• Title/Summary/Keyword: metabolic study

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Nomogram for screening the risk of developing metabolic syndrome using naïve Bayesian classifier

  • Minseok Shin;Jeayoung Lee
    • Communications for Statistical Applications and Methods
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    • v.30 no.1
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    • pp.21-35
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    • 2023
  • Metabolic syndrome is a serious disease that can eventually lead to various complications, such as stroke and cardiovascular disease. In this study, we aimed to identify the risk factors related to metabolic syndrome for its prevention and recognition and propose a nomogram that visualizes and predicts the probability of the incidence of metabolic syndrome. We conducted an analysis using data from the Korea National Health and Nutrition Survey (KNHANES VII) and identified 10 risk factors affecting metabolic syndrome by using the Rao-Scott chi-squared test, considering the characteristics of the complex sample. A naïve Bayesian classifier was used to build a nomogram for metabolic syndrome. We then predicted the incidence of metabolic syndrome using the nomogram. Finally, we verified the nomogram using a receiver operating characteristic curve and a calibration plot.

The Metabolic Syndrome and Associated Lifestyle Factors among Older Adults (서울시내 일개 복지관에 내원하는 노인의 대사증후군 발생양상과 관련요인에 대한 연구)

  • Choi, Seung-Hye;ChoiKwon, Smi
    • Journal of Korean Biological Nursing Science
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    • v.13 no.1
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    • pp.53-60
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    • 2011
  • Purpose: The purpose of the present study was to investigate the prevalence and lifestyle factors related to the metabolic syndrome in Korean elderly. Methods: A total number of 122 elderly over 60 yr were recruited from a community elderly center. Elderly were classified into young old (60-74 yr) and old (75-84 yr). Metabolic syndrome was defined by third report of the national cholesterol education program (NCEP) expert panel on Adult Treatment Panel III (ATP III). Abdominal obesity was determined by Korean society for the study of Obesity criteria. The nutritional status was measured by mini nutritional assessment (MNA). Results: The prevalence of the metabolic syndrome was significantly higher in the old than young old elderly (p<0.05, respectively). Abdominal obesity and hypertension were the most common risk factors. The related factors to metabolic syndrome were high Body mass Index (BMI) and currently not participating in exercise. Abdominal obesity, low HDL cholesterol and hypertension were associated with specific nutrient intakes. Conclusion: A strategy to decrease the metabolic syndrome in the elderly is urgently needed particularly so for the old elderly. A nutritional and exercise program for young old elders may be helpful reducing the prevalence of metabolic syndrome in later stage.

The Management Strategies of Metabolic Syndrome among Workers through the Literature Review (문헌고찰을 통한 근로자의 대사증후군 관리방안 제시)

  • Choi, Eun Sook;June, Kyung Ja
    • Korean Journal of Occupational Health Nursing
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    • v.14 no.2
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    • pp.138-152
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    • 2005
  • Purposes: The purposes of this study are to investigate the definition, components, prevalence, and associated factors of metabolic syndrome and suggest the management strategies for workers. Method: This study was conducted by literature review. Results: Metabolic syndrome by the NCEP-ATP III is the clustering of three or more of five conditions: abdominal obesity, high triglycerides, low levels of HDL cholesterol, high blood pressure, and high glucose(blood sugar). The prevalence of the metabolic syndrome by modified NCEP-ATP III in South Korean workers was about 20 to 25%. Metabolic syndrome is caused by many associated factors, namely, age, family history, socioeconomic status, job strain, shift work, psychosocial distress, bad health behaviprs and so on. Conclusions: To prevent metabolic syndrome at worksites, multifactorial risk factor assessments and preventive approaches are required. Socioeconomic factors such as education, working status should be nationally importantly considered for the health inequality of workers. Occupational health nurse, at first, can start weight control, smoking cessation program. stress management, the improvement of work environment. Next stage, early diagnosis and treatment for metabolic risk group can be performed.

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Association between Job-related Factors and Metabolic Syndrome among Male and Female Workers: Using the Korean National Health and Nutrition Examination Survey (남녀 근로자의 직업 관련 특성과 대사증후군 - 국민건강영양조사 자료를 이용하여 -)

  • Do, Kyung-A;Jung, Hye-Sun;Choi, Eun-Hi
    • Korean Journal of Occupational Health Nursing
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    • v.24 no.1
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    • pp.39-47
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    • 2015
  • Purpose: This study is performed to help manage the metabolic syndrome in work place by identifying the effect on metabolic syndrome with subjects of Korean adult workers. Methods: Using part of data of "The Fourth Korean National Health and Nutrition Examination survey 2nd year (2008)" which center for disease control is investigating. The general characteristics include age, educational level, occupation and marital status as factors affecting the metabolic syndrome of workers in this study. Results: Work-related factors are the working environment in which they are working while they are pressed for time due to work status and overload. If the work status of worker is unpaid family member, the risk is increased by more than twice compared to paid workers. The risk for metabolic syndrome in work environment to work while fighting the clock is decreased compared to the work environment without time pressure. Conclusion: In order to manage the metabolic syndrome of workers, health promotion program to change management of both working condition and working environment can contribute to prevent the metabolic syndrome and ultimately prevent the cerebrocardiovascular diseases.

Effect of Non-Alcoholic Fatty Liver Disease on Components of Metabolic Syndrome in Post-menopausal Women

  • Shim, Moon-Jung;Im, Jee-Aee
    • Biomedical Science Letters
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    • v.14 no.4
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    • pp.225-231
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    • 2008
  • Non-alcoholic fatty liver disease (NAFLD) is associated with various metabolic abnormalities, including central obesity, type 2 diabetes, dyslipidemia, and high blood pressure. This suggests that NAFLD may represent the hepatic manifestation of the metabolic syndrome. In this study, we investigated unfavorable effects NAFLD on components of metabolic syndrome in post-menopause women. Eight hundred sixty-nine postmenopausal women were recruited for this study. The diagnosis of fatty liver was based on the results of abdominal ultrasonography. Serum levels of fasting glucose, total cholesterol, triglyceride, and HDL-cholesterol were measured. The prevalence of component of metabolic syndrome such as hypertension, hyperglycemia, hypertriglyceridemia, and low-HDL-cholesterol was significantly higher in subjects with NAFLD as compared with those without NAFLD. The moderate to severe grade of NAFLD presented higher levels of serum fasting glucose, fasting insulin, HOMA-IR, total cholesterol, and triglycerides than the mild NAFLD and the normal group. In conclusion, metabolic syndrome risk was increased in post-menopause women with NAFLD as compared with those without NAFLD. The severity of NAFLD affected metabolic syndrome risk factors. The optimal strategy for the treatment of NAFLD is likely to include lifestyle modifications and therapy to improve insulin resistance.

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Triglyceride and Glucose (TyG) Index is a Clinical Surrogate Marker for the Diagnosis of Metabolic Syndrome

  • Shin, Kyung-A
    • Biomedical Science Letters
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    • v.23 no.4
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    • pp.348-354
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    • 2017
  • TyG (triglyceride and glucose) index using triglyceride and fasting blood glucose is recommended as a useful marker for insulin resistance. The present study evaluated the usefulness of TyG index in diagnosing metabolic syndrome and suggested an optimal cut-off value. The subjects of this study were adult 4,415 adults aged 20 to 80 years who underwent health screening at J General Hospital from January 2016 to January 2017. Metabolic syndrome was based on AHA/NHLBI (American Heart Association/National Heart, Lung, and Blood Institute) criteria. TyG index correlated with metabolic syndrome risk factors including HOMA-IR. Compared with the participants in the lowest quartile of TyG index, odds ratios and 95% confidence intervals for metabolic syndrome were 8.5 (3.005~23.903), 20.0 (17.190~23.407) for those in the third, and the fourth quartile of TyG index. The optimal cut-off value of the metabolic syndrome was 8.81 for TyG index (sensitivity 86.7%, specificity 80.1%) and area under the ROC curve (AUC) was 0.894. In conclusion, TyG index is effective to identify individuals at risk for metabolic syndrome.

The Association between hs-CRP Concentration of Blood and Metabolic Syndrome in the Residents of a Rural Community (일부 농촌지역 주민들의 혈중 hs-CRP 농도와 대사증후군 위험인자와의 관계)

  • Kim, Jong-Im
    • Korean Journal of Community Nutrition
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    • v.15 no.6
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    • pp.796-805
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    • 2010
  • This study investigated the correlations and risk distribution differences between high sensitivity C-reactive protein (hs-CRP) and the diagnosis factors of metabolic syndrome among the residents of a rural community. Two thousand adults aged from 40 to 70 were recruited and 1,968 subjects were included in the study after excluding those with infectious disease or with hs-CRP higher than 10 mg/L in blood. The subjects were then divided into three groups of hs-CRP to examine the correlations and risk ratio with the risk factors of metabolic syndrome. There was a tendency of hs-CRP increasing according to the number of risk factors of metabolic syndrome. The risk ratio with hs-CRP according to metabolic syndrome significantly increased by 2.0 and 2.2 times in the intermediate and high risk group, respectively, compared with the low risk group. The risk ratio with the risk factors of metabolic syndrome according to hs-CRP rose in abdominal obesity, triglyceride, and W/Ht in the intermediate risk group of hs-CRP. The risk ratio also surged in high pressure, W/Ht, ex-drinking (1.7 times), exsmoking (2.0 times) and current smoking (2.0 times) in the high risk group. The results indicate that hs-CRP is related to the risk factors of metabolic syndrome and that it's very important to manage obesity including abdominal obesity and W/Ht and everyday habits including drinking and smoking.

Discriminating Factors of Stages of Change for Exercise among Patients with Metabolic Syndrome (대사증후군 환자의 운동행위 변화단계 판별요인)

  • Hwang, Hyun Ju;Lee, Eun Nam;Choi, Eun Jung
    • Journal of muscle and joint health
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    • v.21 no.1
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    • pp.46-54
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    • 2014
  • Purpose: This study was designed to explore the stage distribution of subjects according to stages of change for exercise and to identify factors that could discriminate subjects in various stages. Methods: The sample consisted of 182 subjects who had metabolic syndrome. The instruments used in this study were the stage placement instrument for exercise, the metabolic syndrome knowledge and metabolic syndrome health belief scale, and the metabolic syndrome exercise self efficacy scale. Data were analyzed using chi-square, ANOVA, and discriminant analysis by using the SPSS 19.0 program. Results: For exercise stages, exercise efficacy, occupation, and exercise benefit showed high standardized canonical discriminant function coefficients. Subjects in precontemplation/contemplation stage for exercise were more likely to have occupations, had less exercise efficacy and exercise benefit than those in other stage. Conclusion: This study implies that the level of exercise efficacy and exercise benefit of subjects in precontemplation/contemplation stage need to be enhanced in developing exercise program incorporating the stage of change for metabolic syndrome patients.

The Association between Physical Activity and Metabolic Syndrome Index in Middle-aged Adults (중년 성인의 신체활동과 대사증후군 지표의 관계)

  • So Youn Bang
    • Journal of Information Technology Applications and Management
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    • v.30 no.1
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    • pp.71-80
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    • 2023
  • The purpose of this study is to promote understanding of physical activity and metabolic syndrome in middle-aged adults and to provide basic data of interventions development for the prevention and management of metabolic syndrome. Using the 2020 data for Korea National Health and Nutrition Examination Survey, 1,786 middle-aged adults between the ages of 40 and 64 with no missing data were analyzed. As a result of the study, 56.5(±2.1)% of men and 52.9(±1.81)% of women were sufficient activity group among physical activity, and the proportion of men was higher than that of women, but it was not statistically significant(t=1.27, p=.207). The prevalence of metabolic syndrome was 38.9(±2.1%) of men and 25.4(±1.5)% of women, the prevalence of men was significantly higher than that of women(t=5.12, p<.001). Compared to the insufficient activity group, the sufficient activity group had a 0.71(95% CI: 0.57~0.88) times the risk of developing low HDL(high density lipoprotein)- cholesterol(p=.002), and this pattern was maintained even after adjusting for age, education level, body mass index, smoking status, and drinking status(p=.002). Based on the results of this study, a physical activity and metabolic syndrome risk group in middle-aged adults should be selected, and physical activity promotion program to improve high density lipoprotein-cholesterol among metabolic syndrome indicators should be developed.

Association Between Metabolic Syndrome and Adiponectin according to Sasang Constitution (사상체질에 따른 대사증후군과 Adiponectin의 상관성)

  • Yu, Jun-Sang;Koh, Sang-Baek;Park, Jong-Ku
    • Journal of Sasang Constitutional Medicine
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    • v.21 no.3
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    • pp.122-130
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    • 2009
  • 1. Objectives: The objective of this study is to investigate the relationship between adiponectin and metabolic syndrome according to Sasang Constitution. 2. Methods: Six hundred sixty six participants were included in this cohort study. Sex, age, BMI(Body Mass Index), smoking, drinking, adiponectin level and Metabolic syndrome components were considerd. Sasang constitutional diagnosis was carried out by a sasang constitutional specialist using photos, questionnaires and PSSC(Phonetic System for Sasang Classification). 3. Results: In binary logistic analysis after adjustment of age, sex, BMI, smoking, drinking, adiponectin level and sasang constitution were related with Metabolic syndrome. 4. Conclusions: We suggest that adiponectin and sasang constitution are the important biomarker in Metabolic syndorme.

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