• Title/Summary/Keyword: metabolizng enzyme activities

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Biological Activities of Lysimachiae Herba I. -Effects of the Pretreatment of Lysimachiae Herba on the Enzyme Activities in Galactosamine-intoxicated Rats- (금전초(金錢草) 성분의 생리활성 I. -금전초의 추출분획의 전처리가 갈락토사민 중독 흰쥐의 대사효소활성에 미치는 영향-)

  • Kim, Hoe-Young;Kim, Soon-Shin;Lee, Chung-Kyu;Choi, Jong-Won
    • Korean Journal of Pharmacognosy
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    • v.27 no.1
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    • pp.58-64
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    • 1996

  • Pretreatment of the methanolic extract(250-500mg/kg, p.o., two weeks) of Lysimachiae Herba prevented the elevation of ALT and AST activities in galactosamine(GalN, 400 mg/kg, i.p.) intoxicated rats. Its five fractions, especially the ethyl acetate fraction, also showed significant preventing actions on damaged liver metabolizing enzyme functions by GalN intoxication.

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