• Biotechnology and Bioprocess Engineering:BBE
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• v.11 no.2
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• pp.110-115
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• 2006

We conducted a sensitivity analysis of the simulated moving bed (SMB) chromatography with the case model of the separation of two amino acids phenylalanine and tryptophan. We consider a four-zone SMB chromatography where the triangle theory is used to determine the operating conditions. Competitive Langmuir isotherm model was used to determine the adsorption isotherm. The finite difference method is used to solve nonlinear partial differential equation (PDE) systems numerically. We examined the effects of alterations in the operating conditions(feed-extract, feed-raffinate, eluent-extract, eluent-raffinate, recycle, and switching time) and the adsorption isotherm parameters (Langmuir isotherm parameters a and b) on SMB efficiency. The variation range of operating conditions and Langmuir isotherm a was between -50 and 50% of original value and the variation range of the Langmuir isotherm b was between $2.25^{-5}$ and $2.25^5$ times of original value.

• KSBB Journal
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• v.15 no.6
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• pp.541-547
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• 2000

Simulated moving bed (SMB) chromatography has been investigated in order to separate chiral compounds for pharmaceutical use. SMB utilizes the principle of true moving bed (TMB) chromatography, and has the advantages of low solvent usage, flexible configuration of columns and hardwares, and high productivity of the chiral compounds over the TMB. Large scale separation of xylene isomers and saccharides has been conducted since 1960s. However, the application of SMB in the fine chemical industries is still in the infant stage. The study of SMB for the chiral compounds production was initiated in the mid 1990s and further researches are actively undergoing. This review summarizes the principle of SMB as well as the chemistry of chiral stationary phase and chiral compounds.

• International Journal of Railway
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• v.2 no.4
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• pp.180-186
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• 2009

High speed railway challenge the design, construction and maintaining of traditional railway, many traditional design concepts have been changed. Transition of railway and bridge has two main problems. one is that different lines have different ability of resisting distortion in area of trial load, which was known that problem of smooth transition of stiffness, the other is that differential settlement between artificial structure and earth structure cause bending of railway. The two problems have effect on train moving. The principle of processing transition of railway and bridge is same in world, but it is difficult to find relationship between design standard of transition, vehicle performance, line standard, design speed and so on form documentation and data reports. Based on mechanics, the paper analyzed dynamic performance of transition of high speed railway, studied various rough elements which is effective to train moving, built mathematical model of interaction of train and transition of high speed railway and developed numerical simulation software. In various different work conditions, we did great quantity of numerical simulation, comprehensive analysis and performance analysis.

• Journal of the Korea Society of Computer and Information
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• v.22 no.11
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• pp.17-23
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• 2017

In this paper, we implemented a respiration measurement system consisting of piezoelectric sensor, respiration signal processing device, and a viewer on a notebook. We tried an experiment for measuring respiration and detecting sleep apnea syndrome when a subject lay on a bed. We applied the respiration measurement algorithm to sensor data obtained from four subjects. In order to get a good graph shape, data manipulation methods such as moving averages and maximum values were applied. The window size for moving average was chosen as N=70, and the threshold value for each subject was customized. In this case, the proposed system showed 96.0% accuracy. When the maximum value among 90 data was applied instead of moving average, our system achieved 95.1% accuracy. In an experiment for detecting sleep apnea syndrome, the system showed that sleep apnea occurred correctly and calculated the average interval of sleep apnea. While infants or the elderly as well as patients with sleep apnea syndrome are lying down on a bed, our results are also expected to be able to cope with some accidental emergency situation by observing their respiration and detecting sleep apnea.

• 한국생물공학회:학술대회논문집
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• 2005.10a
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• pp.565-565
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• 2005

• Journal of the Korean Society of Safety
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• v.16 no.3
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• pp.41-44
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• 2001

The removal characteristics of nitrogen oxides (NOx) by the dielectric ($Al_2O_3$) packed-bed plasma reactor are experimentally investigated Reactor is packed with 5[mm] diameter $Al_2O_3$ beads, and was desisted to remove NOx at atmospheric pressures from the moving pollution source such as diesel automobile. The experiments were conducted for applied voltages from 5 to 10[kV], flue gas rate from 2 to 5[l/min] and frequency from 0.5 to 2[kHz]. The NOx removal efficiency significantly increasing with increasing applied voltage. Especially removal rate significantly increased with increasing frequency. However, in this experiment discharged poler n relatively high.

• Vacuum Magazine
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• v.3 no.2
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• pp.11-16
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• 2016

Tidal current energy is the most interesting renewable resources that have been less harnessed. Korea has globally outstanding tidal current energy resources and it is highly needed to develop a tidal current energy conversion system. It is reported that the total amount of available tidal current energy is approximately 6GW in Korea. A good tidal site candidate is required a large amount of fast moving water, bathymetry and seabed properties, no conflicts with other users and is close to a load and grid interconnection. In this review, we summarized the results of R&D projects regarding tidal current resources, utilization projects and demonstration test bed.

• Korean Chemical Engineering Research
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• v.43 no.6
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• pp.715-721
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• 2005

The SMB chromatography is used to obtain high purification of fructooligosaccharides (FOS), the mixture of kestose and nystose. SMB operation condition is usually determined by triangle theory or standing wave design when reactions do not occur within columns during experiment. Some of the reactions in columns may considerably affect experimental results. FOS can be hydrolyzed and converted into glucose and fructose during operation. To include the effect of reaction, the concentrations of each component at steady state after hydrolysis were used in simulation. The obtained simulation values are well matched with experimental results except sucrose. For sucrose, the experimental results were different from expected one due to the existence of an intermediate component. FOS is easily hydrolyzed and converted into glucose and fructose in more acidic condition and at higher temperature. Hydrolysis reaction can be prevented by the pretreatment of separation resin with NaOH as well as operation under lower temperature.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.56 no.6
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• pp.870-877
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• 2023

The purpose of this study was to assess the efficiency of nitrification based on ammonia loading rates and hydraulic air-loading rates in a moving bed bioreactor (MBBR) under seawater conditions. The goal was to provide foundational data for the design of these bio reactors. At an ammonia loading rate of 0.2 g TAN·m^-2 surface area·day^-1, the influent TAN concentration was determined to be 1.76±0.33 mg·L^-1, which is below the safe concentration for fish survival (2 mg·L^-1). Considering operational aspects, the optimal ammonia-loading rate was derived. Subsequently, experimental results for nitrification efficiency at the optimal ammonia-loading rate revealed that the optimum hydraulic air-loading rate was 1.8 L·air·m^-2 surface area·min^-1. This condition resulted in the lowest concentrations of TAN and NO₂-N in the influent water, thus establishing the optimal hydraulic air-loading rate. A regression equation was derived for the ammonia-removal rate (Y) based on the ammonia-loading rate (x) and expressed as a 0.5-order equation (Y=ax^0.5+b). Specifically, for TAN concentrations of 0-6 mg·L-1, the regression equation Y=0.1683x^0.5-0.13628, was established.

• Korean Journal of Agricultural Science
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• v.38 no.1
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• pp.101-108
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• 2011

In forest work, working conditions are very hard to improve. The proper distribution of work time and good posture is believed to bring about direct improvements such as accident prevention. On this, this study has analyzed forest workers' posture and their working hours in order to improve their working conditions in stone channel work. Authors has chosen several core elements of stone channel work to focus on, which include stone masonry, excavation of bed, moving stone, directing work, choosing stone, and breaking stone. The ratio of real working time over total working time was shown as 84.6%. As for the time ratio of each elemental work over the real working time, the stone masonry was 60.4%, the directing work was 15.1%, moving stone was 12.1%, choosing stone was 7.1%, breaking stone was 3.3%, and excavation of bed was 2.0%. According to the analytical results provided by OWAS, the ratio of category III (Work posture has a distinctly harmful effect on the musculoskeletal system) has shown that moving stone turned out 65.2%, choosing stone was 61.5%, stone masonry was 46.1%, breaking stone was 14.3%, excavation of bed was 12.5% and directing work was 6.8%. Furthermore, the ratio of category IV (Work posture with an extremely harmful effect on the musculoskeletal system) has shown that excavation of bed turned out 37.5%, breaking stone was 28.6%, stone masonry was 27.3%, choosing stone was 7.7%, moving stone was 6.1% and directing working was 4.5%. These results are expected to be utilized for the improvement with respect to both working methods in the stone channel work and the workers' working posture.