• Journal of Yeungnam Medical Science
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• v.27 no.2
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• pp.98-104
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• 2010

Primary anterior mediastinal neoplasms comprise a diverse group of tumors and account for 50% of all mediastinal masses. Thymic epithelial neoplasm are most common and classified into thymoma, invasive thymoma, and thymic carcinoma. Neuroendocrine differentiation of thymic epithelial neoplasm are rare malignancies. Germ cell tumor (GCT) is second most common anterior mediastinal tumor and most of them are mature cystic teratoma. Malignant mediastinal GCT are rare than benign. Primary thoracic lymphoma is rare than thoracic involvement of systemic lymphoma and most common location of primary thoracic lymphoma is anterior mediastinum. The clinical and radiologic appearance of the most common masses are reviewed.

• Journal of Chest Surgery
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• v.17 no.2
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• pp.299-304
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• 1984

Tumors of the mediastinum are usually classified according to their location in the anterior, middle, or posterior mediastinum. Mediastinal teratomas are characteristically located at anterior mediastinum with only rare incidence in the posterior mediastinum. Two cases of posterior mediastinal teratoma were experienced recently, in the department of thoracic surgery, Seoul National University Hospital. The incidence of posterior mediastinal teratoma was 4.2% among 48 mediastinal teratomas in our experience. Two cases are all benign teratoma located at right posterior costophrenic angle, and histologically showed tissues from three germ layers including bone and fat.

• Journal of Chest Surgery
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• v.16 no.3
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• pp.375-380
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• 1983

The lipomatous of the mediastinum are fairly uncommon tumors. Since 1971, two patients with proven mediastinal lipoma and one primary liposarcoma of the mediastinum have been treated at the Seoul National University Hospital. This report reviews our experience with the review of literature. Case 1.: A 3 year old body revealed a huge round homogenous mass density in the posterior mediastinum in routine chest X-ray. The tumor mass, lipoma, was successfully removed and postoperative course was uneventful. Cases 2.: An asymptomatic 24 year old male was operated on with the preoperative diagnosis of mediastinal lipoma. His preoperative chest X-ray and CT films showed a huge anterior to middle mediastinal tumor, right, with fat density. There is no postoperative problem after successful removal of the tumor mass. Case 3. : A 24 year old female was hospitalized with the complaints of cough and chest pain. A mediastinal mass was removed, which proved to be a liposarcoma on pathologic examination. About one year later, she was found to have recurrent liposarcoma in the right chest area at the OPD follow-up. She was lost to follow-up since then.

• Journal of Chest Surgery
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• v.29 no.6
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• pp.632-638
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• 1996

A retrospective analysis of primary mediastinal tumors and cysts was performed on 42 patients who underwent surgical resection at our institution from january, 1985 to December, 1995. The patients consisted of 27 males and 15 females. The mean age was 40 years with a range of 10 month to 76 years. The patients were composed of thymlc tumor 12 cases (28.6 %), germ cell tumor 8 cases (19.0 %), primary cyst 7 cases (16.7 %), neurogenic tumor 6 cases (14.3 %) and other miscellanious tumor 9 cases. Overall, 3) (78.6 %) of the tumors were histologically benign, and 9 (21.4 %) were malig- nant. The noted clinical manifestations were respiratory symptoms such as chest pain, dyspnea and coughing. All of the patients with malignancy and 55 oyo of the patients with benign tumor were symptomatic on presentation. All of the patients were operated for tis ue diagnosis and curative resection. All the benign tumors ex- cept two cases of sarcoidosis were performed adequate curative resection. A few patients with malignant unresectable tumors were treated with chemotherapy or radiotherapy There were 7 (18 %) postoperative complications without mortality. In conclusion, Mediastinal tumors have long fascinated the thoracic surgeon because of their variety and unpredictability of diagnosis prior to exploration. We consider that active surgery and various combined modality can be accomplished with satisfactory result.

• Journal of Chest Surgery
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• v.8 no.2
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• pp.169-172
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• 1975

• Journal of Chest Surgery
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• v.30 no.7
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• pp.708-712
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• 1997

We report on nine years experience of surgical treatment of mediastinal tumors in 47 patients. Their ages ranged from 5 o 67 years with an average of 36.4 years and the sex ratio of male and female was 1:1.5. The most frequent symptom was chest pain(27.7%), followed by ptosis(14.9%), general weatuless(12.8%) and eight patients(17.0%) were asymptomatic. The most prevalent location of the tumor was anterosuperior mediastinum(63.8%). Pathologically, thymoma(32.9%) was the most common tumor, followed by cyst(21.3%), neurogenic tumor(17.0%), germ cell tumor(12.8%), and mesenchymal tumor(6.4%). Complete removal was achieved in 41 cases of all benign tumors and 3 cases of malignant tumors. All the malignant tumor patients were treated with chemotherapy, radiotherapy or both after surgery. Postoperative complications developed in 4 cases and there was no operative death.

• Journal of Chest Surgery
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• v.12 no.2
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• pp.97-100
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• 1979

Primary intrathoracic neoplasms occur frequently, and the most frequent intrathoracic tumors are of pulmonary or bronchogenic origin. Second in frequency are mediastinal tumors, and least frequency or comparatively rare are the neoplasms arising from the wall of the thorax and extending into the thoracic cavity. Of all intrathoracic tumors, fibroma is extremely rare. Recently, we have experienced a huge rapid growing intrathoracic fibroma originating from thoracic wall, which is removed successfully and confirmed histopathologically. Authors present one case of fibroma and discussion with a brief review of the relevant literatures.

• Journal of Chest Surgery
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• v.30 no.1
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• pp.55-60
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• 1997

We reviewed 40 cases of primary mediastinal tumors which were operated on at Seoul Paik Hospital from September, 1987 to December, 1995. Of these, 18 were male and 22 were female. The patient ranged in age from 4 years to 68 years with a mean age of 34.1 years. The most common symptoms included chest pain(12.5%), cough(12.5%), dyspnea(7.5%). and palpable neck mass(7.5%), and symptoms were absent at the time of diagnosis in 37.5% of cases. Chest roentgenography and computed tomography(CT) were performed in all patients, and magnetic resonance imaging(MRI) in 5 patients, and transthoracic needle aspiration (TTNA) performed In 22 patients. The sensitivity of TTNA was 72.7%(16 of 22 patients). The lesion was located 60% in the anterosuperior mediastinum, 35% in the posterior mediastinum, and 5% in the middle mediastinum. The primary tumors included thymic neoplasms(11 cases), germ cell tumors(7 cases), neurogenic tumors(10 cases) and a miscellaneous group. The malignant tumors(12.5%) were invasive thymoma(3 cases), spindle cell sarcoma(1 case), and non-Hodgkin's Iymphoma(1 case). A complete excision was done in all 35 benign tumors and 3 malignant tumors. There was no operative mortality, and postoperative complications occurred in 3 cases.

• Journal of Chest Surgery
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• v.47 no.2
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• pp.197-199
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• 2014

Mediastinal paragangliomas are very rare neuroendocrine tumors. Complete resection is the standard treatment of a paraganglioma because of the tumor's potential malignancy and poor response to chemo- or radiotherapy. However, the highly vascular nature of the tumor and its characteristic anatomic location make complete resection difficult. We report a case of an anterior mediastinal paraganglioma, which was incidentally found on a chest computed tomography scan for chronic cough work-up of a 55-year-old woman. Complete resection was accomplished using video-assisted thoracoscopic surgery, and the patient recovered without any complications.

• Journal of Chest Surgery
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• v.46 no.2
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• pp.156-158
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• 2013

Thoracic extramedullary hematopoiesis (EMH) is a rare disease entity that is usually associated with hematologic disorders, such as myelodysplastic or hemolytic disease. Because thoracic EMH is usually encountered as a mass during radiologic examinations, it should be differentiated from posterior mediastinal neurogenic tumors. Here, the authors report a case of EMH associated with hereditary spherocytosis. The patient underwent a complete excision by thoracoscopic surgery to differentiate it from other mediastinal tumors.