• Title/Summary/Keyword: mixture 모델

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Analysis of Nitrosation Inhibition and Antioxidant Effect by Phyto-Extract Mixture (식물추출 혼합제재인 phyto-extract mixture의 니트로세이션 억제능과 항산화능 분석)

  • Kim, Ji-Hoon;Shin, Mi-Jung;Cho, Hee-Jae;Lee, Sang-Won;Jeong, Jong-Moon
    • Korean Journal of Food Science and Technology
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    • v.33 no.6
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    • pp.656-663
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    • 2001
  • The most representative nitrosamine derived from nicotine, nitrosamine-4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone(NNK), has been reported to cause lung cancer in A/J mice. It has been also demonstrated that NNK-induced lung tumorigenesis involves $O^6-methylguanine(O^6MeG)$ formation, leading to $GC\;{\rightarrow}\;AT$ transitional mispairing during DNA replication. Our in vitro experiment, modified from the method of DBA assay, examined the ability of phyto-extract mixture to inhibit the metabolism of nicotine to nitrosamines. The production of nitromorpholine from morpholine was inhibited about 75% at the concentration of 20 mg/mL of phyto-extract mixture, which was lower than vitamine C and green tea powder. NNK, which is a pro-carcinogen in laboratory animals, is hydroxylated primarily in liver and lung by CYP 1A2, 2A6 and 3A4. A critical phase. of NNK activation is its change to an unstable metabolite methyl-diazohydroxide via CYP-mediated ${\alpha}-hydroxylation$; and then it provides a methyl group to the DNA to form DNA adducts which can easily induce mutations. $Aroclor^R$ 1254 was used to induce CYPs in the liver of a Sprague-Dawley rat. The ability of various test samples to inhibit CYPs that participate in NNK activation was evaluated, following the removal of the liver from the rat. Microsomal CYPlA2 catalyzing the conversion of NNK into strong carcinogenic chemicals was inhibited more efficiently by phyto-extract mixture than green tea powder. These results indicate that phyto-extract mixture can be used to reduce $O^6MeG$ DNA adducts for chemoprevention.

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Estimation of Thermodynamic/Transport Properties of Kerosene using a 3-Species Surrogate Mixture (3-화학종 대체 혼합물을 이용한 케로신의 열역학적·전달 상태량 예측)

  • Joh, Miok;Kim, Seong-Ku;Choi, Hwan-Seok
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.41 no.11
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    • pp.874-882
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    • 2013
  • Kerosene(Jet A-1), one of the propellants for each stage's engine of the Korea Space Launch Vehicle-II(KSLV-II), functions as coolant at the same time as it flows inside the cooling jacket of the combustion chambers and is injected through the film cooling holes. A physical surrogate mixture model to reproduce the thermophysical characteristics of Jet A-1 has been selected and the thermodynamic/transport properties of the model fuel under high pressure including supercritical conditions have been estimated using SUPERTRAPP(NIST SRD4). Comparisons with the measured properties suggest that proposed database can be used to extract properties of Jet A-1 for conjugate heat transfer analysis of liquid propellant rocket engine thrust chambers. Predicted combustion/cooling performance of regeneratively cooled thrust chambers shall be validated through comparisons with upcoming firing test results.

Image Histogram Equalization Based on Gaussian Mixture Model (가우시안 혼합 모델 기반의 영상 히스토그램 평활화)

  • Jun, Mi-Jin;Lee, Joon-Jae
    • Journal of Korea Multimedia Society
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    • v.15 no.6
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    • pp.748-760
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    • 2012
  • In case brightness distribution is concentrated in a region, it is difficult to classify the image features. To solve this problem, we apply global histogram equalization and local histogram equalization to images. In case of global histogram equalization, it can be too bright or dark because it doesn't consider the density of brightness distribution. Thus, it is difficult to enhance the local contrast in the images. In case of local histogram equalization, it can produce unexpected blocks in the images. In order to enhance the contrast in the images, this paper proposes a local histogram equalization based on the Gaussian Mixture Models(GMMs) in regions of histogram. Mean and variance parameters in each regions is updated EM-algorithm repeatedly and then ranges of equalization on each regions. The experimental results performed with image of various contrasts show that the proposed algorithm is better than the global histogram equalization.

Natural Scene Text Binarization using Tensor Voting and Markov Random Field (텐서보팅과 마르코프 랜덤 필드를 이용한 자연 영상의 텍스트 이진화)

  • Choi, Hyun Su;Lee, Guee Sang
    • Smart Media Journal
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    • v.4 no.4
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    • pp.18-23
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    • 2015
  • In this paper, we propose a method for detecting the number of clusters. This method can improve the performance of a gaussian mixture model function in conventional markov random field method by using the tensor voting. The key point of the proposed method is that extracts the number of the center through the continuity of saliency map of the input data of the tensor voting token. At first, we separate the foreground and background region candidate in a given natural images. After that, we extract the appropriate cluster number for each separate candidate regions by applying the tensor voting. We can make accurate modeling a gaussian mixture model by using a detected number of cluster. We can return the result of natural binary text image by calculating the unary term and the pairwise term of markov random field. After the experiment, we can confirm that the proposed method returns the optimal cluster number and text binarization results are improved.

Unmanned Enforcement System for Illegal Parking and Stopping Vehicle using Adaptive Gaussian Mixture Model (적응적 가우시안 혼합 모델을 이용한 불법주정차 무인단속시스템)

  • Youm, Sungkwan;Shin, Seong-Yoon;Shin, Kwang-Seong;Pak, Sang-Hyon
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.25 no.3
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    • pp.396-402
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    • 2021
  • As the world is trying to establish smart city, unmanned vehicle control systems are being widely used. This paper writes about an unmanned parking control system that uses an adaptive background image modeling method, suggesting the method of updating the background image, modeled with an adaptive Gaussian mixture model, in both global and local way according to the moving object. Specifically, this paper focuses on suggesting two methods; a method of minimizing the influence of a moving object on a background image and a method of accurately updating the background image by quickly removing afterimages of moving objects within the area of interest to be monitored. In this paper, through the implementation of the unmanned vehicle control system, we proved that the proposed system can quickly and accurately distinguish both moving and static objects such as vehicles from the background image.

Improving A Text Independent Speaker Identification System By Frame Level Likelihood Normalization (프레임단위유사도정규화를 이용한 문맥독립화자식별시스템의 성능 향상)

  • 김민정;석수영;정현열;정호열
    • Proceedings of the IEEK Conference
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    • 2001.09a
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    • pp.487-490
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    • 2001
  • 본 논문에서는 기존의 Caussian Mixture Model을 이용한 실시간문맥독립화자인식시스템의 성능을 향상시키기 위하여 화자검증시스템에서 좋은 결과를 나타내는 유사도정규화 ( Likelihood Normalization )방법을 화자식별시스템에 적용하여 시스템을 구현하였으며, 인식실험한 결과에 대해 보고한다. 시스템은 화자모델생성단과 화자식별단으로 구성하였으며, 화자모델생성단에서는, 화자발성의 음향학적 특징을 잘 표현할 수 있는 GMM(Gaussian Mixture Model)을 이용하여 화자모델을 작성하였으며. GMM의 파라미터를 최적화하기 위하여 MLE(Maximum Likelihood Estimation)방법을 사용하였다. 화자식별단에서는 학습된 데이터와 테스트용 데이터로부터 ML(Maximum Likelihood)을 이용하여 프레임단위로 유사도를 계산하였다. 계산된 유사도는 유사도 정규화 과정을 거쳐 스코어( SC)로 표현하였으며, 가장 높은 스코어를 가지는 화자를 인식화자로 결정한다. 화자인식에서 발성의 종류로는 문맥독립 문장을 사용하였다. 인식실험을 위해서는 ETRI445 DB와 KLE452 DB를 사용하였으며. 특징파라미터로서는 켑스트럼계수 및 회귀계수값만을 사용하였다. 인식실험에서는 등록화자의 수를 달리하여 일반적인 화자식별방법과 프레임단위유사도정규화방법으로 각각 인식실험을 하였다. 인식실험결과, 프레임단위유사도정규화방법이 인식화자수가 많아지는 경우에 일반적인 방법보다 향상된 인식률을 얻을수 있었다.

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A Lattice Model for Intra-molecular and Inter-molecular Association in Mixture containing Surfactants (계면활성제를 함유한 혼합물에서 내외부 분자회합을 위한 격자모델)

  • Shin, Moon-Sam
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.11 no.5
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    • pp.1768-1772
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    • 2010
  • Intra-molecular association is an important contribution to the overall hydrogen bonding in surfactant systems, especially in systems of colloidal and biological interest. Amphiphile systems, especially micelle and microemulsion systems, showed highly non-ideal behavior due to the intermolecular association and intra-molecular association. The objective of this research is to present a lattice fluid equation of state that combines the quasi-chemical nonrandom lattice fluid model with modified Veytsman statistics for intra + inter molecular association to calculate phase behavior for mixture containing surfactant systems. The lattice model could describe the literature data well for alkane and surfactant systems.

Mixture distribution based nonstationary frequency model using climate variables (기후 변수를 이용한 혼합분포 기반 비정상성 빈도 모델)

  • Choi, Hong-Geun;Kim, Jang-Gyeong;Kwon, Hyun-Han
    • Proceedings of the Korea Water Resources Association Conference
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    • 2019.05a
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    • pp.338-338
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    • 2019
  • 설계강우량 산정시, 일반적으로 극치자료를 활용하여 정상성 가정하에 빈도해석을 수행하고 있다. 그러나 종종 정상성으로 가정했던 기존 극치강우자료가 정상성 빈도해석 모형에서 효과적으로 모델링되지 않는 비정상성 특성을 나타내고 있다. 또한, 대부분의 극치강우 분포는 해마다 다른 규모로 발생하는 홍수와 태풍 등의 강우요인으로 인해 두 개의 첨두를 갖는 혼합분포 형태를 보인다. 이에 본 연구에서는 혼합분포 기반 비정상성 빈도모델(mixture distribution based nonstationary frequency model, MDNF)을 제시하였다. 제안된 모형의 입력자료로 기후변수(e.g. SSTs and SLPs)를 사용하여 두 개의 분포형으로 구성되는 극치강우의 혼합비(mixing ratio)에 대한 영향을 분석하였으며, 극치강우 패턴이 특정 기후변수의 영향을 받는 것을 확인하였다. 최종적으로 Bayesian 기법을 MDNF 모형에 연계하여 각 첨두에 해당하는 분포형의 매개변수들에 대한 불확실성 구간을 정량적으로 제시하였다. 본 연구를 통해 강우 패턴의 변동은 설계 강우량 추정에 영향을 미치며, 특정 기후변수와 강우 패턴이 상관성을 가지는 것을 확인함으로써 합리적인 설계 강우량 산정을 위한 중요한 근거를 제공할 것으로 사료된다.

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Energy Ratio Factor and Phase Angle Based Fatigue Prediction Model for Flexible Pavements

  • Kim, Nak-Seok
    • Journal of the Korean Society of Hazard Mitigation
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    • v.11 no.2
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    • pp.75-80
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    • 2011
  • The main objective of this research is to develop fatigue prediction model for flexible pavements using energy ratio factor and phase angle. The two parameters are considered as fundamental properties of time and temperature dependent viscoelastic asphalt concrete materials. The energy ratio factor is defined as the ratio of the pseudo-total cumulative dissipated energy to the cumulative dissipated energy to failure during the test. The phase angle between the stress and strain ware signals stems from the intrinsic the dependent asphalt mixture behavior. The phase angle was computed and the relationship between the initial mixture stiffness and the initial phase angle is presented. As a result, fatigue prediction model for flexible pavements was proposed using intrinsic properties of viscoelastic asphalt concrete materials.