• 제목/요약/키워드: military IT

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Suppression of MED19 expression by shRNA induces inhibition of cell proliferation and tumorigenesis in human prostate cancer cells

  • Cui, Xingang;Xu, Danfeng;Lv, Chao;Qu, Fajun;He, Jin;Chen, Ming;Liu, Yushan;Gao, Yi;Che, Jianping;Yao, Yacheng;Yu, Hongyu
    • BMB Reports
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    • 제44권8호
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    • pp.547-552
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    • 2011
  • MED19 is a member of the Mediator that plays a key role in the activation and repression of signal transduction or the regulation of transcription in carcinomas. To tested the functional role of MED19 in human prostate cancer, we downregulated MED19 expression in prostate cancer cells (PC-3 and DU145) by lentivirus-mediated short hairpin (shRNA), and analyzed the effect of inhibition of MED19 on prostate cancer cell proliferation and tumorigenesis. The in vitro prostate cancer cell proliferation, colony formation, and in vivo tumor growth in nude mice xenografts was significantly reduced after the downregulation of MED19. Knockdown of MED19 caused S-phase arrest and induced apoptosis via modulation of Bid and Caspase 7. It was suggested that MED19 serves as a novel proliferation regulator that promotes growth of prostate cancer cells.

중국의 군사적 부상과 역내 해양안보 - 주변국의 전략적 대비 및 유사를 중심으로 - (China's Military Rise and Regional Maritime Security - Its Neighbors' Strategic Calculations and Various Contingencies -)

  • 김태호
    • Strategy21
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    • 통권33호
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    • pp.113-147
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    • 2014
  • While China's military rise is an issue of growing importance to regional security, it is worthwhile to note that it is not China's military modernization per se, but its capacity to project and sustain power along and beyond its borders--in particular, the possibility to resolve forcefully its outstanding maritime disputes and various contingencies. This essay argues that China's "anti-access capability"--a U.S.-coined term originally developed for a Taiwan contingency--is equally applicable to other major regional cases such as the Spratly disputes and a North Korean contingency. Furthermore, notwithstanding China's continuos efforts to develop and deploy various types and classes of weapons/platforms, it is the Russian systems and technologies that are most capable and thus likely assigned to the highest mission-critical areas. In assessing China's current and likely future military capability as well as their implications for the region, it is necessary to take note of the following: • There exists asymmetry of military capability between China and its weaker neighbors. While the PLAN is weak in several important aspects, for instance, many of its neighbors' navies are weaker still. • Some have argued that China's foreign policy behavior apparently became more "assertive" in 2009-2013, but it is wiser to keep in mind that China has almost always been assertive and aggressive when it comes to what China defines as "sovereignty and territorial issues" as well as its newest "core interests." • On the South China Sea disputes it is the function of U.S. presence in the theater--in the form of overseas bases and the freedom of navigation--and the PLA's own limitations to project and sustain power for an extended period of time that have largely prevented armed. • While Taiwan remains the idee fixe of China's diplomacy and military, it is and will be a tough nut to crack. China's recent creeping attempts for economic integration with Taiwan should be seen in this context. • China and Japan, the two regional heavyweights and traditional rivals, will likely have a bilateral relationship that is replete with difficulties and tension. China's unilateral announcement of its ADIZ in November 2013 as well as the occasional yet persistent disputes with Japan over the Senkaku/Diaoyudao/Diaoyutai islands are only the latest manifestation of this deeper and difficult relationship. • For Korean security it is imperative to take into account the geostrategic and historical factors. On top of the existing military threats from North Korea, the ROK should be able to employ a) hedging strategy, b) "limited defense sufficiency" strategy, and c) rock-solid relations with the United States.

군사훈련으로서의 가라테 가치와 국방 체육적 효과 (Value of Karate and Effects of Defense physical as Military Training)

  • 박용성;이경행;박상혁
    • 문화기술의 융합
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    • 제10권4호
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    • pp.467-472
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    • 2024
  • 본 논문은 가라테의 역사와 군사훈련으로서의 활용, 그리고 국방체육으로서의 가치에 대해 고찰하였다. 가라테는 오키나와에서 기원한 무술로, 근대 들어 일본 군대의 훈련에 도입되면서 세계적으로 널리 보급되었다. 특히 제2차 세계대전 당시 일본군은 백병전에 대비해 가라테 훈련을 강화하였고, 전후 주일 미군을 통해 가라테는 서구 사회에 전파되었다. 현대 군대에서도 가라테를 포함한 각종 무술이 군사훈련에 활용되고 있다. 미 해병대의 MCMAP, 이스라엘 군의 크라브마가 등이 대표적인 군사무술 프로그램이다. 이들은 가라테, 유도, 복싱 등 다양한 무술의 기술을 융합해 실전에 최적화된 체계를 갖추고 있다. 군 교육에서 가라테는 개인의 신체적·정신적 능력 향상과 부대 전체의 전투력 강화에 기여하고 있다. 격렬한 수련을 통해 체력과 정신력을 기를 수 있고, 백병전 상황에 대비한 실전 기술 습득이 가능하다. 나아가 동료와의 호흡을 맞추는 단체훈련을 통해 전우애와 단결력도 다질 수 있다. 다만 현대전의 양상 변화로 군 교육에서 무술 훈련의 비중과 방식에 대한 재고가 필요해 보인다. 첨단 무기의 발달로 개인 간 격투보다는 팀 단위 작전 수행 능력이 더욱 중요해졌기 때문이다. 전통 가라테의 기술체계를 그대로 적용하기보다는 현대전에 맞게 변형·발전시킬 필요가 있을 것이다. 그럼에도 불구하고 강인한 체력, 불굴의 정신력, 전우애 등 군인의 핵심 자질을 함양하는 데 있어 가라테를 포함한 무술 수련의 가치는 여전히 유효하다. 앞으로도 각국 군대는 시대 변화에 맞춰 무술 훈련 체계를 발전시켜 나갈 것으로 전망된다.

김정은시대 개성공단 실무회담 분석을 통한 군사협상 변화 연구 (Study on Changes in Military Negotiations under the Kim Jeong-eun Regime through Working-Level Talks for Gaeseong Industrial Complex)

  • 이성춘
    • 융합보안논문지
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    • 제13권5호
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    • pp.3-10
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    • 2013
  • 김정일시대 군사협상 분석 모델인 '항일유격대식 협상모델'을 활용하여 최근에 실시된 개성공단 실무회담 분석을 통하여 김정은시대에 개최될 군사협상의 지속과 변화를 제시하고자 한다. 특히, 개성공단 실무회담 분석을 통하여 김정은 시대의 경제분야 협상에서도 군사회담과 유사한 협상행태가 진행되고 있음을 확인할 수 있었다. 이와 같은 분석을 통하여 유추할 수 있는 사항은 김정은시대 군사협상에서도 김정일시대의 군사협상 범주에서 협상이 진행될 것이라는 사실이다. 근본적으로 북한은 변화의 길을 걷겠지만 현 시점에서는 기존의 전략문화를 변경하기 보다는 그 틀 속에서 군사협상 목적을 달성하려 할 것이다. 이러한 현상은 당분간 지속될 것이다. 향후 북한은 경제난 극복을 위하여 군사협상에 변화를 꾀할 것이다. 따라서 우리 정부의 군사협상에 대한 인식의 대전환이 있어야 할 것이다. 우리정부는. 대화와 협상을 유도하기 위해서 지속적으로 노력하여야 한다. 북한의 변화를 유도하기 위해서는 군사 협상에 적용할 수 있는 통일 전선논리를 활용한 경제 분야 협상 의제를 개발하여야 한다. 이를 이용하여 북한의 군사협상 정책결정자들에게 논리체계를 형성하여 준다면 새로운 군사협상의 틀을 만들 수 있을 것이다. 북한은 변화를 통한 경제적 교류협력을 보장하는 길이 생존하고 발전하는 길임을 인식하여야 한다.

Impact of ITSM Military Service Quality and Value on Service Trust

  • Woo, Hanchul;Lee, Sangdo;Huh, Jun-Ho;Jeong, Sukjae
    • Journal of Multimedia Information System
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    • 제7권1호
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    • pp.55-72
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    • 2020
  • As the IT service environment grows, it is critical in terms of IT service quality to minimize the occurrence of failures due to changes in applications and to diagnose and recover in a short period of time how failure will affect the business. Thus, the Defense Acquisition Program Administration (DAPA) has been building and operating ITSMs to implement IT service management in a leading manner. Information Technology Service Management (ITSM) is divided into events, obstacles, changes, versions and setup management to ensure flexibility and stability in service delivery. It is also operated separately from service level, availability, capacity, financial and IT service continuity management to ensure service quality and cost efficiency. Based on ITSM military service history, this study looks at the impact of quality of service on value, satisfaction, and trust. The results of the analysis are highly valuable for future ITSM implementation and operation.

구조방정식 모형을 이용한 군(軍) 정비부대 서비스품질과 고객만족 측정에 관한 연구 (A study of Military-Vehicle Maintenance Service Quality and Customer Satisfaction by Structural Equation Model(SEM))

  • 서정환
    • 한국경영과학회:학술대회논문집
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    • 한국경영과학회 2007년도 추계학술대회 및 정기총회
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    • pp.171-175
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    • 2007
  • The Service sector has increased in importance over the last decade in troops. Military included public sector, but has very different peculiarity from other public institution. So it's necessary that developing an evaluation tool that measuring service quality and customer satisfaction for troops. This study was conducted to identify tile service quality factors which are utilized to measure military vehicle maintenance service quality and customer satisfaction. In this paper, developing a Structural Equation Model at 'three dimensional model of service quality', and it is applied to customers of military vehicle maintenance service.

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저장탄약 신뢰성 향상을 위한 ASRP 발전방안 연구 (A Study on the Development of ASRP for Improvement of the Stockpile Ammunition Reliability)

  • 최석철;배윤호;김동억
    • 한국군사과학기술학회지
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    • 제8권4호
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    • pp.32-40
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    • 2005
  • The ASRP(Ammunition Stockpile Reliability Program) is a overall evaluation system of ammunitions to improve the combat strength, having a short history. The storage lifetime of ammunitions, more than 20 years since being produced, differs according to storage circumstance and period. And it shows the different reliability for munitions. Because most ammunitions in military have been stored for a long time, these ammunitions need to be evaluated to maintain Serviceability, Reliability, Safety and Performance for the use of military. In this paper, it suggested the need to develop the techniques for ourselves, to make more laboratories for surveillance and testing and to extend research funds & concerns.

이동 IP 체계에 대한 군 정보체계 활용방안 연구 (A Study on Mobile IP Systems for Military Information Systems)

  • 이태종
    • 한국국방경영분석학회지
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    • 제22권2호
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    • pp.73-89
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    • 1996
  • This paper suggests the new IP, SIMIP(Simple Mobile IP), which supports a continuous mobility between a static host and a mobile host in the static TCP/IP LAN environment where mobile hosts are overlayed with cells. For designing a mobile protocol, routing optimization is very important, and it is directly related to the management mechanism of a mobile host's location information. When the mobile hosts' location information are centralized, the network has high risk when a centralized device fails. On the other hand, when they are distributed, the above problems are solved. But it requires complicated techniques in order to search the encapsulated addresses. SIMP centralizes mobile hosts' location information, minimizes the risk by automatically substituting the failed default mobile router with one of the multiple general mobile routers, and supports the optimal routing path through "default mobile router path alternation" Then since SIMIP isn't reasonable the operations informations to the chief in military operations room.ions room.

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한국군복의 변천연구 (Study on the military uniform)

  • 김정자
    • 대한가정학회지
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    • 제24권4호
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    • pp.27-50
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    • 1986
  • The military uniform is worn to defend against enemy. Its function has an important effect on its changing. As once the means of combat was the collective formation, soldiers fought with swords and bows, or on horses. After the invention of gun powder, however, it became changed to the scattering formation. Therefore, it became impossible to fight on great armors any more. the armors and helmets made of iron, used light, materials, became those of Doosuingab (豆錫鱗甲), Soejagab(鎖子甲), Pigab(皮甲), Jigab(紙甲). The Doojunggab(頭釘甲) which presented a grand appearance came into existence. At last the Chullic and GooGoonbok made of clothing were worn. Korean military uniform were influenced by Chines military uniform. Korean armors had an influence on Japanese. As follows, I will study on Chinese and Korean armors with the changes of the times.

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기동무기체계에서의 통신을 위한 음성신호 포착 연구 (A Study of Voice signal Capture for communication in the AFV)

  • 김석봉;이성태
    • 한국군사과학기술학회지
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    • 제6권1호
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    • pp.81-90
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    • 2003
  • In the military communication environment, it is very difficult to obtain clear voice signal due to the high level noise. The purpose of this study is to find out the best body spot to get the vocal chords signal by measuring the skin or the bone conducting vibrations of different body positions within the noise environment. Based on the experimental study, it was found out that the measurement of sound signal within the ear is the best way to get the voice which comes from the vocal chords and this method can prevent the interruption of noise. This study will give the effective voice communication method in the high noise environment and be applicable to military purpose.