• Title/Summary/Keyword: mineral medicine

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The Relationship among Sun-Screening Agent Use, Bone Health Promotion Behavior and Bone Mineral Density of Female College Students (여대생의 자외선 차단제 사용과 골 건강증진행위 및 골밀도와의 관계)

  • Hyun, Hye Jin;Kim, Joo Hyun;Ko, Ga Yeon;Park, Bock Soon;Choi, Eun Young;Ahn, Mi Hyang
    • Journal of Korean Biological Nursing Science
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    • v.15 no.4
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    • pp.202-209
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    • 2013
  • Purpose: The purpose of this study is to investigate relationships among sun-screening agents use, bone health promotion behavior, and bone mineral density. Methods: The participants of this study were 105 female college students. The data were collected using a questionnaire about sun-screening agent use and bone health promotion behavior. Bone mineral density was measured with Ultrasound Bone Densitometer/Osteo Pro Series. Data were analyzed with the SPSS/Win 18.0 program. Results: The mean Z-score in female college students was $-1.04{\pm}1.26$, and the T-score was $-1.16{\pm}1.22$, 21.39% of the participants have osteopenia. Bone mineral density showed a significant correlation with weight. Bone mineral density showed no significant correlation between sun-screening agent use, and bone health promotion behavior. There was a significant correlation between protection power of sun-screening agents and the protection by clothes. Conclusion: According to the results of this study, we need to develop an intervention program for bone health promotion of female college students.

A Study on the Correlation between of Bone Mineral Density and Cold Hypersensitivity of Hands (골밀도와 수냉증과의 상관성 연구)

  • Lee, Dong-Nyung;Lee, Jeong-Im;Go, Ho-Yeon;Kim, Hyung-Jun
    • The Journal of Korean Obstetrics and Gynecology
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    • v.28 no.4
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    • pp.11-20
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    • 2015
  • Objectives The purpose of this study was to examine the relationship between cold hypersensitivity and bone mineral density. Methods 28 outpatients who visited OO University Oriental Hospital from July 11th, 2013 to August 28th, 2013 were analyzed. Patients were subjected to thermometer, and those with thermal difference greater than 0.3 ℃ between upper arm and palm and also with more than VAS 4 of cold hypersensitivity were diagnosed with cold sensitivity. Lumba spine (L2-4) and heel bone measurement were obtained on dual energy X-ray absorptiometry (DEXA) and Quantitative Computed Tomography (QCT). Results 1. There was statistically significant correlation between T-score of DEXA and body weight (0.522), BMI (0.643), OSTA (Osteoporosis elf-assesment Tool for Asians, 0.579), BMI, T-score and Z-score of QCT. OSTA and T-score of QCT (0.521) also had statistically significance. 2. There was no statistically significant correlation between body fat, abdominal obesity rate, degree of cold hypersensitivity, upper arm and palm's temperature difference, palm temperature, height and Z-score, T-score of QCT or T-sore of DEXA. Conclusions Bone mineral density was lower in women who had cold hypersensitivity of hand and feet. But there was no statistically significant correlation between bone mineral density and degree of cold hypersensitivity, upper arm and palm’s temperature difference.

A Study of Improvement on Low Back Pain Caused by Lumbar Disc Herniation Depending on Female Inpatient's Bone Mineral Density(BMD), Body Mass Index(BMI), Age, Pain Duration (여성의 골밀도가 요추 추간판 탈출증으로 인한 요통 호전도에 미치는 영향 및 골밀도와 비만도, 연령, 병력 기간의 관계에 관한 연구)

  • Bae, Sang-Eun;Lee, Sung-Chul;Kim, In-Joong
    • The Journal of Korean Obstetrics and Gynecology
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    • v.25 no.1
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    • pp.93-105
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    • 2012
  • Objectives: This study explored the relationships between Bone Mineral Density (BMD), Body Mass Index(BMI), Age, pain duration outcomes of treatment for Low Back Pain(LBP) in 3 groups(normal,osteopenia,osteoporosis) of female patients. Methods: We evaluated 32 cases of normal, 30 cases of osteopenia and 38 cases of osteoporosis based on BMD, BMI, Age, pain duration among the female inpatients with LBP caused by lumbar disc herniation, admitted at Jaseng Hospital of Oriental Medicine from January 2010 to December 2011. And we measured VNRS(Verbal Numeric Rating Scale) to evaluate the conservative treatment effects. Results: In improvement of female LBP caused by lumbar disc herniation, BMD(T-score), BMI had not proved correlation(P-value>0.05). Female patients' age was negatively correlated with T-score. In pain improvement, BMD normal group showed more reduction of NRS(numeric rating scale) than osteoporosis group, but that had not proved correlation(p-value=0.893). Conclusions: Statically, among the female inpatients with LBP caused by lumbar disc herniation, had no significant differences between the normal group, osteopenia group and osteoporosis group's improvement rate, depending on treating period.

A Clinical Study on the Relation between Sasang Constitution and Bone Mineral Density(BMD) in Women (성인여성(成人女性)의 사상체질(四象體質)과 골밀도(骨密度)의 상관성(相關性)에 대한 연구(硏究))

  • Kim, Hye-weon;Song, Jeong-mo
    • Journal of Sasang Constitutional Medicine
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    • v.13 no.3
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    • pp.52-58
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    • 2001
  • Purposes : As the population of old people has increased by the improvement of medical techniques, the concern on degenerative diseases has increased gradually. Especially the researches of osteoporosis have been carried out in view of prevention and treatment. But there wasn't any research related with Sasang Constitution. So we investigated the relation between Sasang Constitution and BMD(bone mineral density). Methods : Authors measured BMD and BMI(body mass index) of healthy women. We devided our subjects into Young age group and Old age group, and analyzed the data of Sasang Constitution subgroup. Results : 1. BMD of Taeumin was higher than those of Soyangin and Soeumin in Lumbar spine and Femoral neck in both Young and Old age group. In Old age group, there were significant differences in Taeumin vs Soeumin, and Soyangin vs Soeumin in BMD of Lumbar spine 2. BMI of Taeumin was higher than those of Soyangin and Soeumin in both Young and Old age group. In Young age group, there were significant differences in Taeumin vs Soyangin and Taeumin vs Soeumin. In Old age group, there were significant differences in Taeumin vs Soyangin, Taeumin vs Soeumin and Soyangin vs Soeumin. Conclusion : BMD and BMI of Taeumin was higher than those of Soyangin and Soeumin.

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Effects of Intramedullary K-wire Insertion on Femoral Lengthening in Canine with Monolateral External Fixator (단측성 외고정 기구를 이용한 개의 대퇴골 신연에 있어서 골수강내 K-강선 삽입의 효과)

  • Hwang, Jae-Min;Kim, Young-Ki;Chin, Hee-Tec;Seok, Seong-Hoon;Lee, Hee-Chun;Koh, Phil-Ok;Chang, Hong-Hee;Lee, Hyo-Jong;Yeon, Seong-Chan
    • Journal of Veterinary Clinics
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    • v.23 no.3
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    • pp.291-299
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    • 2006
  • During long bone lengthening, there are many disadvantages including axial deviation, malalignment and re-fracture which are commonly encountered inspite of its proven abilities. To study the effects of intramedullary K-wire application on the lengthening of long bone, ten skeletally mature mongrel dogs were separated into two groups(Group I, II). Right femurs of group I(5 dogs) were fixed with only monolateral external fixator after subperiosteal osteotomy. Right femurs of group II(5 dogs) were fixed with mono lateral external fixator and intramedullary K-wire after subperiosteal osteotomy. Lengthening was started at 7 days after the surgery with the rate of 0.5 mm per day for 5 weeks and the dogs were sacrificed after 15 weeks postoperatively to examine histologic differences and evaluate bone mineral density. Radiographic examination at an interval of two weeks was done to evaluate the type of callus formed and to analyze complications including instability of external skeletal fixation and axial deviation. Bone mineral density at the lengthened area and contralateral nonlengthened area were measured using quantitative computerized tomography. Histological examination of regenerated bone was performed using Masson's trichrome stain method. The radiographs demonstrated poor callus formation, higher incidence of axial deviation and screw loosening in the group I compared to the group II. The bone mineral density at the lengthened area in the group II was higher than that of the group I(P<0.05). Histological examination showed that the new bone trabeculae in the group II were greater than that of the group I. In conclusion, the combination of monolateral external fixator and intramedullary K-wire can prevent pin loosening, axial deviation and reduce healing period in dogs.

Molecular and Biochemical Characteristics of ${\beta}$-Propeller Phytase from Marine Pseudomonas sp. BS10-3 and Its Potential Application for Animal Feed Additives

  • Nam, Seung-Jeung;Kim, Young-Ok;Ko, Tea-Kyung;Kang, Jin-Ku;Chun, Kwang-Hoon;Auh, Joong-Hyuck;Lee, Chul-Soon;Lee, In-Kyu;Park, Sunghoon;Oh, Byung-Chul
    • Journal of Microbiology and Biotechnology
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    • v.24 no.10
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    • pp.1413-1420
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    • 2014
  • Phytate is an antinutritional factor that impacts the bioavailability of essential minerals such as $Ca^{2+}$, $Mg^{2+}$, $Mn^{2+}$, $Zn^{2+}$, and $Fe^{2+}$ by forming insoluble mineral-phytate salts. These insoluble mineral-phytate salts are hydrolyzed rarely by monogastric animals, because they lack the hydrolyzing phytases and thus excrete the majority of them. The ${\beta}$-propeller phytases (BPPs) hydrolyze these insoluble mineral-phytate salts efficiently. In this study, we cloned a novel BPP gene from a marine Pseudomonas sp. This Pseudomonas BPP gene (PsBPP) had low sequence identity with other known phytases and contained an extra internal repeat domain (residues 24-279) and a typical BPP domain (residues 280-634) at the C-terminus. Structure-based sequence alignment suggested that the N-terminal repeat domain did not possess the active-site residues, whereas the C-terminal BPP domain contained multiple calcium-binding sites, which provide a favorable electrostatic environment for substrate binding and catalytic activity. Thus, we overexpressed the BPP domain from Pseudomonas sp. to potentially hydrolyze insoluble mineral-phytate salts. Purified recombinant PsBPP required $Ca^{2+}$ or $Fe^{2+}$ for phytase activity, indicating that PsBPP hydrolyzes insoluble $Fe^{2+}$-phytate or $Ca^{2+}$-phytate salts. The optimal temperature and pH for the hydrolysis of $Ca^{2+}$-phytate by PsBPP were $50^{\circ}C$ and 6.0, respectively. Biochemical and kinetic studies clearly showed that PsBPP efficiently hydrolyzed $Ca^{2+}$-phytate salts and yielded myo-inositol 2,4,6-trisphosphate and three phosphate groups as final products. Finally, we showed that PsBPP was highly effective for hydrolyzing rice bran with high phytate content. Taken together, our results suggest that PsBPP has great potential in the animal feed industry for reducing phytates.

Relationship of Obesity and Bone Mineral Density in Women Dwelling in the Community (지역사회거주 여성의 비만도와 골밀도와의 관계)

  • Kang, Hyun-Sook;Kim, Jong-Im;Bak, Won-Sook;Song, Rha-Yun;Ahn, Yang-Heui;Lee, In-Ok;Lim, Nan-Young;Cho, Kyung-Sook;Choi, Sun-Ha;Han, Sang-Sook
    • Journal of muscle and joint health
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    • v.14 no.2
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    • pp.181-187
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    • 2007
  • Purpose: The purpose of the study was to identify the relationship between obesity and bone mineral density in middle aged women. Methods: A cross-sectional survey design was utilized with a check list and physiological measurements. A total of 827 convenient samples were recruited from women who lived in the community. Bone mineral density was measured by T-score using the pixi method of Lumar on the left heel. Descriptive statistics and pearson correlation coefficient were utilized for data analysis. Results: Most were assessed as having normal weight(37.9%) or obese (57.4%) by BMI. Only 32% was assessed as having normal bone mineral density, while 40.3% had osteopenia, and 27.7% as osteoporosis. The BMI scores were significantly related to age, and episodes of fractures. Those with lower bone mineral density reported significantly more episodes of fractures and chronic disease. The T scores of Bone mineral density were significantly correlated with the scores of BMI (r= .126, p< .001). Conclusion: There is a strong need to develop intervention programs for this age group to manage bone mineral density loss to prevent occurrences of osteoporosis, and episodes of fracture.

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Factors Affecting Bone Mineral Density of the Femur in Parkinson's Disease Patients (파킨슨병 환자의 골밀도 영향요인)

  • Kim, Sang Hee;Lee, Eun Nam;Park, Eun Young;Kim, Jae Woo
    • Journal of muscle and joint health
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    • v.19 no.3
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    • pp.350-361
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    • 2012
  • Purpose: The purpose of this study is to explore the level of bone mineral densities of the femur neck and to identify factors affecting bone mineral density of the femur in Parkinson's disease (PD) patients. Methods: Participants were 121 PD patients visiting the outpatient clinic of D University Hospital in B City. Bone mineral density was measured at the femur neck by using a dual-energy x-ray absorptiometry. The serum vitamin D level, the amounts of milk intake, caffeine intake, cigaret smoking, and alcohol consumption, and the number of steps taken daily were measured. Past and present disease history, the medication history, and duration of the disease were also collected. The level of disability was obtained by neurologists using the Hoehn and Yahr stage and the Unified Parkinson's Disease Rating Scale. Results: Among PD patients, 57% had osteopenia and 15.7% had osteoporosis. The bone mineral density of the femur was associated with weight, serum vitamin D level, age, and working status. Conclusion: The identification of weight and serum vitamin D level as important predictive factors emphasizes the importance of balanced nutrition for PD patients.

Mineralized Undifferentiated Duodenal Carcinoma in a Shih-Tzu Dog

  • Lee, Jiyeong;An, Soyon;Hwang, Gunha;Go, Woohyun;Lee, Jong-Bong;Noh, Seul Ah;Lee, Dongbin;Song, Joong-Hyun;Hwang, Tae Sung;Lee, Hee Chun
    • Journal of Veterinary Clinics
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    • v.39 no.5
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    • pp.258-263
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    • 2022
  • An eight-year-old, intact female, Shih-Tzu, weighing 4.5 kg presented with complaints of anorexia, pale mucous membrane, and vomiting for the past 5 days. On physical examination, nausea, abdominal pain, and melena were noted. On hematologic examination, severe anemia and thrombocytosis were identified. On radiographs examination, soft tissue opacity with small faint mineral opacity mass in the mid-abdomen and two mineral opacity regions in the cranial aspect of mass were identified. Ultrasonographic findings showed thickening of descending duodenal wall with loss of layering and mineralization within the duodenal wall and mesentery adjacent to the duodenal lesion. Computerized tomography showed circumferential wall thickening of descending duodenum with mineralization. Mineralization of the mesentery and mesenteric lymph nodes was identified. Based on the diagnostic imaging, the tentative diagnosis was descending duodenal tumor with dystrophic mineralization. Endoscopy revealed mucosal hemorrhage and erythema within the descending duodenum and stomach. Surgery was performed, and mineralization in the pancreatic tail to duodenum and mesentery was found. Resection of the duodenum, regional lymph node, and mineralized pancreatic region and the duodenal anastomosis were performed. The histologic examination revealed a high-grade undifferentiated duodenal carcinoma with metastases to the regional lymph node and mesentery. The patient was managed with supportive therapy for 8 days and discharged. The patient was followed up for 5 months and there were no complications.