• Title/Summary/Keyword: miR-25

Search Result 441, Processing Time 0.03 seconds

The Effect of Pain in Patients with Ankylosing Spondylitis on Sleep Disturbance: Focusing on the Mediating Effect of Fatigue (강직성 척추염 환자의 통증이 수면장애에 미치는 영향: 피로의 매개효과를 중심으로)

  • Cho, Ok-Hee;Lim, Jong Mi;Hwang, Kyung-Hye
    • Journal of muscle and joint health
    • /
    • v.25 no.2
    • /
    • pp.104-111
    • /
    • 2018
  • Purpose: The purpose of this study was to investigate the mediating effect of fatigue on the relationship between pain and sleep disturbance in patients with ankylosing spondylitis. Methods: The subjects of this study were 109 patients with ankylosing spondylitis who visited the rheumatology department in a university hospital. Subjects completed structured questionnaires measuring pain, sleep disturbance, and fatigue. Data were analyzed using t-test, Pearson's correlation coefficients, and 3-step regression analysis. Results: Pain was positively correlated with fatigue (r=.60, p<.001) and sleep disturbance (r=.45, p<.001). Fatigue was positively correlated with sleep disturbance (r=.55, p<.001) and had a mediating effect on the relationship between pain and sleep disturbance. Conclusion: The findings confirm that pain in patients with ankylosing spondylitis affects fatigue and its accumulation has a mediating effect on increasing the level of sleep disturbance. In clinical practice, education on symptom management for patients with ankylosing spondylitis needs to be provided for encouraging proper exercise and rest. Patient education should also include strategies to reduce fatigue and promote sleep in daily lives in addition to pain management.

The Effects of Boards' and Directors' Characteristics on R&D Investment: In the Korean Context (이사회 및 이사의 특성이 기업의 연구개발투자에 미치는 영향: 한국기업을 중심으로)

  • Lim, Mi-Hee
    • Journal of Technology Innovation
    • /
    • v.25 no.2
    • /
    • pp.1-34
    • /
    • 2017
  • This paper seeks to explore the effects of the board structure and director characteristics on the R&D investment of a company. The results from analyzing 95 Korean listed companies reveal that the directors' demographic characteristics substantially affect the R&D intensity. When the directors are younger, major in science or engineering, and have an experience of studying abroad, they tend to be supportive of R&D, thereby increasing the R&D expenditure. Particularly, the effects of insider directors are shown to be greater than those of outside directors, which implies that the Korean corporate boards are mainly operated by insiders. Furthermore, when the relative power of boards is greater than the management, the effects of inside directors, rather than overall directors, on R&D intensity are weakened.

Studies on the permeability and dissolvability of cathodic electrolyzed water (음극전리수의 침투력과 용해력 연구)

  • Kim Jum-Ji;Kang Dong-Kyu;Ryoo Kun-Kul;Lee Yoon-Bae;Lee Jong-Kwon;Lee Mi-Young
    • Proceedings of the KAIS Fall Conference
    • /
    • 2005.05a
    • /
    • pp.292-294
    • /
    • 2005
  • 본 연구에서는 전기영동 겔에 대한 음극전리수의 침투력과 녹차성분에 대한 음극전리수의 용해력을 일반 물과 서로 비교하였다. 음극전리수와 증류수로 제조한 CBB-R 염색시약으로 polyacrylamide 겔 상에서 단백질을 다양한 시간 동안 염색한 후 염색강도를 서로 비교하였다. 그 결과 음극전리수로 제조한 CBB-R 염색시약은 증류수로 제조한 CBB-R 염색시약보다 같은 반응 시간 동안에 먼저 단백질을 강하게 염색시켰다. 뿐만 아니라 $25^{\circ}C$에서 음극전리수는 일반 물에 비하여 녹차성분에 대해 극히 탁월한 용해력을 나타내었다.

  • PDF

지상파 DMB가 ITU 국제표준으로 승인되기까지

  • Kim, Gyeong-Mi
    • Information and Communications Magazine
    • /
    • v.25 no.6
    • /
    • pp.48-51
    • /
    • 2008
  • 우리나라는 Eureka-147 방식의 디지털 라디오를 이동 멀티미디어로 확장하기로 하고 지상파 DMB로 불리는 비디오규격을 개발하였다. 지상파 DMB의 국제표준화를 위해 우리나라가 2004년 3월에 시스템 개요와 필드 테스트 결과를 ITU-R에 기고함에 따라 ITU-R 내에서 본격적인 이동 멀티미디어 표준화 논의가 시작되었고 우리나라 지상파 DMB 외에 일본의 ISDB-T, 노키아의 DVB-H와 퀄컴의 FLO 등을 대상으로 이동 멀티미디어 시스템 표준으로 개발하게 되었다. 3년여에 걸쳐 각 국간의 첨예한 이해관계에 의한 의견충돌과 합의를 거쳐 표준안이 작성되었으며, 표준화 방식은 휴대수신용으로 한정하고 각 시스템들을 알파벳에 따른 멀티미디어 시스템으로 명명하였다. 우리나라 지상파 DMB는 유럽 진출을 염두에 두고 디지털 음성방식 A인 Eureka-147 과의 호환성을 강조하기 위해 멀티미디어 시스템 A로 이름을 붙이기로 하였다. 지난 4월에 열린 ITU-R SG 6 회의에서 이동 멀티미디어의 표준화를 최종적으로 결정되었고 이후 회원국의 동의회신 절차를 거쳐 2007년 12월에 지상파 DMB가 ITU에서 휴대이동방송 시스템 중 하나로서 승인되었다.

Dielectric Characteristics of Different Filler Content in Pb-free White Dielectric Layer (Pb-free 백색유전체에서 filler함량에 따른 유전체 특성)

  • An, Yong-Tae;Choi, Byung-Hyun;Lee, Jung-Min;Jee, Mi-Jung;Kim, Hyung-Sun
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
    • /
    • 2007.11a
    • /
    • pp.36-36
    • /
    • 2007
  • $R_2O_3$(R=Bi, B)-RO(R=Ba, Zn)를 주성분으로 하는 Pb-free유리프리트에 높은 굴절률을 가지고 있는 $TiO_2$ filler를 첨가하여 PDP용 백색유전체를 제조하였다. $TiO_2$ type, 함량에 따른 백색유전체로의 반사율 및 유전 특성을 조사하였다. 백색유전체를 소성한 결과 rutile과 anatase를 중량비로 75:25로 혼합하여 $520^{\circ}C$에서 소성한 경우 밀도 및 수축율의 변화를 거의 나타나지 않았다. 그러나 $TiO_2$함량이 15wt.%를 혼합하여 첨가했을 경우 반사율은 높고 접합특성 또한 우수하였다. 또한, 유전상수는 $TiO_2$첨가량이 증가함에 따라 증가하는 경향을 나타내었다.

  • PDF

Flowering and Growth of Dendrobium phalaenopsis as influenced by Photoperiod, Temperature, and Plant Growth Regulators (온도, 일장 및 식물생장조절제에 의한 덴파레의 생육 및 개화 반응)

  • Lee, Young-Ran;Kim, Mi-Seon;Kim, Jae-Yeong
    • FLOWER RESEARCH JOURNAL
    • /
    • v.16 no.4
    • /
    • pp.247-254
    • /
    • 2008
  • This study was conducted to investigate effect of temperature, photoperiod, and plant growth regulators on the growth and flowering of Dendrobium phalaenopsis. Photoperiod treatments of 10 or 16 day length were from Mar. 24 to May 23. After treatments, all plants were exposed under natural photoperiod. Temperature treatments promoted development of new shoots (leads) of Dendrobium phalaenopsis 'Semi Alba' at $30/25^{\circ}C$(day/night) for 12 weeks, and 16 hr-photoperiod treatment promoted development of new shoots and flowering. The 16 hr photoperiod Dendrobium phalaenopsis 'Candistraipe ${\times}$ Tedtakiguz' no difference in the numbers of flower, flower width, and stalk length compared to the 10 hr photoperiod. Days to first flowering from appearance of new shoot were 241 days under natural photoperiod, 243 days under 10 hr, and 216 days under 16 hr, so that 16 hr-photoperiod treatment was faster about 25 days than that of natural or 10 hr treatment. There was not significant difference in growing and flowering of Dendrobium phalaenopsis among plant growth regulators.

Preparation and Characterization of Poly(vinyl alcohol)/ Sodium Alginate Blend (Poly(vinyl alcohol)/ Sodium Alginate 블렌드의 제조 및 특성)

  • Koo, Won-Mi;Jung, Du-Kam;Lee, Young-Hee;Kim, Han-Do
    • Proceedings of the Korean Fiber Society Conference
    • /
    • 2001.10a
    • /
    • pp.25-28
    • /
    • 2001
  • Polymer blending constitutes a most useful method for the improvement or modification of the physicochemical properties of polymeric materials. Some of the polymer blends exhibit unusual properties, unexpected from homopolymers. An important property of a polymer blend is the miscibility of its component, because it affects the mechanical properties, the morphology, its permeability and degradation [1, 2]. (omitted)

  • PDF

The Effect of Stress and Sleep Quality on Depression among Nursing Students during Clinical Practice

  • Kwon, Mi-Hyoung
    • Journal of the Korea Society of Computer and Information
    • /
    • v.25 no.10
    • /
    • pp.169-177
    • /
    • 2020
  • The purpose of this study is to identify the effects of stress and sleep quality on depression during clinical practice of nursing students. The subjects of the study were third and fourth graders who experienced clinical practice for more than a semester among nursing students at C University in one region. A total of 107 people were analyzed. Most of the nursing students experienced more than moderate stress and depression during clinical practice, and the quality of sleep was low. During clinical practice, the stress of nursing students showed a weak correlation with the quality of sleep(r=.393, p<.001), and depression showed a strong net correlation with stress(r=.588, p<.001), the quality of sleep(r=.591, p<.001). Factors affecting depression during clinical practice were stress and the quality of sleep. Therefore, effective management methods that can relieve the stress of nursing college students during clinical practice and improve the quality of sleep and active nursing strategies that can prevent depression should be sought.

Subjective Health Status, Job Stress and Andropause Symptoms among Middle-aged Male who Work

  • Kwon, Mi-Hyoung;Oh, Ji-Hyun
    • Journal of the Korea Society of Computer and Information
    • /
    • v.25 no.9
    • /
    • pp.109-116
    • /
    • 2020
  • In this study, we tried to identify the relationship between subjective health Status and job stress and andropause symptoms of middle-aged male who work.. The data was based on a survey of male aged 40 to 59 in four cities and collected by surveying 154 people with jobs. The general characteristics of the difference in andropause symptoms were marital status and job satisfaction. 68.83 percent of the subjects experienced andropause symptoms. There was a negative correlation between subjective health status and job stress(r=-.204, p=.011). The correlated factors of andropause symptoms included subjective health status(r=-.248, p=.002) and job stress(r=.341, p=<.001). Factors influencing andropause symptoms are job stress, subjective health status. There is a need to develop and apply nursing intervention programs that can reduce job stress and improve subjective health status in order to effectively manage menopause symptoms of middle-aged male who work.