• 대한화장품학회지
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• 제33권4호
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• pp.227-230
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• 2007

최근 기능성화장품과 피부관련 의약품 분야에서 multi-lamellar와 liquid crystal의 구조가 커다란 관심을 끌고 있다. 결합수와 고정된 유상을 함유하는 multi-lamellar 구조는 피부의 세포간지질의 lamellar 구조의 재건과 보습을 유지하는 작용으로써 보습기능이나 장벽기능의 복구에 우수하며, 이 지질들은 각질층에 침투하여 유지된다. 본 연구에서 고급 지방 알코올, 레시틴, 콜레스테롤을 사용하여 제조한 bio-mimic liquid crystal emulsion (BLCE)의 피부장벽 기능을 측정하였고 일반적인 계면활성제와 세포독성을 비교하였다.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2000년도 ITC-CSCC -2
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• pp.1009-1012
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• 2000

In this paper, we have designed and fabricated power PHEMT’s with an unit gate width of 80$\mu\textrm{m}$ and 4 fingers, and MIMIC power amplifiers using the PHEMT’s as well. The PHEMT’s have a 0.2$\mu\textrm{m}$ gate length and source to drain spacing of 3$\mu\textrm{m}$. The characteristics of the fabricated PHEMT’s are 4.08dB of S$\sub$21/ gain at the 35GHz and 317mS/mm of gm, and 62GHz of f$\sub$T/ and 120GHz of f$\sub$max/. The designed and fabricated MIMIC’s power amplifiers with 6 PHEMT’s and MIN capacitors were fully passivated by 1000 Α of Si$_3$N$_4$ film for higher performance and surface protects. The chips were processed using the MINT processes, and size was 3.25 ${\times}$ 1.8$\textrm{mm}^2$. The fabricated MIMIC power amplifiers have RF characteristics such as 11.25dB of S$\sub$21/ gain, 11.37dB of input return-loss and 12.69dB of output return-loss at the 34.55GHz.

• 셀메드
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• 제14권2호
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• pp.3.1-3.2
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• 2024

The purpose of this study is to consider the health and well-being of singing, an expression activity of language. There are also many studies in which singing activities have a positive effect on individual quality of life and social activities. Therefore, this study attempted to suggest that more effective singing is being performed by increasing empathy through various expressions of onomatopoeia and mimic words. Love Changbu Taryeong (愛倡夫打令) is Korea's traditional representative Gyeonggi folk song. It is a cheerful and lyrical folk song based on the five scale of Sol-ra-do-re-mi. It sings not only human joy, sorrow, and pleasure, but also natural phenomena and scenes. It is an exciting rhythm based mainly on the Gutgeori jangdan (rhythmic pattern, 12/8) but it is a rhythm that you can feel the sadness in it. In particular, various onomatopoeia and mimic words appear in this song, making you think about the fun of singing and the origin of the language. Therefore, this study attempted to examine that more effective singing is becoming more effective by increasing empathy through various expressions of onomatopoeia and mimic words. You can watch our singing activities on YouTube.(https://youtu.be/IhnBqWiK-3w?si=AAMi2BVes9mPShnr)

• International Journal of Molecular Medicine
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• 제43권6호
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• pp.2319-2328
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• 2019

Exosomes serve important functions in cell-to-cell communication and biological functions by serving as a delivery cargo shuttle for various molecules. The application of an improved delivery method for microRNAs (miRNAs/miRs) may enhance their potential as a therapeutic tool in cardiac diseases. Thus, the present study investigated whether human peripheral blood-derived exosomes may be used as a delivery cargo system for miRNAs, and whether the delivery of miR-21 using a human peripheral blood derived-exosome may influence the degree of remodeling following myocardial infarction (MI). In H9C2 and HL-1 cells, miR-21 expression was successfully regulated by treatment with human peripheral blood derived-exosomes loaded with an miR-21 mimic or inhibitor compared with untreated cells. In addition, the mRNA and protein expression levels of SMAD family member 7 (Smad7), phosphatase and tensin homolog (PTEN) and matrix metalloproteinase 2 (MMP2), which are involved in cardiac fibrosis, were associated with the uptake of miR-21 mimic- or inhibitor-loaded exosomes. Similarly, the in vivo mRNA and protein expression of Smad7, PTEN and MMP2 were altered following treatment with miR-21 mimic- or inhibitor-loaded exosomes. Furthermore, miR-21 mimic-loaded exosomes enhanced fibrosis, whereas miR-21 inhibitor-loaded exosomes reduced fibrosis in a mouse MI model. These results suggested that miRNA-loaded human peripheral blood derived-exosomes may be used as a therapeutic tool for cardiac diseases.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2005년도 추계종합학술대회
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• pp.583-586
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• 2005

In this paper, millimeter-wave monolithic integrated circuit (MIMIC) low noise amplifier (LNA) for V-band, which is applicable to 58 GHz, we designed and fabricated. We fabricated the module using the fabricated LNA chips. The V-band MIMIC LNA was fabricated using the high performance $0.1\;{\mu}\;m$ ${\Gamma}-gate$ pseudomorphic high electron mobility transistor (PHEMT). The MIMIC LNA was designed using active and passive device library, which is composed $0.1\;{\mu}\;m$ ${\Gamma}-gate$ PHEMT and coplanar waveguide (CPW) technology. The designed V-band MIMIC LNA was fabricated using integrated unit processes of active and passive device. Also we fabricated CPW-to-waveguide fin-line transition of WR-15 type for module. The Transmission Line was fabricated using RT Duroid 5880 substrate. The measured results of V-band MIMIC LNA and Module are shown $S_{21}$ gain of 13.1 dB and 8.3 dB at 58 GHz, respectively. The fabricated LNA chip and Module in this work show a good noise figure of 3.6 dB and 5.6 dB at 58 GHz, respectively.

• 대한전자공학회논문지TC
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• 제41권4호
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• pp.45-50
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• 2004

본 논문에서는 소자 결합 구조를 통해 발진전력이 합쳐지는 회로를 이용한 저전압, 고효율 Q-band MIMIC 발진기를 제안한다. 0.1 ㎛ GaAs PHEMTS와 CPW 전송라인을 사용하여 제안된 구조의 발진기를 성공적으로 집적화하였다. 제작된 발진기는 34.56 ㎓ 주파수에서 2.6 ㏈m의 출력 전력일때 19 %의 높은 효율특성을 가졌다. 이때 회로에 인가된 전압은 2.2 V로 현재까지 Q-band에서 발표된 발진기보다 낮은 구동전압 특성을 얻었다. 또한 최대 출력 전력은 34.56 ㎓ 주파수에서 6.7 ㏈m을 얻었다.

• 대한전자공학회논문지TC
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• 제40권11호
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• pp.34-41
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• 2003

본 논문에서는 MINT의 0.1㎛ PHEMT MIMIC 공정을 이용하여 제작한 광대역 증폭기와 주파수 혼합기를 사용해서 60㎓ 무선랜 송ㆍ수신 시스템을 설계 제작하였다. RF단 송신기의 출력파워는 0㏈m, 이득은 1.7㏈ 얻었고, 수신기의 노이즈 특성은 4.2㏈, 이득은 1.57㏈를 얻었다. 구현된 시스템은 통신거리 35m이상 거리에서 BER 10/sup -6/ 이하로 통신할 수 있다. 신호의 왜란과 은닉성이 강한 DSSS 방식을 사용하여, 단거리 비밀 통신을 목적으로 개발하였다.

• 한국해양바이오학회지
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• 제2권1호
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• pp.11-22
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• 2007

This aims to review natural products transformed by mimic intestinal metabolisms with microorganisms and hydrolytic enzymes, which exhibit enforced biological activity, higher extraction yield and identification of active components. In the process, transformation to the smaller active compounds with enzymes and microbes mimics the pharmacological action of natural products by intestinal bacteria. In order to establish conditions for the fermentation and enzyme reaction, it is required to choose several natural products for biotransformation and investigate the optimal conditions for the fermentation or the enzyme reaction such as composition, temperature, pH, inoculum, and cultivation time. It is expected an increase of the internal absorption of the active materials without regard to the intestinal microbes or its ability through biosynthesis of the active materials by the microbes and enzymes. And this techniques can be applied to biotransformation of natural products such as sesaminol, resveratrol, 1-deoxy nojirimycin, naringenin, quercetin, and baicalin and to the metabolism study using the animal model.

• 전기의세계
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• 제26권1호
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• pp.87-90
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• 1977

Various simulation techniques were developed in the modeling of biological system during the last decades. Mostly analog and hybrid simulation techniques have been used. The authors chose the Digital Analog Simulation (DAS) technique by using the MIMIC language to simulate the saccadic eye movement system performances on the digital computer. There have been various models presented by many investigators after Young & Stark's sampled-data model. The eye movement model chosen by the authors is Robinson's model III which shows the parallel information processing characteristics clearly to the double-step input stimuli. In the process of simulation, the parameter and constants used were based on the neurophysiological data of the human and animals. The analog model blocks were converted to the corresponding MIMIC block diagrams and programmed into the MIMIC statements. The program was run on the CDC Cyber 72-14 computer. The essential input stimulus was double-step of 5 and 10 degrees, and target durations chosen were 50,100 and 150 msec. The results obtained by the DAS technqiue were in good agreement with analog simulation carried out by other investigators as well as with the experimental human saccadic eye movement responses to double-step target movements.

• Bulletin of the Korean Chemical Society
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• 제6권4호
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• pp.228-230
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• 1985

(Z)-13-Octadecen-1-yl acetate, the pheromone mimic of the Rice Leaf Folder Moth, Cnaphalocrosis medinalis, was synthesized from 1,13-tridecanediol in three steps. Monoacetylation of 1,13-tridecanediol followed by PCC oxidation gave 13-acetoxytridecan-1-al. Wittig olefination of the 13-acetoxytridecan-1-al with pentylidenetriphenylphosphonium ylide afforded (Z)-13-octadecen-1-yl acetate, the pheromone mimic of the Rice Leaf Folder.