• 제목/요약/키워드: miR-29a-3p

검색결과 100건 처리시간 0.032초

중년여성의 지각된 생활 스트레스와 자아존중감 및 우울의 관계 (Relationships among Perceived Life Stress, Self-esteem and Depression in Middle-Aged Women)

  • 박금자;이지현;김미옥;방부경;윤수정;최은주
    • 지역사회간호학회지
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    • 제13권2호
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    • pp.354-362
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    • 2002
  • Objectives: This study was conducted to examine the relationships among perceived life stress, self-esteem, and depression in middle-aged women. Methods: Data were collected from March 30 to May 25, 2000. The study subjects were 123 middle-aged women living in Pusan. The instruments used for this study were the Perceived Life Stress scale developed by Lee (1984), based on the original scale designed by Yu, et al. (1994), Self-esteem scale developed by Rho, et al. (1997), and the Depression scale developed by Ahn (1988). For data analysis, the SPSS PC+ was utilized, by which frequency and percentage, mean and standard deviation, t-test, ANOVA, Sheffe's test and Pearson's correlation coefficients were examined. The reliability of the instruments were tested by Cronbach's $\alpha$, showing the internal consistency of 0.7328 for the self-esteem scale. and 0.8987 for the depression scale. Results: 1) The results showed a relatively low perceived life stress score in the middle-aged women with a mean and standard deviation of 363.18 and 72.92 (range: .00 - 1877.38). 2) The results showed a relatively high self-esteem score in the middle-aged women with a mean and standard deviation of 29.77 and 5.06 (range: 10 - 40). 3) The results showed a relatively high depression score in the middle-aged women with a mean and standard deviation of 39.46 and 9.38 (range: 0 - 61). 4) There were no statistically significant differences in perceived life stress by demographic related factors. 5) There were statistically significant differences in self-esteem by health status (F=8.930, p= .000) and economic status (t=4.792, p= .010). 6) There were statistically significant differences in depression by age (F=3.770, p= .0261). education (F=4.850, p= .003) and regularity of menstrual cycle (F=13.180, p= .000). 7) There was no statistically significant correlation between perceived life stress, and self-esteem in the middle-aged women (r=-.077, p= .399). 8) There was no significant correlation between perceived life stress. and depression in the middle-aged women (r= .010, p= .916). 9) There was a significant negative correlation between self-esteem, and depression in the middle-aged women (r=- .359, p= .000). Conclusion: Higher self-esteem was related to a lower depression status. Therefore, it is necessary to elevate the level of self-esteem in order to reduce the level of depression in middle-aged Korean women.

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교정환자의 자아존중감과 구강건강영향지수(OHIP)에 영향을 미치는 요인 (Maincause of influencing oral health impact profile(OHIP) and self-esteem of orthodontic patients)

  • 박영남;이미라
    • 한국치위생학회지
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    • 제10권3호
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    • pp.513-522
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    • 2010
  • Objectives : This study aimed to determine self-esteem and oral health impact profile (OHIP) of orthodontic patients to get data necessary for the process of consultation, education, and treatment for those patients who hoped to get orthodontic therapy in order to see effects of orthodontic therapy on personal life in consideration of general characteristics of those patients under orthodontic therapy. methods : A self-administered questionnaire was used among 232 outpatients under orthodontic therapy from October to November 2009, obtaining the following results. Results : 1. As for general characteristics of respondents, those under 19 years of age constituted 46.6%; the unmarried comprised 85.8%; and students constituted 53.4%. 2. Most respondents were getting orthodontic therapy for beauty (41.8%) and dental health (40.5%). Family (54.3%) contributed to their decision to get orthodontic therapy; parents or siblings (62.5%) were bearing the treatment expenses. 3. Females were getting orthodontic therapy for an aesthetic purpose (50.3%), and male for the purpose of dental health (44.6%) (P<0.01). 4. OHIP was slightly higher among males ($4.10{\pm}0.61$) than among female ($4.00{\pm}0.78$), and was highest among those 19 years old and under ($4.17{\pm}0.67$); the older they were, the lower it was significantly (P<0.05). Most of them were earning 3 to 4 million won ($4.22{\pm}0.72$); the married ($4.05{\pm}0.74$) constituted higher percentage. As for occupation, students ($4.13{\pm}0.66$) comprised the highest percentage. 5. Self-esteem was higher among males ($3.83{\pm}0.47$) than among females ($3.80{\pm}0.50$), and was highest among those 25 to 29 years old ($3.92{\pm}0.46$). Most of them were earning more than 5 million won ($3.91{\pm}0.42$), which was statistically significant (P<0.01). The married ($3.91{\pm}0.54$) constituted higher percentage than the unmarried ($3.80{\pm}0.48$); office managers ($3.95{\pm}0.55$) comprised the highest percentage. 6. As for correlation between variables effecting OHIP of orthodontic patients, there was negative correlation in age (r=-0.225) and positive correlation in occupation (r=0.122). As for correlation between variables effecting self-esteem of orthodontic patients, there was negative correlation in occupation (r=-0.130) and positive correlation n income (0.126), while there was positive correlation (r=0.202) between OHIP and self-esteem of orthodontic patients. Conclusions : Younger orthodontic patients who were students showed higher OHIP, and professionals earning more showed higher self-esteem. Orthodontic patients with higher OHIP showed higher self-esteem. Therefore, it is necessary to develop a program based on OHIP and self-esteem in consulting and treating orthodontic patients; since it is considered that orthodontic therapy will improve appearance, enhance self-confidence, and have positive effects on interpersonal relationships and quality of living, researches are necessary on constant changes in psychological properties.

가족의 지지와 제왕절개술 산모의 자아개념간의 관계연구 (A Study on the Relationship Between Perceived Family Support & Self Concept of Cesarean Section Mothers)

  • 장명자;이미라
    • 모자간호학회지
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    • 제1권
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    • pp.23-33
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    • 1991
  • Recently, Cesarean Section has been revealed as major events in maternity nursing, because it has influence on tile formatter of the self concept of cesarean section mothers as well as later coping mechanism and mother-child relationship including the mothering role. The study is conducted to clarify the relationships between the perceired family support and the self concept of cesarean section mothers, and to find out other Influencing factors on the formation of the self concept. Measuring instrument used in this study was Lee's scale to measure the self concept and the degree of perceived family support of the cesarean section mothers, The subject were 155 cesarean section mothers who were selected conveniently. Volunteers answered self reporting questionnaires which asked about their self concept. Data was analyzed as follows using SAS. The relationship between scores of the self concept and degree of the perceived family support was analyzed by Pearson's product moment correlation. In order to identify the influencing effects of demographic variables on the formation of self concept & F test were used. Result were summarized as follows : 1. Scores of self concept of cesarean section mothers were significantly correlated with scores of the perceived family support (r=0.3438, p<0.01) These results show that the family support is closely related to the self concept of cesarean mothers and has positive effects on their coping capacity. 2. Scores of self-concept of those who have lower ducation background and are multipara were significantly higher than those who have higher education background and are primipara(M=29.90$\pm$9.37, 27.69$\pm$3.89, t=2.006, df=105.8, p=0.0480: M=27.75$\pm$3.49. 29.46$\pm$8.68, t=-1.7183, 2. p=0.08).

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체외수정시술시 유전자 재조합 난포자극호르몬제의 효용성 (The Efficacy of Recombinant Human Follicle Stimulating Hormone (rhFSH) in Human IVF-ET Program)

  • 한국선;이홍복;송인옥;박용석;변혜경;전진현;궁미경
    • Clinical and Experimental Reproductive Medicine
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    • 제29권1호
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    • pp.45-56
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    • 2002
  • Objectives: Recently, recombinant FSH (rFSH) has been manufactured using a Chinese hamster ovary cell line transfected with the gene encoding human FSH. Both rFSH and urinary gonadotropin (uFSH) could be used for controlled ovarian hyperstimulation (COH). However, uFSH implies a number of disadvantages, such as batch-to-batch inconsistency, no absolute source control, dependence on large amounts of urine, low specific activity, and low purity. The purpose of this study was to evaluate the efficacy of rFSH in human IVF-ET program. Materials and Methods: A total of 508 infertile women was enrolled in this study. They are classified into rFSH group (n=177) or uFSH group (n=331), and all of them were matched by age and cause of infertility in same period. The $Puregon^{(R)}$ (Organon, Holland) was used as rFSH, and the Metrodin-$HP^{(R)}$ (Serono, Switzeland) and $Humegon^{(R)}$ (Organon, Holland) was used as uFSH. We subdivided the patients into three age groups. The outcomes of IVF-ET program were analyzed using the statistical package for social sciences (SPSS). Results: There was no significant differences in the level of estradiol on hCG injection day, the numbers of retrieved oocytes, matured oocytes, fertilized oocytes, transferred embryos, frozen embryos between the two groups. The total dose (IU) of gonadotropin for COH was significantly lower in the rFSH group compared to uFSH group ($1339{\pm}5491.1$ vs $2527.8{\pm}1075.2$ IU, p<0.001). Clinical pregnancy rate per embryo transfer in the rFSH group showed increasing tendency, compared to the uFSH group, but there was no statistical significance (35.2% vs 29.3%). Our results demonstrated that the relative efficiency of rFSH compared with uFSH is higher in older patients. Conclusions: The ovarian stimulatory effect and clinical outcome of recombinant FSH was similar to that of the urinary gonadotropin. The IVF-ET cycles with significantly lower dose of gonadotropin in rFSH group showed comparable results. Therefore, we suggest that recombinant FSH is more potent and effective than urinary gonadotropin.

응급구조(학)과 학생의 전공선택 동기와 전공만족도 및 직업관 (The Motivation of selecting major, the satisfaction of major and view of occupation for EMT students)

  • 김미숙;박소미;;서하얀;주영주;이경열;최은숙
    • 한국응급구조학회지
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    • 제14권3호
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    • pp.29-40
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    • 2010
  • Purpose: We investigated the motivation of selecting major, the satisfaction of major and the view on occupation of emergency medical technology (EMT) students. The results of study will be used to increase the satisfaction of major of university students. Also, it can be used to support decision of major for high school students. Method: We conducted 1,586 surveys from 665 students at six four-year colleges and 921 students at seven three-year colleges. Our research period was from Aug. 27th to Oct. 31st in 2010. The surveys were analyzed by SPSS 18.0 using description statistics, t-test, ANOVA, Scheffe and Pearson correlation coefficient. Result: In our study, the motivation of selecting major is 35.8% of students selected 'good employment prospects', satisfaction of major's $M{\pm}SD$ is $3.15{\pm}.486$, adaptation of major's $M{\pm}SD$ is $3.11{\pm}.472$. The satisfaction of major show difference (t = 4.548 p = .000) by sex, also the adaptation of major show difference (t = 2.279, p = .023) by sex. The satisfaction of major show first grade students higher (F = 3.605, p = .013) than fourth grade students at four-year colleges. If satisfaction of major is high, accumulation evaluation score is high (F = 3.276, p = .011), too. Clinical practice experienced students was higher (t = -2.878, p = .004) than non experienced it satisfaction. In view of occupation, ideal job's factors and actual job's factors a lot of students selected 'aptitude'. Also, there is a statistically significant correlation (r = .618, p = .000) between the satisfaction of major and the adaptation of major. High satisfaction indicates high adaptation of major. Conclusion: In our study satisfaction of major and adaptation of major was very high score. EMT students concern about employment prospects at most. It is inferred that they select job which match with one's aptitude. We can suppose that students select major as a tool for employment by seeing result that a lot of students consider employment prospects at most when they select major. A method to improve the satisfaction and adaptation of major should be developed by realizing problems which occur the dissatisfaction of major. Also, there as on why students conflict between ideal and actual job should be revealed. There as on seems students want stable occupation in unstable job market situation. Therefore, the expansion of job matching aptitude and being stable should be processed. Finally, university should actively support the method that help to finding jobs for student by identifying job preparation of students.

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흡연, 음주, 운동과 건강생활양식 (The health lifestyle of adults related to smoking, drinking and exercise)

  • 소희영;이미라;정미숙
    • 한국보건간호학회지
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    • 제12권2호
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    • pp.221-235
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    • 1998
  • This study is a descriptive survey to explore the health lifestyle of adults. The study subjects are teachers of elementary. middle and high school. and staffs of research institutes located in Chungchung Province and Daejon city. The data was collected from Jan. to march 1997 through self reporte for structured questionnaire. Fantastic check list of Wilson and Ciliska for Health Lifestyle Assessment and DSM-III-R for somatic symptom were used as tools. Data was analysed by frequency, $X^2_test$, t-test and Anova using SAS program. The results are as follows: 1. There were statistically significant differences In drinking(t=7.75, P=.000), exercise(t=-2.99, P=.003)and interpersonal relationship(t=2.22, P=.027) among 10 health lifestyle between smoking group and non-smoking group, in drinking(t=17.98, P=.000), exercise(-4.71. P=.000), and job satisfaction(t=2.22, P=.027) between drinking group and non-drinking group, and in eating habit(t=-2.00, P=.045), drinking (t=4.47, P=000), exercise (t= -16.49, P=000), keeping traffic law(t= -2.68, P=.007), personality (t= -2.05, P=.040) and anxiety/depression(t=-3.47, P=.000) between exercise group and non-exercise group. 2. There was statistically significant difference in cardiovascular symptom(F=4.22, P=.0l) among somatic symptoms of subjects according to exercise level. 3. There was statistically significance difference in lifestyle according to smoking level(F=, 3.33, P=.011), drinking level(F=9.17, P=.0001) and exercise level(F=11.93, P=.000l), and in somatic symptom according to sex(t=-3.93, P=.0001), weight(F=3.83, P=.022), exercise level (F=3.29, P=.03) among general characteristics. 4. There was statistically significant difference between sex in general (t= -3.64, P=.0001), gastrointestinal(t=-2.21, P=.02), musculoskeletal(t=-3.92, P=.001), and total symptom (t= -3.92, P=.0001). 5. There was statistically very highly signigicant difference In weight according to smoking($x^2=25.18,\; P=.001)$ and exercise$(x^2=16.46,\; P=001)$. 6. There was statistically significant difference in frequency between smoking group, drinking group and exercise group$(x^2=24.52,\;P=.001)$. Among a number of habit, smoking, drinking and exercise are important factors of human health to prevent related disease morbidity and death. It is essential for industrial health nurse to committ in this subject considering the influence of those factors and lifestyle on health. There is also a relationship of weight with smoking and exercise, the frequency of overweight/obesiy in smoking/ no-exercise group were high. It is quite necessary for the people having cardiovascular symptom to exercise to lower morbidity and mortality. The industrial health nurse has to keep In mind on this point and consider of time and facilities of fitness of employee. It needs to explore the cause by further research on somatic symptom of women. This research shows that concerning the relationship between smoking, drinking, and exercise, health care provider must take not only management of disease, but health behaviors and lifestyle into consideration.

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ANALYSIS OF THE LiF:Mg,Cu,Si TL AND THE LiF:Mg,Cu,P TL GLOW CURVES BY USING GENERAL APPROXIMATION PLUS MODEL

  • Chang, In-Su;Lee, Jung-Il;Kim, Jang-Lyul;Oh, Mi-Ae;Chung, Ki-Soo
    • Journal of Radiation Protection and Research
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    • 제34권4호
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    • pp.155-164
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    • 2009
  • In this paper, we used computerized glow curve deconvolution (CGCD) software with several models for the simulation of a TL glow curve which was used for analysis. By using the general approximation plus model, parameters values of the glow curve were analyzed and compared with the other models parameters (general approximation, mixed order kinetics, general order kinetics). The LiF:Mg,Cu,Si and the LiF:Mg,Cu,P material were used for the glow curve analysis. And we based on figure of merits (FOM) which was the goodness of the fitting that was monitored through the value between analysis model and TLD materials. The ideal value of FOM is 0 which represents a perfect fit. The main glow peak makes the most effect of radiation dose assessment of TLD materials. The main peak of the LiF:Mg,Cu,Si materials has a intensity rate 80.76% of the whole TL glow intensity, and that of LiF:Mg,Cu,P materials has a intensity rate 68.07% of the whole TL glow intensity. The activation energy of LiF:Mg,Cu,Si was analyzed as 2.39 eV by result of the general approximation plus(GAP) model. In the case of mixed order kinetics (MOK), the activation energy was analyzed as 2.29 eV. The activation energy was analyzed as 2.38 eV by the general order kinetics (GOK) model. In the case of LiF:Mg,Cu,P TLD, the activation energy was analyzed as 2.39 eV by result of the GAP model. In the case of MOK, the activation energy was analyzed as 2.55 eV. The activation energy was analyzed as 2.51 eV by the GOK model. The R value means different ratio of retrapping-recombination. The R value of LiF:Mg,Cu,Si TLD main peak analyzed as $1.12\times10^{-6}$ and $\alpha$ value analyzed as $1.0\times10^{-3}$. The R of LiF:Mg,Cu,P TLD analyzed as $7.91\times10^{-4}$, the $\alpha$ value means different ratio of initial thermally trapped electron density-initial trapped electron density (include thermally disconnected trap electrons density). The $\alpha$ value was analyzed as $9.17\times10^{-1}$ which was the difference from LiF:Mg,Cu,Si TLD. The deep trap electron density of LiF:Mg,Cu,Si was higher than the deep trap electron density of LiF:Mg,Cu,P.

유기용제 폭로작업자들의 후천성 색각이상 평가 (The Assessment of Acquired Dyschromatopsia among Organic-Solvents Exposed Workers)

  • 강미정;강수희;서석권;신동훈;이종영
    • Journal of Preventive Medicine and Public Health
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    • 제29권3호
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    • pp.529-538
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    • 1996
  • 이 연구는 산업장에서 색각이상과 관련된 유기용제 폭로근로자들에서 후천성으로 발생할 수 있는 색각이상을 정성적이고 정량적으로 평가하고 색각이상에 영향을 미치는 요인을 조사하고자 저농도의 유기용제 폭로근로자 70명과 대조군 47명을 대상으로 실시하였다. 한식 이중 15색상 배열 검사기를 이용한 색각이상을 평가한 결과 색상배열의 착오 비율과 정량적으로 산출한 색 혼란지수는 유기용제 폭로군과 대조군간 차이가 없었다. 색 혼란지수와 연령과의 선형관계는 두 군 모두에서 연령이 증가할수록 색 혼란지수가 유의하게 증가하였으며(p<0.05), 각 연령군별로 층화한 색 혼란지수의 중앙값은 폭로군이 대조군보다 높게 나타났으나 29세이하 연령군에서만 통계학적으로 유의하였다. 15색상 배열검사의 배열형태에 따라 분류한 색각이상의 유병률은 두 군 모두에서 21%로 차이가 없었으며 색 혼란지수에 대해 연령, 흡연, 음주상태 및 유기용제 폭로유무를 독립변수로 하여 다중회귀분석을 실시한 결과 연령이 유의한 변수로 나타났다(p<0.05). 이상의 결과로는 유기용제 폭로와 색각이상 발생과의 관련성을 제시할 수 없으며, 추후 색각이상 평가를 위한 색상배열 검사의 표준환경 설정, 유기용제 폭로 근로자들의 개개인의 폭로정도 평가, 그리고 색각이상 검사결과를 정확하게 분류하는 기준 등에 대한 연구가 필요할 것이라고 생각되며, 또한 저농도의 유기용제에 폭로되는 근로자들의 색각이상의 평가는 정성적이고 정량적인 방법을 통한 평가가 바람직하며 일시적인 평가보다는 추적관찰을 통한 정량적인 지수의 변화를 관찰해야 할 것으로 생각된다.

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광중합형 복합레진의 화학적 분해와 마모에 관한 연구 (CHEMICAL DEGRADATION AND WEAR OF LIGHT-CURED COMPOSITE RESINS)

  • 양규호;정희경;최남기;김선미
    • 대한소아치과학회지
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    • 제34권2호
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    • pp.273-284
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    • 2007
  • 본 연구는 광중합형 복합레진 Composan LCM Flow(Promedica, Germany), Clearfil ST(Kuraray medical, Japan) Durafil VS(Heraeus Kulzer, U.S.A), Point 4(Kerr, U.S.A)를 사용하여 각 제품의 물리적, 화학적 평가를 하고자 하였다. 마모시험 후 마모된 면의 깊이를 측정하였고 0.1N NaOH에 보관 후. 각 제품의 분해저항성을 무게손실, 표면하 분해층 깊이, 용출된 Si 농도를 기준으로 평가하였으며 주사전자현미경과 공촛점 레이저 현미경으로 분해 층을 관찰하여 다음과 같은 결과를 얻었다. 1. 무게 손실량은 $1.02{\sim}6.04%$까지 다양하였으며 Durafil VS에서 가장 높았다$(6.04{\pm}0.29%)$. 2. 분해층 깊이는 Durafil VS이 가장 깊었고 Clearfil ST, Point 4, Composan LCM Flow순이었고 Point 4와 Composan LCM Flow는 다른 제품과 유의한 차이를 보였다(p<0.001). 3. Si 용출량은 Clearfil ST가 가장 많았으며 Durafil VS, Composan LCM Flow, Point 4 사이에 유의한 차이를 보였다(p<0.001). 4. 주사전자현미경 관찰시 표면 양상 및 분해층 깊이를 관찰할 수 있었고 공촛점 레이저 현미경 관찰시 NaOH 용액에 보관한 후 수복재의 기질과 충전제 사이의 결합의 파괴 양상을 관찰할 수 있었다. 5. 최대마모깊이는 Durafil VS, Composan LCM Flow, Point 4, Clearfil ST 순으로 낮았으며 유의한 차이를 보이지 않았다(p>0.001). 6. 각 제품의 Si 용출량과 분해층 깊이 사이(r=0.892, p<0.01), Si 용출량과 무게손실 사이(r=0.736, p<0.01)에는 유의한 상관관계를 보였다.

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Allometric Relations of Take-off Speed and Power with Body Mass of Anuran Amphibians

  • Choi, In-Ho;Shin, Jae-Seung;Kim, Mi-Hyun
    • Animal cells and systems
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    • 제2권4호
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    • pp.477-481
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    • 1998
  • Previous studies have postulated that isometric animals exert similar locomotory capacity (speed, distance) because the amount of energy available for the motion would be the same regardless of body mass (m). To test propriety of this theory, we examined body shape and take-off potential of two frog species, Rana nigromaculata (powerful jumpers) and Bombina orientalis (slow hoppers). Morphological measurements included thigh muscle mass (indicative of total muscle force), hindlimb length (L, determining acceleration distance), and interilial width (shaping take-off motion). To gauge locomotory capacity, take-off speed (v) and take-off angle ($\theta$) were measured from video analyses, and jump distance (R) and take-off Power ($P_{t}$ ) were calculated from equations $R=V^{2}sin2\theta/g$ and ($P_{t}$$㎷^{3}/2L$(where g is the gravitational constant). Scaling exponents of morphometric variables for both species were 0.96-1.11 for thigh muscle mass, 0.28-0.29 for hindlimb length, and 0.30-0.36 for interilial width. Scaling exponents of locomotory performance for the two species were -0.01-0.14 for take-off speed, 0.24-0.31 for jump distance, and 0.66-0.84 for take-off power. The results demonstrate that the frogs of this study showed isometric body shape within species, but that take-off response changed allometrically with body mass, indicating that these data did not fully support the previous proposition. An exception was found in take-off speed of B. orientalis, in which the speed changed little with body mass (slope=-0.01). These findings suggest that the energy availability approach did not properly explain the apparent allometric relations of the take-off response in these animals and that an alternative model such as a power production approach may be worth addressing.

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