• Proceedings of the Korean Society of Applied Pharmacology
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• 2003.11a
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• pp.64-64
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• 2003

It is thought that highly reactive oxygen radicals generated at the ischemia-reperfusion in case of strokes play an important role in damaging the brain. We examined the neuroprotective effects from the several medicinal herbs in the transient ischemic rat model and compared their effects with the free radical scavenging activities. Transient ischemia was induced by intraluminal occusion of the right middle cerebral artety for 120 min and reperfusion was continued for 22 h in rats. The free radical scavenging properties of medicinal herbs were examined in vitro by determination of the interaction with the 1,l-diphenyl-2-picrylhydrazyl (DPPH) stable free radical. Aqueous extracts of 11 medicinal herbs (200 mg/kg) were orally administered, promptly prior to reperfusion and 2 h after reperfusion. Total infarction volume in the ipsilateral hemisphere of ischemia reperfusion rats was significantly lowered by the treatment of 7 medicinal herbs (Sophora flavescens, Lycopus lucidus, Sanguisorba officinalis, Caesalpinia sappan, Albizia julibrissin, Rubia akane, Psoralea corylifolia, Prunella vulgaris). However, all of these medicinal herbs did not show antioxidative activities. These results suggest that neuroprotective effects of several drugs are not always correlated with their antioxidative properties.

• Korean Journal of Medicinal Crop Science
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• v.27 no.2
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• pp.126-135
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• 2019

Background: The ginseng ginsenosides, which have various physiological activities, are known to be more abundant in the leaves than in the roots, and the consumers' interest in ginseng sprout as a functional vegetable has been increasing. Methods and Results: The aim of this study was to investigate the effects of growth period on growth properties, active ingredients and rheology of ginseng sprouts cultivated in a non-heated greenhouse equipped with a shade net for 60 days, starting from the end of May to the middle of July. The chlorophyll content of the leaves decreased, but their length and width increased with increasing cultivation days. In particular, growth increased significantly until 40 days, but only slightly after 50 days. The stem length did not increase greatly from the 20 th to the 30 th day of cultivation, but increased significantly from the 30 th to the 40 th day, and then further increased gradually. The weight of the leaves, stems, and roots increased slightly, but not change significantly. After 40 days of cultivation, the total ginsenoside content increased by 1.07 times in the leaves and decreased by 0.80 times in the roots with increasing cultivation days. The leaf contents of ginsenosides $Rg_1$, Re, $Rb_1$, Rc, $F_3$ and $F_4$ increased with increasing cultivation days. The rheological properties of ginseng sprout showed the greatest influence on stem hardening with increasing cultivation days. Conclusions: Therefore, based on the growth characteristics, active ingredients and physical properties, 40 days after sowing was considered to be an appropriate harvesting time for ginseng sprouts.

• Mycobiology
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• v.42 no.3
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• pp.215-220
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• 2014

Mushrooms are a recognized component of the human diet, with versatile medicinal properties. Some mushrooms are popular worldwide for their nutritional and therapeutic properties. However, some species are dangerous because they cause toxicity. There are many reports explaining the medicinal and/or toxic effects of these fungal species. Cases of serious human poisoning generally caused by the improper identification of toxic mushroom species are reported every year. Different substances responsible for the fatal signs and symptoms of mushroom toxicity have been identified from various poisonous mushrooms. Toxicity studies of mushroom species have demonstrated that mushroom poisoning can cause adverse effects such as liver failure, bradycardia, chest pain, seizures, gastroenteritis, intestinal fibrosis, renal failure, erythromelalgia, and rhabdomyolysis. Correct categorization and better understanding are essential for the safe and healthy consumption of mushrooms as functional foods as well as for their medicinal use.

• CELLMED
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• v.5 no.3
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• pp.17.1-17.22
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• 2015

Apart from being used as food, seed oils have also been used traditionally as medicinal products by several communities. However, the full medicinal potential of many seed oil plants is yet to be properly reviewed, particularly for their antimicrobial and antioxidant properties. North-East India has rich resources of seed oil plants. The availability of detailed information on these plants is quite limited. This review aims to explore and evaluate these seed oil plants of the North-East India with particular emphasis on their antimicrobial and antioxidant activities as well as chemical compositions. A comprehensive literature search on seed oil plants of this region has been performed. Seed oil yielding plants of this region can be categorized into two categories: plants that are used traditionally as sources of edible or medicinal oils and plants that are used for purposes other than as sources of oils. Many seed oil plants of this region have been reported to possess antimicrobial and antioxidant properties, and to produce various types of compounds. This review also highlights the importance of these plants in contributing to the local as well as the national economy of India.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.3
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• pp.753-758
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• 2006

This study was performed to provide basic ideas as understanding and application for oriental medicinal cuisine (Yak-Sun). We investigated background, history of Yak-Sun in China. Also we conducted to investigated how to apply the theories of oriental medicine appropriately, which direction should be taken, and how it should be developed. To develop medicinal cuisine, it is necessary to grasp the theoretical system. And to develop medicinal cuisine for health enhancement, it is also required not only to consider constitutions but also to suggest the need of knowledge for moderation in terms of regimen along with the theory of oriental medicine. Also to develop medicinal cuisine according to the perspective of oriental medicinal theory, what should be taken into account is not only the understanding of the characteristics of food materials, but also the properties of them that the theory of oriental medicine. Lastly the scientific effect of the medicinal cuisine which is developed according to the oriental medicinal theory. And it is believed to be essential for the government to make effects to set a standard and laws to validate the medicinal effects and the process of assessment so that the systematic development can be encouraged, and to prepare guidance to food development for national health improvement.

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.3
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• pp.373-381
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• 2011

Liu Hejian maintained that the six types of energy can become fire and focused on the treatment of fire and heat symptoms along with the prescriptions of cryotherapy, believing that a vast majority of disease are due to fire. In this study, we investigated the characteristics of Hejian's formulae by classifying medicinal ingredients in consideration of medicinal properties and efficacy in order to examine how many cold and hot medicinal ingredients are included in the formulae of Hejian. We analysis 848 formulae among 1,055 formulae in total, excluding 207 redundant ones, which includes 366 Sunmyunglon formulae, 223 Bomyeongjip formulae, 8 Samsolon formulae, 61 Sanghanjigkyeok formulae, 68 Sanghanpyobon formulae, 22 Sanghansimyo formulae, 103 Hwalbeopgiyo formulae, 186 Bodongbiyo formulae, and 18 Gagamyoungbisippalbang formulae. In the analysis of the frequency of using each medicinal herb after classifying medicinal ingredients of Hejian's formulae by medicinal properties, we found that cold medicinal ingredients accounted for 40%, the biggest share in the formulae, and hot medicinal ingredients accounted for around 45%, which indicates that Hejian's formulae consist of both elimination and reinforcement and cold and heat, rather than cold medicinal ingredients only. As a comparison of the frequency of using each medicinal ingredients for the formulae by efficacy, we found that clear heat medicinal ingredients, totify qi and replenish blood medicinal herbs, and activate blood medicinal ingredients were most frequently used.

• Journal of Physiology & Pathology in Korean Medicine
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• v.19 no.6
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• pp.1520-1527
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• 2005

This study was peformed to provide basic ideas as understanding and application for oriental medicinal cuisine (Yak-Sun). We investigated background, history of Yak-Sun in China. Also we conducted to investigated how to apply the theories of oriental medicine appropriately, which direction should be taken, and how it should be developed. To develop medicinal cuisine, it is necessary to grasp the theoretical system. And to develop medicinal cuisine for health enhancement, it is also required not only to consider constitutions but also to suggest the need of knowledge for moderation in terms of regimen along with the theory of oriental medicine. Also to develop medicinal cuisine according to the perspective of oriental medicinal theory, what should be taken into account is not only the understanding of the characteristics of food materials, but also the properties of them that the theory of oriental medicine. Lastly the scientific effect of the medicinal cuisine which is developed according to the oriental medicinal theory. And it is believed to be essential for the government to make effects to set a standard and laws to validate the medicinal effects and the process of assessment so that the systematic development can be encouraged, and to prepare guidance to food development for national health improvement.

• The Korea Journal of Herbology
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• v.21 no.3
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• pp.35-45
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• 2006

Objectives : The plans can be used for medicinal purposes among Alismatales in korea and examined their effects and distributions. Methods : The examined herbalogical books and research papers which published at home and abroad. Results : 1. There were totaled to 15 genera and 45 species in Alismatales in Korea and among them medicinal plants are 8 genera, 17 species, some 38% in total. 2. Potamogeton genus is main kind enough that it has 14 species among 45 species in the Alismatales , of which medicinal plants are 6 species. 3. The herb is the main medicinal parts of medicinal plants in the Alismatales which is used in 14 species. 4. According to nature and flavor of medicinal plants in the Alismatales , they were classified into cool 8 species; sweet taste 10 in the order. 5. According to meridian propism of medicinal plants in the Alismatales, they were classified into liver meridian 8 species. 6. According to the properties and principal curative action, they were classified into drugs for antifebrile 12 species, drugs for detoxicant 11 , drugs for drain damp 9 in the order. 7. It was noticed that every medicinal plant in the Alismatales is nontoxic. Conclusion : There were totaled to 15 genera and 45 species in Alismatales in Korea and among them medicinal plants are 8 genera, 17 species, some 38% in total.

• Journal of Korean Society of Forest Science
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• v.109 no.3
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• pp.313-324
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• 2020

This study investigated the environmental location effects that Larix kaempferi and mixed forests had on the early growth of wild-simulated ginseng (Panax ginseng C. A. Meyer) seedlings. Experimental plots were created in Larix kaempferi and mixed forests, and confirmed the location environments and growth characteristics of wild-simulated ginseng seedling. Our results showed that the soil properties, such as soil organic matter, total nitrogen, and cation exchangeable capacity were significantly higher in the mixed forest soil compared to the Larix kaempferi forest soil. Likewise, the growth characteristics of wild-simulated ginseng seedlings were significantly higher in mixed forestsd compare to the Larix kaempferi forest. Correlation analysis between tree species ratio, soil properties, and growth characteristics in the experimental plots determined that the soil properties and growth characteristics had significant positive correlation with the broad-leaved forest percentage. Growth characteristics of the wild-simulated ginseng seedlings were shown to have a significant positive correlation with organic matter, total nitrogen, and cation exchange capacities. This study has clearly demonstrated that the tree species ratio, and soil properties in Larix kaempferi and mixed forests were significantly correlated with the early growth of wild simulated ginseng seedlings. These results could help to improve the selection of suitable cultivation sites for wild-simulated ginseng.

• Korean Journal of Plant Resources
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• v.33 no.6
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• pp.651-658
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• 2020

The aim of this study was to investigate the comparative growth characteristics and ginenoside contents of wild-simulated ginseng on different years (7 and 13-year-old) by monitoring soil properties of cultivation regions. Plant and soil samples were collected from 6 different cultivation regions. Soil organic matter (OM), total nitrogen (TN) and cation exchangeable capacity (CEC) were significantly higher in 13-year-old wild-simulated ginseng cultivation regions compared to 7-year-old wild-simulated ginseng cultivation regions. Growth characteristics of wild-simulated ginseng had shown significantly higher in 13-year-old wild-simulated ginseng compared to 7-year-old wild-simulated ginseng. Ginsenoside G-Rb1, Rb2, Rc, Rd, Re, Rf, Rg1 were significantly higher in 13-year-old wild-simulated ginseng than 7-year-old wild-simulated ginseng. According to the results of correlation analysis, soil OM, TN and CEC of the cultivated regions were positively correlated with the growth of wild-simulated ginseng. In addition, the root length of wild-simulated ginseng showed positive correlation with ginsenoside content. Hence, this study was able to investigate the correlation between growth and ginsenoside content of wild-simulated ginseng based on soil characteristics of the cultivation regions.