• Title/Summary/Keyword: model-free analysis

Search Result 1,585, Processing Time 0.042 seconds

Estimation of genetic parameter for carcass traits of commercial steers in Pyeongchang (평창지역 거세출하우 자료를 이용한 유전모수 추정)

  • Dang, Chang-Gwon;Kim, Hyeong-Cheol;Jang, Sun-Sik;Lee, Jeong-Mook;Hong, Yeong-Hun;Jeon, Gi-Jun;Yeon, Seong-Heum;Kang, Hee-Seol;Yang, Bo-Suk;Hong, Seong-Koo;Lee, Jun-Heon;Lee, Seung-Hwan
    • Korean Journal of Agricultural Science
    • /
    • v.40 no.4
    • /
    • pp.339-345
    • /
    • 2013
  • The objective of this study was to establish genetic evaluation systems with carcass data collected by 68 individual farms from 2007 to 2011 in Pyeongchang area of Kangwon province. All the possible of environment effects were corrected by analysis of variance (ANOVA) to estimate more accurate genetic parameters. Heritabilities and genetic correlations were estimated from carcass data collected from Hanwoo steers(n=10,441) born in Pyeongchang region from 2005 to 2008. Traits evaluated included carcass weight (CWT), eye muscle area (EMA), back fat thickness (BF) and marbling score (MS). As for the mean value and standard deviation for carcass traits, CWT, EMA, BF and MS were 424.5, 92, 13.7 and 5.7. Parameters were estimated using a multiple trait animal model and derivative-free restricted maximum likelihood procedures. Estimated heritabilities for CWT, EMA, BF and MS were 0.30, 0.21, 0.42 and 0.42, respectively. Genetic correlation of CWT with EMA, BF and MS were estimated to 0.24, 0.36 and 0.07, respectively. Genetic correlation of EMA with BF and MS was -0.27 and 0.61, respectively.

Predicting Peer Rejection of Middle-school Students with Ordered Probit Analysis (중학생 또래따돌림('왕따')의 예측요인)

  • Lee, Sang-Gyun
    • Korean Journal of Social Welfare
    • /
    • v.37
    • /
    • pp.357-379
    • /
    • 1999
  • In recent years, the subject of peer rejection in school settings has received increased attention in the massmedia and counseling literature. This study focused on the effect of individual and environmental factors on peer rejection. Dependent variable was the number of perpetrating peer rejection and independent variables were psychological, behavioral, familial factors, exposure of peer rejection and perception about school policies. Ordered Probit model was employed because of the nature of limited dependent variable. The data were collected from 714 middle-school student in Seoul. Major findings were as follows. First of all, the adolescents who has aggression and problematic behaviors in school were more likely to participate in peer rejection. Second, negative parent-children relationships and the family structure didn't have significant effects on peer rejection. And there were not a significant effect of attitude toward academic value and academic achievement on peer rejection. Third, environmental risk factors such as negative peer relationship and the exposure to rejection had a significant increasing effect on peer rejection. But consistent school policies didn't have a significant effect. In conclusion, this study confirmed that peer rejection in school settings was affected by school environment such as negative-peer relationship, and exposure to rejection. Therefore, comprehesive and systematic intervention programs should be required to ensure that all the pupils at school have a right to learn in a safe and fear-free environment.

  • PDF

The analysis of two-lane highway traffic flows in case of the neighborhood electric vehicle involved (2차로도로에서 저속전기자동차 혼입에 따른 교통류 특성분석)

  • Jang, Keun-Woo;Jung, Sung-Hwa;Cho, Ju-Myung;Jung, Phil-Hyun
    • The Journal of The Korea Institute of Intelligent Transport Systems
    • /
    • v.10 no.5
    • /
    • pp.124-134
    • /
    • 2011
  • To make popular the NEV(Neighborhood Electric Vehicles) uses, it must be considered the supply of infrastructure and the political decision for NEV. However, the guidelines of infrastructure for NEV are not prepared. The guidelines of infrastructure for NEV should be performed in many research and case. The purpose of this study is to reveal the influence of NEV on the two-lane highway traffic flows by TWOPAS simulation model. The main items to check the influence are Average Travel speed, Percent Time Spent Following and Total Delay. The scenario were setup by traffic volume. And the NEV percentages are changed from 1% ~ 30%. The scenario 1 which traffic volume are 650veh/h and the scenario 4 which traffic volume are 2,600veh/h are less influenced by NEV, compare to scenario 2, scenario 3. Because the scenario 1 is more free to make passing other cars and Scenario 4 is fully saturated with existing traffic volumes. The urban two-lane highway which has much traffic volume and the rural two-lane highway which has little traffic volume has affinity for NEV than the other two-lane highway.

Risk Factors for Clinical Metastasis in Men Undergoing Radical Prostatectomy and Immediate Adjuvant Androgen Deprivation Therapy

  • Taguchi, Satoru;Fukuhara, Hiroshi;Kakutani, Shigenori;Takeshima, Yuta;Miyazaki, Hideyo;Suzuki, Motofumi;Fujimura, Tetsuya;Nakagawa, Tohru;Igawa, Yasuhiko;Kume, Haruki;Homma, Yukio
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.15 no.24
    • /
    • pp.10729-10733
    • /
    • 2015
  • Background: Adjuvant androgen deprivation therapy (ADT) is a treatment option for prostate cancer (PC) patients after radical prostatectomy (RP). Although it can achieve a good progression-free survival rate, some patients still develop clinical metastasis. We here investigated risk factors of clinical metastasis in post-prostatectomy patients who received immediate adjuvant ADT. Materials and Methods: We identified 197 patients with non-metastatic PC who underwent RP at our institution between 2000 and 2012, followed by adjuvant ADT. The associations of various clinicopathologic factors with clinical metastasis (primary endpoint) and cancer-specific survival (secondary endpoint) were assessed. Multivariate analysis was conducted using a Cox proportional hazards model. Median follow-up was 87 months after RP. Results: Nine (4.6%) patients developed clinical metastasis and six (3.0%) died from PC. Eight of nine metastatic patients had a pathologic Gleason score (GS) 9 and developed bone metastasis, while the remaining one had pathologic GS 7 and developed metastasis only to para-aortic lymph nodes. On multivariate analyses, pathologic GS ${\geq}9$ and regional lymph node metastasis (pN1) were independent predictors of clinical metastasis and pathologic GS ${\geq}9$ was an independent predictor of cancer-specific death. Conclusions: Pathologic GS ${\geq}9$ and pN1 were independent predictors of clinical metastasis in post-prostatectomy patients who received immediate adjuvant ADT. Furthermore, pathologic GS ${\geq}9$ was an indispensable condition for bone metastasis, which may imply that patients with GS ${\leq}8$ on adjuvant ADT are unlikely to develop bone metastasis.

Determination of Appropriate Sampling Time for Job Stress Assessment: the Salivary Chromogranin A and Cortisol in Adult Females

  • Hong, Ran-Hi;Yang, Yun-Jung;Kim, Sang-Yon;Lee, Won-Young;Hong, Yeon-Pyo
    • Journal of Preventive Medicine and Public Health
    • /
    • v.42 no.4
    • /
    • pp.231-236
    • /
    • 2009
  • Objectives : This study was conducted to determine the appropriate sampling time of the salivary stress markers, chromogranin A (CgA) and cortisol as objective indices of job stress assessment in adult females. Methods : The subjects were 20${\sim}$39-year-old women (13 office workers, 11 sales-service workers, and 11 college students) who were eligible for the study and free of acute and chronic medical conditions. Salivary CgA and cortisol levels were determined by enzyme-linked immunosorbent assay (ELISA). Saliva samples were collected (2 $m{\ell}$ each) at 7:00, 8:00, 10:30, 12:00, 17:30, and 22:30 on a typical day. Salivary CgA and cortisol levels, according to sampling time, were compared among the three groups using general linear model. The full version of the Korean Occupational Stress Scale (KOSS), which includes socioeconomic characteristics, health behavior, workrelated characteristics, and BMI, was used to access the subjects' job stress. Multiple regression analysis of the job stressors identified by the KOSS was performed on salivary CgA and cortisol levels. Results : The salivary CgA level peaked at 7:00 (time of awakening), then decreased and were maintained at a low level throughout the day, and increased slightly at 17:30. The salivary cortisol level increased steeply within the 1st hour after awakening, followed by a gradual decrease by 12:00, and was then maintained at a low level throughout the day. The salivary cortisol levels of subjects who worked ${\leq}$5 days per week and graduated from the university were significantly lower at 8:00 (p=0.006). The salivary cortisol levels of non-smokers were significantly lower at 7:00 p=0.040) and 8:00 (p=0.003) compared to smokers. There were no significant differences in salivary CgA and cortisol levels at 10:30 and 12:00 in general characteristics. The regression coefficients on salivary CgA level were significant with interpersonal conflict at 17:30 and job insecurity at 22:30. Regression coefficients on salivary cortisol level were significant with organizational system and total job stressors at 17:30. Conclusions : We suggest that the appropriate sampling times for the salivary stress markers, CgA and cortisol, are at 7:00 (time of awakening), 8:00 (1 hour after awakening), 17:30 (early evening), and 22:30 (before sleep).

Protective effects of Gastrodia elata extract by steaming time on acute gastritis (증숙 횟수에 따른 천마 추출물의 급성 위염 개선효과)

  • Lee, Ah Reum;Kwon, O Jun;Noh, Jeong Sook;Roh, Seong-Soo
    • Korean Journal of Food Science and Technology
    • /
    • v.48 no.6
    • /
    • pp.597-603
    • /
    • 2016
  • This study aimed to explore the protective effect of Gastrodia elata (GE) in an HCl/ethanol induced acute gastritis model by differing the steaming time. The samples GE1 (GE by steaming for 1 time) and GE9 (GE by steaming for 9 times), were selected based on the results of HPLC analysis, free radical scavenging activities, and total phenol and flavonoid contents. To evaluate the anti-inflammatory effect of GE, ICR mice were divided into 5 groups; normal mice (Nor), gastritic mice with distilled water (Con), gastritic mice with 100 mg/kg GE1, gastritic mice with 100 mg/kg GE9 and gastritic mice with 10 mg/kg sucralfate (SC). HCl/ethanol-induced gastric mucosal injury was markedly improved by GE9 treatment as observed during histological evaluation. The increased reactive oxygen species levels in the serum were diminished by GE9 treatment. Furthermore, peroxynitrite levels of the stomach tissue were decreased in the GE9-treated group. The analyses of stomach proteins indicated that GE9 treatment effectively reduced inflammatory cytokine levels as compared to that by GE1 treatment. These results suggest that GE9 improves health during acute gastritis.

Effect of Retailer Credibility on Attitude to Private Brand and Product Purchase Intention (유통업체 신뢰성이 유통업체 브랜드(PB)에 대한 태도 및 PB상품의 구매의도에 미치는 영향)

  • Lou, Liguo;Park, Man Seok;Koh, Joon
    • The Journal of the Korea Contents Association
    • /
    • v.15 no.11
    • /
    • pp.467-485
    • /
    • 2015
  • The market share of private brand(PB) is growing at a rapid pace. Based on the previous studies, consumers pay more attention to the extrinsic cues when they buy the PB products. This paper proposes an integrated model to examine how the retailer credibility which is one of the important extrinsic cues affects perceived quality variation, value consciousness, attitude to PB, and PB product purchase intention. Also, familiarity with PB is regarded as a moderating variable that can interact with retailer credibility. An analysis of 199 useable questionnaires found that retailer credibility has a significant impact on the attitude to PB, directly and indirectly. Further, the moderating effect of familiarity with PB was significant. For this, we interpret that when consumers are more familiar with the private brand, they tend to have few bias toward the quality of PB. These findings provide several effective strategies for the development of PB, such that retailers must improve consumer's familiarity with PB via various promotions like free samples or testing events. Academic and practical implications of the study findings and future research directions are also discussed.

Effects of Glutamine Deprivation and Serum Starvation on the Growth of Human Umbilical Vein Endothelial Cells (재대정맥 내피세포의 증식에 미치는 글루타민 및 혈청 결핍의 영향)

  • Jeong, Jin-Woo;Lee, Hye Hyeon;Park, Cheol;Kim, Wun-Jae;Choi, Yung Hyun
    • Journal of Life Science
    • /
    • v.23 no.7
    • /
    • pp.926-932
    • /
    • 2013
  • Glutamine and serum are essential for cell survival and proliferation in vitro, yet the signaling pathways that sense glutamine and serum levels in endothelial cells remain uninvestigated. In this study, we examined the effects of glutamine deprivation and serum starvation on the fate of endothelial cells using a human umbilical vein endothelial cell (HUVEC) model. Our data indicated that glutamine deprivation and serum starvation trigger a progressive reduction in cell viability through apoptosis induction in HUVECs as determined by DAPI staining and flow cytometry analysis. Although the apoptotic effects were more predominant in the glutamine deprivation condition, both apoptotic actions were associated with an increase in the Bax/Bcl-2 (or Bcl-xL) ratio, down-regulation of the inhibitor of apoptosis protein (IAP) family proteins, activation of caspase activities, and concomitant degradation of poly (ADP-ribose) polymerases. Moreover, down-regulation of the expression of Bid or up-regulation of truncated Bid (tBid) were observed in cells grown under the same conditions, indicating that glutamine deprivation and serum starvation induce the apoptosis of HUVECs through a signaling cascade involving death-receptor-mediated extrinsic pathways, as well as mitochondria-mediated intrinsic caspase pathways. However, apoptosis was not induced in cells grown in glutamine- and serum-free media when compared with cells exposed to glutamine deprivation or serum starvation alone. Taken together, our data indicate that glutamine deprivation and serum starvation suppress cell viability without apoptosis induction in HUVECs.

Thermodynamic Analysis of Phenol Adsorption by Powdered Activated Carbon (활성탄에 의한 페놀 흡착의 열역학적 연구)

  • Kim, Hwanik;Lee, Myoung-Eun;Kang, Seoktae;Chung, Jae-Woo
    • Journal of Korean Society of Environmental Engineers
    • /
    • v.35 no.3
    • /
    • pp.220-225
    • /
    • 2013
  • The adsorption characteristics of phenol by the powdered activated carbon (PAC) were investigated by series of batch experiments. The pseudo-second-order model described the adsorption kinetics adequately with correlation coefficients over 0.999, indicating chemical adsorption as the rate-limiting step. The kinetic rate constants were from 0.55 to 19.81 mg $mg^{-1}min^{-1}$. The adsorption isotherm followed the Langmuir isotherm, indicating the homogeneous mono-layer adsorption onto the surface of the adsorbent. The values of activation energy, enthalpy and entropy were 17.44 kJ $mol^{-1}$, -8.26 kJ $mol^{-1}$ and -18.94 J $mol^{-1}K^{-1}$, respectively. The Gibbs free energy was in the range of -2.89~-2.14 kJ $mol^{-1}$. The results show that the phenol adsorption is physical, spontaneous and exothermic reaction.

A Sustainability Study Based on Farm Management Value-Chain Structure (농업경영의 가치사슬 구조에 근거한 지속가능성 연구)

  • Cheong, Hoon-Hui;Kim, Sa-Gyun;Heo, Seoung-Wook
    • Journal of Agricultural Extension & Community Development
    • /
    • v.16 no.2
    • /
    • pp.363-384
    • /
    • 2009
  • This study aimed at finding directions for Korean agriculture to establish a new paradigm of sustainable development. Various problematic issues and concerns in the environment necessitate the transformation of Korea's development paradigm from unconditional growth to "Green Growth" through new policies on green value and review of various advanced researches. In this research, the environment-friendly agriculture's problems, particularly in agribusiness were analyzed. Drawing from Michael Porter's Value Chain Analysis, this research developed a value chain model in agriculture that reflects the environment and the present situations. Future directions in the agriculture sector were also discussed. Korea realized food self-sufficiency through the green revolution in the early 1970s. However, a lot of problems have also occurred, including ground and water pollution and the destruction of ecosystems as a result of the overuse of pesticides and chemical fertilizers. In the late 1970s, the growing interest on environment-friendly agriculture led to the introduction of sustainable methods and techniques. Unfortunately however, these were not innovative enough to foster environment-friendly agriculture. Thereafter, the consumers' distrust on agricultural products has worsened and concerns about health have increased. In view of this, the Ministry of Food, Agriculture, Forestry and Fisheries introduced in December 1993 a system of Quality-Certified Products for organic and pesticide-free agri-foods. Although a fundamental step toward the sustainability of the global environment, this system was not enough to promote environment-friendly agriculture. In 2008, Korea's vision is for "Low Carbon Green Growth" to move forward while also coping with climate change. But primary sectors in a typical value chain do not consider the green value of their operations nor look at production from an environmental perspective. In order to attain sustainable development, there is a need to use less resources and energy than what is presently used in Korean agricultural and value production. The typical value chain should be transformed into a "closed-loop" such that the beginning and the end of the chain are linked together. Such structure allows the flow of materials, products and even wastes among participants in the chain in a sustained cycle. This may result in a zero-waste sustainable production without destroying the ecosystem.

  • PDF