• Journal of Pharmacopuncture
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• v.10 no.2 s.23
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• pp.93-98
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• 2007

Objectives : The aim of this study was to observe variation of Bee Venom content from the collection period. Methods : Content analysis of Bee Venom was rendered using HPLC method by standard melittin Results : Analyzing melittin content using HPLC, 478.97mg/g at june , 493.89mg/g at july, 468.18mg/g at August and 482.15mg/g was containing in Bee Venom at september. So the change of melittin contents was no significance from June to September. Conclusion : Above these results, we concluded carefully that collecting time was not important factor for the quality control of Bee Venom, restricted the period from June to September.

• The Journal of Korean Medical History
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• v.22 no.2
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• pp.33-41
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• 2009

The objective of this article is to analysis of Acupuncture & Moxibustion Fix-a-day Method (AMFDM) shown in the acupuncture documents of the Chosun-Korea dynasty. Through such inquisition, The development process of AMFDM could be found. cross-comparison analysis of the contents of three medical books, Chim-Gu-Tek-Il-Pien-Zip(CGTIPZ), Dong-Eui-Bo-Gam(DEBG) and Chim-Gu-Gyung-Hum-Bang (CGGHB) of the Chosun-Korea dynasty. The development process of AMFDM of the three books is different from each other, depending on the purpose of writing books. But The three books contain common parts. It could be divided into three types, Simple-AMFDM, Extensive-AMFDM and Spirit-Existence-AMFDM. The development process of AMFDM of the Chosun-Korea dynasty has three steps. First, Integration and specialization phase in CGTIPZ. CGTIPZ sum many kind of AMFDMs up, and compare them to be specialized area. Second, Setting theory phase in DEBG. DEBG theorize AMFDM made of Spirit-Existence-AMFDM. Third, Practical use phase in CGGHB. CGGHB invented practical reinforcement to replace complicated ones.

• Journal of Pharmacopuncture
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• v.3 no.2
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• pp.233-244
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• 2000

After observing a patient diagnosed with Progressive Muscular Dystropies from the August, 31, 2000 to the January, 2001, the following results are obtained. Method and Result: Under our assumption that the Korean Bee Venom Therapy is a good method to treat Progress Muscular Dystropies. Korean Bee Venom Therapy was applied on the following acupuncture points: BL23(Shinsu:腎兪), BL26(Guanyuanshu:關元兪), ST36(Chok-Samni:足三里), LI4(Hapkok:合谷), LV3(Taechung:太), SP10(Hyolhae:血海), SI9(Sojang-Kyonjong:貞). In addition CFC(Carthami Flos;紅花: and Cervi Pantotrichum Cornu;) Herbal-Acupuncture is also treated on the other acupuncture points. For herbal medication was given to the patient based on the Sasang Constitution, Taeyangin Ogapijangchuk-tang. Following these treatments in this case of Progressive Muscular Dystropies, the skeletal muscle functions made remarkable improvement. Conclusion: Based on the clinical results, traditional Korean Medical treatment is believed to be effective for treating Progressive Muscular Dystropies, and further studies should be conducted to provide more valuable information.

• Journal of Acupuncture Research
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• v.40 no.3
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• pp.177-187
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• 2023

Varicose veins have a substantial burden on individuals' aesthetics and overall quality of life. The current body of research on Korean medical interventions for varicose veins is limited in Korea, and exploration into clinical trends is lacking. This review specifically analyzed fire acupuncture, which is an understudied intervention in Korea that demonstrated efficacy in alleviating pain and paralysis while promoting tissue regeneration. A comprehensive investigation of the China National Knowledge Infrastructure database was conducted, utilizing terms such as "varicose vein," "fire needle," "fire acupuncture," "burning acupuncture," "burning needle," "huǒzhēn," "xiàzhī jìngmài," and "jìngmài qūzhāng." This review included 14 studies investigating the role of fire acupuncture in treating varicose veins. We extracted variables, including age, sex, disease duration, intervention method, treatment frequency, treatment period, acupoints, and outcomes. Fire acupuncture appeared as the primary intervention method, followed by general acupuncture. The protruding part of varicose veins is the main treatment area for fire acupuncture, while the acupoints BL57 and ST36 were most frequently utilized for general acupuncture. Treatment results revealed significant improvement in all studies. However, there are limitations, such as scarce studies, limited side effects studies, and potential bias. Consequently, extensive and well-structured future studies are necessary to demonstrate the role of fire acupuncture in varicose veins.

• Journal of Acupuncture Research
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• v.17 no.4
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• pp.1-4
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• 2000

For checking the exact acupuncture points of Governor Vessel(GV) at lumbar regions, five kinds of method were used to 100 patients who have treated in outpatient in our hospital. They were attached distinguishable stainless steel by the methods. And those were compared with X-ray measuring. As a results, the best method to check Yoyang-gwan(GV3, Ya~oyanggua~n) was the way of using both iliac crests at lateral lying position.

• The Journal of Internal Korean Medicine
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• v.33 no.4
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• pp.543-557
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• 2012

Objectives : The purpose of this study which adopted a qualitative method was to evaluate blood pressure management behaviors of pre- and stage 1 hypertension patients and to provide fundamental data for developing a strategy about proper oriental medical treatment through analyzing factors related to a moxibustion clinical trial. Methods : Semi-structured interviews that focused on personal experiences with hypertension and its management were conducted with 10 hypertensive patients. The interviews lasted for approximately 50 minutes. Results : Most participants recognized that the direct cause of high blood pressure was unhealthy behavior rather than inheritance. Thus, the hypertensive patient believed they could recover their blood pressure to a normal level through removing the direct cause of hypertension instead of taking drugs. The reasons for these statements were that the drugs for controlling hypertension are not natural and they may have side effects. On future management plan of patients, most of them will continue to keep moxibustion and healthy behavior in the well-controlled blood pressure group. However in the uncontrolled blood pressure group, there was an increasing tendency to begin medication. Conclusions : For developing a strategy for an individual approach to hypertension management, we need to develop a client-centered attitude and strategy. That is, we need to tailor our approach to individual cases to avoid generalizations and stereotyping when developing an adherence increasing strategy.

• Journal of Acupuncture Research
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• v.20 no.6
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• pp.89-102
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• 2003

Objective: The expression of CRF(corticotropin releasing factor), CRF-R(receptor) and CRF-BP(binding protein) in CNS neurons projecting to the stomach and ST36 using the pseudorabies virus in the rat was investigated. Methods: After survival times of 5 days following injection of PRV-Ba-Gal, The thirty rats were perfused, and their brain were frozen sectioned($30{\mu}m$). These sections were stained by PRV-Ba-Gal histochemical staining method and(or) CRF, CRF-R and CRF-BP immunohistochemical method. The common expressed areas of the brain projecting to the stomach and zusanli(ST36) following injection of PRV-Ba-Gal were observed with light microscope. Results: 1) The dense accumulation of CRF-immunoreactive terminals is seen in the area postrema, n. tractus solitarius, external zone of the median eminence, with some immunoreactive CRF also present in the internal zone. 2) Aggregates of CRF-R immunoreactive perikarya are found in area postrema, n. tractus solitarius, lateral reticular n., gigantocellular reticular n., locus coeruleues, paraventricular n. of hypothalamus, median eminence, preoptic n., arcuate n. and hind limb area of cerebral cortex. 3) Aggregates of CRF-BP immunoreactive perikarya are found in area postrema, n. tractus solitarius, lateral reticular nucleus, gigantocellular reticular n., locus coeruleues, paraventricular n. of hypothalamus, median eminence and arcuate n.. Conclusions : These results suggest that PRV-Ba-Gal labeled areas projecting to stomach and ST36 may be related to the central autonomic pathways. A part of CNS neurons projecting to the stomach and ST36 were related to expression of CRF, CRF-R and CRF-BP related to the stress in central autonomic center.

• Journal of Oriental Neuropsychiatry
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• v.25 no.2
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• pp.165-178
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• 2014

Objectives: This study was conducted to assess how Traditional Chinese Medicine treats the medical condition of Restless Legs Syndrome (RLS). Methods: The authors searched for relevant articles through the CNKI (China National Knowledge Infrastructure-www.global.cnki.net) with the following keywords: The main search was for the term 'RLS,' with supportive words added such as 'Acupunture', 'Acupoint', 'Meridian', 'Moxibustion', 'Massage', 'Acupoint injection'. Our search yielded a total of 233 articles; there were a total of 71 articles related to clinical fields. We then analyzed the chosen articles using a number of criteria including the study type used, the treatment method utilized, and the main effect of the treatment. Results: The 71 analyzed articles utilized the following type of study design: 4 were classified as Quasi-randomised trial, 22 as Randomized Controlled Trial, and 45 as a case report. Regarding the treatment used for RLS, 25 studies examined a single treatment modality, while 46 studies examined a complex treatment modality. There were a total of 10 types of acupuncture treatment used in treating RLS; several massage and acupoint injection method were also found. Finally, there were a few studies that used Moxibustion, as well as several supportive treatments like Cupping, Moxibustion, Steam-Washing, TDP (Teding Dancibo Pu) were found. Conclusions: Traditional Chinese Medicine has used a variety of different study designs and treatments vis-a-vis RLS. These treatments are also used to treat the condition in South Korea.

• Journal of Acupuncture Research
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• v.19 no.2
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• pp.92-104
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• 2002

Objective : Bee venom (BV) has traditionally been used in Oriental medicine to relieve pain and to treat inflammatory disease such as rheumatoid arthritis (RA). Autoimmunity to type II collagen (CII) may involve in the pathogenesis of RA. This study was performed to evaluate the effect of BV on type II collagen induced arthritis (CIA) with the naked eye, a immunohistochemical method and the examination of histology. Method : Male mice were immunized by subcutaneously injection of an $200{\mu}g$ emulsion mixed with bovine CII and complete Freund's adjuvant (CFA) twice for two weeks. In the control group, normal saline was injected, and in the experimental group, BV was applied. Result : The incidence of arthritis, the mean arthritis index and the number of the arthritic limbs of the BV group were all significantly lower than those of the control group. Among the pro-inflammatory cytokines, the production of $TNF-{\alpha}$ in the BV group was also suppressed compared with the control group, but $IL-1{\beta}$ was not. The examination on the histopathology of joints of CIA mice showed the effect of Bee Venom Herbal Acupuncture on the arthritis. Conculusion : Treatment with BV resulted in inhibition of development of arthritis and immune responses to CII.

• Journal of Acupuncture Research
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• v.29 no.5
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• pp.61-74
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• 2012

Objectives : This study is perfomed for preparation of oriental medicine clinical guidelines for drawing up the standards of oriental medicine demonstration and diagnosis classification about the knee pain. Methods : Statistical analysis about Crane's-knee wind(鶴膝風), arthralgia syndrome(痺症), knee injury(膝傷), gout arthritis(痛風), Youk jeol poung(歷節風) classified experts' opinions about knee pain patients by Delphi method is conducted by using oriental medicine diagnosis questionnaire. The result was classified by using linear discriminant analysis(LDA), diagonal linear discriminant analysis(DLDA), diagonal quadratic discriminant analysis(DQDA), K-nearest neighbor classification(KNN), classification and regression trees(CART), support vector machines(SVM). Results : The results are summarized as follows. 1. The result analyzed by using LDA has a hit rate of 81.65% in comparison with the original diagnosis. 2. The result analyzed by using DLDA has a hit rate of 63.3% in comparison with the original diagnosis. 3. The result analyzed by using DQDA has a hit rate of 65.14% in comparison with the original diagnosis. 4. The result analyzed by using KNN has a hit rate of 74.31% in comparison with the original diagnosis. 5. The result analyzed by using CART has a hit rate of 75.23% in comparison with the original diagnosis when the test of selected 13 significant questions based on analysis of variance was performed. 6. The result analyzed by using SVM has a hit rate of 87.16% in comparison with the original diagnosis. Conclusions : Statistical analysis using oriental medicine diagnosis questionnaire on knee pain generally turned out to have a significant result.