• Title/Summary/Keyword: molecular profile

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A Numerical Study of a Free Molecular Flow in the Turbomolecular Pump (터보 분자 펌프(Turbomolecular pump)내의 자유 분자 유동에 관한 수치 해석적 연구)

  • Hwang, Y.K.;Heo, J.S.
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.8 no.2
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    • pp.219-229
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    • 1996
  • In the free molecular flow range, the pumping performance of a turbomolecular pump has been predicted by calculation of the transmission probability employing the integral method and the test particle Monte-Carlo method. The velocities of molecules incident upon a moving blade are given by the random numbers, which are sampled from the Maxwell molecular velocity distribution function. The present results agree quantitatively with the previous known numerical results. For a multi-stage pump, the velocity profile of molecules between two blade rows is not Maxwell distribution. In this case, the Monte-Carlo method is employed to calculate the overall transmission probability for the entire set of blade rows. When the results of the approximate method combining the single stage solutions are compared with those of the Monte-Carlo method for the pump having six rows at C=0.6, the approximate method overestimates as much as 36% in the maximum compression ratio and 19% in the maximum pumping speed than does the Mote-Carlo method.

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Synchrotron X-ray Reflectivity Studies on Nanoporous Low Dielectric Constant Organosilicate Thin Films

  • Oh, Weon-Tae;Park, Yeong-Do;Hwang, Yong-Taek;Ree, Moon-Hor
    • Bulletin of the Korean Chemical Society
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    • v.28 no.12
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    • pp.2481-2485
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    • 2007
  • Spatially resolved, quantitative, non-destructive analysis using synchrotron x-ray reflectivity (XR) with subnano-scale resolution was successfully performed on the nanoporous organosilicate thin films for low dielectric applications. The structural information of porous thin films, which were prepared with polymethylsilsesquioxane and thermally labile 4-armed, star-shaped poly(ε-caprolactone) (PCL) composites, were characterized in terms of the laterally averaged electron density profile along with a film thickness as well as a total thickness. The thermal process used in this work caused to efficiently undergo sacrificial thermal degradation, generating closed nanopores in the film. The resultant nanoporous films became homogeneous, well-defined structure with a thin skin layer and low surface roughness. The average electron density of the calcined film reduced with increase of the initial porogen loading, and finally leaded to corresponding porosity ranged from 0 to 22.8% over the porogen loading range of 0-30 wt%. In addition to XR analysis, the surface and the inner structures of films are investigated and discussed with atomic force and scanning electron microscopy images.

ORFEUS SURVEYS OF THE INTERSTELLAR MOLECULAR HYDROGEN (ORFEUS 위성을 이용한 성간 수소분자의 전천 관측)

  • Lee, Dae-Hee;Seon, Kwang-Il;Min, Kyoung-Wook
    • Publications of The Korean Astronomical Society
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    • v.20 no.1 s.24
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    • pp.11-20
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    • 2005
  • We present measurements of interstellar $H_2$ absorption lines in the continuum spectra of 54 early-type stars in the Galactic disk and halo and 3 stars in the Magellanic Clouds. The data were obtained with the Berkeley Extreme and Far-Ultraviolet Spectrometer (BEFS), part of the ORFEUS telescope, which flew on the ORFEUS-SPAS I and II space-shuttle missions in 1993 and 1996, respectively. The spectra extend from the interstellar cutoff at $912{\AA}$ to about $1200{\AA}$ with a spectral resolution of ${\sim}3000$ and statistical signal-to-noise ratios between 10 and 65. Assuming a velocity profile derived from optical observations (when available), we model the column densities N(J) of the rotational levels J = 0 through 5 for each line of sight. Our data reproduce the relationships among molecular and total hydrogen column density, fractional molecular abundance, and reddening first seen in Copernicusobservations of nearby stars (Savage et al. 1977). The results show that most of these molecular clouds have $H_2$ total column densities between $10^{15}cm^{-2}$ and $10^{21}cm^{-2}$, and kinetic temperatures from 21 K to 232 K, with average of 89 K, consistent with the result of Copernicus (Savage et al. 1977).

The Effect of Gamma Irradiation on PLGA and Release Behavior of BCNU from PLGA Wafer

  • Lee, Jin-Soo;Chae, Gang-Soo;Gilson Khang;Kim, Moon-Suk;Cho, Sun-Hang;Lee, Hai-Bang
    • Macromolecular Research
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    • v.11 no.5
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    • pp.352-356
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    • 2003
  • The objectives of this study were to investigate the influence of gamma irradiation for sterilization on poly(D,L-lactide-co-glycolide) (PLGA) with different molecular weight and the effect of gamma irradiation on the release behavior of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU, carmustine) from PLGA wafer with various irradiation doses. The effect of gamma irradiation on PLGA was evaluated by gel permeation chromatography (GPC), differential scanning calorimetry (DSC), and electron paramagnetic resonance (EPR). The weight average molecular weight (M$_{w}$) and glass transition temperature (T$_{g}$) of PLGA decreased after gamma irradiation. The extent of M$_{w}$ reduction was dependent on irradiation dose and PLGA molecular weight. Using EPR spectroscopy, we successfully detected gamma irradiation induced free radicals in PLGA. The gamma irradiation increased the release rate of BCNU from PLGA wafer at applied irradiation doses except 2.5 Mrad of irradiation dose in this study.study.

The Use of the Strain Containing Multiple Plasmids as Size Reference Plasmids (분자량측정을 위한 Reference Plasmid 보유균주의 이용)

  • Bang, Sung-Hyuk;Lee, Yoo-Chul;Seol, Sung-Yong;Cho, Dong-Taek
    • The Journal of the Korean Society for Microbiology
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    • v.22 no.3
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    • pp.267-273
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    • 1987
  • In the analysis of plasmid profile obtained by agarose gel electrophoresis, the strain harvoring multiple reference plasmids of known molecular weight were needed to estimate the size of unknown molecular weight plasmids. Six strains of E. coli isolated from clinical specimens carried multiple plasmids and these strains could be available as a reference plasmids harvoring strain. These E. coli strains showed 4 to 9 plasmids of various size ranging 2.5 to 94.3 megadalton (Mdal). The correlation coefficients of linear regression between the relative mobility and molecular weight were 0.99966 to 1.00000. Among them, E. coli KE327 from throat which contained 7 plasm ids as follows: 79 Mdal, 46 Mdal, 33 Mdal(pKY3027 C), 4.9Mdal, 3.8Mdal(pKY3027 E), 3.5Mdal, and 2.7 Mdal. Relative amount of the pKY3027 C was the smallest(7.09%) and that of the pKY3027 E was the largest (24.24%) among the plasmid fractions of E. coli KE327.

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Effect of aspect ratio on solutally buoyancy-driven convection in mercurous chloride $(Hg_2Cl_2)$ crystal growth processes

  • Kim, Geug-Tae;Lee, Kyoung-Hwan
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.16 no.4
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    • pp.149-156
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    • 2006
  • For an aspect ratio (transport length-to-width) of 5, Pr = 2.89, Le = 0.018, Pe = 2.29, Cv = 1.11, $P_B$=40 Torr, solutally buoyancy-driven convection $(Gr_s=3.03{\times}10^5)$ due to the disparity in the molecular weights of the component A $(Hg_2Cl_2)$ and B (He) is stronger than thermally buoyancy-driven convection $(Cr_t=1.66{\times}10^4)$. The crystal growth rate is decreased exponentially for $2.5\;{\leq}\;Ar\;{\leq}\;5$, with (1) the linear temperature profile and a fixed temperature difference, (2) the imposed thermal profile, a fixed crystal region and varied temperature difference. This is related to the finding that the effects of side walls tend to stabilize convection in the growth reactor. But, with the imposed thermal profile, a fixed source region and varied temperature difference, the rate is increased far $2\;{\leq}\;Ar\;{\leq}\;3$, and remains nearly unchanged for $3\;{\leq}\;Ar\;{\leq}\;5$.

Kennicutt-Schmidt law with H I velocity profile decomposition in NGC 6822

  • Park, Hye-Jin;Oh, Se-Heon;Wang, Jing;Zheng, Yun;Zhang, Hong-Xin;de Blok, W.J.G.
    • The Bulletin of The Korean Astronomical Society
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    • v.46 no.1
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    • pp.32.3-33
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    • 2021
  • We present H I gas kinematics and star formation activities of NGC 6822, a dwarf galaxy located in the Local Volume at a distance of ~ 490 kpc. We perform profile decomposition of the line-of-sight velocity profiles of the high-resolution (42.4" × 12" spatial; 1.6 km/s spectral) H I data cube taken with the Australia Telescope Compact Array (ATCA). For this, we use a new tool, the so-called BAYGAUD (BAYesian GAUssian Decompositor) which is based on Bayesian Markov Chain Monte Carlo (MCMC) techniques, allowing us to decompose a line-of-sight velocity profile into an optimal number of Gaussian components in a quantitative manner. We classify the decomposed H I gas components of NGC 6822 into bulk-narrow, bulk-broad, and non_bulk with respect to their velocity and velocity dispersion. We correlate their gas surface densities with the surface star formation rates derived using both GALEX far-ultraviolet and WISE 22 micron data to examine the impact of gas turbulence caused by stellar feedback on the Kennicutt-Schmidt (K-S) law. The bulk-narrow component that resides within r25 is likely to follow the linear extension of the Kennicutt-Schmidt (K-S) law for molecular hydrogen (H2) at the low gas surface density regime where H I is not saturated.

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Study for the Real Optical Path in the TFT-LCD 3-dimensional Simulation (TFT-LCD 3차원 시뮬레이션에서의 광 경로에 대한 고려)

  • Choi Kyoung-Uk;Kim Gee-Bum;Park Woo-Sang
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.19 no.2
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    • pp.195-199
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    • 2006
  • We report a novel simulation method to calculate optical transmission considering the real paths of optic introduced in a unit pixel of TFT-LCDs using three-dimensional molecular director simulation of the tensor model. The simulation of optical path transmission profile was carried out by calculating new permittivity considered the real paths of optic in liquid crystal cell. As a result, it was clarified that the electro-optic characteristics such as movement of disclination line, contrast ratio and transmittance profile show a large difference according to the viewing angle compared with the conventional method.

The Gene Expression Profile of LPS-stimulated Microglial Cells

  • Sohn, Sung-Hwa;Ko, Eun-Jung;Kim, Sung-Hoon;Kim, Yang-Seok;Shin, Min-Kyu;Hong, Moo-Chang;Bae, Hyun-Su
    • Molecular & Cellular Toxicology
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    • v.5 no.2
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    • pp.147-152
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    • 2009
  • This study was conducted to evaluate the inflammatory mechanisms of LPS-stimulated BV-2 microglial cells. The inflammation mechanism was evaluated in BV-2 cells with or without LPS treated using the Affymetrix microarray analysis system. The microarray analysis revealed that B cell receptor signaling pathway, cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, MAPK signaling pathway, Neuro-active ligand-receptor interaction, TLR signaling path-way, and T cell receptor signaling pathway-related genes were up-regulated in LPS stimulated BV-2 cells. Selected genes were validated using real time RTPCR. These results can help an effective therapeutic approach to alleviating the progression of neuro-in-flammatory diseases.

Data Mining for Identification of Molecular Targets in Ovarian Cancer

  • Villegas-Ruiz, Vanessa;Juarez-Mendez, Sergio
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.4
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    • pp.1691-1699
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    • 2016
  • Ovarian cancer is possibly the sixth most common malignancy worldwide, in Mexico representing the fourth leading cause of gynecological cancer death more than 70% being diagnosed at an advanced stage and the survival being very poor. Ovarian tumors are classified according to histological characteristics, epithelial ovarian cancer as the most common (~80%). We here used high-density microarrays and a systems biology approach to identify tissue-associated deregulated genes. Non-malignant ovarian tumors showed a gene expression profile associated with immune mediated inflammatory responses (28 genes), whereas malignant tumors had a gene expression profile related to cell cycle regulation (1,329 genes) and ovarian cell lines to cell cycling and metabolism (1,664 genes).