• 제목/요약/키워드: minimal requirement

검색결과 71건 처리시간 0.022초

Salmonella typhi의 시스테인 영양요구성에 관여하는 유전자의 동정 및 특성 연구 (Identification and Characterization of Genes Involved in Cysteine Auxotrophy in Salmonella typhi)

  • 이상호;김삼웅;유종언;유아영;김영희;오정일;백창호;강호영
    • 생명과학회지
    • /
    • 제18권11호
    • /
    • pp.1507-1512
    • /
    • 2008
  • 오랜 기간 동안의 연구에도 불구하고 사람에 특이적으로 장티푸스를 유발하는 S. typhi는 실험동물을 대상으로 하는 감염모델이 확립되어 있지 않기 때문에 S. typhi의 병원성 유발기작에 관한 정보는 부족하다. S. typhi Ty2 균주는 최소배지에서 시스테인의 영양요구성을 지닌다. 본 연구에서는 시스테인 영양요구성이, S. typhi Ty2 균주가 실험동물에서 균체형성을 하는데 어떤 영향을 미치는지를 조사하기 위해 시스테인 영양요구성을 상보할 수 있는 유전자를 찾고자 하였다. S. typhimurium의 genomic library로 형질전환된 S. typhi 균들 중 시스테인을 함유하지 않은 최소배지에서 생육을 하는 3개의 형질전환 균주를 선별하였으며, 이들 중 2개는 S. typhi의 시스테인 영양요구성을 아주 약하게 상보하였고 하나는 명확하게 시스테인의 영양요구성을 상보하였다. 이 클론에 포함되어져 있는 3개의 ORF의 시스테인 영양요구성을 분석한 결과, STM1490을 가진 클론이 S. typhi의 시스테인 영양요구성을 상보하였다. 비록 S. typhi에도 STM1490에 해당하는 유전자가 존재하지만 S. typhimurium의 STM1490에 해당하는 ORF와 비교하였을 때 2개의 아미노산 잔기가 서로 달랐다. 이들의 차이가 시스테인 영양요구성을 보이는 것은 아닌지 확인하기 위해 Overlapping PCR을 통해 S. typhimurium의 STM1490 아미노산(H229Y, C246W)을 치환하였다. 아미노산을 바꾼 돌연변이체도 역시 시스테인 영양요구성을 상보할 수 있어서 아미노산의 차이는 아닌 것을 확인되었으므로 그 외의 다른 인자들이 영양요구성에 관여하는 것으로 추정되었고 후속연구에서 그인자를 찾을 수 있을 것으로 생각된다.

Optimal Power Control Strategy for Wind Farm with Energy Storage System

  • Nguyen, Cong-Long;Lee, Hong-Hee
    • Journal of Electrical Engineering and Technology
    • /
    • 제12권2호
    • /
    • pp.726-737
    • /
    • 2017
  • The use of energy storage systems (ESSs) has become a feasible solution to solve the wind power intermittency issue. However, the use of ESSs increases the system cost significantly. In this paper, an optimal power flow control scheme to minimize the ESS capacity is proposed by using the zero-phase delay low-pass filter which can eliminate the phase delay between the dispatch power and the wind power. In addition, the filter time constant is optimized at the beginning of each dispatching interval to ensure the fluctuation mitigation requirement imposed by the grid code with a minimal ESS capacity. And also, a short-term power dispatch control algorithm is developed suitable for the proposed power dispatch based on the zero-phase delay low-pass filter with the predetermined ESS capacity. In order to verify the effectiveness of the proposed power management approach, case studies are carried out by using a 3-MW wind turbine with real wind speed data measured on Jeju Island.

최소방문 기록을 이용한 병행 시스템의 상태 공간 순회 기법 (State Space Exploration of Concurrent Systems with Minimal Visit History)

  • 이정선;최윤자;이우진
    • 한국정보과학회논문지:소프트웨어및응용
    • /
    • 제37권9호
    • /
    • pp.669-675
    • /
    • 2010
  • 이른 시스템 개발 단계에서 요구사항 에러를 찾기 위해서는 시스템의 행위가 정형 언어로 표현되어야 하고, 도달성 분석이나 싸이클 탐색과 같은 분석 기술로 분석해야 한다. 하지만 이 기술들은 시스템의 상태 공간 순회를 기반으로 하기 때문에 시스템이 복잡해지면 상태 폭발 문제가 발생할 수 있다. 즉, 순회를 위한 메모리와 수행 시간이 큰 상태 공간 때문에 기하 급수적으로 증가한다. 본 논문에서는 병행 시스템에서 이러한 문제가 나타나는 원인을 지적하고 순회에 필요한 메모리를 줄이기 위해서 병행적 상태 공간을 합성하지 않고 순회한다. 또한 수행 시간을 줄이기 위해서 방문 기록을 최소한으로 유지하는 새로운 기술을 제시한다. 마지막으로 이 기법이 효과적임을 실험 결과를 통해 보인다.

고가용성 홈 서비스 네트워크 시스템을 위한 오토노믹 자가 관리 메커니즘 (An Autonomic Self-management Mechanism for High-available Home Service Networked System)

  • 최창열;김성수
    • 한국정보과학회논문지:컴퓨팅의 실제 및 레터
    • /
    • 제13권2호
    • /
    • pp.119-130
    • /
    • 2007
  • 홈 서비스 네트워크 시스템은 실용적이면서 프로엑티브한 결함 관리를 통한 고가용도 서비스를 필요로 한다. 하지만, 홈 서비스 시스템의 복잡도가 증가하면서 고가용도 요구사항을 만족하기 위한 서비스를 제공하는 것은 더욱 어려워졌다. 더욱이, 사용자는 시스템 결함 관리와 같은 복잡한 시스템 관리를 직접 하는걸 원하지 않는다. 그러므로 홈 네트워크로 연결된 장치 또는 가전제품으로 구성된 통합 시스템의 고가용도 요구사항을 만족하면서 사람의 개입을 최소화할 수 있는 자가 관리 기능 및 원격 결함 관리 능력을 홈 서비스 시스템은 갖춰야 한다. 따라서 본 논문에서는 흠 서비스 네트워크 시스템의 가용도를 향상시키면서 관리 비용을 최소화할 수 있는 원격 자기 관리 메커니즘을 탑재한 오토노믹 자기치유 유틸리티를 설계 및 개발한다.

개에 있어서 Midazolam과 Thiopental 병용 투여시 마취 및 심순환기계에 미치는 영향 (Anesthetic and Cardiovascular Effects Induced by a Combination of Midazolam and Thiopental in Dogs)

  • 김희정;임희란;김휘율
    • 한국임상수의학회지
    • /
    • 제16권2호
    • /
    • pp.352-362
    • /
    • 1999
  • Thiopental sodium is known as ultrashort-acting barbiturates and can be employed advantageously for numerous conditions. But thiopental has the side effects of cardiovascular and respiratory systems which has barbiturates and are depend on the dose of thiopental. The side effects are reduced when the thiopental is preceded by a tranquilizer and sedative. In these drugs, benzodiazepines have the minimal effects of cardiovascular and respiratory systems. In this study, the effects of midazolam preanesthetic administration, followed by thiopental anesthetic induction, on cardiovascular system and thiopental induction requirement were studied in 14 mixed breed dogs. Cardiovascular data were recorded baseline, after premedication of saline 0.45 ml/kg or midazolam 0.1, 0.2, 0.4, 0.8 mg/kg, intubation, and 5, 10, 15, 20, 30 minutes after intubation. Extubation, head-up, sternal recombency, standing, and walking recovery times were recorded. The results were summarized as follows; (1) The 0.1, 0.2, 0.4, and 0.8 mg/kg dosages of midazolam insignificantly decreased thiopental dose requirement necessary to accomplish intubation by 6, 20, 21 and 28%. (2) The 0.1, 0.2, 0.4, and 0.8 mg/kg dosages of midazolam insignificantly reduced the times of extubation, head-up, sternal recumbency, standing, and walking recovery. (3) Midazolam was effective in reducing the frequency and duration of arrhythmia after intubation. (4) Heart rates of preanestheic midazolam administraion groups increased after thiopental injection which insignificantly changed smaller than those of control group. (5) Arterial blood pressures did not vary significantly among groups.

  • PDF

Cross Layer Optimal Design with Guaranteed Reliability under Rayleigh block fading channels

  • Chen, Xue;Hu, Yanling;Liu, Anfeng;Chen, Zhigang
    • KSII Transactions on Internet and Information Systems (TIIS)
    • /
    • 제7권12호
    • /
    • pp.3071-3095
    • /
    • 2013
  • Configuring optimization of wireless sensor networks, which can improve the network performance such as utilization efficiency and network lifetime with minimal energy, has received considerable attention in recent years. In this paper, a cross layer optimal approach is proposed for multi-source linear network and grid network under Rayleigh block-fading channels, which not only achieves an optimal utility but also guarantees the end-to-end reliability. Specifically, in this paper, we first strictly present the optimization method for optimal nodal number $N^*$, nodal placement $d^*$ and nodal transmission structure $p^*$ under constraints of minimum total energy consumption and minimum unit data transmitting energy consumption. Then, based on the facts that nodal energy consumption is higher for those nodes near the sink and those nodes far from the sink may have remaining energy, a cross layer optimal design is proposed to achieve balanced network energy consumption. The design adopts lower reliability requirement and shorter transmission distance for nodes near the sink, and adopts higher reliability requirement and farther transmission distance for nodes far from the sink, the solvability conditions is given as well. In the end, both the theoretical analysis and experimental results for performance evaluation show that the optimal design indeed can improve the network lifetime by 20-50%, network utility by 20% and guarantee desire level of reliability.

Fine-Grained and Traceable Key Delegation for Ciphertext-Policy Attribute-Based Encryption

  • Du, Jiajie;HelIl, Nurmamat
    • KSII Transactions on Internet and Information Systems (TIIS)
    • /
    • 제15권9호
    • /
    • pp.3274-3297
    • /
    • 2021
  • Permission delegation is an important research issue in access control. It allows a user to delegate some of his permissions to others to reduce his workload, or enables others to complete some tasks on his behalf when he is unavailable to do so. As an ideal solution for controlling read access on outsourced data objects on the cloud, Ciphertext-Policy Attribute-Based Encryption (CP-ABE) has attracted much attention. Some existing CP-ABE schemes handle the read permission delegation through the delegation of the user's private key to others. Still, these schemes lack the further consideration of granularity and traceability of the permission delegation. To this end, this article proposes a flexible and fine-grained CP-ABE key delegation approach that supports white-box traceability. In this approach, the key delegator first examines the relations between the data objects, read permission thereof that he intends to delegate, and the attributes associated with the access policies of these data objects. Then he chooses a minimal attribute set from his attributes according to the principle of least privilege. He constructs the delegation key with the minimal attribute set. Thus, we can achieve the shortest delegation key and minimize the time of key delegation under the premise of guaranteeing the delegator's access control requirement. The Key Generation Center (KGC) then embeds the delegatee's identity into the key to trace the route of the delegation key. Our approach prevents the delegatee from combining his existing key with the new delegation key to access unauthorized data objects. Theoretical analysis and test results show that our approach helps the KGC transfer some of its burdensome key generation tasks to regular users (delegators) to accommodate more users.

상하수처리를 위한 새로운 고효율 응집/여과 장치 (A Novel High Rate Flocculator/Filter in Water and Wastewater Treatment)

  • ;;권대영
    • 상하수도학회지
    • /
    • 제19권2호
    • /
    • pp.149-154
    • /
    • 2005
  • Conventionally used flocculation tanks require large space and high energy requirement for mixing. Static flocculators using gravel bed filter operate at a lower flow rate ($5-10m^3/m^2{\cdot}h$). Further, the cleaning of this system is difficult. A novel high rate static flocculator/filter developed at UTS packed with buoyant media such as polystyrene, polypropylene has been found to operate at higher filtration rates (30-45 $5-10m^3/m^2{\cdot}h$). They can easily be cleaned with minimal energy. Detailed experiments conducted with an artificial kaolin clay solution show that buoyant media is an excellent static flocculator in producing uniform filterable microflocs (12-15 m) even when it is operated at a high rate of 30-40 m/h. Detailed filtration experiments were conducted in a wastewater treatment plant to treat the biologically treated effluent with a floating media of depth of 120 cm. This filter was able to remove majority of phosphorus and remaining solids. It reduced significantly the fecal coliforms and fecal streptoccoci, thus requiring less amount of chlorine for disinfection. The advantage of this system is the low energy and water requirement for cleaning of filter bed. The periodic backwash adopted 30 seconds air and water and 30 seconds water cleaning every 90 minutes filter operation. Thisis equivalent to 1-2% of filtered water production. Mechanical cleaning system on the other hand, requires very low energy requirement (<1% of filtered water production).

시안화칼륨 중독으로 인해 발생한 파킨슨씨병 1례 (Parkinsonism after Cyanide Intoxication: A Case Report)

  • 서주현;어은경
    • 대한임상독성학회지
    • /
    • 제2권2호
    • /
    • pp.137-140
    • /
    • 2004
  • Acute cyanide poisoning is usually the result of attempted suicide which is often lethal within minutes or leads to a very poor prognosis after delayed and inadequate treatment. It affects the cerebral structures with the highest oxygen requirement, such as the basal ganglia, the cerebral cortex. We experienced a-45-year-old man who ingested Potassium Cyanide. He was stuporous. In 25 minutes, respiratory arrest developed and cardiopulmonary resuscitation was done. After return of spontaneous circulation, he admitted to intensive care unit, and conservative treatment was started. The clinical status was improved by degrees, but he couldn't perform daily activity like before. Minimal limitation of movement and memory deficit were left. In magnetic resonance imaging, which taken at the 11th day after admission, there were both basal ganglia and folia of cerebellum abnormality.

  • PDF

On Presupposition Projection

  • Yeom, Jae-Il
    • 한국영어학회지:영어학
    • /
    • 제3권1호
    • /
    • pp.55-88
    • /
    • 2003
  • In this paper, I will review two main theories on presupposition projection and point out their problems, and suggest the directions of a better analysis. Satisfaction theory is based on the single idea that presuppositions must be satisfied in the local context for the interpretation of a sentence. Problems occur because the theory makes only a minimal requirement on the input context for interpretation. They include the problems of weak presuppositions, unmotivated local accommodation, and projection of satisfied presuppositions. Binding theory assumes that presuppositions are anaphoric elements which can be accommodated. I will show that the syntactic notion of binding is not motivated, and claim that presupposition projection is a matter of information. Finally, I suggest the directions for a better analysis.

  • PDF