• 한국지하수토양환경학회지:지하수토양환경
• /
• 제20권7호
• /
• pp.53-60
• /
• 2015

This study suggested the new site classification system according to land use, type of contamination and contaminants. Because the present site classification system can not cover all the areas, we changed the concept of land use to more detail one and enlarged the concept of other areas to cover all the areas not defined as certain land use. In case of the present industrial area, it was merged as other areas to avoid the confusion with oil and toxic material storage tank farm area. Accident area was separated from other areas and defined as only accident area caused by the mobile storage facility. In addition to classify the sites according to the basic land use, we classify the sites again in lower level according to the type of contamination and contaminants. With this classification system, we proposed different soil sampling strategy with the consideration of the origin of contamination and the interactions between soil and contaminants. We removed the surface soil sample (0~15 cm depth) around above storage tank because it was not a effective sample to assess whether that area contaminated or not. We also proposed to take the deeper soil samples at minimum three sampling points to confirm the depth of contamination in exploratory soil survey. We also proposed to remove the one point of 15 m depth sampling because it is not effective to confirm contaminated soil depth and needs the exhausted labor and cost. Instead of doing this, we added the continuous sampling to uncontaminated subsoil. Soil sampling points and depth in detailed soil survey is determined based on the results of exploratory soil survey. Therefore, effectiveness and reinforcements of exploratory soil survey would play an important role in improving the reliability of detailed soil survey.

• 한국정보과학회논문지:데이타베이스
• /
• 제34권2호
• /
• pp.133-140
• /
• 2007

플래시 메모리는 오늘날 다양한 형태로 우리 생활의 일부를 차지하고 있다. 이동식 저장매체, 유비쿼터스 컴퓨팅 환경과 휴대전화기, MP3플레이어, 개인정보단말기(PDA) 등의 모바일 제품 등에 광범위하게 사용되고 있다. 이처럼 많은 분야에서 사용되는 주된 이유는 플래시 메모리가 저전력, 비휘발성, 고성능, 물리적 안정성, 휴대성 등의 장점을 갖기 때문이다. 더불어 최근에는 기가바이트급 플래시 메모리도 개발되어 하드디스크의 자리를 대체할 수 있는 상황에 이르렀다. 하지만, 플래시 메모리는 하드디스크와 달리 이미 데이타가 기록된 섹터에 대해 덮어쓰기가 되지 않는다는 특성을 갖고 있다. 데이타를 덮어쓰기 위해서는 해당 섹터가 포함된 블록을 지우고(소거) 쓰기 작업을 수행해야 한다. 이로 인해 플래시 메모리의 데이타 읽기/쓰기/소거에 비용이 하드 디스크와 같이 동일한 것이 아니라 각각 다르다[1][5][6]. 이러한 특성이 고려되지 않은 기존의 OS, DBMS 등과 같은 시스템 소프트웨어에서 사용되는 교체 기법은 플래시 메모리 상에서 비효율성을 가질 수 있다. 그러므로 플래시 메모리상에서는 플래시 메모리의 특성을 고려한 효율적인 버퍼 교체 기법이 필요하다. 본 논문에서는 플래시 메모리의 특성을 고려한 버퍼 페이지 교체기법을 제안하며, 제안된 기법과 기존 기법들과의 성능 평가를 수행한다. 지프분포와 실제 워크로드를 사용한 성능평가는 플래시 메모리의 특성을 고려한 버퍼 페이지 교체 기법의 필요성을 입증한다.

• Journal of Pharmaceutical Investigation
• /
• 제35권3호
• /
• pp.137-142
• /
• 2005

A rapid, selective and sensitive reversed-phase HPLC method for the determination of glipizide in human serum was validated and applied to the pharmacokinetic study of glipizide. Glipizide and internal standard, tolbutamide, were extracted from human serum by liquid-liquid extraction with benzene and analyzed on a Nova Pak $C_{18}\;60{\AA}$ column with the mobile phase of acetonitrile-potassium dihydrogen phosphate (10 mM, pH 3.5) (4:6, v/v). Detection wavelength of 275 nm and flow rate of 0.7 ml/min were fixed for the study. The assay robustness for the changes of mobile phase pH, organic solvent content, and flow rate was confirmed by $3^3$ factorial design using a fixed glipizide concentration (500 ng/ ml) with respect to its peak area and retention time. And also, the ruggedness of this method was investigated at three different laboratories using same quality control (QC) samples. This method showed linear response over the concentration range of 10-1000 ng/ml with correlation coefficient greater than 0.999. The lower limit of quantitation using 0.5 ml of serum was 10.0 ng/ml, which was sensitive enough for pharmacokinetic studies. The overall accuracy of the quality control samples ranged from 82.6 to 105.0% for glipizide with overall precision (% C.V.) being 1.13-13.20%. The percent recovery for human serum was in the range of 85.2 93.5%. Stability studies showed that glipizide was stable during storage, or during the assay procedure in human serum. The peak area and retention time of glipizide were not significantly affected by the changes of mobile phase pH, organic solvent content, and flow rate under the conditions studied. This method showed good ruggedness (within 15% C.V.) and was successfully used for the analysis of glipizide in human serum samples for the pharmacokinetic studies at three different laboratories, demonstrating the suitability of the method.

• Journal of Pharmaceutical Investigation
• /
• 제35권4호
• /
• pp.265-271
• /
• 2005

A rapid, selective and sensitive reversed-phase HPLC method for the determination of etodolac in human serum was developed, validated, and applied to the pharmacokinetic study of etodolac. Etodolac and internal standard, ibuprofen were extracted from human serum by liquid-liquid extraction with hexane/isopropanol (95:5, v/v) and analyzed on a Luna C18(2) column with the mobile phase of 1% aqueous acetic acid-acetonitrile (4:6, v/v). Detection wavelength of 227 nm and flow rate of 1.0 mL/min were fixed for the study. The assay robustness for the changes of mobile phase pH, organic solvent content, and flow rate was confirmed by $3^3$ factorial design using a fixed etodolac concentration $(1\;{\mu}g/mL)$ with respect to its peak area and retention time. And also, the ruggedness of this method was investigated at three different laboratories using same quality control (QC) samples. This method showed linear response over the concentration range of $0.05-40\;{\mu}g/mL$ with correlation coefficients greater than 0.999. The lower limit of quantification using 0.5 mL of serum was 0.05 ${\mu}g/mL$, which was sensitive enough for pharmacokinetic studies. The overall accuracy of the quality control samples ranged from 92.00 to 110.00% for etodolac with overall precision (% C.V.) being 1.08-10.11%. The percent recovery for human serum was in the range of 76.73-115.30%. Stability studies showed that etodolac was stable during storage, or during the assay procedure in human serum. The peak area and retention time of etodolac were not significantly affected by the changes of mobile phase pH, organic solvent content, and flow rate under the conditions studied. This method showed good ruggedness (within 15% C.V.) and was successfully used for the analysis of etodolac in human serum samples for the pharmacokinetic studies of orally administered Lodin XL tablet (400 mg as etodolac) at three different laboratories, demonstrating the suitability of the method.

• Journal of Pharmaceutical Investigation
• /
• 제35권6호
• /
• pp.423-429
• /
• 2005

A selective and sensitive reversed-phase HPLC method for the determination of fenoprofen in human serum was developed, validated, and applied to the pharmacokinetic study of fenoprofen calcium. Fenoprofen and internal standard, ketoprofen, were extracted from human serum by liquid-liquid extraction with diethyl ether and analyzed on a Luna C18(2) column with the mobile phase of acetonitrile-3 mM potassium dihydrogen phosphate (32:68, v/v, adjusted to pH 6.6 with phosphoric acid). Detection wavelength of 272 nm and flow rate of 0.25 mL/min were fixed for the study. The assay robustness for the changes of mobile phase pH, organic solvent content, and flow rate was confirmed by $3^{3}$ factorial design using a fixed fenoprofen concentration $(2\;{\mu}g/mL)$ with respect to its peak area and retention time. And also, the ruggedness of this method was investigated at three different laboratories using same quality control (QC) samples. This method showed linear response over the concentration range of $0.05-100\;{\mu}g/mL$ with correlation coefficients greater than 0.999. The lower limit of quantification using 1 mL of serum was $0.05\;{\mu}g/mL$, which was sensitive enough for pharmacokinetic studies. The overall accuracy of the quality control samples ranged from 92.27 to 109.20% for fenoprofen with overall precision (% C.V.) being 5.51-11.71 %. The relative mean recovery of fenoprofen for human serum was 81.7%. Stability (freeze-thaw, short and long-term) studies showed that fenoprofen was not stable during storage. But, extracted serum sample and stock solution were allowed to stand at ambient temperature for 12 hr prior to injection without affecting the quantification. The peak area and retention time of fenoprofen were not significantly affected by the changes of mobile phase pH, organic solvent content, and flow rate under the conditions studied. This method showed good ruggedness (within 15% C.V.) and was successfully used for the analysis of fenoprofen in human serum samples for the pharmacokinetic studies of orally administered Fenopron tablet (600 mg as fenoprofen) at three different laboratories, demonstrating the suitability of the method.

• Journal of Pharmaceutical Investigation
• /
• 제36권1호
• /
• pp.45-51
• /
• 2006

A rapid, selective and sensitive reversed-phase HPLC method for the determination of dipyridamole in human serum was developed, validated, and applied to the pharmacokinetic study of dipyridamole. Dipyridamole and internal standard, loxapine, were extracted from human serum by liquid-liquid extraction with diethyl ether and analyzed on a Nova Pak $C_{I8}$ column with the mobile phase of 40 mM ammonium acetate:methanol:acetonitrile (35:35:30)(v/v/v, pH 7.8). Detection wavelength of 280 nm and flow rate of 1.0 mL/min were fixed for the study. The assay robustness for the changes of mobile phase pH, organic solvent content, and flow rate was confirmed by $3^3$ factorial design using a fixed dipyridamole concentration (50 ng/mL) with respect to its peak area and retention time. And also, the ruggedness of this method was investigated at three different laboratories using same quality control (QC) samples. This method showed linear response over the concentration range of 2-2000 ng/mL with correlation coefficients greater than 0.999. The lower limit of quantification using 0.5 mL of serum was 2 ng/mL, which was sensitive enough for pharmacokinetic studies of dipyridamole. The overall accuracy of the quality control samples ranged from 103.94 to 105.86% for dipyridamole with overall precision (% C.V.) being 4.60-11.49%. The relative mean recovery of dipyridamole for human serum was 97.64%. Stability studies showed that dipyridamole was stable during storage, or during the assay procedure in human serum. The peak area and retention time of dipyridamole were not significantly affected by the changes of mobile phase pH, organic solvent content, and flow rate under the conditions studied. This method showed good ruggedness (within 15% C.V.) and was successfully used for the analysis of dipyridamole in human serum samples for the pharmacokinetic studies of orally administered Dimor tablet (75 mg as dipyridamole) at three different laboratories, demonstrating the suitability of the method.

• 한국정보통신학회:학술대회논문집
• /
• 한국해양정보통신학회 2005년도 춘계종합학술대회
• /
• pp.171-174
• /
• 2005

해양 레저 산업의 발달과 레저문화의 수요가 급증함에 따라 해양 안전 및 관련 정보를 제공하는 서비스에 대한 욕구가 증대하고 있다. 개인휴대단말기는 그 성능이 향상되어 복합 단말기로 진화하였고 그로인해 단순 통신 기능만이 아닌 멀티미디어 정보의 수용 및 표현이 가능해졌다. 국내 무선인터넷은 서로 다른 플랫폼을 사용하여 개발자 및 콘텐츠 제공자(CP; Contents Provider)에게 개발 부담을 주어 무선 인터넷 활성화의 저해 요인이 되어왔다. 그러나 최근 무선 인터넷 표준 플랫폼인 WIPI(Wireless Internet Platform for Interoperability)의 사용으로 무선 응용 프로그램의 상호 운용이 가능해 졌고 하드웨어에 대한 독립성 또한 보장할 수 있게 되었다. WIPI 기반의 휴대 단말기 상에 디지털화된 전자해도의 지리정보와 해양 레저를 위한 각종 정보를 제공하는 다운로드 형태의 콘텐츠를 개발하는 프로젝트의 일환으로 전자해도 및 부가 정보 DB를 구축하여 요구되는 콘텐츠를 제공하는 서버(CPS; Contents Provider Server)가 필요하다. 본 논문에서는 수요자가 개인휴대단말기를 통해 필요한 정보를 요구했을 때 CPS가 실시간으로 정보를 제공할 수 있도록 요구정보를 데이터베이스화하는 웹 탐색 에이전트를 설계하여 각종 웹상에서 시시각각 변화하는 정보들을 실시간으로 파싱하여 데이터베이스화시키는 에이전트 컴포넌트를 개발하고자 한다.

• 디지털융복합연구
• /
• 제11권12호
• /
• pp.381-386
• /
• 2013

안드로이드 플랫폼에서의 새로운 변종 악성코드가 기하급수적으로 증가함에 따라 보다 빠르고 능동적인 대처방안이 필요하다. 본 연구에서는 안드로이드 플랫폼에 High-Interaction 클라이언트 허니팟을 적용하였다. 시스템 적용방안을 위하여 전체 흐름을 설계하고 각 세부모듈의 기능을 분석하여 안드로이드 플랫폼에 최적화 하였다. 제안하는 시스템은 기존 PC 환경의 High-Interaction 클라이언트 허니팟의 장점을 모두 갖추고 있으며 관리 서버와 저장 서버를 분리하여 보다 유연하고 확장된 형태로 설계되었다.

• 플랜트 저널
• /
• 제16권3호
• /
• pp.37-41
• /
• 2020

최근 노후화된 LNG선박의 증가, 선박가격 하락으로 중고 LNG선 재활용 가능성이 증대되고 있다.또한 노후발전소 대체관련 Needs가 늘고 있으며 가스생산량 증가 및 친환경 연료가 각광받고 있어 가스 발전플랜트 매력도도 상승하고 있다. 이에 본 연구에서는 중고 LNG선을 개조하여 LNG저장 및 발전플랜트 기능을 갖추게 하고 이밖에 재기화기능,벙커링 기능을 갖춘 복합기능 플랜트에 대한 기획연구를 수행하였다.이를 통해 노후 화력발전 중단,원전해체 등으로 인한 에너지 공백을 대체하고 국가 위기사태에 이동형 발전 플랜트를 긴급으로 투입가능해지며 대북 경협 등 정책에 새로운 대안으로 활용할 수 있다.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• 제5권4호
• /
• pp.703-719
• /
• 2011

In multi-user wireless communication systems, adaptive modulation and scheduling are promising techniques for increasing the system throughput. However, a mass of wireless recourse will be occupied and spectrum efficiency will be decreased to feedback channel quality indication (CQI) of all users in every subcarrier or chunk for adaptive orthogonal frequency division multiplexing (OFDM) systems. Thus numerous limited feedback schemes are proposed to reduce the system overhead. The recently proposed compressive sensing (CS) theory provides a new framework to jointly measure and compress signals that allows less sampling and storage resources than traditional approaches based on Nyquist sampling. In this paper, we proposed two novel CQI feedback schemes based on general CS and subspace CS, respectively, both of which could be used in a wireless OFDM system. The feedback rate with subspace CS is greatly decreased by exploiting the subspace information of the underlying signal. Simulation results show the effectiveness of the proposed methods, with the same feedback rate, the throughputs with subspace CS outperform the discrete cosine transform (DCT) based method which is usually employed, and the throughputs with general CS outperform DCT when the feedback rate is larger than 0.13 bits/subcarrier.