• The Korean Journal of Applied Statistics
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• v.22 no.2
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• pp.317-327
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• 2009

In adaptive designs important components of clinical trials may be changed based on the results of interim analysis. Several international guidelines point out that such interim analysis should be performed by independent experts who do not participate in clinical trials when adaptive designs are used in therapeutic confirmatory clinical trials, and if not, it may cause bias. The international guidelines recommend the establishment of independent data monitoring committee for conducting interim analysis independently.

• The Journal of Asian Finance, Economics and Business
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• v.8 no.5
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• pp.151-156
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• 2021

This paper empirically examines the relationship between one of the major corporate governance attributes; family ownership and the audit committee activity across a sample of 430 publicly traded firms on the Saudi Stock Exchange (Tadawul) for the period 2012-2019. Using the Pooled OLS regression, this study finds that family ownership is negatively associated with audit committee activity. This study reported that family ownership is negatively associated with audit committee activity, giving support to the convergence-of-interest hypothesis. Therefore, the existence of family ownership as a monitoring corporate governance mechanism substitutes the audit committee activity as another monitoring mechanism. This study provides empirical evidence on the associations of two internal corporate governance mechanisms, namely; family ownership and audit committee activity in the Saudi context where there is a paucity of research in this area. The findings of this study provide a new understanding regarding the extent to which family ownership impacts the activity of audit committees in manufacturing companies. Similarly, the companies' management, external auditors, bankers, and companies would also benefit from understanding the influential factors of the audit committee activities.

• The Journal of Asian Finance, Economics and Business
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• v.8 no.4
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• pp.363-368
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• 2021

This study attempts to examine whether ownership of government-controlled corporations and audit committee effectiveness are related. The population of this study is 431 listed manufactured firms in the Saudi Stock Exchange (Tadawul) for the period 2012-2019 that published their financial and annual reports for the period 2012-2019. This population criterion is based on considerations that manufacturing companies listed on Tadawul have publicly accessible data and they have greater obligations to implement corporate governance code. Using the complementary hypothesis, this study predicts that there is a positive relationship between the ownership of government-controlled companies and audit committee effectiveness. The Pooled OLS regression shows that government-controlled companies' ownership is positively associated with audit committee effectiveness. Our study also indicates that ownership of government-controlled companies as a governance monitoring mechanism becomes more effective as it is combined with audit committee effectiveness which is another governance monitoring mechanism. The results of this study provide insightful evidence to policymakers at the company and country levels on the relationship of government-corporate ownership and audit committee effectiveness.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.23 no.4
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• pp.347-355
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• 2013

A damage estimation method for monopile support structure of offshore wind turbine using modal properties and committee of neural networks is presented for effective structural health monitoring. An analytical model for a monopile support structure is established, and the natural frequencies, mode shapes, and mode shape slopes for the support structure are calculated considering soil condition and added mass. The input to the neural networks consists of the modal properties and the output is composed of the stiffness indices of the support structure. Multiple neural networks are constructed and each individual network is trained independently with different initial synaptic weights. Then, the estimated stiffness indices from different neural networks are averaged. Ten damage cases are estimated using the proposed method, and the identified damage locations and severities agree reasonably well with the exact values. The accuracy of the estimation can be improved by applying the committee of neural networks which is a statistical approach averaging the damage indices in the functional space.

• Proceedings of the Technology Innovation Conference
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• 1997.07a
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• pp.266-285
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• 1997

This paper addresses a methodology for monitoring the first phase('92-'94) progress and its strategic implication of Highly Advanced National R&D Program(HAN or G7 project) in Korea. The conceptual framework and its strategic thrust of the interim evaluation, which is the main focus of this paper, was designed both by reviewing related literature and by analyzing the unique characteristics of the HAN Program. Actual monitoring or interim evaluation was initiated by the G7 Planning and Evaluation Committee, which was established for advising, directing, and monitoring the HAN Program, with the help of large number of experts from various industries, universities, and research institutes. The monitoring results had been reported to the related ministries and project coordinating agencies. According to the suggestion made by the G7 Planning and Evaluation Committee, several projects were suffered structural changes and one was dropped.

• Korean Journal of Clinical Pharmacy
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• v.26 no.2
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• pp.181-186
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• 2016

Background: There has been on increasing emphasis on the importance of monitoring the safety of participants in a clinical trial to protect patients and maintain the integrity of the trial. The independent data monitoring committee (IDMC) has become common component of randomized clinical trials in recent years. Methods: It is important to consider the implications of different approaches that are being used in various countries. IDMC guidelines in Korea, US, and Europe were reviewed and compared to provide the objective, composition and operation of IDMC in detail. Results: IDMC is a group of experts in related subject are as who perform interim data monitoring to make a recommendation to the sponsor or organizer regarding appropriateness of trial continuation and the need for modifications of the trial. Independence of IDMC is preferred in order to minimize influence of factors unrelated to scientific, medical and ethical considerations that should underlie decision-making. Conclusion: IDMC has become an increasingly important component of clinical trials in recent years. Practical operating procedures need to be developed considering the future regulatory status of data monitoring committees.

• KCID journal
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• v.10 no.2
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• pp.75-87
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• 2003

• KCID journal
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• v.10 no.2
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• pp.118-122
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• 2003

• KCID journal
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• v.9 no.2
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• pp.110-118
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• 2002

• Explosives and Blasting
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• v.17 no.1
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• pp.3-10
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• 1999