relations are compared. Study shows that the amplification arrived using empirical relations does not match with the site response amplification. Site response amplification is much more than empirical values for same shear wave velocity.

Studies on the Decomposition of Leaf Litter Containing Heavy Metals in Andong Serpentine Area, Korea I. Microcosm Experiment (사문암지대의 중금속 함유 낙엽의 분해에 관한 연구 I. Microcosm 실험)

  • Ryou, Sae-Han;Kim, Jeong-Myeong;Shim, Jae-Kuk
    • Korean Journal of Environmental Biology
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    • v.27 no.4
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    • pp.353-362
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    • 2009
  • This study attempted to compare the litter decomposition rate of Arundinella hirta and Miscanthus sinensis var. purpurascens which collected from serpentine soil acting potentially toxic concentration of heavy metals and non-serpentine soil by using the microcosm method for 192 days under constant humidity and $23^{\circ}C$. The contents of Ni, Fe, Mg and Cr in the serpentine and nonserpentine soil originated litter showed high differences between them. The litter samples from serpentine site have lower C/N than non-serpentine litter, but the soluble carbohydrate content was shown almost similar between two plant litter. The mass loss rates of leaf litter from serpentine area were slower than those from non-serpentine site. During the experimental period, the remained dry weight of A. hirta and M. sinensis var. purpurascens litter collected from serpentine site were 64.7%, 65.0% of initial dry weight and litter samples from non-serpentine site showed 54.2%, 50.7%, respectively. K and Na were leached rapidly at the initial decomposition periods, but Ca showed immobilization and other metal elements reserved at the decomposing litter for a long time. The decomposing A. hirta litter from non-serpentine soil showed higher values of $CO_2$ evolution, microbial biomass-C, and microbial biomass-N than those in serpentine soil originated litter acting nutrient stresses and exhibited rapid decay rate. The microbial biomass and microbial respiration of decaying litter were positively correlated with litter decomposition rate, and these relationships showed more rapid slope in non-serpentine soil originated litter than that in serpentine soil.

Site Assessment for the Water Purification Effect of Porous Concrete by using Effective Micro-organisms (유용미생물을 이용한 포러스콘크리트의 수질정화특성에 대한 현장평가)

  • Kim, Bong-Kyun;Park, Jun-Seok;Seo, Dae-Seuk;Kim, Wha-Jung;Kim, Yun-Yung
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.19 no.1
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    • pp.109-119
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    • 2015
  • In recent years, a rapid growth in the population and urbanization led to an increasing industrial growth. The inadequate treated-wasted water from industry and various non-point sources causes significant negative effects on the stream water. For past few decades, extensive researches have been performed on water purification process. The purpose of this study is to investigate mechanical performance and water purification properties of porous concrete by using effective microorganisms through the site assessment test. The mechanical performance evaluation results showed that the increase void ration caused an decrease in the strength. The optimal mix rate was found to be 15% void rate From the site assessment, it was evaluated that the porous concrete improved the quality of the water and the purification ratios are 34.1 for SS, 14.6% for BOD, 34.9% for COD, 11.4% for T-N, and 12.6% for T-P. The porous concrete and the related purification technique can reduce the non-point pollution sources flowing into the river.

Correlation Analysis between Growth and Environmental Characteristics in Abeliophyllum distichum Habitats (미선나무 자생지의 생육특성과 환경특성간의 상관분석)

  • 유주한;조흥원;정성관;이철희
    • Korean Journal of Environment and Ecology
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    • v.18 no.2
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    • pp.210-220
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    • 2004
  • The purpose of this study is to propose the raw data of conservation and restoration by analyzing the environmental and growth characteristics in Abeliophyllum distichum habitats. The types of soil were sandy loam, loam and silty clay loam and the correlation on chemical characteristics of soil appeared that T-N and C.E.C were highly correlative. In case of growth characteristics, height and diameter in 1st site, crown in 2nd site, number of leaves in 5th site and number of seeds in 4th site were better than other sites. In the results of correlation on growth characteristics, height and diameter were highly correlative. In case of growth and chemical characteristics, EC and height were highly correlative. In the results of regression analysis, R-square of height and EC was some 70.4% and that of number of leaves and T-N was some 70.2%. To conserve and restore Abeliophyllum distichum habitats, there were demanded that the accurate environmental analysis that considered such diverse factors as light intensity, temperature, genetic quality and so forth.

Characterization of Insulin-like Growth Factor-free Interaction between Insulin-like Growth Factor Binding Protein 3 and Acid Labile Subunit Expressed from Xenopus Oocytes

  • Choi, Kyung-Yi;Kyung, Yoon-Joo;Lee, Chul-Young;Lee, Dong-Hee
    • BMB Reports
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    • v.37 no.2
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    • pp.153-158
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    • 2004
  • The acid-labile subunit (ALS) is known to interact with the IGF binding protein (IGFBP) in the presence of insulin-like growth factors (IGFs). Studies, however, indicate that ALS forms a doublet with IGFBP3, independent of IGFs. To characterize the structural domain required for the IGF-free ALS-IGFBP3 interaction, seven recombinant human IGFBP3 mutants were generated: three deletion mutants and four site-specific mutants that had altering N-terminal regions of IGFBP3. ALS and IGFBP3 mRNAs were co-injected into Xenopus oocytes, and their products were cross-linked and immunoprecipitated using antisera against ALS or IGFBP3. Among the deletion mutants, the mutant of D40 (deleted in 11-40th amino acids) exerted no effect in the interaction with ALS, while D60 (${\Delta}11$-60) demonstrated a moderate reduction. D88 (${\Delta}11$-88), however, showed a significant decrease. In the case of site-specific mutants, the mutation that alterated the IGF binding site (codons 56 or 80) exerted a significant reduction in the interaction, whereas codons 72 or 87 showed no significant change in the interaction with ALS. The stability of the ALS-IGFBP3 interaction was analyzed according to a time-dependent mode. Consistent with the binding study, mutants on the IGF binding sites (56 or 80) consistently show a weakness in the ALS-IGFBP3 interaction when compared to the mutants that covered the non-IGF binding sites (72 or 87). This study suggests that the N-terminal of IGFBP3, especially the IGF binding site, plays an important role in interacting with ALS as well as in stabilizing the dual complex, independent of IGFs.

Neuronal injury in AIDS dementia: Potential treatment with NMDA open-channel blockers and nitric oxide-related species

  • Lipton, Stuart A.
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1996.04a
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    • pp.19-29
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    • 1996
  • The neurological manifestations of AIDS include dementia, encountered even in the absence of opportunistic superinfection or malignancy. The AIDS Dementia Complex appears to be associated with several neuropathological abnormalities, including astrogliosis and neuronal injury or loss. How can HIV-1 result in neuronal damage if neurons themselves are only rarely, if ever, infected by the vitus\ulcorner In vitro experiments from several different laboratiories have lent support to the existence of HIV- and immune-related toxins. In one recently defined pathway to neuronal injury, HIV-infected macrophages/microglia as well as macrophages activated by HIV-1 envelope protein gp120 appear to secrete excitants/neurotoxins. These substances may include arachidonic acid, platelet-activating factor, free radicals (NO - and O$_2$), glutamate, quinolinate, cysteine, cytokines (TNF-${\alpha}$, IL1-B, IL-6), and as yet unidentified factors emanating from stimulated macrophages and possibly reactive astrocytes. A final common pathway for newonal suscepubility appears to be operative, similar to that observed in stroke, trauma, epilepsy, and several neurodegenerative diseases, including Huntington's disease, Parkinson's disease, and amyotrophic lateral sclerosis. This mechanism involves excessive activation of N-methyl-D-aspartate (NMDA) receptor-operated channels, with resultant excessive influx of Ca$\^$2+/ leading to neuronal damage, and thus offers hope for future pharmacological intervention. This chapter reviews two clinically-tolerated NMDA antagonists, memantine and nitroglycerin; (ⅰ) Memantine is an open-channel blocker of the NMDA-associated ion channel and a close congener of the anti-viral and anti-parkinsonian drug amantadine. Memantine blocks the effects of escalating levels of excitotoxins to a greater degree than lower (piysiological) levels of these excitatory amino acids, thus sparing to some extent normal neuronal function. (ⅱ) Niuoglycerin acts at a redox modulatory site of the NMDA receptor/complex to downregulate its activity. The neuroprotective action of nitroglycerin at this site is mediated by n chemical species related to nitric oxide, but in a higher oxidation state, resulting in transfer of an NO group to a critical cysteine on the NMDA receptor. Because of the clinical safety of these drugs, they have the potential for trials in humans. As the structural basis for redox modulation is further elucidated, it may become possible to design even better redox reactive reagents of chinical value. To this end, redox modulatory sites of NMDA receptors have begun to be characterized at a molecular level using site-directed mutagenesis of recombinant subunits (NMDAR1, NMDAR2A-D). Two types of redox modulation can be distinguished. The first type gives rise to a persistent change in the functional activity of the receptor, and we have identified two cysteine residues on the NMDARI subunit (#744 and #798) that are responsible for this action. A second site, presumably also a cysteine(s) because <1 mM N-ethylmaleimide can block its effect in native neurons, underlies the other, more transient redox action. It appears to be at this, as yet unidentified, site on the NMDA receptor that the NO group acts, at least in recombinant receptors.

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Development of Site Index Equations and Assessment of Productive Areas Based on Environmental Factors for Major Coniferous Tree Species (환경요인에 의한 주요 침엽수종의 지위지수 추정식 개발과 적지 평가)

  • Lee, Yong Seok;Sung, Joo Han;Chun, Jung Hwa;Shin, Man Yong
    • Journal of Korean Society of Forest Science
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    • v.101 no.3
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    • pp.395-404
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    • 2012
  • This study was conducted to develop site index equations and to estimate productive areas for major coniferous species in Korea such as Pinus densiflora Sieb. et. Zucc, Pinus densiflora for. erect, Larix leptolepis and Pinus koraiensis using environmental factors. Using the large data set from both a digital forest site map and a climatic map, a total of 43 environmental factors including 15 climatic variables were regressed on site index by tree species to develop site index equations. Six environmental factors by species were selected as independent variables in the final site index equations. The result showed that the coefficients of determination for site index equations by species were ranged from 0.36 to 0.56, which seem to be relatively low but good enough for the estimation of forest stand productivity. The site index equations developed in this study were also verified by three evaluation statistics such as the estimation bias of model, precision of model, and mean square error of measurement. According to the evaluation statistics, it was found that the site index equations by species fitted well to the test data sets with relatively low bias and variation. As a result, it was concluded that the site index equations by species were well capable of estimating site quality. Based on the site index equations, the productive areas by species for all forest areas were estimated by applying GIS technique to the digital forest site map and climate map. In addition, the distribution of productive areas by species was illustrated by using GIS technique.