• Title/Summary/Keyword: meta power

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A Meta-Analysis of Influencing Collagen Intake on Skin Utilizing Big Data (빅데이터 분석을 활용한 콜라겐 섭취가 피부에 미치는 영향에 관한 메타분석)

  • Jin, Chan-Yong;Yu, Ok-Kyeong;Nam, Soo-Tai
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.20 no.11
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    • pp.2033-2038
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    • 2016
  • Big data analysis, in the large amount of data stored as the data warehouse which it refers the process of discovering meaningful new correlations, patterns, trends and creating new values. The important issue of a meta-analysis is not the significance test, the effect size of the predictor variable on the criterion variable. We reviewed a total of 236 samples among 6 studies published on the topic related Collagen intake on skin between 2000 and 2016 in Korea. The results of the study are summarized as follows. First, we concluded that the path between before and after of Sebum (SB) had the largest effect size of (r = .416) Therefore, the effect of the Collagen intake intervention showed an explanatory power of 17 (%) about. Next, the path between before and after of Moisture (MS) had the higher the effect size of (r = .318). Thus, we present the theoretical and practical implications of these results.

Diagnostic performance of enzyme-linked immnosorbent assays for diagnosing paratuberculosis in cattle: a meta-analysis

  • Pak, Son-Il
    • Korean Journal of Veterinary Research
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    • v.44 no.4
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    • pp.669-676
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    • 2004
  • To evaluate the diagnostic accuracy of two commercial ELISA tests (Allied- and CSL-ELISA) for the diagnosis of Mycobacterium paratuberculosis in cattle, Meta-analysis using English language papers published during 1990-2001 was performed. Diagnostic odds ratios (DOR) were analyzed using regression analysis together with summary receiver operating characteristic (ROC) curves. The difference in diagnostic performance between the two ELISA systems was evaluated by using linear regression. Publication bias was assessed by funnel plot and linear regression. The pooled sensitivity and specificity were 44% (95% CI, 38 to 51) and 98% (95% CI, 96 to 99) for the random-effect model. The DOR between studies was heterogeneous. The area under the fitted ROC curve (AUC) was 0.72 for the unweighted and 0.77 for the weighted model. Maximum joint sensitivity and specificity for the unweighted and weighted model from their summary ROC curve were 70% and 75%, respectively. Based on the fitted model, at a specificity of 95%, sensitivity was estimated to be 52% for the unweighted and 57% for the weighted model. From the final multivariable model study characteristic, the country was the only significant variable with an explained component variance of 13.3%. There were no significant differences in discriminatory power, sensitivity, and specificity between the two ELISA tests. The overall diagnostic accuracy of two commercial ELISA tests was moderate, as judged by the AUC, maximum joint sensitivity and specificity, and estimates from the fitted model and clinical usefulness of the tests for screening program is limited because of low sensitivity and heterogeneous of DOR. It is, therefore, recommended to use ELISA tests as a parallel testing with other diagnostic tests together to increase test sensitivity in the screening program.

Minimally Invasive Procedure versus Conventional Redo Sternotomy for Mitral Valve Surgery in Patients with Previous Cardiac Surgery: A Systematic Review and Meta-Analysis

  • Muhammad Ali Tariq;Minhail Khalid Malik;Qazi Shurjeel Uddin;Zahabia Altaf;Mariam Zafar
    • Journal of Chest Surgery
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    • v.56 no.6
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    • pp.374-386
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    • 2023
  • Background: The heightened morbidity and mortality associated with repeat cardiac surgery are well documented. Redo median sternotomy (MS) and minimally invasive valve surgery are options for patients with prior cardiac surgery who require mitral valve surgery (MVS). We conducted a systematic review and meta-analysis comparing the outcomes of redo MS and minimally invasive MVS (MIMVS) in this population. Methods: We searched PubMed, EMBASE, and Scopus for studies comparing outcomes of redo MS and MIMVS for MVS. To calculate risk ratios (RRs) for binary outcomes and weighted mean differences (MDs) for continuous data, we employed a random-effects model. Results: We included 12 retrospective observational studies, comprising 4157 participants (675 for MIMVS; 3482 for redo MS). Reductions in mortality (RR, 0.54; 95% confidence interval [CI], 0.37-0.80), length of hospital stay (MD, -4.23; 95% CI, -5.77 to -2.68), length of intensive care unit (ICU) stay (MD, -2.02; 95% CI, -3.17 to -0.88), and new-onset acute kidney injury (AKI) risk (odds ratio, 0.34; 95% CI, 0.19 to 0.61) were statistically significant and favored MIMVS (p<0.05). No significant differences were observed in aortic cross-clamp time, cardiopulmonary bypass time, or risk of perioperative stroke, new-onset atrial fibrillation, surgical site infection, or reoperation for bleeding (p>0.05). Conclusion: The current literature, which primarily consists of retrospective comparisons, underscores certain benefits of MIMVS over redo MS. These include decreased mortality, shorter hospital and ICU stays, and reduced AKI risk. Given the lack of high-quality evidence, prospective randomized control trials with adequate power are necessary to investigate long-term outcomes.

Prediction of Consumed Electric Power on a MQL Milling Process using a Kriging Meta-Model (크리깅 메타모델을 이용한 MQL 밀링공정의 소비전력 예측 연구)

  • Jang, Duk-Yong;Jung, Jeehyun;Seok, Jongwon
    • Journal of the Korean Society for Precision Engineering
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    • v.32 no.4
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    • pp.353-358
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    • 2015
  • Energy consumption reduction has become an important key word in manufacturing that can be achieved through the efficient and optimal use of raw materials and natural resources, and minimization of the harmful effects on nature or human society. The successful implementation of this concept can only be possible by considering a product's entire life cycle and even its disposal from the early design stage. To accomplish this idea with milling, minimum quantity lubrication (MQL) strategies and cutting conditions are analyzed through process modeling and experiments. In this study, a model to predict the cutting energy in the milling process is used to find the cutting conditions, which minimize the cutting energy through a Kriging meta-modeling process. The MQL scheme is developed first to reduce the amount of cutting oil and costs used in the cutting process, which is then employed for the entire modeling and experiments.

A Study on the Performance Improvement of Harmony Search Optimization Algorithm (HS 최적화 알고리즘 성능 향상에 관한 연구)

  • Lee, Tae-Bong
    • Journal of Advanced Navigation Technology
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    • v.25 no.5
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    • pp.403-408
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    • 2021
  • Harmony Search(HS) algorithm is an emerging meta-heuristic optimization algorithm, which is inspired by the music improvisation process and has been successfully applied to solve different optimization problems. In order to further improve the performance of HS, this paper proposes a new method which is called Fast Harmony Search(FSH) algorithm. For the purpose, this paper suggest a method to unify two independent improvisation processes by newly defining the boundary value of a object variable using HM. As the result, the process time of the algorithm is shorten and explicit decision of bandwidth is no more needed. Furthermore, exploitative power of random selection is improved. The numerical results reveal that the proposed algorithm can find better solutions and is faster when compared to the conventional HS.

"Married Chastity": The Language of Paradox in Shakespeare's "The Phoenix and the Turtle" ("결혼한 순결"-「불사조와 산비둘기」와 역설의 언어)

  • Park, WooSoo
    • Journal of English Language & Literature
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    • v.59 no.4
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    • pp.527-544
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    • 2013
  • William Shakespeare's dirge, "The Phoenix and the Turtle," is still a crux in the Shakespearean canon and interpretation. The poem is still believed a dark allegory dealing with some arcane and obscure courtly matters and politics. However, we cannot recover its allegorical significance. This interpretive situation enforces us to read the poem as a self-conscious artwork in terms of its paradoxical language and meta-poetic metaphors. Paradox, as a subspecies of metaphor, challenges categorical and judgmental absolutes, and produces a sense of wonder in reconciling the logically contradictory opposites. In this poem the urn containing the ashes of the phoenix and the turtle is the icon of the mysterious unity of art, born of the wonderful marriage of male and female. Shakespeare's poem demonstrates in itself the magical power of poetic language in transforming an elegy into an epithalamion. The union of the phoenix and the turtle defies the singularity of their respective entity, and at the same time it retains their distinctive particularity of the two-ness. This neo-Platonic mystery of the "married chastity" is a paradox which confounds reason and verifies the poetic truth of imaginative intellect. The marriage of Christian perichoresis is crystallized in the artwork of the urn, which is admired at by posterity, though the marriage was issueless, due to its passing virtue. "The Phoenix and the Turtle" depicts the metaphor-making process and its effect, the poem.

Bayesian analysis of longitudinal traits in the Korea Association Resource (KARE) cohort

  • Chung, Wonil;Hwang, Hyunji;Park, Taesung
    • Genomics & Informatics
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    • v.20 no.2
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    • pp.16.1-16.12
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    • 2022
  • Various methodologies for the genetic analysis of longitudinal data have been proposed and applied to data from large-scale genome-wide association studies (GWAS) to identify single nucleotide polymorphisms (SNPs) associated with traits of interest and to detect SNP-time interactions. We recently proposed a grid-based Bayesian mixed model for longitudinal genetic data and showed that our Bayesian method increased the statistical power compared to the corresponding univariate method and well detected SNP-time interactions. In this paper, we further analyze longitudinal obesity-related traits such as body mass index, hip circumference, waist circumference, and waist-hip ratio from Korea Association Resource data to evaluate the proposed Bayesian method. We first conducted GWAS analyses of cross-sectional traits and combined the results of GWAS analyses through a meta-analysis based on a trajectory model and a random-effects model. We then applied our Bayesian method to a subset of SNPs selected by meta-analysis to further discover SNPs associated with traits of interest and SNP-time interactions. The proposed Bayesian method identified several novel SNPs associated with longitudinal obesity-related traits, and almost 25% of the identified SNPs had significant p-values for SNP-time interactions.

Thermal Flow Analysis of an Engine Room using a Porous Media Model for Imitating Flow Rate Reduction at Outlet of Industrial Machines (다공성 매질 모델 기반 출구유량 감소 모사 기법을 이용한 산업기계용 엔진룸 열유동해석)

  • Choi, Yo Han;Yoo, Il Hoon;Lee, Chul-Hee
    • Journal of Drive and Control
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    • v.19 no.1
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    • pp.62-68
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    • 2022
  • Considering the characteristics of industrial machines that lack vehicle-induced wind, forced convection by a cooling fan is mostly required. Therefore, numerical analysis of an engine room is usually performed to examine the cooling performance in the room. However, most engine rooms consist of a number of parts and components at specific positions, leading to high costs for numerical modeling and simulation. In this paper, a new methodology for three-dimensional computer-assisted design simplification was proposed, especially for the pile of components and parts at the engine room outlet. A porous media model and regression analysis were used to derive a meta-model for imitating the flow rate reduction at the outlet by the pile. The results showed that the fitted model was reasonable considering the coefficient of determination. The final numerical model of the engine room was then used to simulate the velocity distribution by changing the mass flow rate at the outlet. The results showed that both velocity distributions were significantly changed in each case and the meta-model was valid in imitating the flow rate reduction by some piles of components and parts.

An application of LAPO: Optimal design of a stand alone hybrid system consisting of WTG/PV/diesel generator/battery

  • Shiva, Navid;Rahiminejad, Abolfazl;Nematollahi, Amin Foroughi;Vahidi, Behrooz
    • Advances in Energy Research
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    • v.7 no.1
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    • pp.67-84
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    • 2020
  • Given the recent surge of interest towards utilization of renewable distributed energy resources (DER), in particular in remote areas, this paper aims at designing an optimal hybrid system in order to supply loads of a village located in Esfarayen, North Khorasan, Iran. This paper illustrates the optimal design procedure of a standalone hybrid system which consists of Wind Turbine Generator (WTG), Photo Voltaic (PV), Diesel-generator, and Battery denoting as the Energy Storage System (ESS). The WTGs and PVs are considered as the main producers since the site's ambient conditions are suitable for such producers. Moreover, batteries are employed to smooth out the variable outputs of these renewable resources. To this end, whenever the available power generation is higher than the demanded amount, the excess energy will be stored in ESS to be injected into the system in the time of insufficient power generation. Since the standalone system is assumed to have no connection to the upstream network, it must be able to supply the loads without any load curtailment. In this regard, a Diesel-Generator can also be integrated to achieve zero loss of load. The optimal hybrid system design problem is a discrete optimization problem that is solved, here, by means of a recently-introduced meta-heuristic optimization algorithm known as Lightning Attachment Procedure Optimization (LAPO). The results are compared to those of some other methods and discussed in detail. The results also show that the total cost of the designed stand-alone system in 25 years is around 92M€ which is much less than the grid-connected system with the total cost of 205M€. In summary, the obtained simulation results demonstrate the effectiveness of the utilized optimization algorithm in finding the best results, and the designed hybrid system in serving the remote loads.

An Innovative Fast Relay Coordination Method to Bypass the Time Consumption of Optimization Algorithms in Relay Protection Coordination

  • Kheshti, Mostafa;Kang, Xiaoning;Jiao, Zaibin
    • Journal of Electrical Engineering and Technology
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    • v.12 no.2
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    • pp.612-620
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    • 2017
  • Relay coordination in power system is a complex problem and so far, meta-heuristic algorithms and other methods as an alternative approach may not properly deal with large scale relay coordination due to their huge time consuming computation. In some cases the relay coordination could be unachievable. As the urgency for a proper approach is essential, in this paper an innovative and simple relay coordination method is introduced that is able to be applied on optimization algorithms for relay protection coordination. The objective function equation of operating time of relays are divided into two separate functions with less constraints. As the analytical results show here, this equivalent method has a remarkable speed with high accuracy to coordinate directional relays. Two distribution systems including directional overcurrent relays are studied in DigSILENT software and the collected data are examined in MATLAB. The relay settings of this method are compared with particle swarm optimization and genetic algorithm. The analytical results show the correctness of this mathematical and practical approach. This fast coordination method has a proper velocity of convergence with low iteration that can be used in large scale systems in practice and also to provide a feasible solution for protection coordination in smart grids as online or offline protection coordination.