• Transactions of the Korean Society of Mechanical Engineers
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• v.18 no.2
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• pp.467-478
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• 1994

This paper deals with dynamic behaviors of a free-piston Vuilleumier heat pump system, which are characterized by stroke of each diplacer/stroke ratio, operating frequency and phase angle. Based on the Isothermal Model, basic equations of motion are derived and linearized. In particular, dependence of damping coefficients of the dynamic parameters are taken into account in the formulation, which does not bring additional difficulties in the analysis. In order to investigate effects of design conditions on the dynamic parameters are taken into account in the formulation, which does not bring additional difficulties in the analysis. In order to investigate effects of design conditions on the dynamic characteristics, calculations are performed for the prototype made by Schulz and Thomas and results are qualitatively compared with their data obtained from the analysis as well as the experiment. It appears that they made a mistake in evaluating the hysteresis loss of the gas spring in their analysis. And, the present results show a better agreement with their experimental data than those by their own analysis. Although there are some unresolved aspects such as frequency variations with respect to the mean pressure and the hot space temperature, it is expected that the present analysis may be an effective tool for prediction of dynamics of a free- pistion VM machine at the preliminary design stage.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.3
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• pp.2013-2017
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• 2013

Background: To compare the effects of two adjuvant chemotherapy regimens, anthracycline-based and cyclophosphamide, methotrexate, fluorourical (CMF) on disease free survival for breast cancer patients in the Eastern Mediterranean region and Asia. Methods: In a systematic review with a multivariate mixed model meta-analysis, the reported survival proportion at multiple time points in different studies were combined. Our data sources were studies linking the two chemotherapy regimens on an adjuvant basis with disease free survival published in English and Persian in the Eastern Mediterranean region and Asia. All survival curves were generated with Graphdigitizer software. Results: 14 retrospective cohort studies were located from electronic databases. We analyzed data for 1,086 patients who received anthracycline-based treatment and 1,109 given CMF treatment. For determination of survival proportions and time we usesb the transformation Ln (-Ln(S)) and Ln (time) to make precise estimations and then fit the model. All analyses were carried out with STATA software. Conclusions: Our findings showed a significant efficacy of anthracycline-based adjuvant therapy regarding disease free survival of breast cancer. As a limitation in this meta-analysis we used studies with different types of anthracycline-based regimens.

• Journal of Ocean Engineering and Technology
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• v.36 no.2
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• pp.83-90
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• 2022

This paper presents the minimum submergence depth of an underwater vehicle that can remove the effect of free surface on the resistance of the underwater vehicle. The total resistance of the underwater vehicle in fully submerged modes comprises only viscous pressure and friction resistances, and no wave resistance should be present, based on the free surface effect. In a model test performed in this study, the resistance is measured in the range of 2 to 10 kn (1.03-5.14 m/s) under depth conditions of 850 mm (2.6D) and 1250 mm (3.8D), respectively, and the residual resistance coefficients are compared. Subsequently, resistance analysis is performed via computational fluid dynamics (CFD) simulation to investigate the free surface effect based on various submergence depths. First, the numerical analysis results in the absence of free surface conditions and the model test results are compared to show the tendency of the resistance coefficients and the reliability of the CFD simulation results. Subsequently, numerical analysis results of submergence depth presented in a reference paper are compared with the model test results. These two sets of results confirm that the resistance increased due to the free surface effect as the high speed and depth approach the free surface. Therefore, to identify a fully submerged depth that is not affected by the free surface effect, case studies for various depths are conducted via numerical analysis, and a correlation for the fully submerged depth based on the Froude number of an underwater vehicle is derived.

• Structural Engineering and Mechanics
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• v.41 no.1
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• pp.67-81
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• 2012

Differential Quadrature Method (DQM) is a powerful method which can be used to solve numerical problems in the analysis of structural and dynamical systems. In this study the governing equation which represents the free vibration of coupled shear walls is solved using the DQM method. A one-dimensional model has been used in this study. At the end of study various examples are presented to verify the accuracy of the method.

• Journal of the Korean Society of Visualization
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• v.9 no.3
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• pp.59-64
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• 2011

In this study the change of free surface vortex is expressed through the time volume fraction using multiphase unsteady condition in sump, because in previous studies of the pump sump did not represent the behavior of the free surface vortex exactly due to the reason it was calculated using single phase and steady condition. The reliability of the computational analysis is verified through comparing experimental results with that of present numerical analysis. Homogeneous free surface model is used to apply interactions of air and water. The results show that the free surface vortex can be identified on the isotropic surface at air volume fraction 1%~5%. The vortices make an air column from the free surface to the sump intake and are created and destroyed repeatedly. The behavior of free surface vortex at numerical analysis is quite similar to experimental test. The result of vortex motion according to time, works on a cycle.

• Structural Engineering and Mechanics
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• v.28 no.6
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• pp.635-658
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• 2008

An application is presented of a modified Vlasov model to the free vibration analysis of plates resting on elastic foundations. The effects of the subsoil depth, the ratio of the plate dimensions, the ratio of the subsoil depth to the plate dimension in the longer direction, and the value of the vertical deformation parameter within the subsoil on the frequency parameters of plates on an elastic foundation are investigated. This analysis has been caried out by the aid of a computer program. The first ten frequency parameters are presented in tabular and the graphical forms to evaluate the effects of the parameters considered in this study. Then mode shapes corresponding to the first six of the frequency parameters are given in graphs. It is concluded that the effect of the subsoil depth on the frequency parameters of the plates on an elastic foundation is generally larger than those of the other parameters considered in this study.

• 한국전산유체공학회:학술대회논문집
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• 2009.04a
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• pp.315-320
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• 2009

A computational investigation is conducted on free convection from a thin plate having a surface heat source. The thermal configuration simulates the recently-proposed transparent film heater made of a single-walled carbon nanotube film on a glass substrate. The Navier-Stokes computations are carried out to study laminar free convection from the heater. Parallel numerical experiments are performed by using a simplified design analysis model which solve the conduction equation with the boundary conditions utilizing several existing correlations for convective heat transfer coefficient. Comparison leads to the most suitable boundary condition for the thermal model to evaluate the performance evaluation of a transparent thin-film heater.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2002.11b
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• pp.68-73
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• 2002

It is necessary first to understand dynamic characteristics of bus full BIW assembly for fatigue endurance analysis. FE model has been used usually for analyzing the dynamic behavior of structures. A lot of experience and effort, however, is necessary to make the credible FE model. Experimental modal analysis of structures has been performed to verify the credibility of initial FE model and to update the model. In this work, experimental modal analysis was performed to understand dynamic characteristics of bus full BIW assembly in free-free boundary condition and the result was used to verify the initial FE model. In addition, some practical techniques, which were used in this experiment, were mentioned.

• Advances in materials Research
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• v.12 no.1
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• pp.43-65
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• 2023

Free vibration analysis of power law and sigmoidal sandwich plates made up of functionally graded materials (FGMs) has been carried out using finite element based higher-order zigzag theory. The present model satisfies all-important conditions such as transverse shear stress-free conditions at the plate's top and bottom surface along with continuity condition for transverse stresses at the interface. A Nine-noded C0 finite element having eleven degrees of freedom per node is used during the study. The present model is free from the requirement of any penalty function or post-processing technique and hence is computationally efficient. The present model's effectiveness is demonstrated by comparing the present results with available results in the literature. Several new results have been proposed in the present work, which will serve as a benchmark for future works. It has been observed that the material variation law, power-law exponent, skew angle, and boundary condition of the plate widely determines the free vibration behavior of sandwich functionally graded (FG) plate.

• Journal of the Korean Magnetic Resonance Society
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• v.22 no.1
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• pp.18-25
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• 2018

Replication protein A (RPA) is an essential single-stranded DNA binding protein in DNA processing. It is known that N terminal domain of RPA70 (RPA70N) recruits various protein partners including damage-response proteins such as p53, ATRIP, Rad9, and MRE11. Although the common binding residues of RPA70N were revealed, dynamic properties of the protein are not studied yet. In this study, we measured $^{15}N$ relaxation parameters ($T_1,\;T_2$ and heteronuclear NOE) of human RPA70N and analyzed them using model-free analysis. Our data showed that the two loops near the binding site experience fast time scale motion while the binding site does not. It suggests that the protein binding surface of RPA70N is mostly rigid for minimizing entropy cost of binding and the loops can experience conformational changes.