• Korean Journal of Acupuncture
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• 제29권2호
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• pp.260-270
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• 2012

Objectives : Hippocampus, a region of temporal lobe, plays an important role in the pathogenic mechanisms of brain diseases such as Alzheimer's disease, depression and temporal lobe epilepsy. This research is designed to investigate hippocampal changes after acupuncture stimulation at Shinmun(HT7) using 2-dimensional gel electrophoresis(2-DE). Methods : On postnatal-day 15, rat pups were randomly devided into Normal(NOR) or HT7 group. All of Pups kept with their mothers for 7 days, but pups in HT7 group received acupuncture stimulation at HT7 daily. On postnatal-day 21, hippocampus of each rat pup was dissceted 30 minutes after last acupuncture stimulation and the protein expressions were investigated using 2-DE. Results : After acupuncture stimulation at HT7, expression of 20 proteins were significantly increased. Succinate semialdehyde dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase-like, transketolase, aconitate hydratase and phosphoglucomutase-1 were related to glucose methabolism. Eukaryotic initiation factor(eIF) 4A-II, eIF 4A-III, mitochondrial Tu translation elongation factor and chain A of crystal structure of the 70-Kda heat shock cognate protein involve in the protein synthesis in ribosome. Tubulin ${\beta}$-4 chain, tubulin T ${\beta}$-15 and tubulin ${\alpha}$-1B chain comprise cytoskeleton. Glutathione S-transferase(GST) ${\omega}$-1, GST P and GST Yb-3 can reduce oxidative stress. ${\beta}$-soluble N-ethylmaleimide-sensitive fusion protein attachment protein is required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus, glycerol-3-phosphate dehydrogenase plays a major role in lipid biosynthesis, creatine kinase U-type catalyses the conversion of creatine and consumes adenosine triphosphate to create phosphocreatine and adenosine diphosphate. Platelet-activating factor acetylhydrolase IB subunit alpha and voltage depedent anion-selective channel protein 2 were also increased. Conclusions : The results suggest that acupuncture stimulation at HT7 may enhance glucose and lipid metabolism, protein synthesis, cytoskeletal substance and anti-oxidative stress in hippocampus.

• 한국생활과학회지
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• 제20권3호
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• pp.521-532
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• 2011

The study's purpose was to clarify childcare's impact on the psychological well-being of fathers with an infant. This study included 1,250 households that used 15 nursery centers. The questionnaire asked about the fathers' age, income, working conditions, participation in childcare, recognition of sense of usefulness to their family, marital satisfaction, mental health, health-related quality of life(QOL), and the mothers' age, number of children, age of the youngest child, and working conditions. A casual model was examined using SEM. The results were as follows: first, fathers' participation in childcare contributed to health-related QOL through the recognition of feeling useful to their family. Second, fathers' participation in childcare contributed to marital satisfaction, directly and indirectly through health -related QOL and improved mental health. Third, fathers' participation in childcare contributed to health related QOL through the recognition of feelings of usefulness, marital satisfaction, and mental health, indirectly. These results suggest that promoting fathers' participation in childcare is important to help prevent many problems and to improve QOL.

• Child Health Nursing Research
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• 제24권1호
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• pp.58-67
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• 2018

Purpose: This prospective study aimed to examine the development of premature infants at 12 and 24 months and to explore the factors related to their development. Methods: Of the 80 premature infants who were recruited, 52 participants at 12 months and 31 participants at 24 months were included in this study. The development of the infants was examined using the Korean Bayley scale of infant development-II. Postnatal depression, husband's support, social support, mother-infant attachment, and the home environment were assessed using self-report questionnaires completed by the mothers and through the researcher's observations. Results: There was significant difference between normal and delay group at psychomotor development at 12 months depending on social support at 6 months (t=2.03, p=.049). Mother-infant attachment at 6 months (r=.71, p<.001), 12 months (r=.37, p=.043), and 24 months (r=.40, p=.026), as well as social support (r=.38, p=.034) and the home environment (r=.41, p=.022) at 24 months, were correlated to mental development at 24 months. There was a significant positive correlation between mother-infant attachment at 6 months and psychomotor development at 24 months (r=.40, p=.046). Conclusion: To reduce the risk of developmental delay and to promote healthy development in premature infants, early nursing interventions targeting mother-infant attachment, the home environment, and the mother's social support structure are needed.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제10권2호
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• pp.195-200
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• 1999

가족 내의 위험 요인들은 아동의 행동 문제와 밀접한 관련이 있다. 본 연구에서는 소아정신과를 방문해 ADHD로 진단된 아동 29명과 정상 아동 180명의 어머니를 대상으로 가족 내의 환경적 요인과 아동 의 행동 문제에 대한 평가 척도를 실시하였다. ADHD 아동의 자료는 내원 당일 작성해 제출하도록 하였으며, 정상 아동의 자료는 아동을 통해 부모에게 질문지를 배부 ${\cdot}$ 수거하였다. 정상 아동의 자료 중 응답 누락 등을 이유로 49명을 제외한 나머지 131명의 자료와 ADHD 29명의 자료를 분석에 포함시켰다. 연구 결과, 가족환경적 요인들 중에서 결혼만족도, 어머니의 상태-특질 불안, 우울감이 ADHD 집단과 정상 집단간에 통계적으로 유의미한 차이를 나타냈으며 ADHD 증상에 대한 유의미한 설명력을 지녔다. 또한 이러한 가족환경적 요인들과 아동의 행동 문제간에는 통계적으로 유의미한 상관이 있었다. 가족 내의 위험 요인들 중 결혼만족도, 어머니의 정서상태가 ADHD 증상과 밀접한 관련이 있음이 확인되었다.

• 부모자녀건강학회지
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• 제2권
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• pp.53-63
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• 1999

The purpose of this study is to describe how what influence sexuality has on women's health. Sex is determined by the sex chromosome: but sociocultural norms have much influence on the sex role of a woman or man. Women's sexuality has had a negative impact on them in a male-dominated society, which destroyed women's health, put women in a powerless position and forced them to live as dependent persons. Sociocultural perception of the sex role has not been very open, and very strict rules have controlled those perceptions; but currently these perceptions have been changing dramatically. Especially, women's sex role has changed, bringing about many problems: the number of women engaging in premarital sex, the number of unwed mothers, the number of pregnancies without marriage, the divorce rate, and the number of dysfunctional families have all increased. Those kinds of problems have negative effects on women, children and members of the whole family. Sexually transmitted disease because of free sex is a serious health issue for women: the number of women with AIDS has increased rapidly. Another big issue is sexual abuse, which is insulting to women, decreases women's self-esteem, increases depression, puts women in a powerless position and eventually causes women to get sick. Male-preference (among newborns) ideology raises health issues for women, such as artificial abortion. In the area of sex differentiation, therefore, we have to change people's thinking from male-preference ideology to equal sex preference. Finally, we have to use a holistic approach for women's health and increase awareness of the fact that the sex role and women's health are very important for the family, society and nation. Women's health is the nation's power.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제27권3호
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• pp.186-195
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• 2024

Purpose: Infantile colic diagnostic criteria were established by Rome IV. A universally accepted management remains to be established. We aimed to evaluate diagnostic criteria, management strategies, and perceived regional prevalence of infantile colic in Pakistan, as well as its effect on physicians and parents. Methods: A questionnaire was distributed amongst 1,256 physicians. Results: We received 800 replies. Wessel and Rome IV criteria were used by most physicians for diagnosis; however, the response "any infant who cries a lot" was selected by older physicians (48% of those over 60 years), physicians in rural areas (32%), physicians practicing in private clinics (27%), and general physicians (30%). Estimated prevalence of infantile colic ranges from 21-40%. Reassurance was the most widely recommended management strategy followed by herbal teas (51%), switching to a different formula (49%), probiotics (28%) and antibiotics (26%), discontinuation of breastfeeding (14%), elimination of dairy products from the breastfeeding mothers' diet (6%), and the administration of colic drops (1%). Most physicians considered the negative impact of colic on their personal lives and the parents as mild-to-moderate. Notably, 38% of percent of physicians routinely screened for maternal depression, and 45% of physicians were aware of the association between infantile colic and shaken baby syndrome. Conclusion: Most physicians in Pakistan diagnose and manage infantile colic according to the established guidelines. However, the guidelines pertaining to treatment planning are not followed. Educational efforts directed toward general physicians and doctors practicing in rural areas and clinics must be implemented to avoid unnecessary testing and treatment burden.

• 여성건강간호학회지
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• 제29권4호
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• pp.302-316
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• 2023

Purpose: This study aimed to develop and validate a structural model for the quality of life (QoL) among high-risk pregnant women, based on Roy's adaptation model. Methods: This cross-sectional study collected data from 333 first-time mothers diagnosed with a high-risk pregnancy in two obstetrics and gynecology clinics in Cheonan, Korea, or participating in an online community, between October 20, 2021 and February 20, 2022. Structured questionnaires measured QoL, contextual stimuli (uncertainty), coping (adaptive or maladaptive), and adaptation mode (fatigue, state anxiety, antenatal depression, maternal identity, and marital adjustment). Results: The mean age of the respondents was 35.29±3.72 years, ranging from 26 to 45 years. The most common high-risk pregnancy diagnosis was gestational diabetes (26.1%). followed by preterm labor (21.6%). QoL was higher than average (18.63±3.80). Above-moderate mean scores were obtained for all domains (psychological/baby, 19.03; socioeconomic, 19.00; relational/spouse-partner, 20.99; relational/family-friends, 19.18; and health and functioning, 16.18). The final model explained 51% of variance in QoL in high-risk pregnant women, with acceptable overall model fit. Adaptation mode (β=-.81, p=.034) and maladaptive coping (β=.46 p=.043) directly affected QoL, and uncertainty (β=-. 21, p=.004), adaptive coping (β=.36 p=.026), and maladaptive coping (β=-.56 p=.023) indirectly affected QoL. Conclusion: It is essential to develop nursing interventions aimed at enhancing appropriate coping strategies to improve QoL in high-risk pregnant women. By reinforcing adaptive coping strategies and mitigating maladaptive coping, these interventions can contribute to better maternal and fetal outcomes and improve the overall well-being of high-risk pregnant women.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제26권4호
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• pp.258-265
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• 2015

Objectives : Children with attention-deficit hyperactivity disorder (ADHD) have problems in social interactions. We compared the effect of 10-session social skill training (SST) among two groups, children with pure ADHD, and those with ADHD with comorbidity. Methods : Consecutive 10-session SST was conducted for 34 children from 2006 to 2012. There were 22 children with pure ADHD (male 20, female 2), and 12 children suffering from ADHD with comorbidity (male 11, female 1). All children took medication as prescribed by their doctors before the start of SST. The Child Behavior Checklist (CBCL), the Korean Personality Inventory for Children (K-PIC), the Conner's Rating Scale, the ADHD Rating Scale, and the Home Situation Questionnaire were completed by mothers before and after the SST. All children completed the Child Depression Inventory, the Stat-Trait Anxiety Inventory for Children, the Self-Concept Scale and the ADHD Diagnostic System before and after the SST. Results : Only children with pure ADHD showed improvement in anxiety and self-concept in scales rated by children. In the CBCL rated by parents, the pure ADHD group and the ADHD with comorbidity showed improvement in both externalizing and internalizing subscales. In the K-PIC rated by parents, the pure ADHD group showed improvement in most outcomes and ADHD with comorbidity showed positive change in verbal development. Conclusion : These results suggest that SST has significant positive effects on both the pure ADHD and ADHD with comorbidity group. Further research is needed in order to target diverse comorbidity groups with ADHD to improve the effectiveness of the SST.

• 한국콘텐츠학회논문지
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• 제18권12호
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• pp.161-172
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• 2018

본 연구는 치매어머니의 요양보호시설 입소과정을 통해 중년기 여성의 모녀관계 경험을 심층적으로 살펴보고자 하였다. 이를 위해 치매어머니가 요양보호시설에 입소한 중년 여성 8명을 연구대상으로 하였으며, 자료 수집은 개별적인 심층면담을 통하여 이루어졌다. Colazzi의 현상학적 방법론을 바탕으로 연구를 진행하여 분석한 결과 17개의 주제묶음과 6개의 하위범주, 3개의 범주가 도출되었다. 연구결과는 첫째, 치매어머니가 요양보호시설 입소과정에서 모녀관계가 극적으로 역전되는 경험을 하는 것으로 나타났다. 둘째, 치매어머니의 요양보호시설 입소과정에서 아들보다 딸이 치매어머니의 돌봄과 관리에 주체적인 입장에 있는 것이 확인되었다. 셋째, 치매어머니의 요양보호시설 입소 과정에서 급격한 모녀관계 변화, 나아가 가족관계의 전환으로 우울증과 불안, 상실감 등을 경험하는 것으로 나타나 이를 수용하고 대처할 수 있도록 요양보호시설 입소가족을 위한 교육 또는 상담 프로그램을 운영해야 함을 제안하였다.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제13권1호
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• pp.177-188
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• 2002

연구 목적：정신과 치료를 받고 있는 청소년 중 외톨이 혹은 왕따인 청소년과 비외톨이인 청소년의 문제 행동 및 이들의 어머니의 양육 태도를 비교 분석한다. 연구 방법：청소년 정신과 환자 25명에게 외톨이 설문지, 왕따 설문지를 작성하도록 하였고, 이들의 어머니에게 아동청소년 행동평가척도(Child Behavior Checklist, CBCL)중 8개 하위 요인, 자녀양육태도 척도(Maternal Behavior Research Instrument, MBRI)의 일부, 자녀에 대한 관심 척도 등을 작성하도록 하였다. 외톨이 설문지 및 왕따 설문지 점수를 근거로 15명의 외톨이-왕따 집단과 10명의 비외톨이 집단으로 나눈 뒤, 두 집단 간의 나머지 설문지 점수를 비교하였고, 또한 외톨이 설문지와 왕따 설문지의 점수와 나머지 설문지 점수의 상관관계를 알아보았다. 결 과：1) CBCL의 8개 하위 요인(p<.05), 우울/불안 하위 요인(p<.05) 및 사고 문제 하위 요인(p<.01)에서 외톨이-왕따 집단의 점수가 비외톨이 집단의 점수보다 유의하게 높았다. 또한, 외톨이 설문지 점수는 CBCL의 8개 하위 요인(r=.516), 우울/불안 하위 요인(r=.483), 사고 문제 하위 요인(r=.651), 사회적 미성숙 하위요인(r=.517)과 유의한 상관관계를 보였으며, 왕따 설문지 점수는 CBCL의 주의력 문제 하위 요인(r=.414), 사고 문제 하위 요인(r=.446), 사회적 미성숙 하위 요인(r=.531)과 유의한 상관관계를 보였다. 2) 그러나, MBRI 점수 및 자녀에 대한 관심 척도 점수에서는 두 집단간에 유의한 차이를 보이지 않았으며, 외톨이 설문지 혹은 왕따 설문지 점수와 MBRI 점수 혹은 자녀에 대한 관심 척도 점수 사이의 상관관계에서도 통계적으로 유의한 결과를 보이지 않았다. 결 론：정신과 치료를 받고 있는 청소년 중 외톨이-왕따에 해당되는 청소년의 어머니는 비외톨이 청소년의 어머니보다 자녀들의 사고 문제 및 우울/불안 등의 정서적 문제를 더 높게 평가하였다. 그러나, 자녀들에 대한 양육 태도에 대해서는 차이를 두지 않는 것으로 보인다. 향후 보다 많은 환자들을 대상으로 한 추가 연구가 필요할 것이다.