• The Korean Journal of Physiology and Pharmacology
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• v.25 no.1
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• pp.15-26
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• 2021

Peptides are short chain of amino acids linked by peptide bonds. They are widely used as effective and biocompatible active ingredients in cosmetic industry. In this study, we developed novel peptide mixture and identified its anti-pigmentation effect on melanocytes and keratinocytes. Our results revealed that peptide mixture inhibited melanosome biogenesis through the regulation of microphthalmia-associated transcription factor, a key factor of melanogenesis in melanocytes. And we observed that peptide mixture inhibited melanosome uptake through the reduction of protease-activated receptor 2, a phagocytosis-related receptor in keratinocytes. Furthermore, peptide mixture activated autophagy system resulting in degradation of transferred melanosomes in keratinocytes. The anti-pigmentation effect of multi-targeting peptide mixture was assessed in a human skin equivalent model (MelanoDerm). Melanin contents in epidermal layer were significantly decreased by topical treatment of peptide mixture, suggesting that it can be applied as a novel cosmetics material having a whitening function.

• Proceedings of the Korean Institute of Building Construction Conference
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• v.y2004m10
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• pp.51-54
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• 2004

This paper investigated the results of mixture proportion and compressive strength of concrete incorporating mineral admixtures. W/B and contents of mineral admixtures were selected as test parameters. According to test results, use of mineral admixtures resulted in a reduction of fluidity and air contents caused by increased fine particles and absorption effect of FA on reduction of AE agent. Thus, increase of SP and AE agent was needed to maintain the same fluidity and air content as plain concrete. At early stage, use of CKD was beneficial to the compressive strength while at 28days. incorporation of FA and BS had favorable effect on the compressive strength.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2009.11a
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• pp.101-105
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• 2009

The purpose of this study is to reduce autogenous shrinkage of high-strength concrete. Previous studies were investigated to measure the effects of reductions to autogenous shrinkage when applying bean oil to concrete. The results of the study showed that as the mixture rate of BO increased, fluidity decreased and air quantity decreased slightly. In early age, compressed strength increased compared to Plain while decreased in long-term age. As an autogenous shrinkage characteristic, reduction effect increased according to increase in mixture rate. When mixture rate is 1%, approximately 30% decreased compared to Plain in BO. At 2%, BO decreased by about 32%. In addition, in the case of BO, autogenous shrinkage was shown to decrease compared to expansive additive and shrinkage-reducing agent.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.13 no.3
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• pp.194-199
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• 2001

The turbulent flow resistance of water solution with polymer is reduced as compared with that of pure water. This effects is named th drag reduction and offers the significant reduction of the pumping power and the energy consumption. But the intense shear forces and the high temperature experienced by the polymer solution when passing through the pipes cause the degradation a loss of drag reduction effectiveness. Especially, the degradation behavior is found to be strongly dependent on temperature. This mechanical and thermal degradation can be avoided by adding materials such as surfactant to the polymer solution, which enhance the bonding force between molecules. In the present study, Copolymer and SDS were utilized and they were mixed in 10 different mixture ratios, while total concentration was fixed as 100wppm. Degradation of Copolymer-SDS mixture solutions was investigated experimentally in closed loop at the temperature of $10^{\circ}C\; and\; 80^{\circ}C$ with various flow average velocities of 1.5 m/sec, 3.0m/sec, and 4.5m/sec. Degradation characteristics of polymer solution without surfactant show a radical loss of drag reduction effectiveness at high temperature. Degradation alleviation ability of surfactant is especially effective at high temperature. Consequently, this results show that the addition of surfactant to the polymer solution can control unfavorable degradation phenomena for high temperature systems.

• Journal of Korean Society of Water and Wastewater
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• v.19 no.5
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• pp.639-646
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• 2005

In this research, we tried to develop the application method to water management and treatment using toxicity test method. When we measure the toxicity of environmental samples, we have to decide whether we take some countermeasures to reduce the toxicity or not. The first issue is how to set these action levels in each bioassays. A new idea was attempted to authorize indirect approach of each bioassays through the response characteristics against mixture of chemicals in water quality standard. The significant response in the cell-growth-inhibition bioassay was detected for standards-mixture(STDs). For acute toxicity assay, STDs-based implicit correlation between risks to humans and bioassay data showed a rational approach to set action levels in practical management. A simple model was proposed to describe and predict the changes in the total toxicity based on the concentrations of toxic-controlling chemicals during the ozonation of landfill leachates. On the basis of this simple model, toxicity reduction was predicted for pre-aggregation treatment before ozonation and ozone concentration during the ozonation. The method proposed in this study would be useful in optimizing water treatment processes and their running conditions in terms of the toxicity reduction efficacy.

• Journal of the Korean Recycled Construction Resources Institute
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• v.9 no.4
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• pp.594-601
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• 2021

In order to expanding of the use of steel slag, a by-product of steel industry, as a road paving construction material, this present study confirmed the possibility of the rust formation of steel slag aggregate and evaluated the durability performance and the noise reduction characteristics of asphalt concrete mixture. As a result of conducting the rust formation test of aggregate, no rust was observed in both aggregate, so it is judged that the possibility of rust formation in the actual road water environment is very low. As a result of performing the moisture resistance test, all mixtures showed a tensile strength ratio exceeding 85%, satisfied the standard as asphalt mixture. In addition, the sound absorption coefficient of the steel slag aggregate mixture was measured to be higher than that of the general aggregate mixture. Accordingly, it is speculated th at th e steel slag aggregate mixture can more effectively respond to road noise reduction than the general mixture.

• Bulletin of the Korean Chemical Society
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• v.9 no.5
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• pp.322-324
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• 1988

Selective reduction of aldoximes and ketoximes with lithium borohydride in tetrahydrofuran was investigated. Thus, aldoximes and cyclic ketoximes such as hexanaldoxime, heptanaldoxime, cyclopentanone oxime and cyclohexanone oxime were reduced smoothly to the corresponding N-monosubstituted hydroxylamines at room temperature in 65-93% yield. The reduction of alicyclic ketoxime was very slow, requiring somewhat high reaction temperature ($65^{\circ}C$) for the complete reduction to give the hydroxnylamines. The reduction of aromatic oximes such as benzaldoxime and acetophenone oxime was very sluggish, giving a mixture of the corresponding hydroxylamines and amines at $65^{\circ}C$.

• Transactions of the Korean Society of Automotive Engineers
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• v.6 no.2
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• pp.32-42
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• 1998

Lean burn gasoline engine is recognized as a promising way to meet better fuel economy. Lean burn engine is classified into port injection and direct injection(DI), DI is more active technique for improving fuel economy with ultra-lean operation, Nowadays, port injected lean burn engine has been produced by many Japan maker. Also, DI engine is also possible for production owing to improvement in control technique of spray, flow air fuel ratio. DI engine uses either homogeneous stoichiometric mixture or stratified mixture by controlling injection timing to be early or late respectively. HM(homogeneous mixture) is worse than SM(stratified mixture) in view of ultra-lean operation in partical load and Nox reducion by using EGR control. But, HM has advanteges in cold starting and emission reduction during transient operation, This paper describes experimental variables and bench test results of HM GDI engine.

• Journal of Environmental Science International
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• v.10 no.4
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• pp.311-314
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• 2001

The asphalt mixture with CRM(Crumb Rubber Modifier) is known to show a better performance in resisting thermal cracking, fatigue cracking and rutting compared with the conventional mixture. The laboratory tests on the physical characteristics of indirect tensile strength, density, flow and Marshall value of the CRM asphalt were conducted. The test results show that CRM asphalt has better physical characteristics than that of conventional asphalts. And the analysis on the noise reduction effect, penetration capacity from the field test on the national road in Haksan of Chungbuk, and recycling of tire waste were conducted. From this study, the results show that 1% CRM asphalt has higher the noise reduction effect and penetration capacity that those of conventional asphalts. And, optimal contents of crumb rubber modifier in the asphalt binder is one percent. In this case, crumb rubber modifier were used 10 kg to make the asphalt binder of one cubic meter. So it was named as Eco-asphalt.

• Journal of the Korean Chemical Society
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• v.38 no.5
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• pp.397-403
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• 1994

An activated catalyst prepared from a mixture of nickel nitrate hexahydrate with zinc in dry ethanol under reflux showed exceptional catalytic activity for the reduction of nitroarenes to the corresponding azoxy compounds exclusively in the presence of hydrazine monohydrate. However, when nickel nitrate hexahydrate was replaced by nickel chloride dihydrate with zinc, only the aminoarenes were formed in high yields. With unactivated catalyst, the reduction reaction from a mixture of nitroarenes, nickel nitrate or chloride, excess zinc and hydrazine monohydrate gave the corresponding azo, azoxy and amino compounds in much lower yields.